#ID = Affymetrix Probe Set ID #GB_ACC = GenBank Accession Number #SPOT_ID = identifies controls #Species Scientific Name = The genus and species of the organism represented by the probe set. #Annotation Date = The date that the annotations for this probe array were last updated. It will generally be earlier than the date when the annotations were posted on the Affymetrix web site. #Sequence Type = #Sequence Source = The database from which the sequence used to design this probe set was taken. #Target Description = #Representative Public ID = The accession number of a representative sequence. Note that for consensus-based probe sets, the representative sequence is only one of several sequences (sequence sub-clusters) used to build the consensus sequence and it is not directly used to derive the probe sequences. The representative sequence is chosen during array design as a sequence that is best associated with the transcribed region being interrogated by the probe set. Refer to the "Sequence Source" field to determine the database used. #Gene Title = Title of Gene represented by the probe set. #Gene Symbol = A gene symbol, when one is available (from UniGene). #ENTREZ_GENE_ID = Entrez Gene Database UID #RefSeq Transcript ID = References to multiple sequences in RefSeq. The field contains the ID and Description for each entry, and there can be multiple entries per ProbeSet. #Gene Ontology Biological Process = Gene Ontology Consortium Biological Process derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". #Gene Ontology Cellular Component = Gene Ontology Consortium Cellular Component derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". #Gene Ontology Molecular Function = Gene Ontology Consortium Molecular Function derived from LocusLink. Each annotation consists of three parts: "Accession Number // Description // Evidence". The description corresponds directly to the GO ID. The evidence can be "direct", or "extended". ID GB_ACC SPOT_ID Species Scientific Name Annotation Date Sequence Type Sequence Source Target Description Representative Public ID Gene Title Gene Symbol ENTREZ_GENE_ID RefSeq Transcript ID Gene Ontology Biological Process Gene Ontology Cellular Component Gene Ontology Molecular Function 1007_s_at U48705 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database U48705 /FEATURE=mRNA /DEFINITION=HSU48705 Human receptor tyrosine kinase DDR gene, complete cds U48705 discoidin domain receptor tyrosine kinase 1 DDR1 780 NM_001954 /// NM_013993 /// NM_013994 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 1053_at M87338 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank M87338 /FEATURE= /DEFINITION=HUMA1SBU Human replication factor C, 40-kDa subunit (A1) mRNA, complete cds M87338 replication factor C (activator 1) 2, 40kDa RFC2 5982 NM_002914 /// NM_181471 0006260 // DNA replication // not recorded /// 0006260 // DNA replication // inferred from electronic annotation /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003689 // DNA clamp loader activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 117_at X51757 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database X51757 /FEATURE=cds /DEFINITION=HSP70B Human heat-shock protein HSP70B' gene X51757 heat shock 70kDa protein 6 (HSP70B') HSPA6 3310 NM_002155 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0006986 // response to unfolded protein // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 121_at X69699 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank X69699 /FEATURE= /DEFINITION=HSPAX8A H.sapiens Pax8 mRNA X69699 paired box 8 PAX8 7849 NM_003466 /// NM_013951 /// NM_013952 /// NM_013953 /// NM_013992 0001656 // metanephros development // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004996 // thyroid-stimulating hormone receptor activity // traceable author statement /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from sequence or structural similarity /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 1255_g_at L36861 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database L36861 /FEATURE=expanded_cds /DEFINITION=HUMGCAPB Homo sapiens guanylate cyclase activating protein (GCAP) gene exons 1-4, complete cds L36861 guanylate cyclase activator 1A (retina) GUCA1A 2978 NM_000409 0007165 // signal transduction // non-traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0007602 // phototransduction // inferred from electronic annotation /// 0031282 // regulation of guanylate cyclase activity // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008048 // calcium sensitive guanylate cyclase activator activity // traceable author statement /// 0008048 // calcium sensitive guanylate cyclase activator activity // inferred from electronic annotation /// 0030249 // guanylate cyclase regulator activity // inferred from electronic annotation 1294_at L13852 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank L13852 /FEATURE= /DEFINITION=HUME1URP Homo sapiens ubiquitin-activating enzyme E1 related protein mRNA, complete cds L13852 ubiquitin-like modifier activating enzyme 7 UBA7 7318 NM_003335 0006464 // protein modification process // inferred from direct assay /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019941 // modification-dependent protein catabolic process // inferred from electronic annotation /// 0032020 // ISG15-protein conjugation // inferred from direct assay /// 0032020 // ISG15-protein conjugation // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019782 // ISG15 activating enzyme activity // inferred from direct assay /// 0019782 // ISG15 activating enzyme activity // inferred from electronic annotation 1316_at X55005 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database X55005 /FEATURE=mRNA /DEFINITION=HSCERBAR Homo sapiens mRNA for thyroid hormone receptor alpha 1 THRA1, (c-erbA-1 gene) X55005 thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) THRA 7067 NM_003250 /// NM_199334 0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006351 // transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0008016 // regulation of heart contraction // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from electronic annotation /// 0043433 // negative regulation of transcription factor activity // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003727 // single-stranded RNA binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // traceable author statement /// 0004887 // thyroid hormone receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 1320_at X79510 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database X79510 /FEATURE=cds /DEFINITION=HSPTPD1 H.sapiens mRNA for protein-tyrosine-phosphatase D1 X79510 protein tyrosine phosphatase, non-receptor type 21 PTPN21 11099 NM_007039 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 1405_i_at M21121 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank M21121 /FEATURE= /DEFINITION=HUMTCSM Human T cell-specific protein (RANTES) mRNA, complete cds M21121 chemokine (C-C motif) ligand 5 CCL5 6352 NM_002985 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0006887 // exocytosis // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0006935 // chemotaxis // traceable author statement /// 0006935 // chemotaxis // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0006968 // cellular defense response // traceable author statement /// 0006979 // response to oxidative stress // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0045071 // negative regulation of viral genome replication // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008009 // chemokine activity // traceable author statement /// 0008009 // chemokine activity // inferred from electronic annotation /// 0042056 // chemoattractant activity // inferred from direct assay 1431_at J02843 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database J02843 /FEATURE=cds /DEFINITION=HUMCYPIIE Human cytochrome P450IIE1 (ethanol-inducible) gene, complete cds J02843 cytochrome P450, family 2, subfamily E, polypeptide 1 CYP2E1 1571 NM_000773 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // not recorded /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050381 // unspecific monooxygenase activity // inferred from electronic annotation 1438_at X75208 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database X75208 /FEATURE=cds /DEFINITION=HSPTKR H.sapiens HEK2 mRNA for protein tyrosine kinase receptor X75208 EPH receptor B3 EPHB3 2049 NM_004443 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007411 // axon guidance // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008046 // axon guidance receptor activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 1487_at L38487 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database L38487 /FEATURE=mRNA /DEFINITION=HUMHERRA1 Human estrogen receptor-related protein (hERRa1) mRNA, 3' end, partial cds L38487 estrogen-related receptor alpha ESRRA 2101 NM_004451 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1494_f_at M33318 Homo sapiens Mar 11, 2009 Exemplar sequence Affymetrix Proprietary Database M33318 /FEATURE=mRNA /DEFINITION=HUMCPIIA3A Human cytochrome P450IIA3 (CYP2A3) mRNA, complete cds M33318 cytochrome P450, family 2, subfamily A, polypeptide 6 CYP2A6 1548 NM_000762 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // traceable author statement /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0004497 // monooxygenase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008389 // coumarin 7-hydroxylase activity // not recorded /// 0008389 // coumarin 7-hydroxylase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016712 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen // inferred from electronic annotation /// 0019825 // oxygen binding // traceable author statement /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050381 // unspecific monooxygenase activity // inferred from electronic annotation 1598_g_at L13720 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank L13720 /FEATURE= /DEFINITION=HUMGAS Homo sapiens growth-arrest-specific protein (gas) mRNA, complete cds L13720 growth arrest-specific 6 /// similar to growth arrest-specific 6 GAS6 /// LOC100133684 100133684 /// 2621 NM_000820 /// XM_001716774 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031100 // organ regeneration // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0005102 // receptor binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 160020_at Z48481 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Z48481 /FEATURE=cds /DEFINITION=HSMMPM1 H.sapiens mRNA for membrane-type matrix metalloproteinase 1 /NOTE=replacement of probe set 1301_s_at Z48481 matrix metallopeptidase 14 (membrane-inserted) MMP14 4323 NM_004995 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from electronic annotation /// 0001935 // endothelial cell proliferation // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009725 // response to hormone stimulus // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031638 // zymogen activation // inferred from electronic annotation /// 0043615 // astrocyte cell migration // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0048754 // branching morphogenesis of a tube // inferred from electronic annotation /// 0048771 // tissue remodeling // inferred from electronic annotation /// 0051895 // negative regulation of focal adhesion formation // inferred from electronic annotation 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004222 // metalloendopeptidase activity // traceable author statement /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016504 // protease activator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 1729_at L41690 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank L41690 /FEATURE= /DEFINITION=HUMTRADD Homo sapiens TNF receptor-1 associated protein (TRADD) mRNA, 3' end of cds L41690 TNFRSF1A-associated via death domain TRADD 8717 NM_003789 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0006917 // induction of apoptosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0008633 // activation of pro-apoptotic gene products // not recorded /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from expression pattern /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from electronic annotation /// 0051798 // positive regulation of hair follicle development // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // inferred from electronic annotation 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019215 // intermediate filament binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 1773_at L00635 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank L00635 /FEATURE= /DEFINITION=HUMFPTB Human farnesyl-protein transferase beta-subunit mRNA, complete cds L00635 farnesyltransferase, CAAX box, beta FNTB 2342 NM_002028 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0018347 // protein amino acid farnesylation // traceable author statement /// 0042060 // wound healing // inferred from electronic annotation /// 0045941 // positive regulation of transcription // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004311 // farnesyltranstransferase activity // inferred from electronic annotation /// 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // traceable author statement /// 0004660 // protein farnesyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 177_at U38545 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank U38545 /FEATURE= /DEFINITION=HSU38545 Human ARF-activated phosphatidylcholine-specific phospholipase D1a (hPLD1) mRNA, complete cds U38545 phospholipase D1, phosphatidylcholine-specific PLD1 5337 NM_001130081 /// NM_002662 0006935 // chemotaxis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation 179_at U38980 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank U38980 /FEATURE= /DEFINITION=U38980 Human PMS2 related (hPMSR6) mRNA, complete cds U38980 postmeiotic segregation increased 2-like 11 pseudogene PMS2L11 441263 NR_023383 /// XM_001715908 /// XM_001717503 0006298 // mismatch repair // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030983 // mismatched DNA binding // inferred from electronic annotation 1861_at U66879 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank U66879 /FEATURE= /DEFINITION=HSU66879 Human Bcl-2 binding component 6 (bbc6) mRNA, complete cds U66879 BCL2-associated agonist of cell death BAD 572 NM_004322 /// NM_032989 0006007 // glucose catabolic process // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // non-traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // inferred from electronic annotation /// 0008632 // apoptotic program // traceable author statement /// 0008633 // activation of pro-apoptotic gene products // not recorded /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0043281 // regulation of caspase activity // inferred from electronic annotation /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // not recorded /// 0005741 // mitochondrial outer membrane // non-traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement 200000_s_at NM_006445 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006445.1 /DEF=Homo sapiens U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p (PRP8), mRNA. /FEA=mRNA /GEN=PRP8 /PROD=U5 snRNP-specific protein (220 kD), ortholog ofS. cerevisiae Prp8p /DB_XREF=gi:5453983 /UG=Hs.181368 U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p /FL=gb:AB007510.1 gb:AF092565.1 gb:NM_006445.1 NM_006445 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) PRPF8 10594 NM_006445 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005682 // snRNP U5 // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200001_at NM_001749 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001749.1 /DEF=Homo sapiens calpain 4, small subunit (30K) (CAPN4), mRNA. /FEA=mRNA /GEN=CAPN4 /PROD=calpain 4 small subunit /DB_XREF=gi:4502564 /UG=Hs.74451 calpain 4, small subunit (30K) /FL=gb:BC000592.1 gb:NM_001749.1 NM_001749 calpain, small subunit 1 CAPNS1 826 NM_001003962 /// NM_001749 0008284 // positive regulation of cell proliferation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004198 // calcium-dependent cysteine-type endopeptidase activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200002_at NM_007209 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007209.1 /DEF=Homo sapiens ribosomal protein L35 (RPL35), mRNA. /FEA=mRNA /GEN=RPL35 /PROD=ribosomal protein L35 /DB_XREF=gi:6005859 /UG=Hs.182825 ribosomal protein L35 /FL=gb:BC000348.1 gb:U12465.1 gb:NM_007209.1 NM_007209 ribosomal protein L35 RPL35 11224 NM_007209 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003729 // mRNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200003_s_at NM_000991 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000991.1 /DEF=Homo sapiens ribosomal protein L28 (RPL28), mRNA. /FEA=mRNA /GEN=RPL28 /PROD=ribosomal protein L28 /DB_XREF=gi:4506626 /UG=Hs.4437 ribosomal protein L28 /FL=gb:BC000072.1 gb:NM_000991.1 gb:U14969.1 NM_000991 ribosomal protein L28 RPL28 6158 NM_000991 /// NM_001136134 /// NM_001136135 /// NM_001136136 /// NM_001136137 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200004_at NM_001418 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001418.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2), mRNA. /FEA=mRNA /GEN=EIF4G2 /PROD=eukaryotic translation initiation factor 4gamma, 2 /DB_XREF=gi:4503538 /UG=Hs.183684 eukaryotic translation initiation factor 4 gamma, 2 /FL=gb:U73824.1 gb:U76111.1 gb:NM_001418.1 NM_001418 eukaryotic translation initiation factor 4 gamma, 2 EIF4G2 1982 NM_001042559 /// NM_001418 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0007050 // cell cycle arrest // traceable author statement /// 0008219 // cell death // traceable author statement /// 0016070 // RNA metabolic process // inferred from electronic annotation 0016281 // eukaryotic translation initiation factor 4F complex // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // inferred from direct assay /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 200005_at NM_003753 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003753.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) (EIF3S7), mRNA. /FEA=mRNA /GEN=EIF3S7 /PROD=eukaryotic translation initiation factor 3,subunit 7 (zeta, 6667kD) /DB_XREF=gi:4503522 /UG=Hs.55682 eukaryotic translation initiation factor 3, subunit 7 (zeta, 6667kD) /FL=gb:BC000328.1 gb:BC000469.1 gb:U54558.1 gb:NM_003753.1 NM_003753 eukaryotic translation initiation factor 3, subunit D EIF3D 8664 NM_003753 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200006_at NM_007262 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007262.1 /DEF=Homo sapiens RNA-binding protein regulatory subunit (DJ-1), mRNA. /FEA=mRNA /GEN=DJ-1 /PROD=RNA-binding protein regulatory subunit /DB_XREF=gi:6005748 /UG=Hs.10958 RNA-binding protein regulatory subunit /FL=gb:AF021819.1 gb:NM_007262.1 gb:D61380.1 NM_007262 Parkinson disease (autosomal recessive, early onset) 7 PARK7 11315 NM_001123377 /// NM_007262 0006950 // response to stress // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0051583 // dopamine uptake // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200007_at NM_003134 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003134.1 /DEF=Homo sapiens signal recognition particle 14kD (homologous Alu RNA-binding protein) (SRP14), mRNA. /FEA=mRNA /GEN=SRP14 /PROD=signal recognition particle 14kD (homologous AluRNA-binding protein) /DB_XREF=gi:4507210 /UG=Hs.180394 signal recognition particle 14kD (homologous Alu RNA-binding protein) /FL=gb:NM_003134.1 gb:U07857.1 NM_003134 signal recognition particle 14kDa (homologous Alu RNA binding protein) SRP14 6727 NM_003134 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0045900 // negative regulation of translational elongation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // traceable author statement /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // traceable author statement /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0030942 // endoplasmic reticulum signal peptide binding // inferred from electronic annotation 200008_s_at D13988 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D13988.1 /DEF=Human rab GDI mRNA, complete cds. /FEA=mRNA /PROD=human rab GDI /DB_XREF=gi:285974 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2 D13988 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005093 // Rab GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation 200009_at NM_001494 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001494.2 /DEF=Homo sapiens GDP dissociation inhibitor 2 (GDI2), mRNA. /FEA=mRNA /GEN=GDI2 /PROD=GDP dissociation inhibitor 2 /DB_XREF=gi:6598322 /UG=Hs.56845 GDP dissociation inhibitor 2 /FL=gb:BC005145.1 gb:D13988.1 gb:NM_001494.2 NM_001494 GDP dissociation inhibitor 2 GDI2 2665 NM_001115156 /// NM_001494 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005093 // Rab GDP-dissociation inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation 200010_at NM_000975 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000975.1 /DEF=Homo sapiens ribosomal protein L11 (RPL11), mRNA. /FEA=mRNA /GEN=RPL11 /PROD=ribosomal protein L11 /DB_XREF=gi:4506594 /UG=Hs.179943 ribosomal protein L11 /FL=gb:L05092.1 gb:NM_000975.1 NM_000975 ribosomal protein L11 RPL11 6135 NM_000975 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006368 // RNA elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006605 // protein targeting // inferred from mutant phenotype /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype /// 0045449 // regulation of transcription // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0008023 // transcription elongation factor complex // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // traceable author statement /// 0016944 // RNA polymerase II transcription elongation factor activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation 200011_s_at NM_001659 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001659.1 /DEF=Homo sapiens ADP-ribosylation factor 3 (ARF3), mRNA. /FEA=mRNA /GEN=ARF3 /PROD=ADP-ribosylation factor 3 /DB_XREF=gi:4502202 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1 NM_001659 ADP-ribosylation factor 3 ARF3 377 NM_001659 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 200012_x_at NM_000982 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000982.1 /DEF=Homo sapiens ribosomal protein L21 (gene or pseudogene) (RPL21), mRNA. /FEA=mRNA /GEN=RPL21 /PROD=ribosomal protein L21 (gene or pseudogene) /DB_XREF=gi:4506610 /UG=Hs.184108 ribosomal protein L21 /FL=gb:BC001603.1 gb:NM_000982.1 gb:U14967.1 gb:U25789.1 NM_000982 hypothetical LOC653737 /// ribosomal protein L21-like /// ribosomal protein L21 LOC653737 /// LOC729402 /// RPL21 6144 /// 653737 /// 729402 NM_000982 /// NM_001139505 /// XM_001133535 /// XM_001721328 /// XM_001722740 /// XM_001722741 /// XM_001722742 /// XM_001726209 /// XM_929340 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200013_at NM_000986 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000986.1 /DEF=Homo sapiens ribosomal protein L24 (RPL24), mRNA. /FEA=mRNA /GEN=RPL24 /PROD=ribosomal protein L24 /DB_XREF=gi:4506618 /UG=Hs.184582 ribosomal protein L24 /FL=gb:BC000690.1 gb:M94314.1 gb:NM_000986.1 NM_000986 ribosomal protein L24 RPL24 6152 NM_000986 0000027 // ribosomal large subunit assembly and maintenance // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0010458 // exit from mitosis // inferred from electronic annotation /// 0021554 // optic nerve development // inferred from electronic annotation /// 0031290 // retinal ganglion cell axon guidance // inferred from electronic annotation /// 0031575 // G1/S transition checkpoint // inferred from electronic annotation /// 0060041 // retina development in camera-type eye // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200014_s_at NM_004500 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004500.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein C (C1C2) (HNRPC), mRNA. /FEA=mRNA /GEN=HNRPC /PROD=heterogeneous nuclear ribonucleoprotein C(C1C2) /DB_XREF=gi:4758543 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1 NM_004500 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 200015_s_at NM_004404 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004404.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 5 (NEDD5), mRNA. /FEA=mRNA /GEN=NEDD5 /PROD=neural precursor cell expressed, developmentallydown-regulated 5 /DB_XREF=gi:4758157 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1 NM_004404 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_004404 /// NM_006155 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 200016_x_at NM_002136 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002136.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A1 (HNRPA1), mRNA. /FEA=mRNA /GEN=HNRPA1 /PROD=heterogeneous nuclear ribonucleoprotein A1 /DB_XREF=gi:4504444 /UG=Hs.249495 heterogeneous nuclear ribonucleoprotein A1 /FL=gb:NM_002136.1 NM_002136 heterogeneous nuclear ribonucleoprotein A1 HNRNPA1 3178 NM_002136 /// NM_031157 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006405 // RNA export from nucleus // inferred by curator /// 0006405 // RNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051168 // nuclear export // inferred from direct assay /// 0051170 // nuclear import // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003727 // single-stranded RNA binding // inferred by curator /// 0005515 // protein binding // inferred from physical interaction 200017_at NM_002954 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002954.1 /DEF=Homo sapiens ribosomal protein S27a (RPS27A), mRNA. /FEA=mRNA /GEN=RPS27A /PROD=ribosomal protein S27a /DB_XREF=gi:4506712 /UG=Hs.3297 ribosomal protein S27a /FL=gb:BC001392.1 gb:BC005328.1 gb:NM_002954.1 NM_002954 ribosomal protein S27a /// ubiquitin B /// ubiquitin C RPS27A /// UBB /// UBC 6233 /// 7314 /// 7316 NM_001135592 /// NM_002954 /// NM_018955 /// NM_021009 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006464 // protein modification process // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030433 // ER-associated protein catabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042062 // long-term strengthening of neuromuscular junction // traceable author statement /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200018_at NM_001017 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001017.1 /DEF=Homo sapiens ribosomal protein S13 (RPS13), mRNA. /FEA=mRNA /GEN=RPS13 /PROD=ribosomal protein S13 /DB_XREF=gi:4506684 /UG=Hs.165590 ribosomal protein S13 /FL=gb:BC000475.1 gb:L01124.1 gb:NM_001017.1 NM_001017 ribosomal protein S13 RPS13 6207 NM_001017 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded /// 0033119 // negative regulation of RNA splicing // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200019_s_at NM_001997 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001997.1 /DEF=Homo sapiens Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 (FAU), mRNA. /FEA=mRNA /GEN=FAU /PROD=Finkel-Biskis-Reilly murine sarcoma virus(FBR-MuSV) ubiquitously expressed (fox derived); ribosomalprotein S30 /DB_XREF=gi:4503658 /UG=Hs.177415 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); ribosomal protein S30 /FL=gb:NM_001997.1 NM_001997 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed FAU 2197 NM_001997 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006464 // protein modification process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 200020_at NM_007375 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007375.1 /DEF=Homo sapiens TAR DNA binding protein (TARDBP), mRNA. /FEA=mRNA /GEN=TARDBP /PROD=TAR DNA binding protein /DB_XREF=gi:6678270 /UG=Hs.193989 TAR DNA binding protein /FL=gb:AL050265.1 gb:NM_007375.1 gb:U23731.1 NM_007375 TAR DNA binding protein TARDBP 23435 NM_007375 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007067 // mitosis // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // traceable author statement 200021_at NM_005507 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005507.1 /DEF=Homo sapiens cofilin 1 (non-muscle) (CFL1), mRNA. /FEA=mRNA /GEN=CFL1 /PROD=cofilin 1 (non-muscle) /DB_XREF=gi:5031634 /UG=Hs.180370 cofilin 1 (non-muscle) /FL=gb:NM_005507.1 NM_005507 cofilin 1 (non-muscle) CFL1 1072 NM_005507 0000910 // cytokinesis // inferred from electronic annotation /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001842 // neural fold formation // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006928 // cell motion // inferred from electronic annotation /// 0007015 // actin filament organization // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // traceable author statement /// 0030010 // establishment of cell polarity // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200022_at NM_000979 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000979.1 /DEF=Homo sapiens ribosomal protein L18 (RPL18), mRNA. /FEA=mRNA /GEN=RPL18 /PROD=ribosomal protein L18 /DB_XREF=gi:4506606 /UG=Hs.75458 ribosomal protein L18 /FL=gb:BC000374.1 gb:L11566.1 gb:NM_000979.1 NM_000979 ribosomal protein L18 RPL18 6141 NM_000979 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200023_s_at NM_003754 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003754.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) (EIF3S5), mRNA. /FEA=mRNA /GEN=EIF3S5 /PROD=eukaryotic translation initiation factor 3,subunit 5 (epsilon, 47kD) /DB_XREF=gi:4503518 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1 NM_003754 eukaryotic translation initiation factor 3, subunit F EIF3F 8665 NM_003754 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200024_at NM_001009 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001009.1 /DEF=Homo sapiens ribosomal protein S5 (RPS5), mRNA. /FEA=mRNA /GEN=RPS5 /PROD=ribosomal protein S5 /DB_XREF=gi:4506728 /UG=Hs.76194 ribosomal protein S5 /FL=gb:NM_001009.1 gb:U14970.1 NM_001009 ribosomal protein S5 RPS5 6193 NM_001009 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from genetic interaction /// 0006412 // translation // non-traceable author statement /// 0006413 // translational initiation // inferred by curator /// 0006414 // translational elongation // not recorded /// 0006450 // regulation of translational fidelity // inferred from genetic interaction 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200025_s_at NM_000988 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000988.1 /DEF=Homo sapiens ribosomal protein L27 (RPL27), mRNA. /FEA=mRNA /GEN=RPL27 /PROD=ribosomal protein L27 /DB_XREF=gi:4506622 /UG=Hs.111611 ribosomal protein L27 /FL=gb:BC002588.1 gb:L05094.1 gb:L19527.1 gb:NM_000988.1 NM_000988 ribosomal protein L27 RPL27 6155 NM_000988 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement 200026_at NM_000995 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000995.1 /DEF=Homo sapiens ribosomal protein L34 (RPL34), mRNA. /FEA=mRNA /GEN=RPL34 /PROD=ribosomal protein L34 /DB_XREF=gi:4506636 /UG=Hs.250895 ribosomal protein L34 /FL=gb:L38941.1 gb:BC001773.1 gb:NM_000995.1 NM_000995 ribosomal protein L34 RPL34 6164 NM_000995 /// NM_033625 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200027_at NM_004539 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004539.2 /DEF=Homo sapiens asparaginyl-tRNA synthetase (NARS), mRNA. /FEA=mRNA /GEN=NARS /PROD=asparaginyl-tRNA synthetase /DB_XREF=gi:7262387 /UG=Hs.181311 asparaginyl-tRNA synthetase /FL=gb:BC001687.1 gb:D84273.1 gb:NM_004539.2 NM_004539 asparaginyl-tRNA synthetase NARS 4677 NM_004539 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006421 // asparaginyl-tRNA aminoacylation // inferred from electronic annotation /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0004816 // asparagine-tRNA ligase activity // traceable author statement /// 0004816 // asparagine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200028_s_at NM_020151 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_020151.1 /DEF=Homo sapiens GTT1 protein (GTT1), mRNA. /FEA=mRNA /GEN=GTT1 /PROD=GTT1 protein /DB_XREF=gi:9910251 /UG=Hs.283722 GTT1 protein /FL=gb:AF270647.1 gb:NM_020151.1 NM_020151 StAR-related lipid transfer (START) domain containing 7 STARD7 56910 NM_020151 0005739 // mitochondrion // inferred from electronic annotation 200029_at NM_000981 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000981.1 /DEF=Homo sapiens ribosomal protein L19 (RPL19), mRNA. /FEA=mRNA /GEN=RPL19 /PROD=ribosomal protein L19 /DB_XREF=gi:4506608 /UG=Hs.252723 ribosomal protein L19 /FL=gb:BC000530.1 gb:NM_000981.1 NM_000981 ribosomal protein L19 RPL19 6143 NM_000981 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0022625 // cytosolic large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200030_s_at NM_002635 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002635.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 (SLC25A3), nuclear gene encoding mitochondrial protein, transcript variant 1b, mRNA. /FEA=mRNA /GEN=SLC25A3 /PROD=phosphate carrier precursor isoform 1b /DB_XREF=gi:4505774 /UG=Hs.78713 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 /FL=gb:BC000998.1 gb:BC001328.1 gb:BC003504.1 gb:BC004345.1 gb:NM_002635.1 NM_002635 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 SLC25A3 5250 NM_002635 /// NM_005888 /// NM_213611 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015293 // symporter activity // inferred from electronic annotation /// 0015320 // phosphate carrier activity // traceable author statement 200031_s_at NM_001015 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001015.1 /DEF=Homo sapiens ribosomal protein S11 (RPS11), mRNA. /FEA=mRNA /GEN=RPS11 /PROD=ribosomal protein S11 /DB_XREF=gi:4506680 /UG=Hs.182740 ribosomal protein S11 /FL=gb:NM_001015.1 NM_001015 ribosomal protein S11 RPS11 6205 NM_001015 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019843 // rRNA binding // inferred from electronic annotation 200032_s_at NM_000661 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000661.1 /DEF=Homo sapiens ribosomal protein L9 (RPL9), mRNA. /FEA=mRNA /GEN=RPL9 /PROD=ribosomal protein L9 /DB_XREF=gi:4506664 /UG=Hs.157850 ribosomal protein L9 /FL=gb:U09953.1 gb:NM_000661.1 NM_000661 ribosomal protein L9 RPL9 6133 NM_000661 /// NM_001024921 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200033_at NM_004396 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004396.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) (DDX5), mRNA. /FEA=mRNA /GEN=DDX5 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 /DB_XREF=gi:13514826 /UG=Hs.76053 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 5 (RNA helicase, 68kD) /FL=gb:NM_004396.2 NM_004396 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 DDX5 1655 NM_004396 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016049 // cell growth // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0003724 // RNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation 200034_s_at NM_000970 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000970.1 /DEF=Homo sapiens ribosomal protein L6 (RPL6), mRNA. /FEA=mRNA /GEN=RPL6 /PROD=ribosomal protein L6 /DB_XREF=gi:4506656 /UG=Hs.174131 ribosomal protein L6 /FL=gb:BC004138.1 gb:D17554.1 gb:NM_000970.1 gb:AF261087.1 NM_000970 ribosomal protein L6 RPL6 6128 NM_000970 /// NM_001024662 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement 200035_at NM_015343 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015343.1 /DEF=Homo sapiens hypothetical protein (HSA011916), mRNA. /FEA=mRNA /GEN=HSA011916 /PROD=hypothetical protein /DB_XREF=gi:7661721 /UG=Hs.84359 hypothetical protein /FL=gb:NM_015343.1 NM_015343 dullard homolog (Xenopus laevis) DULLARD 23399 NM_001143775 /// NM_015343 0006470 // protein amino acid dephosphorylation // inferred from direct assay /// 0006998 // nuclear envelope organization // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from mutant phenotype /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200036_s_at NM_007104 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007104.2 /DEF=Homo sapiens ribosomal protein L10a (RPL10A), mRNA. /FEA=mRNA /GEN=RPL10A /PROD=ribosomal protein L10a /DB_XREF=gi:6325471 /UG=Hs.252574 ribosomal protein L10a /FL=gb:U12404.1 gb:NM_007104.2 NM_007104 ribosomal protein L10a RPL10A 4736 NM_007104 0006396 // RNA processing // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200037_s_at NM_016587 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016587.1 /DEF=Homo sapiens heterochromatin-like protein 1 (HECH), mRNA. /FEA=mRNA /GEN=HECH /PROD=heterochromatin-like protein 1 /DB_XREF=gi:7705406 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1 NM_016587 chromobox homolog 3 (HP1 gamma homolog, Drosophila) /// similar to chromobox homolog 3 CBX3 /// LOC653972 11335 /// 653972 NM_007276 /// NM_016587 /// XM_938779 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation 0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005701 // polytene chromosome chromocenter // inferred from sequence or structural similarity /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016565 // general transcriptional repressor activity // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction 200038_s_at NM_000985 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000985.1 /DEF=Homo sapiens ribosomal protein L17 (RPL17), mRNA. /FEA=mRNA /GEN=RPL17 /PROD=ribosomal protein L17 /DB_XREF=gi:4506616 /UG=Hs.82202 ribosomal protein L17 /FL=gb:BC000502.1 gb:NM_000985.1 NM_000985 ribosomal protein L17 RPL17 6139 NM_000985 /// NM_001035006 /// XM_001713653 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype 200039_s_at NM_002794 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002794.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 2 (PSMB2), mRNA. /FEA=mRNA /GEN=PSMB2 /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:4506194 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1 NM_002794 proteasome (prosome, macropain) subunit, beta type, 2 PSMB2 5690 NM_002794 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200040_at NM_006559 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006559.1 /DEF=Homo sapiens GAP-associated tyrosine phosphoprotein p62 (Sam68) (SAM68), mRNA. /FEA=mRNA /GEN=SAM68 /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:5730026 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1 NM_006559 KH domain containing, RNA binding, signal transduction associated 1 KHDRBS1 10657 NM_006559 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor linked signal transduction // inferred from direct assay /// 0007166 // cell surface receptor linked signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016481 // negative regulation of transcription // inferred from sequence or structural similarity /// 0016481 // negative regulation of transcription // inferred from electronic annotation /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046831 // regulation of RNA export from nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from sequence or structural similarity /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 200041_s_at NM_004640 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004640.1 /DEF=Homo sapiens HLA-B associated transcript-1 (D6S81E), mRNA. /FEA=mRNA /GEN=D6S81E /PROD=HLA-B associated transcript-1 /DB_XREF=gi:4758111 /UG=Hs.55296 HLA-B associated transcript-1 /FL=gb:BC004350.1 gb:NM_004640.1 NM_004640 HLA-B associated transcript 1 BAT1 7919 NM_004640 /// NM_080598 0000398 // nuclear mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200042_at NM_014306 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014306.1 /DEF=Homo sapiens hypothetical protein (HSPC117), mRNA. /FEA=mRNA /GEN=HSPC117 /PROD=similar to C. elegens hypothetical 55.2 kDprotein F16A11.2 /DB_XREF=gi:7657014 /UG=Hs.10729 hypothetical protein /FL=gb:BC000151.1 gb:BC002970.1 gb:AF161466.1 gb:NM_014306.1 gb:AF155658.1 NM_014306 chromosome 22 open reading frame 28 C22orf28 51493 NM_014306 0007160 // cell-matrix adhesion // non-traceable author statement /// 0034446 // substrate adhesion-dependent cell spreading // non-traceable author statement 0017166 // vinculin binding // inferred from physical interaction 200043_at NM_004450 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004450.1 /DEF=Homo sapiens enhancer of rudimentary (Drosophila) homolog (ERH), mRNA. /FEA=mRNA /GEN=ERH /PROD=enhancer of rudimentary (Drosophila) homolog /DB_XREF=gi:4758301 /UG=Hs.118757 enhancer of rudimentary (Drosophila) homolog /FL=gb:D85758.1 gb:U66871.1 gb:NM_004450.1 NM_004450 enhancer of rudimentary homolog (Drosophila) ERH 2079 NM_004450 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0006213 // pyrimidine nucleoside metabolic process // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200044_at NM_003769 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1 NM_003769 splicing factor, arginine/serine-rich 9 SFRS9 8683 NM_003769 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 200045_at NM_001090 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001090.1 /DEF=Homo sapiens ATP-binding cassette, sub-family F (GCN20), member 1 (ABCF1), mRNA. /FEA=mRNA /GEN=ABCF1 /PROD=ATP-binding cassette, sub-family F, member 1 /DB_XREF=gi:10947134 /UG=Hs.9573 ATP-binding cassette, sub-family F (GCN20), member 1 /FL=gb:NM_001090.1 gb:AF027302.1 NM_001090 ATP-binding cassette, sub-family F (GCN20), member 1 ABCF1 23 NM_001025091 /// NM_001090 0006412 // translation // traceable author statement /// 0006954 // inflammatory response // traceable author statement 0005901 // caveola // inferred from electronic annotation /// 0016600 // flotillin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042626 // ATPase activity, coupled to transmembrane movement of substances // traceable author statement 200046_at NM_001344 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001344.1 /DEF=Homo sapiens defender against cell death 1 (DAD1), mRNA. /FEA=mRNA /GEN=DAD1 /PROD=defender against cell death 1 /DB_XREF=gi:4503252 /UG=Hs.82890 defender against cell death 1 /FL=gb:NM_001344.1 gb:D15057.1 NM_001344 defender against cell death 1 DAD1 1603 NM_001344 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0018279 // protein amino acid N-linked glycosylation via asparagine // inferred by curator 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred by curator /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200047_s_at NM_003403 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003403.2 /DEF=Homo sapiens YY1 transcription factor (YY1), mRNA. /FEA=mRNA /GEN=YY1 /PROD=YY1 transcription factor /DB_XREF=gi:6042207 /UG=Hs.97496 YY1 transcription factor /FL=gb:M77698.1 gb:M76541.1 gb:NM_003403.2 NM_003403 YY1 transcription factor YY1 7528 NM_003403 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0031519 // PcG protein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200048_s_at NM_006694 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006694.1 /DEF=Homo sapiens jumping translocation breakpoint (JTB), mRNA. /FEA=mRNA /GEN=JTB /PROD=jumping translocation breakpoint /DB_XREF=gi:5729888 /UG=Hs.6396 jumping translocation breakpoint /FL=gb:BC000499.1 gb:BC001363.1 gb:BC000996.2 gb:BC001667.1 gb:AB016488.1 gb:AF131797.1 gb:NM_006694.1 gb:AF115850.2 NM_006694 jumping translocation breakpoint JTB 10899 NM_006694 0005624 // membrane fraction // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 200049_at NM_007067 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007067.1 /DEF=Homo sapiens histone acetyltransferase (HBOA), mRNA. /FEA=mRNA /GEN=HBOA /PROD=histone acetyltransferase /DB_XREF=gi:5901961 /UG=Hs.21907 histone acetyltransferase /FL=gb:AF074606.1 gb:AF140360.1 gb:NM_007067.1 NM_007067 MYST histone acetyltransferase 2 MYST2 11143 NM_007067 0006260 // DNA replication // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003700 // transcription factor activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004406 // H3/H4 histone acetyltransferase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016747 // transferase activity, transferring acyl groups other than amino-acyl groups // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200050_at NM_007145 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007145.1 /DEF=Homo sapiens zinc finger protein 146 (ZNF146), mRNA. /FEA=mRNA /GEN=ZNF146 /PROD=zinc finger protein 146 /DB_XREF=gi:6005965 /UG=Hs.301819 zinc finger protein 146 /FL=gb:BC005154.1 gb:NM_007145.1 NM_007145 zinc finger protein 146 ZNF146 7705 NM_001099638 /// NM_001099639 /// NM_007145 0006355 // regulation of transcription, DNA-dependent // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200051_at NM_005146 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005146.1 /DEF=Homo sapiens squamous cell carcinoma antigen recognised by T cells (SART1), mRNA. /FEA=mRNA /GEN=SART1 /PROD=squamous cell carcinoma antigen recognised by Tcells /DB_XREF=gi:10863888 /UG=Hs.288319 squamous cell carcinoma antigen recognised by T cells /FL=gb:NM_005146.1 gb:BC001058.1 gb:AB006198.1 NM_005146 squamous cell carcinoma antigen recognized by T cells SART1 9092 NM_005146 0006397 // mRNA processing // inferred from electronic annotation /// 0007050 // cell cycle arrest // non-traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0008629 // induction of apoptosis by intracellular signals // non-traceable author statement /// 0045585 // positive regulation of cytotoxic T cell differentiation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement 200052_s_at NM_004515 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004515.1 /DEF=Homo sapiens interleukin enhancer binding factor 2, 45kD (ILF2), mRNA. /FEA=mRNA /GEN=ILF2 /PROD=interleukin enhancer binding factor 2, 45kD /DB_XREF=gi:4758601 /UG=Hs.75117 interleukin enhancer binding factor 2, 45kD /FL=gb:BC000382.1 gb:NM_004515.1 gb:U10323.1 NM_004515 interleukin enhancer binding factor 2, 45kDa ILF2 3608 NM_004515 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from direct assay 200053_at NM_004890 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004890.1 /DEF=Homo sapiens sperm associated antigen 7 (SPAG7), mRNA. /FEA=mRNA /GEN=SPAG7 /PROD=sperm associated antigen 7 /DB_XREF=gi:4757715 /UG=Hs.90436 sperm associated antigen 7 /FL=gb:AF047437.1 gb:NM_004890.1 NM_004890 sperm associated antigen 7 SPAG7 9552 NM_004890 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200054_at NM_003904 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003904.1 /DEF=Homo sapiens zinc finger protein 259 (ZNF259), mRNA. /FEA=mRNA /GEN=ZNF259 /PROD=zinc finger protein 259 /DB_XREF=gi:4508020 /UG=Hs.7165 zinc finger protein 259 /FL=gb:BC004256.1 gb:AF019767.1 gb:NM_003904.1 NM_003904 zinc finger protein 259 ZNF259 8882 NM_003904 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200055_at NM_006284 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006284.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD (TAF2H), mRNA. /FEA=mRNA /GEN=TAF2H /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, H, 30kD /DB_XREF=gi:5454105 /UG=Hs.89657 TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD /FL=gb:NM_006284.1 gb:U13991.1 NM_006284 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa TAF10 6881 NM_006284 0006350 // transcription // inferred from electronic annotation /// 0006352 // transcription initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006368 // RNA elongation from RNA polymerase II promoter // not recorded 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005669 // transcription factor TFIID complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003702 // RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200056_s_at NM_006333 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006333.1 /DEF=Homo sapiens nuclear DNA-binding protein (C1D), mRNA. /FEA=mRNA /GEN=C1D /PROD=nuclear DNA-binding protein /DB_XREF=gi:5453582 /UG=Hs.15164 nuclear DNA-binding protein /FL=gb:NM_006333.1 NM_006333 nuclear DNA-binding protein C1D 10438 NM_006333 /// NM_173177 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from electronic annotation 0000178 // exosome (RNase complex) // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0017053 // transcriptional repressor complex // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016922 // ligand-dependent nuclear receptor binding // inferred from electronic annotation 200057_s_at NM_007363 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007363.2 /DEF=Homo sapiens non-POU-domain-containing, octamer-binding (NONO), mRNA. /FEA=mRNA /GEN=NONO /PROD=non-Pou domain-containing octamer (ATGCAAAT)binding protein /DB_XREF=gi:7657382 /UG=Hs.172207 non-POU-domain-containing, octamer-binding /FL=gb:NM_007363.2 NM_007363 non-POU domain containing, octamer-binding NONO 4841 NM_007363 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 200058_s_at BC001417 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001417.1 /DEF=Homo sapiens, Similar to U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family), clone MGC:2580, mRNA, complete cds. /FEA=mRNA /PROD=Similar to U5 snRNP-specific protein, 200 kDa(DEXH RNA helicase family) /DB_XREF=gi:12655128 /UG=Hs.246112 KIAA0788 protein /FL=gb:BC001417.1 gb:AF119874.1 BC001417 small nuclear ribonucleoprotein 200kDa (U5) SNRNP200 23020 NM_014014 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005682 // snRNP U5 // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred by curator /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 200059_s_at BC001360 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001360.1 /DEF=Homo sapiens, ras homolog gene family, member A, clone MGC:2330, mRNA, complete cds. /FEA=mRNA /PROD=ras homolog gene family, member A /DB_XREF=gi:12655024 /UG=Hs.77273 ras homolog gene family, member A /FL=gb:NM_001664.1 gb:BC001360.1 gb:L25080.1 BC001360 ras homolog gene family, member A RHOA 387 NM_001664 0000902 // cell morphogenesis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042346 // positive regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from expression pattern /// 0043149 // stress fiber formation // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptosis // inferred from electronic annotation /// 0045665 // negative regulation of neuron differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 200060_s_at BC001659 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001659.1 /DEF=Homo sapiens, RNA-binding protein S1, serine-rich domain, clone MGC:1125, mRNA, complete cds. /FEA=mRNA /PROD=RNA-binding protein S1, serine-rich domain /DB_XREF=gi:12804496 /UG=Hs.75104 RNA-binding protein S1, serine-rich domain /FL=gb:BC001659.1 gb:BC001838.1 BC001659 RNA binding protein S1, serine-rich domain RNPS1 10921 NM_006711 /// NM_080594 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // non-traceable author statement /// 0006350 // transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200061_s_at BC000523 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000523.1 /DEF=Homo sapiens, Similar to ribosomal protein S24, clone MGC:8595, mRNA, complete cds. /FEA=mRNA /PROD=Similar to ribosomal protein S24 /DB_XREF=gi:12653502 /UG=Hs.180450 ribosomal protein S24 /FL=gb:BC000523.1 gb:BC003149.1 BC000523 ribosomal protein S24 RPS24 6229 NM_001026 /// NM_001142282 /// NM_001142283 /// NM_001142284 /// NM_001142285 /// NM_033022 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0015935 // small ribosomal subunit // inferred from sequence or structural similarity /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0031369 // translation initiation factor binding // inferred from sequence or structural similarity 200062_s_at L05095 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:L05095.1 /DEF=Homo sapiens ribosomal protein L30 mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L30 /DB_XREF=gi:388034 /UG=Hs.111222 ribosomal protein L30 /FL=gb:L05095.1 gb:NM_000989.1 L05095 ribosomal protein L30 RPL30 6156 NM_000989 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200063_s_at BC002398 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002398.1 /DEF=Homo sapiens, nucleophosmin (nucleolar phosphoprotein B23, numatrin), clone MGC:8463, mRNA, complete cds. /FEA=mRNA /PROD=nucleophosmin (nucleolar phosphoprotein B23,numatrin) /DB_XREF=gi:12803184 /UG=Hs.9614 nucleophosmin (nucleolar phosphoprotein B23, numatrin) /FL=gb:NM_002520.1 gb:BC002398.1 gb:BC003670.1 gb:M23613.1 gb:M26697.1 gb:M28699.1 BC002398 nucleophosmin (nucleolar phosphoprotein B23, numatrin) NPM1 4869 NM_001037738 /// NM_002520 /// NM_199185 0006334 // nucleosome assembly // inferred from direct assay /// 0006886 // intracellular protein transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // traceable author statement /// 0006916 // anti-apoptosis // non-traceable author statement /// 0006950 // response to stress // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from sequence or structural similarity /// 0007165 // signal transduction // non-traceable author statement /// 0007569 // cell aging // inferred from mutant phenotype /// 0007569 // cell aging // inferred from sequence or structural similarity /// 0008104 // protein localization // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0010826 // negative regulation of centrosome duplication // inferred from mutant phenotype /// 0042255 // ribosome assembly // traceable author statement /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0031616 // spindle pole centrosome // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0030957 // Tat protein binding // inferred from direct assay /// 0042393 // histone binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from mutant phenotype /// 0051059 // NF-kappaB binding // inferred from direct assay /// 0051059 // NF-kappaB binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity 200064_at AF275719 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF275719.1 /DEF=Homo sapiens isolate Liv chaperone protein HSP90 beta (HSP90BETA) mRNA, complete cds. /FEA=mRNA /GEN=HSP90BETA /PROD=chaperone protein HSP90 beta /DB_XREF=gi:9082288 /UG=Hs.74335 heat shock 90kD protein 1, beta /FL=gb:BC004928.1 gb:M16660.1 gb:NM_007355.1 gb:AF275719.1 AF275719 heat shock protein 90kDa alpha (cytosolic), class B member 1 HSP90AB1 3326 NM_007355 0001890 // placenta development // inferred from electronic annotation /// 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // non-traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from sequence or structural similarity 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0030235 // nitric-oxide synthase regulator activity // inferred from sequence or structural similarity /// 0030911 // TPR domain binding // inferred from sequence or structural similarity /// 0051082 // unfolded protein binding // inferred from electronic annotation 200065_s_at AF052179 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF052179.1 /DEF=Homo sapiens clone 24537 ADP-ribosylation factor 1 mRNA, complete cds. /FEA=mRNA /PROD=ADP-ribosylation factor 1 /DB_XREF=gi:3360490 /UG=Hs.74571 ADP-ribosylation factor 1 /FL=gb:M84326.1 gb:M36340.1 gb:AF055002.1 gb:AF052179.1 gb:NM_001658.2 AF052179 ADP-ribosylation factor 1 ARF1 375 NM_001024226 /// NM_001024227 /// NM_001024228 /// NM_001658 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // not recorded /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200066_at AF182645 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF182645.1 /DEF=Homo sapiens chondrosarcoma-associated protein 2 (CSA2) mRNA, complete cds. /FEA=mRNA /GEN=CSA2 /PROD=chondrosarcoma-associated protein 2 /DB_XREF=gi:5901877 /UG=Hs.8024 IK cytokine, down-regulator of HLA II /FL=gb:NM_006083.2 gb:AF182645.1 AF182645 IK cytokine, down-regulator of HLA II IK 3550 NM_006083 0006955 // immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 200067_x_at AL078596 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL078596 /DEF=Human DNA sequence from clone RP3-429G5 on chromosome 6q21-22.1. Contains the NR2E1 gene for nuclear receptor 2E1 (tailless, TLL, TLX, XTLL), the 3 end of the SNX3 gene for sorting nexin 3, ESTs, STSs, GSSs and four predicted CpG islands /FEA=mRNA_2 /DB_XREF=gi:6010168 /UG=Hs.12102 sorting nexin 3 /FL=gb:AF062483.1 gb:AF034546.1 gb:NM_003795.1 AL078596 sorting nexin 3 SNX3 8724 NM_003795 0006810 // transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation 200068_s_at M94859 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M94859.1 /DEF=Human calnexin mRNA, complete cds. /FEA=mRNA /PROD=calnexin /DB_XREF=gi:179831 /UG=Hs.155560 calnexin /FL=gb:NM_001746.1 gb:BC003552.1 gb:M94859.1 gb:M98452.1 gb:L10284.1 gb:L18887.1 M94859 calnexin CANX 821 NM_001024649 /// NM_001746 0006457 // protein folding // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005529 // sugar binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // non-traceable author statement 200069_at AI656011 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI656011 /FEA=EST /DB_XREF=gi:4739990 /DB_XREF=est:tt42e08.x1 /CLONE=IMAGE:2243462 /UG=Hs.116875 KIAA0156 gene product /FL=gb:AB020880.1 gb:NM_014706.1 gb:D63879.1 AI656011 squamous cell carcinoma antigen recognized by T cells 3 SART3 9733 NM_014706 0006396 // RNA processing // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200070_at BC001393 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001393.1 /DEF=Homo sapiens, hypothetical protein, clone MGC:782, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein /DB_XREF=gi:12655084 /UG=Hs.4973 hypothetical protein /FL=gb:BC001393.1 BC001393 chromosome 2 open reading frame 24 C2orf24 27013 NM_015680 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200071_at BF224259 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF224259 /FEA=EST /DB_XREF=gi:11131523 /DB_XREF=est:7q85c09.x1 /CLONE=IMAGE:3705208 /UG=Hs.79968 splicing factor 30, survival of motor neuron-related /FL=gb:AF083385.1 gb:AF107463.1 gb:NM_005871.1 BF224259 survival motor neuron domain containing 1 SMNDC1 10285 NM_005871 0000245 // spliceosome assembly // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200072_s_at AF061832 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF061832.1 /DEF=Homo sapiens M4 protein deletion mutant mRNA, complete cds. /FEA=mRNA /PROD=M4 protein deletion mutant /DB_XREF=gi:3126877 /UG=Hs.79024 heterogeneous nuclear ribonucleoprotein M /FL=gb:AF061832.1 AF061832 heterogeneous nuclear ribonucleoprotein M HNRNPM 4670 NM_005968 /// NM_031203 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from physical interaction 200073_s_at M94630 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M94630.1 /DEF=Homo sapiens hnRNP-C like protein mRNA, complete cds. /FEA=mRNA /PROD=DNA-binding protein /DB_XREF=gi:181913 /UG=Hs.303627 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein 1, 37kD) /FL=gb:M94630.1 M94630 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) HNRNPD 3184 NM_001003810 /// NM_002138 /// NM_031369 /// NM_031370 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0006402 // mRNA catabolic process // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // non-traceable author statement /// 0042162 // telomeric DNA binding // inferred from direct assay 200074_s_at U16738 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U16738.1 /DEF=Homo sapiens CAG-isl 7 mRNA, complete cds. /FEA=mRNA /PROD=CAG-isl 7 /DB_XREF=gi:608516 /UG=Hs.738 ribosomal protein L14 /FL=gb:U16738.1 U16738 ribosomal protein L14 /// ribosomal protein L14-like RPL14 /// RPL14L 144581 /// 9045 NM_001034996 /// NM_003973 /// XR_017790 /// XR_041286 /// XR_041287 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200075_s_at BC006249 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC006249.1 /DEF=Homo sapiens, guanylate kinase 1, clone MGC:10618, mRNA, complete cds. /FEA=mRNA /PROD=guanylate kinase 1 /DB_XREF=gi:13623296 /FL=gb:BC006249.1 BC006249 guanylate kinase 1 GUK1 2987 NM_000858 0006163 // purine nucleotide metabolic process // inferred from direct assay /// 0006163 // purine nucleotide metabolic process // inferred from electronic annotation 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004385 // guanylate kinase activity // inferred from direct assay /// 0004385 // guanylate kinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019206 // nucleoside kinase activity // not recorded 200076_s_at BC006479 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC006479.1 /DEF=Homo sapiens, hypothetical protein MGC2749, clone MGC:4376, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein MGC2749 /DB_XREF=gi:13623702 /FL=gb:BC006479.1 BC006479 chromosome 19 open reading frame 50 C19orf50 79036 NM_024069 0005515 // protein binding // inferred from physical interaction 200077_s_at D87914 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D87914.1 /DEF=Human mRNA for ornithine decarboxylase antizyme, complete cds. /FEA=mRNA /GEN=hAZ-brain /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:1590807 /FL=gb:D87914.1 D87914 ornithine decarboxylase antizyme 1 OAZ1 4946 NM_004152 0006596 // polyamine biosynthetic process // traceable author statement 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // traceable author statement /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 200078_s_at BC005876 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC005876.1 /DEF=Homo sapiens, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD, clone MGC:4498, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 21kD /DB_XREF=gi:13543437 /FL=gb:BC005876.1 BC005876 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b ATP6V0B 533 NM_001039457 /// NM_004047 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation 0005768 // endosome // inferred from electronic annotation /// 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation 200079_s_at AF285758 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF285758.1 /DEF=Homo sapiens lysyl-tRNA synthetase mRNA, complete cds; nuclear gene for mitochondrial product; alternatively spliced. /FEA=CDS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:11095908 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:AF285758.1 AF285758 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0006430 // lysyl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // non-traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200080_s_at AI955655 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI955655 /FEA=EST /DB_XREF=gi:5747965 /DB_XREF=est:wt36f03.x1 /CLONE=IMAGE:2509565 /UG=Hs.181307 H3 histone, family 3A AI955655 H3 histone, family 3A /// H3 histone, family 3B (H3.3B) /// H3 histone, family 3A pseudogene H3F3A /// H3F3B /// LOC440926 3020 /// 3021 /// 440926 NM_002107 /// NM_005324 /// NR_002315 /// XR_042136 /// XR_042137 /// XR_042155 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 200081_s_at BE741754 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE741754 /FEA=EST /DB_XREF=gi:10155746 /DB_XREF=est:601595220F1 /CLONE=IMAGE:3949109 /UG=Hs.241507 ribosomal protein S6 BE741754 ribosomal protein S6 RPS6 6194 NM_001010 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded /// 0031929 // TOR signaling pathway // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200082_s_at AI805587 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI805587 /FEA=EST /DB_XREF=gi:5392153 /DB_XREF=est:tx97a02.x1 /CLONE=IMAGE:2277482 /UG=Hs.301547 ribosomal protein S7 AI805587 similar to ribosomal protein S7 /// ribosomal protein S7 LOC644315 /// RPS7 6201 /// 644315 NM_001011 /// XR_015900 /// XR_017529 /// XR_038829 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200083_at AA621731 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA621731 /FEA=EST /DB_XREF=gi:2525670 /DB_XREF=est:af54h05.s1 /CLONE=IMAGE:1035513 /UG=Hs.12064 ubiquitin specific protease 22 AA621731 ubiquitin specific peptidase 22 USP22 23326 NM_015276 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0009790 // embryonic development // non-traceable author statement /// 0016578 // histone deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0045941 // positive regulation of transcription // inferred from mutant phenotype 0000124 // SAGA complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from direct assay /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0010485 // H4 histone acetyltransferase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200084_at BE748698 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE748698 /FEA=EST /DB_XREF=gi:10162690 /DB_XREF=est:601571740T1 /CLONE=IMAGE:3838712 /UG=Hs.78050 small acidic protein BE748698 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 200085_s_at NM_007108 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:NM_007108.1 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) (TCEB2), mRNA. /FEA=CDS /GEN=TCEB2 /PROD=elongin B /DB_XREF=gi:6005889 /UG=Hs.172772 transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B) /FL=gb:NM_007108.1 gb:L42856.1 NM_007108 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) TCEB2 6923 NM_007108 /// NM_207013 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006368 // RNA elongation from RNA polymerase II promoter // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement 200086_s_at AA854966 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA854966 /FEA=EST /DB_XREF=gi:2942504 /DB_XREF=est:aj70d12.s1 /CLONE=IMAGE:1401815 /UG=Hs.113205 cytochrome c oxidase subunit IV AA854966 cytochrome c oxidase subunit IV isoform 1 COX4I1 1327 NM_001861 0006091 // generation of precursor metabolites and energy // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200087_s_at AK024976 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK024976.1 /DEF=Homo sapiens cDNA: FLJ21323 fis, clone COL02374. /FEA=mRNA /DB_XREF=gi:10437405 /UG=Hs.75914 Homo sapiens cDNA: FLJ21323 fis, clone COL02374 AK024976 transmembrane emp24 domain trafficking protein 2 TMED2 10959 NM_006815 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from sequence or structural similarity /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from sequence or structural similarity /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 200088_x_at AK026491 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK026491.1 /DEF=Homo sapiens cDNA: FLJ22838 fis, clone KAIA4494, highly similar to HUML12A Human ribosomal protein L12 mRNA. /FEA=mRNA /DB_XREF=gi:10439364 /UG=Hs.182979 ribosomal protein L12 AK026491 ribosomal protein L12 RPL12 6136 NM_000976 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200089_s_at AI953886 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI953886 /FEA=EST /DB_XREF=gi:5746196 /DB_XREF=est:wx70g02.x1 /CLONE=IMAGE:2549042 /UG=Hs.286 ribosomal protein L4 AI953886 ribosomal protein L4 RPL4 6124 NM_000968 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 200090_at BG168896 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG168896 /FEA=EST /DB_XREF=gi:12675599 /DB_XREF=est:602320235F1 /CLONE=IMAGE:4415240 /UG=Hs.138381 farnesyltransferase, CAAX box, alpha BG168896 farnesyltransferase, CAAX box, alpha FNTA 2339 NM_001018676 /// NM_001018677 /// NM_002027 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0018346 // protein amino acid prenylation // inferred from electronic annotation /// 0018347 // protein amino acid farnesylation // traceable author statement /// 0018348 // protein amino acid geranylgeranylation // traceable author statement /// 0045213 // neurotransmitter receptor metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // not recorded 0004659 // prenyltransferase activity // inferred from electronic annotation /// 0004660 // protein farnesyltransferase activity // traceable author statement /// 0004660 // protein farnesyltransferase activity // inferred from electronic annotation /// 0004661 // protein geranylgeranyltransferase activity // traceable author statement /// 0004662 // CAAX-protein geranylgeranyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008318 // protein prenyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030548 // acetylcholine receptor regulator activity // inferred from electronic annotation 200091_s_at AA888388 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA888388 /FEA=EST /DB_XREF=gi:3004063 /DB_XREF=est:nw79f03.s1 /CLONE=IMAGE:1252829 /UG=Hs.113029 ribosomal protein S25 AA888388 ribosomal protein S25 RPS25 6230 NM_001028 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from direct assay /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200092_s_at BF216701 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF216701 /FEA=EST /DB_XREF=gi:11110287 /DB_XREF=est:601884615F1 /CLONE=IMAGE:4103235 /UG=Hs.179779 ribosomal protein L37 BF216701 ribosomal protein L37 RPL37 6167 NM_000997 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200093_s_at N32864 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N32864 /FEA=EST /DB_XREF=gi:1153263 /DB_XREF=est:yw88d08.s1 /CLONE=IMAGE:259311 /UG=Hs.256697 histidine triad nucleotide-binding protein N32864 histidine triad nucleotide binding protein 1 HINT1 3094 NM_005340 /// NR_024610 /// NR_024611 0007165 // signal transduction // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 200094_s_at AI004246 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI004246 /FEA=EST /DB_XREF=gi:3213756 /DB_XREF=est:ou03g06.x1 /CLONE=IMAGE:1625242 /UG=Hs.75309 eukaryotic translation elongation factor 2 AI004246 eukaryotic translation elongation factor 2 EEF2 1938 NM_001961 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200095_x_at AA320764 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA320764 /FEA=EST /DB_XREF=gi:1973113 /DB_XREF=est:EST23183 /UG=Hs.76230 ribosomal protein S10 AA320764 ribosomal protein S10 RPS10 6204 NM_001014 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200096_s_at AI862255 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI862255 /FEA=EST /DB_XREF=gi:5526362 /DB_XREF=est:tb77d10.x1 /CLONE=IMAGE:2060371 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD AI862255 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 200097_s_at AI701949 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI701949 /FEA=EST /DB_XREF=gi:4989849 /DB_XREF=est:tq09c07.x1 /CLONE=IMAGE:2208300 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K AI701949 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200098_s_at T33068 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:T33068 /FEA=EST /DB_XREF=gi:615166 /DB_XREF=est:EST56576 /UG=Hs.7101 anaphase-promoting complex subunit 5 T33068 anaphase promoting complex subunit 5 ANAPC5 51433 NM_001137559 /// NM_016237 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000090 // mitotic anaphase // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005654 // nucleoplasm // not recorded /// 0005680 // anaphase-promoting complex // traceable author statement /// 0005829 // cytosol // not recorded 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation 200099_s_at AL356115 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL356115 /DEF=Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands /FEA=CDS_1 /DB_XREF=gi:9795038 /UG=Hs.307132 Human DNA sequence from clone RP11-486O22 on chromosome 10 Contains the 3part of a gene for KIAA1128 protein, a novel pseudogene, a gene for protein similar to RPS3A (ribosomal protein S3A), ESTs, STSs, GSSs and CpG islands AL356115 ribosomal protein S3A RPS3A 6189 NM_001006 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006917 // induction of apoptosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity 200593_s_at BC003621 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003621.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A), clone MGC:1992, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:13177672 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1 BC003621 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200594_x_at NM_004501 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004501.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRPU), mRNA. /FEA=mRNA /GEN=HNRPU /PROD=heterogeneous nuclear ribonucleoprotein U(scaffold attachment factor A) /DB_XREF=gi:4758545 /UG=Hs.103804 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) /FL=gb:BC003367.1 gb:BC003621.1 gb:NM_004501.1 NM_004501 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) HNRNPU 3192 NM_004501 /// NM_031844 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200595_s_at NM_003750 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003750.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) (EIF3S10), mRNA. /FEA=mRNA /GEN=EIF3S10 /PROD=eukaryotic translation initiation factor 3,subunit 10 (theta, 150170kD) /DB_XREF=gi:4503508 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 NM_003750 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 200596_s_at BE614908 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE614908 /FEA=EST /DB_XREF=gi:9896507 /DB_XREF=est:601280348F1 /CLONE=IMAGE:3622499 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 BE614908 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 200597_at AI123320 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI123320 /FEA=EST /DB_XREF=gi:3539086 /DB_XREF=est:qa48a10.x1 /CLONE=IMAGE:1689978 /UG=Hs.198899 eukaryotic translation initiation factor 3, subunit 10 (theta, 150170kD) /FL=gb:D50929.1 gb:U58046.1 gb:U78311.1 gb:NM_003750.1 AI123320 eukaryotic translation initiation factor 3, subunit A EIF3A 8661 NM_003750 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005198 // structural molecule activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 200598_s_at AI582238 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI582238 /FEA=EST /DB_XREF=gi:4568135 /DB_XREF=est:tq65c10.x1 /CLONE=IMAGE:2213682 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1 AI582238 heat shock protein 90kDa beta (Grp94), member 1 HSP90B1 7184 NM_003299 0001666 // response to hypoxia // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005792 // microsome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200599_s_at NM_003299 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003299.1 /DEF=Homo sapiens tumor rejection antigen (gp96) 1 (TRA1), mRNA. /FEA=mRNA /GEN=TRA1 /PROD=tumor rejection antigen (gp96) 1 /DB_XREF=gi:4507676 /UG=Hs.82689 tumor rejection antigen (gp96) 1 /FL=gb:NM_003299.1 NM_003299 heat shock protein 90kDa beta (Grp94), member 1 HSP90B1 7184 NM_003299 0001666 // response to hypoxia // inferred from direct assay /// 0006457 // protein folding // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0015031 // protein transport // non-traceable author statement /// 0051208 // sequestering of calcium ion // non-traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0005792 // microsome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0046790 // virion binding // inferred from physical interaction /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200600_at NM_002444 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002444.1 /DEF=Homo sapiens moesin (MSN), mRNA. /FEA=mRNA /GEN=MSN /PROD=moesin /DB_XREF=gi:4505256 /UG=Hs.170328 moesin /FL=gb:M69066.1 gb:NM_002444.1 NM_002444 moesin MSN 4478 NM_002444 0006928 // cell motion // traceable author statement /// 0007159 // leukocyte adhesion // inferred from expression pattern /// 0022614 // membrane to membrane docking // inferred from expression pattern /// 0050900 // leukocyte migration // inferred from expression pattern 0001931 // uropod // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005902 // microvillus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019898 // extrinsic to membrane // inferred from electronic annotation /// 0030175 // filopodium // inferred from direct assay /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0005102 // receptor binding // inferred from physical interaction /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0050839 // cell adhesion molecule binding // inferred from physical interaction 200601_at U48734 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U48734.1 /DEF=Human non-muscle alpha-actinin mRNA, complete cds. /FEA=mRNA /PROD=alpha actinin /DB_XREF=gi:3157975 /UG=Hs.182485 actinin, alpha 4 /FL=gb:NM_004924.2 gb:BC005033.1 gb:D89980.1 gb:U48734.1 U48734 actinin, alpha 4 ACTN4 81 NM_004924 0001666 // response to hypoxia // inferred from electronic annotation /// 0032417 // positive regulation of sodium:hydrogen antiporter activity // non-traceable author statement /// 0042981 // regulation of apoptosis // non-traceable author statement /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0048549 // positive regulation of pinocytosis // inferred from electronic annotation /// 0051017 // actin filament bundle formation // inferred from electronic annotation /// 0051271 // negative regulation of cell motion // inferred from electronic annotation /// 0051272 // positive regulation of cell motion // inferred from direct assay /// 0051272 // positive regulation of cell motion // inferred from mutant phenotype /// 0051272 // positive regulation of cell motion // inferred from electronic annotation 0001725 // stress fiber // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030863 // cortical cytoskeleton // inferred from electronic annotation /// 0031143 // pseudopodium // traceable author statement /// 0031143 // pseudopodium // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001882 // nucleoside binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005178 // integrin binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // traceable author statement /// 0047485 // protein N-terminus binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from electronic annotation 200602_at NM_000484 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000484.1 /DEF=Homo sapiens amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) (APP), mRNA. /FEA=mRNA /GEN=APP /PROD=amyloid beta (A4) precursor protein (proteasenexin-II, Alzheimer disease) /DB_XREF=gi:4502166 /UG=Hs.177486 amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease) /FL=gb:NM_000484.1 NM_000484 amyloid beta (A4) precursor protein APP 351 NM_000484 /// NM_001136016 /// NM_001136129 /// NM_001136130 /// NM_001136131 /// NM_201413 /// NM_201414 0006878 // cellular copper ion homeostasis // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007219 // Notch signaling pathway // inferred from electronic annotation /// 0008219 // cell death // inferred from electronic annotation /// 0050905 // neuromuscular process // non-traceable author statement 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // not recorded 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from direct assay /// 0004867 // serine-type endopeptidase inhibitor activity // non-traceable author statement /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0033130 // acetylcholine receptor binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200603_at AL050038 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL050038.1 /DEF=Homo sapiens mRNA; cDNA DKFZp566J0124 (from clone DKFZp566J0124). /FEA=mRNA /DB_XREF=gi:4884279 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 AL050038 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) PRKAR1A 5573 NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein amino acid phosphorylation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0009755 // hormone-mediated signaling // not recorded 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation 200604_s_at M18468 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M18468.1 /DEF=Human cAMP-dependent protein kinase regulatory subunit type I (PRKAR1A) mRNA, complete cds. /FEA=mRNA /GEN=PRKAR1A /PROD=cAMP-dependent protein kinase regulatory subunittype 1 /DB_XREF=gi:1526988 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 M18468 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) PRKAR1A 5573 NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein amino acid phosphorylation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0009755 // hormone-mediated signaling // not recorded 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation 200605_s_at NM_002734 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002734.1 /DEF=Homo sapiens protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), mRNA. /FEA=mRNA /GEN=PRKAR1A /PROD=protein kinase, cAMP-dependent, regulatory, typeI, alpha /DB_XREF=gi:4506062 /UG=Hs.183037 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) /FL=gb:M18468.1 gb:M33336.1 gb:NM_002734.1 NM_002734 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) PRKAR1A 5573 NM_002734 /// NM_212471 /// NM_212472 0001707 // mesoderm formation // inferred from electronic annotation /// 0001932 // regulation of protein amino acid phosphorylation // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0009755 // hormone-mediated signaling // not recorded 0005952 // cAMP-dependent protein kinase complex // inferred from electronic annotation /// 0031594 // neuromuscular junction // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0030552 // cAMP binding // inferred from electronic annotation 200606_at NM_004415 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004415.1 /DEF=Homo sapiens desmoplakin (DPI, DPII) (DSP), mRNA. /FEA=mRNA /GEN=DSP /PROD=desmoplakin (DPI, DPII) /DB_XREF=gi:4758199 /UG=Hs.74316 desmoplakin (DPI, DPII) /FL=gb:M77830.3 gb:NM_004415.1 NM_004415 desmoplakin DSP 1832 NM_001008844 /// NM_004415 0008544 // epidermis development // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay 0001533 // cornified envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from direct assay /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from direct assay 200607_s_at BG289967 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG289967 /FEA=EST /DB_XREF=gi:13046289 /DB_XREF=est:602381386F1 /CLONE=IMAGE:4499085 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1 BG289967 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200608_s_at NM_006265 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006265.1 /DEF=Homo sapiens RAD21 (S. pombe) homolog (RAD21), mRNA. /FEA=mRNA /GEN=RAD21 /PROD=RAD21 (S. pombe) homolog /DB_XREF=gi:5453993 /UG=Hs.81848 RAD21 (S. pombe) homolog /FL=gb:D38551.1 gb:NM_006265.1 NM_006265 RAD21 homolog (S. pombe) RAD21 5885 NM_006265 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007131 // reciprocal meiotic recombination // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0000228 // nuclear chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200609_s_at NM_017491 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_017491.1 /DEF=Homo sapiens WD repeat domain 1 (WDR1), transcript variant 1, mRNA. /FEA=mRNA /GEN=WDR1 /PROD=WD repeat-containing protein 1, isoform 1 /DB_XREF=gi:9257256 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1 NM_017491 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 0007605 // sensory perception of sound // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement 200610_s_at NM_005381 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005381.1 /DEF=Homo sapiens nucleolin (NCL), mRNA. /FEA=mRNA /GEN=NCL /PROD=nucleolin /DB_XREF=gi:4885510 /UG=Hs.79110 nucleolin /FL=gb:NM_005381.1 NM_005381 nucleolin NCL 4691 NM_005381 0001525 // angiogenesis // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005938 // cell cortex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // inferred from direct assay 200611_s_at AB010427 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB010427.2 /DEF=Homo sapiens mRNA for NORI-1, complete cds. /FEA=mRNA /PROD=NORI-1 /DB_XREF=gi:5103672 /UG=Hs.85100 WD repeat domain 1 /FL=gb:BC000201.1 gb:BC002489.1 gb:AF020056.1 gb:AB010427.2 gb:NM_017491.1 AB010427 WD repeat domain 1 WDR1 9948 NM_005112 /// NM_017491 0007605 // sensory perception of sound // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement 200612_s_at NM_001282 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001282.1 /DEF=Homo sapiens adaptor-related protein complex 2, beta 1 subunit (AP2B1), mRNA. /FEA=mRNA /GEN=AP2B1 /PROD=adaptor-related protein complex 2, beta 1subunit /DB_XREF=gi:4557468 /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1 NM_001282 adaptor-related protein complex 2, beta 1 subunit AP2B1 163 NM_001030006 /// NM_001282 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // not recorded 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 200613_at NM_004068 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004068.1 /DEF=Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), mRNA. /FEA=mRNA /GEN=AP2M1 /PROD=adaptor-related protein complex 2, mu 1 subunit /DB_XREF=gi:4757993 /UG=Hs.152936 adaptor-related protein complex 2, mu 1 subunit /FL=gb:U36188.1 gb:BC004996.1 gb:D63475.1 gb:NM_004068.1 NM_004068 adaptor-related protein complex 2, mu 1 subunit AP2M1 1173 NM_001025205 /// NM_004068 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // not recorded 0005739 // mitochondrion // inferred from electronic annotation /// 0005778 // peroxisomal membrane // not recorded /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation 200614_at NM_004859 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004859.1 /DEF=Homo sapiens clathrin, heavy polypeptide (Hc) (CLTC), mRNA. /FEA=mRNA /GEN=CLTC /PROD=clathrin heavy chain /DB_XREF=gi:4758011 /UG=Hs.178710 clathrin, heavy polypeptide (Hc) /FL=gb:D21260.1 gb:NM_004859.1 NM_004859 clathrin, heavy chain (Hc) CLTC 1213 NM_004859 0006886 // intracellular protein transport // non-traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005198 // structural molecule activity // non-traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200615_s_at AL567295 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL567295 /FEA=EST /DB_XREF=gi:12920509 /DB_XREF=est:AL567295 /CLONE=CS0DF027YO06 (3 prime) /UG=Hs.74626 adaptor-related protein complex 2, beta 1 subunit /FL=gb:M34175.1 gb:NM_001282.1 AL567295 adaptor-related protein complex 2, beta 1 subunit AP2B1 163 NM_001030006 /// NM_001282 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0050690 // regulation of defense response to virus by virus // not recorded 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030131 // clathrin adaptor complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 200616_s_at BC000371 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000371.1 /DEF=Homo sapiens, KIAA0152 gene product, clone MGC:8341, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0152 gene product /DB_XREF=gi:12653206 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1 BC000371 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200617_at NM_014730 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014730.1 /DEF=Homo sapiens KIAA0152 gene product (KIAA0152), mRNA. /FEA=mRNA /GEN=KIAA0152 /PROD=KIAA0152 gene product /DB_XREF=gi:7661947 /UG=Hs.181418 KIAA0152 gene product /FL=gb:BC000371.1 gb:D63486.1 gb:NM_014730.1 NM_014730 malectin MLEC 9761 NM_014730 0005975 // carbohydrate metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200618_at NM_006148 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006148.1 /DEF=Homo sapiens LIM and SH3 protein 1 (LASP1), mRNA. /FEA=mRNA /GEN=LASP1 /PROD=LIM and SH3 protein 1 /DB_XREF=gi:5453709 /UG=Hs.75080 LIM and SH3 protein 1 /FL=gb:NM_006148.1 NM_006148 LIM and SH3 protein 1 LASP1 3927 NM_006148 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from sequence or structural similarity /// 0006811 // ion transport // inferred from electronic annotation /// 0030865 // cortical cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from sequence or structural similarity /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0015075 // ion transmembrane transporter activity // inferred from sequence or structural similarity /// 0015075 // ion transmembrane transporter activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 200619_at NM_006842 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006842.1 /DEF=Homo sapiens splicing factor 3b, subunit 2, 145kD (SF3B2), mRNA. /FEA=mRNA /GEN=SF3B2 /PROD=splicing factor 3b, subunit 2, 145kD /DB_XREF=gi:5803154 /UG=Hs.75916 splicing factor 3b, subunit 2, 145kD /FL=gb:U41371.1 gb:NM_006842.1 NM_006842 splicing factor 3b, subunit 2, 145kDa SF3B2 10992 NM_006842 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005681 // spliceosome // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200620_at NM_004872 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004872.1 /DEF=Homo sapiens chromosome 1 open reading frame 8 (C1ORF8), mRNA. /FEA=mRNA /GEN=C1ORF8 /PROD=chromosome 1 open reading frame 8 /DB_XREF=gi:4758571 /UG=Hs.11441 chromosome 1 open reading frame 8 /FL=gb:BC003106.1 gb:AF290615.1 gb:AF047439.1 gb:NM_004872.1 NM_004872 transmembrane protein 59 TMEM59 9528 NM_004872 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200621_at NM_004078 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004078.1 /DEF=Homo sapiens cysteine and glycine-rich protein 1 (CSRP1), mRNA. /FEA=mRNA /GEN=CSRP1 /PROD=cysteine and glycine-rich protein 1 /DB_XREF=gi:4758085 /UG=Hs.108080 cysteine and glycine-rich protein 1 /FL=gb:M33146.1 gb:NM_004078.1 NM_004078 cysteine and glycine-rich protein 1 CSRP1 1465 NM_004078 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200622_x_at AV685208 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV685208 /FEA=EST /DB_XREF=gi:10287071 /DB_XREF=est:AV685208 /CLONE=GKCCXA06 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1 AV685208 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001743 /// NM_005184 /// NM_006888 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction 200623_s_at NM_005184 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005184.1 /DEF=Homo sapiens calmodulin 3 (phosphorylase kinase, delta) (CALM3), mRNA. /FEA=mRNA /GEN=CALM3 /PROD=calmodulin 3 (phosphorylase kinase, delta) /DB_XREF=gi:4885108 /UG=Hs.141011 calmodulin 3 (phosphorylase kinase, delta) /FL=gb:BC005137.1 gb:J04046.1 gb:NM_005184.1 NM_005184 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001743 /// NM_005184 /// NM_006888 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction 200624_s_at AA577695 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA577695 /FEA=EST /DB_XREF=gi:2355879 /DB_XREF=est:nn22h02.s1 /CLONE=IMAGE:1084659 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1 AA577695 matrin 3 MATR3 9782 NM_018834 /// NM_199189 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200625_s_at NM_006367 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006367.2 /DEF=Homo sapiens adenylyl cyclase-associated protein (CAP), mRNA. /FEA=mRNA /GEN=CAP /PROD=adenylyl cyclase-associated protein /DB_XREF=gi:10938021 /UG=Hs.104125 adenylyl cyclase-associated protein /FL=gb:NM_006367.2 gb:L12168.1 gb:M98474.1 NM_006367 CAP, adenylate cyclase-associated protein 1 (yeast) CAP1 10487 NM_001105530 /// NM_006367 0000902 // cell morphogenesis // inferred from electronic annotation /// 0001667 // ameboidal cell migration // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 200626_s_at NM_018834 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018834.1 /DEF=Homo sapiens matrin 3 (MATR3), mRNA. /FEA=mRNA /GEN=MATR3 /PROD=matrin 3 /DB_XREF=gi:10047081 /UG=Hs.78825 matrin 3 /FL=gb:NM_018834.1 gb:AB018266.1 NM_018834 matrin 3 MATR3 9782 NM_018834 /// NM_199189 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // traceable author statement /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200627_at BC003005 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003005.1 /DEF=Homo sapiens, unactive progesterone receptor, 23 kD, clone MGC:4004, mRNA, complete cds. /FEA=mRNA /PROD=unactive progesterone receptor, 23 kD /DB_XREF=gi:12804292 /UG=Hs.278270 unactive progesterone receptor, 23 kD /FL=gb:BC003005.1 gb:L24804.1 gb:NM_006601.1 BC003005 prostaglandin E synthase 3 (cytosolic) PTGES3 10728 NM_006601 0000723 // telomere maintenance // traceable author statement /// 0001516 // prostaglandin biosynthetic process // inferred from direct assay /// 0001516 // prostaglandin biosynthetic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from electronic annotation 0000781 // chromosome, telomeric region // inferred by curator /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0050220 // prostaglandin-E synthase activity // inferred from direct assay /// 0050220 // prostaglandin-E synthase activity // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from direct assay 200628_s_at M61715 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M61715.1 /DEF=Human tryptophanyl-tRNA synthetase (WRS) mRNA, complete cds. /FEA=mRNA /GEN=WARS /PROD=transfer RNA-Trp synthetase /DB_XREF=gi:340367 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2 M61715 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006436 // tryptophanyl-tRNA aminoacylation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200629_at NM_004184 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004184.2 /DEF=Homo sapiens tryptophanyl-tRNA synthetase (WARS), mRNA. /FEA=mRNA /GEN=WARS /PROD=tryptophanyl-tRNA synthetase /DB_XREF=gi:7710155 /UG=Hs.82030 tryptophanyl-tRNA synthetase /FL=gb:M77804.1 gb:M61715.1 gb:NM_004184.2 NM_004184 tryptophanyl-tRNA synthetase WARS 7453 NM_004184 /// NM_173701 /// NM_213645 /// NM_213646 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006436 // tryptophanyl-tRNA aminoacylation // traceable author statement /// 0006436 // tryptophanyl-tRNA aminoacylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004830 // tryptophan-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200630_x_at AV702810 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV702810 /FEA=EST /DB_XREF=gi:10719140 /DB_XREF=est:AV702810 /CLONE=ADBDGH01 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1 AV702810 SET nuclear oncogene SET 6418 NM_001122821 /// NM_003011 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200631_s_at NM_003011 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003011.1 /DEF=Homo sapiens SET translocation (myeloid leukemia-associated) (SET), mRNA. /FEA=mRNA /GEN=SET /PROD=SET translocation (myeloid leukemia-associated) /DB_XREF=gi:4506890 /UG=Hs.145279 SET translocation (myeloid leukemia-associated) /FL=gb:U51924.1 gb:M93651.1 gb:NM_003011.1 NM_003011 SET nuclear oncogene SET 6418 NM_001122821 /// NM_003011 0006260 // DNA replication // traceable author statement /// 0006334 // nucleosome assembly // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0006337 // nucleosome disassembly // traceable author statement /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0035067 // negative regulation of histone acetylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004864 // protein phosphatase inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0042393 // histone binding // traceable author statement 200632_s_at NM_006096 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006096.1 /DEF=Homo sapiens N-myc downstream regulated (NDRG1), mRNA. /FEA=mRNA /GEN=NDRG1 /PROD=N-myc downstream regulated /DB_XREF=gi:5174656 /UG=Hs.75789 N-myc downstream regulated /FL=gb:BC003175.1 gb:D87953.1 gb:AF004162.1 gb:NM_006096.1 NM_006096 N-myc downstream regulated 1 NDRG1 10397 NM_001135242 /// NM_006096 0010038 // response to metal ion // traceable author statement /// 0045576 // mast cell activation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200633_at NM_018955 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018955.1 /DEF=Homo sapiens ubiquitin B (UBB), mRNA. /FEA=mRNA /GEN=UBB /PROD=ubiquitin B /DB_XREF=gi:11024713 /UG=Hs.183842 ubiquitin B /FL=gb:NM_018955.1 gb:BC000379.1 NM_018955 ribosomal protein S27a /// ubiquitin B /// ubiquitin C RPS27A /// UBB /// UBC 6233 /// 7314 /// 7316 NM_001135592 /// NM_002954 /// NM_018955 /// NM_021009 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006464 // protein modification process // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030433 // ER-associated protein catabolic process // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042062 // long-term strengthening of neuromuscular junction // traceable author statement /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // traceable author statement /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation 200634_at NM_005022 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005022.1 /DEF=Homo sapiens profilin 1 (PFN1), mRNA. /FEA=mRNA /GEN=PFN1 /PROD=profilin 1 /DB_XREF=gi:4826897 /UG=Hs.75721 profilin 1 /FL=gb:BC002475.1 gb:J03191.1 gb:NM_005022.1 NM_005022 profilin 1 PFN1 5216 NM_005022 0001843 // neural tube closure // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200635_s_at AU145351 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU145351 /FEA=EST /DB_XREF=gi:11006872 /DB_XREF=est:AU145351 /CLONE=HEMBA1004591 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 AU145351 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200636_s_at NM_002840 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002840.1 /DEF=Homo sapiens protein tyrosine phosphatase, receptor type, F (PTPRF), mRNA. /FEA=mRNA /GEN=PTPRF /PROD=protein tyrosine phosphatase, receptor type, fpolypeptide /DB_XREF=gi:4506310 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 NM_002840 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200637_s_at AI762627 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI762627 /FEA=EST /DB_XREF=gi:5178294 /DB_XREF=est:wi56g01.x1 /CLONE=IMAGE:2394288 /UG=Hs.75216 protein tyrosine phosphatase, receptor type, F /FL=gb:NM_002840.1 AI762627 protein tyrosine phosphatase, receptor type, F PTPRF 5792 NM_002840 /// NM_130440 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007185 // transmembrane receptor protein tyrosine phosphatase signaling pathway // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005001 // transmembrane receptor protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200638_s_at BC003623 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003623.1 /DEF=Homo sapiens, tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide, clone MGC:2153, mRNA, complete cds. /FEA=mRNA /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:13177678 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 BC003623 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200639_s_at NM_003406 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 NM_003406 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200640_at NM_003406 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003406.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide (YWHAZ), mRNA. /FEA=mRNA /GEN=YWHAZ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, zeta polypeptide /DB_XREF=gi:4507952 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 NM_003406 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200641_s_at U28964 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U28964.1 /DEF=Homo sapiens 14-3-3 protein mRNA, complete cds. /FEA=mRNA /PROD=14-3-3 protein /DB_XREF=gi:899458 /UG=Hs.75103 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, zeta polypeptide /FL=gb:BC003623.1 gb:M86400.1 gb:NM_003406.1 gb:U28964.1 U28964 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide YWHAZ 7534 NM_001135699 /// NM_001135700 /// NM_001135701 /// NM_001135702 /// NM_003406 /// NM_145690 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019904 // protein domain specific binding // inferred from electronic annotation 200642_at NM_000454 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000454.1 /DEF=Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA. /FEA=mRNA /GEN=SOD1 /PROD=superoxide dismutase 1, soluble (amyotrophiclateral sclerosis 1 (adult)) /DB_XREF=gi:4507148 /UG=Hs.75428 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) /FL=gb:BC001034.1 gb:K00065.1 gb:NM_000454.1 NM_000454 superoxide dismutase 1, soluble SOD1 6647 NM_000454 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0000187 // activation of MAPK activity // inferred from electronic annotation /// 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0000303 // response to superoxide // inferred from direct assay /// 0000303 // response to superoxide // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from sequence or structural similarity /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0001819 // positive regulation of cytokine production // inferred from direct assay /// 0001890 // placenta development // non-traceable author statement /// 0001895 // retina homeostasis // inferred from sequence or structural similarity /// 0001895 // retina homeostasis // inferred from electronic annotation /// 0002262 // myeloid cell homeostasis // inferred from sequence or structural similarity /// 0002262 // myeloid cell homeostasis // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from sequence or structural similarity /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006309 // DNA fragmentation during apoptosis // inferred from sequence or structural similarity /// 0006309 // DNA fragmentation during apoptosis // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from sequence or structural similarity /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from electronic annotation /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006879 // cellular iron ion homeostasis // inferred from sequence or structural similarity /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from expression pattern /// 0007283 // spermatogenesis // inferred from sequence or structural similarity /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from sequence or structural similarity /// 0007566 // embryo implantation // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007569 // cell aging // inferred from expression pattern /// 0007569 // cell aging // inferred from mutant phenotype /// 0007605 // sensory perception of sound // inferred from sequence or structural similarity /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from sequence or structural similarity /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from sequence or structural similarity /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from direct assay /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0019226 // transmission of nerve impulse // inferred from electronic annotation /// 0019430 // removal of superoxide radicals // inferred from sequence or structural similarity /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032287 // myelin maintenance in the peripheral nervous system // inferred from sequence or structural similarity /// 0032287 // myelin maintenance in the peripheral nervous system // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in the thymus // non-traceable author statement /// 0040014 // regulation of multicellular organism growth // inferred from sequence or structural similarity /// 0040014 // regulation of multicellular organism growth // inferred from electronic annotation /// 0042493 // response to drug // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from sequence or structural similarity /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042554 // superoxide release // inferred from electronic annotation /// 0043065 // positive regulation of apoptosis // inferred by curator /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043085 // positive regulation of catalytic activity // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptosis // inferred from sequence or structural similarity /// 0043524 // negative regulation of neuron apoptosis // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045541 // negative regulation of cholesterol biosynthetic process // inferred from direct assay /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0046620 // regulation of organ growth // non-traceable author statement /// 0046688 // response to copper ion // inferred from electronic annotation /// 0046716 // muscle maintenance // inferred from sequence or structural similarity /// 0046716 // muscle maintenance // inferred from electronic annotation /// 0048538 // thymus development // non-traceable author statement /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0048678 // response to axon injury // inferred from electronic annotation /// 0050665 // hydrogen peroxide biosynthetic process // inferred from direct assay /// 0050665 // hydrogen peroxide biosynthetic process // inferred from sequence or structural similarity /// 0050665 // hydrogen peroxide biosynthetic process // inferred from electronic annotation /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation reduction // inferred from electronic annotation /// 0060047 // heart contraction // inferred from direct assay /// 0060047 // heart contraction // inferred from electronic annotation /// 0060052 // neurofilament cytoskeleton organization // inferred from sequence or structural similarity /// 0060052 // neurofilament cytoskeleton organization // inferred from electronic annotation /// 0060087 // relaxation of vascular smooth muscle // inferred from sequence or structural similarity /// 0060087 // relaxation of vascular smooth muscle // inferred from electronic annotation /// 0060088 // auditory receptor cell stereocilium organization // inferred from sequence or structural similarity /// 0060088 // auditory receptor cell stereocilium organization // inferred from electronic annotation 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005777 // peroxisome // non-traceable author statement /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from direct assay /// 0032839 // dendrite cytoplasm // inferred from direct assay /// 0043025 // cell soma // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay 0004784 // superoxide dismutase activity // inferred from direct assay /// 0004784 // superoxide dismutase activity // inferred from electronic annotation /// 0005507 // copper ion binding // inferred from direct assay /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0030346 // protein phosphatase 2B binding // inferred from direct assay /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from physical interaction 200643_at NM_005336 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005336.1 /DEF=Homo sapiens high density lipoprotein binding protein (vigilin) (HDLBP), mRNA. /FEA=mRNA /GEN=HDLBP /PROD=high density lipoprotein binding protein /DB_XREF=gi:4885408 /UG=Hs.177516 high density lipoprotein binding protein (vigilin) /FL=gb:BC001179.1 gb:M64098.1 gb:NM_005336.1 NM_005336 high density lipoprotein binding protein HDLBP 3069 NM_005336 /// NM_203346 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0008203 // cholesterol metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0003723 // RNA binding // inferred from electronic annotation /// 0005319 // lipid transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // traceable author statement 200644_at NM_023009 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_023009.1 /DEF=Homo sapiens macrophage myristoylated alanine-rich C kinase substrate (MACMARCKS), mRNA. /FEA=mRNA /GEN=MACMARCKS /PROD=macrophage myristoylated alanine-rich C kinasesubstrate /DB_XREF=gi:13491173 /UG=Hs.75061 macrophage myristoylated alanine-rich C kinase substrate /FL=gb:NM_023009.1 NM_023009 MARCKS-like 1 MARCKSL1 65108 NM_023009 0005886 // plasma membrane // inferred from direct assay 0005516 // calmodulin binding // inferred from electronic annotation 200645_at NM_007278 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007278.1 /DEF=Homo sapiens GABA(A) receptor-associated protein (GABARAP), mRNA. /FEA=mRNA /GEN=GABARAP /PROD=GABA(A) receptor-associated protein /DB_XREF=gi:6005763 /UG=Hs.7719 GABA(A) receptor-associated protein /FL=gb:AB030711.1 gb:AF044671.1 gb:AF067171.1 gb:AF161586.1 gb:NM_007278.1 gb:AF183425.1 NM_007278 GABA(A) receptor-associated protein GABARAP 11337 NM_007278 0006605 // protein targeting // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0000421 // autophagic vacuole membrane // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0048487 // beta-tubulin binding // inferred from direct assay /// 0050811 // GABA receptor binding // inferred from physical interaction 200646_s_at NM_006184 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006184.1 /DEF=Homo sapiens nucleobindin 1 (NUCB1), mRNA. /FEA=mRNA /GEN=NUCB1 /PROD=nucleobindin 1 /DB_XREF=gi:5453817 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1 NM_006184 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 200647_x_at NM_003752 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003752.2 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 8 (110kD) (EIF3S8), mRNA. /FEA=mRNA /GEN=EIF3S8 /PROD=eukaryotic translation initiation factor 3,subunit 8 (110kD) /DB_XREF=gi:5579457 /UG=Hs.4835 eukaryotic translation initiation factor 3, subunit 8 (110kD) /FL=gb:NM_003752.2 NM_003752 eukaryotic translation initiation factor 3, subunit C /// eukaryotic translation initiation factor 3, subunit C-like EIF3C /// EIF3CL 728689 /// 8663 NM_001037808 /// NM_001099661 /// NM_003752 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0005852 // eukaryotic translation initiation factor 3 complex // inferred from electronic annotation 0003743 // translation initiation factor activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200648_s_at NM_002065 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002065.1 /DEF=Homo sapiens glutamate-ammonia ligase (glutamine synthase) (GLUL), mRNA. /FEA=mRNA /GEN=GLUL /PROD=glutamate-ammonia ligase (glutamine synthase) /DB_XREF=gi:4504026 /UG=Hs.170171 glutamate-ammonia ligase (glutamine synthase) /FL=gb:NM_002065.1 NM_002065 glutamate-ammonia ligase (glutamine synthetase) GLUL 2752 NM_001033044 /// NM_001033056 /// NM_002065 0006542 // glutamine biosynthetic process // inferred from electronic annotation /// 0006807 // nitrogen compound metabolic process // inferred from electronic annotation /// 0009749 // response to glucose stimulus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004356 // glutamate-ammonia ligase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200649_at BC002356 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002356.1 /DEF=Homo sapiens, nucleobindin 1, clone MGC:8479, mRNA, complete cds. /FEA=mRNA /PROD=nucleobindin 1 /DB_XREF=gi:12803104 /UG=Hs.172609 nucleobindin 1 /FL=gb:BC002356.1 gb:M96824.1 gb:NM_006184.1 BC002356 nucleobindin 1 NUCB1 4924 NM_006184 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation 200650_s_at NM_005566 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005566.1 /DEF=Homo sapiens lactate dehydrogenase A (LDHA), mRNA. /FEA=mRNA /GEN=LDHA /PROD=LDHA /DB_XREF=gi:5031856 /UG=Hs.2795 lactate dehydrogenase A /FL=gb:BC001829.1 gb:NM_005566.1 NM_005566 lactate dehydrogenase A LDHA 3939 NM_001135239 /// NM_005566 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019642 // anaerobic glycolysis // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // traceable author statement /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 200651_at NM_006098 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006098.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1), mRNA. /FEA=mRNA /GEN=GNB2L1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2-like 1 /DB_XREF=gi:5174446 /UG=Hs.5662 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 /FL=gb:BC000214.1 gb:BC000366.1 gb:BC000672.1 gb:M24194.1 gb:NM_006098.1 NM_006098 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 GNB2L1 10399 NM_006098 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043025 // cell soma // inferred from electronic annotation 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200652_at NM_003145 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003145.2 /DEF=Homo sapiens signal sequence receptor, beta (translocon-associated protein beta) (SSR2), mRNA. /FEA=mRNA /GEN=SSR2 /PROD=signal sequence receptor, beta precursor /DB_XREF=gi:6552341 /UG=Hs.74564 signal sequence receptor, beta (translocon-associated protein beta) /FL=gb:D37991.1 gb:BC000341.1 gb:NM_003145.2 NM_003145 signal sequence receptor, beta (translocon-associated protein beta) SSR2 6746 NM_003145 0006613 // cotranslational protein targeting to membrane // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005048 // signal sequence binding // traceable author statement 200653_s_at M27319 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M27319.1 /DEF=Human calmodulin mRNA, complete cds. /FEA=mRNA /PROD=calmodulin /DB_XREF=gi:179809 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1 M27319 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001743 /// NM_005184 /// NM_006888 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction 200654_at J02783 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J02783.1 /DEF=Human thyroid hormone binding protein (p55) mRNA, complete cds. /FEA=mRNA /GEN=P4HB /DB_XREF=gi:339646 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1 J02783 prolyl 4-hydroxylase, beta polypeptide P4HB 5034 NM_000918 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // traceable author statement /// 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0004656 // procollagen-proline 4-dioxygenase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 200655_s_at NM_006888 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006888.1 /DEF=Homo sapiens calmodulin 1 (phosphorylase kinase, delta) (CALM1), mRNA. /FEA=mRNA /GEN=CALM1 /PROD=calmodulin 1 (phosphorylase kinase, delta) /DB_XREF=gi:5901911 /UG=Hs.177656 calmodulin 1 (phosphorylase kinase, delta) /FL=gb:M27319.1 gb:NM_006888.1 NM_006888 calmodulin 1 (phosphorylase kinase, delta) /// calmodulin 2 (phosphorylase kinase, delta) /// calmodulin 3 (phosphorylase kinase, delta) CALM1 /// CALM2 /// CALM3 801 /// 805 /// 808 NM_001743 /// NM_005184 /// NM_006888 0007049 // cell cycle // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0032465 // regulation of cytokinesis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from direct assay 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005876 // spindle microtubule // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0031432 // titin binding // inferred from physical interaction /// 0031997 // N-terminal myristoylation domain binding // inferred from physical interaction 200656_s_at NM_000918 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000918.1 /DEF=Homo sapiens procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) (P4HB), mRNA. /FEA=mRNA /GEN=P4HB /PROD=procollagen-proline, 2-oxoglutarate4-dioxygenase (proline 4-hydroxylase), beta polypeptide(protein disulfide isomerase; thyroid hormone bindingprotein p55) /DB_XREF=gi:4505566 /UG=Hs.75655 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55) /FL=gb:J02783.1 gb:NM_000918.1 NM_000918 prolyl 4-hydroxylase, beta polypeptide P4HB 5034 NM_000918 0018401 // peptidyl-proline hydroxylation to 4-hydroxy-L-proline // inferred from direct assay /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // traceable author statement /// 0003756 // protein disulfide isomerase activity // inferred from electronic annotation /// 0004656 // procollagen-proline 4-dioxygenase activity // inferred from direct assay /// 0004656 // procollagen-proline 4-dioxygenase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 200657_at NM_001152 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001152.1 /DEF=Homo sapiens solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (SLC25A5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SLC25A5 /PROD=solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 5 /DB_XREF=gi:4502098 /UG=Hs.79172 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 /FL=gb:J02683.1 gb:NM_001152.1 NM_001152 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 SLC25A5 292 NM_001152 0006810 // transport // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // not recorded /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0015207 // adenine transmembrane transporter activity // traceable author statement 200658_s_at AL560017 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL560017 /FEA=EST /DB_XREF=gi:12906073 /DB_XREF=est:AL560017 /CLONE=CS0DG004YD08 (5 prime) /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2 AL560017 prohibitin PHB 5245 NM_002634 0006260 // DNA replication // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0042981 // regulation of apoptosis // traceable author statement /// 0045449 // regulation of transcription // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // inferred from direct assay /// 0016564 // transcription repressor activity // inferred from direct assay 200659_s_at NM_002634 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002634.2 /DEF=Homo sapiens prohibitin (PHB), mRNA. /FEA=mRNA /GEN=PHB /PROD=prohibitin /DB_XREF=gi:6031190 /UG=Hs.75323 prohibitin /FL=gb:NM_002634.2 NM_002634 prohibitin PHB 5245 NM_002634 0006260 // DNA replication // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // non-traceable author statement /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0016575 // histone deacetylation // inferred from direct assay /// 0042981 // regulation of apoptosis // traceable author statement /// 0045449 // regulation of transcription // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // inferred from direct assay /// 0016564 // transcription repressor activity // inferred from direct assay 200660_at NM_005620 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005620.1 /DEF=Homo sapiens S100 calcium-binding protein A11 (calgizzarin) (S100A11), mRNA. /FEA=mRNA /GEN=S100A11 /PROD=S100 calcium-binding protein A11 /DB_XREF=gi:5032056 /UG=Hs.256290 S100 calcium-binding protein A11 (calgizzarin) /FL=gb:D49355.1 gb:BC001410.1 gb:D50374.1 gb:NM_005620.1 gb:D38583.1 NM_005620 S100 calcium binding protein A11 S100A11 6282 NM_005620 0007165 // signal transduction // traceable author statement /// 0008156 // negative regulation of DNA replication // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048154 // S100 beta binding // inferred from physical interaction /// 0048306 // calcium-dependent protein binding // inferred from direct assay 200661_at NM_000308 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000308.1 /DEF=Homo sapiens protective protein for beta-galactosidase (galactosialidosis) (PPGB), mRNA. /FEA=mRNA /GEN=PPGB /PROD=protective protein for beta-galactosidase /DB_XREF=gi:4505988 /UG=Hs.118126 protective protein for beta-galactosidase (galactosialidosis) /FL=gb:BC000597.1 gb:M22960.1 gb:NM_000308.1 NM_000308 cathepsin A CTSA 5476 NM_000308 /// NM_001127695 0006508 // proteolysis // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004185 // serine-type carboxypeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008047 // enzyme activator activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200662_s_at NM_014765 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014765.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 20 (yeast) homolog (KIAA0016), mRNA. /FEA=mRNA /GEN=KIAA0016 /PROD=translocase of outer mitochondrial membrane 20(yeast) homolog /DB_XREF=gi:7657256 /UG=Hs.75187 translocase of outer mitochondrial membrane 20 (yeast) homolog /FL=gb:BC000882.1 gb:D13641.1 gb:NM_014765.1 NM_014765 translocase of outer mitochondrial membrane 20 homolog (yeast) TOMM20 9804 NM_014765 0006605 // protein targeting // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043681 // protein import into mitochondrion // inferred from direct assay 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // non-traceable author statement /// 0005742 // mitochondrial outer membrane translocase complex // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from direct assay 200663_at NM_001780 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001780.1 /DEF=Homo sapiens CD63 antigen (melanoma 1 antigen) (CD63), mRNA. /FEA=mRNA /GEN=CD63 /PROD=CD63 antigen (melanoma 1 antigen) /DB_XREF=gi:4502678 /UG=Hs.76294 CD63 antigen (melanoma 1 antigen) /FL=gb:BC002349.1 gb:M59907.1 gb:NM_001780.1 NM_001780 CD63 molecule CD63 967 NM_001040034 /// NM_001780 0045807 // positive regulation of endocytosis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 200664_s_at BG537255 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG537255 /FEA=EST /DB_XREF=gi:13529117 /DB_XREF=est:602565318F1 /CLONE=IMAGE:4689748 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1 BG537255 DnaJ (Hsp40) homolog, subfamily B, member 1 DNAJB1 3337 NM_006145 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0051085 // chaperone cofactor-dependent protein folding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0031072 // heat shock protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200665_s_at NM_003118 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003118.1 /DEF=Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin) (SPARC), mRNA. /FEA=mRNA /GEN=SPARC /PROD=secreted protein, acidic, cysteine-rich(osteonectin) /DB_XREF=gi:4507170 /UG=Hs.111779 secreted protein, acidic, cysteine-rich (osteonectin) /FL=gb:BC004974.1 gb:J03040.1 gb:NM_003118.1 NM_003118 secreted protein, acidic, cysteine-rich (osteonectin) SPARC 6678 NM_003118 0001503 // ossification // traceable author statement /// 0002446 // neutrophil mediated immunity // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0032956 // regulation of actin cytoskeleton organization // inferred from electronic annotation /// 0043312 // neutrophil degranulation // inferred from electronic annotation /// 0045088 // regulation of innate immune response // inferred from electronic annotation /// 0050830 // defense response to Gram-positive bacterium // inferred from electronic annotation 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0016461 // unconventional myosin complex // non-traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // not recorded /// 0031941 // filamentous actin // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005507 // copper ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // non-traceable author statement /// 0005518 // collagen binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement 200666_s_at NM_006145 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006145.1 /DEF=Homo sapiens heat shock 40kD protein 1 (HSPF1), mRNA. /FEA=mRNA /GEN=HSPF1 /PROD=heat shock 40kD protein 1 /DB_XREF=gi:5453689 /UG=Hs.82646 DnaJ (Hsp40) homolog, subfamily B, member 1 /FL=gb:BC002352.1 gb:NM_006145.1 gb:D49547.1 NM_006145 DnaJ (Hsp40) homolog, subfamily B, member 1 DNAJB1 3337 NM_006145 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0051085 // chaperone cofactor-dependent protein folding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0031072 // heat shock protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 200667_at BF448062 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF448062 /FEA=EST /DB_XREF=gi:11513123 /DB_XREF=est:7q97h09.x1 /CLONE=IMAGE:3706600 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 BF448062 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // not recorded /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 200668_s_at BC003395 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003395.1 /DEF=Homo sapiens, ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45), clone MGC:5416, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:13097281 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 BC003395 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // not recorded /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 200669_s_at NM_003340 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003340.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) (UBE2D3), mRNA. /FEA=mRNA /GEN=UBE2D3 /PROD=ubiquitin-conjugating enzyme E2D 3 (homologousto yeast UBC45) /DB_XREF=gi:4507776 /UG=Hs.118797 ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC45) /FL=gb:U39318.1 gb:BC003395.1 gb:NM_003340.1 NM_003340 ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) UBE2D3 7323 NM_003340 /// NM_181886 /// NM_181887 /// NM_181888 /// NM_181889 /// NM_181890 /// NM_181891 /// NM_181892 /// NM_181893 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030509 // BMP signaling pathway // not recorded /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 200670_at NM_005080 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005080.1 /DEF=Homo sapiens X-box binding protein 1 (XBP1), mRNA. /FEA=mRNA /GEN=XBP1 /PROD=X-box binding protein 1 /DB_XREF=gi:4827057 /UG=Hs.149923 X-box binding protein 1 /FL=gb:BC000938.1 gb:M31627.1 gb:NM_005080.1 NM_005080 X-box binding protein 1 XBP1 7494 NM_001079539 /// NM_005080 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0045449 // regulation of transcription // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 200671_s_at N92501 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N92501 /FEA=EST /DB_XREF=gi:1264810 /DB_XREF=est:zb28a07.s1 /CLONE=IMAGE:304884 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1 N92501 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein nuclear translocation // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008091 // spectrin // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003779 // actin binding // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 200672_x_at NM_003128 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003128.1 /DEF=Homo sapiens spectrin, beta, non-erythrocytic 1 (SPTBN1), mRNA. /FEA=mRNA /GEN=SPTBN1 /PROD=spectrin, beta, non-erythrocytic 1 /DB_XREF=gi:4507194 /UG=Hs.107164 spectrin, beta, non-erythrocytic 1 /FL=gb:M96803.1 gb:NM_003128.1 NM_003128 spectrin, beta, non-erythrocytic 1 SPTBN1 6711 NM_003128 /// NM_178313 0007182 // common-partner SMAD protein phosphorylation // inferred from electronic annotation /// 0007184 // SMAD protein nuclear translocation // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0008091 // spectrin // traceable author statement /// 0008091 // spectrin // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003779 // actin binding // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation 200673_at NM_014713 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014713.2 /DEF=Homo sapiens lysosomal-associated protein transmembrane 4 alpha (MBNT), mRNA. /FEA=mRNA /GEN=MBNT /PROD=lysosomal-associated protein transmembrane 4alpha /DB_XREF=gi:13518239 /UG=Hs.111894 lysosomal-associated protein transmembrane 4 alpha /FL=gb:BC000421.1 gb:BC003158.1 gb:NM_014713.2 gb:D14696.1 NM_014713 lysosomal protein transmembrane 4 alpha LAPTM4A 9741 NM_014713 0006810 // transport // inferred from electronic annotation 0005794 // Golgi apparatus // inferred from direct assay /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200674_s_at NM_000994 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000994.1 /DEF=Homo sapiens ribosomal protein L32 (RPL32), mRNA. /FEA=mRNA /GEN=RPL32 /PROD=ribosomal protein L32 /DB_XREF=gi:4506634 /UG=Hs.169793 ribosomal protein L32 /FL=gb:NM_000994.1 NM_000994 ribosomal protein L32 RPL32 6161 NM_000994 /// NM_001007073 /// NM_001007074 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200675_at NM_004356 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004356.1 /DEF=Homo sapiens CD81 antigen (target of antiproliferative antibody 1) (CD81), mRNA. /FEA=mRNA /GEN=CD81 /PROD=CD81 antigen (target of antiproliferativeantibody 1) /DB_XREF=gi:4757943 /UG=Hs.54457 CD81 antigen (target of antiproliferative antibody 1) /FL=gb:BC002978.1 gb:M33680.1 gb:NM_004356.1 NM_004356 CD81 molecule CD81 975 NM_004356 0000187 // activation of MAPK activity // inferred from direct assay /// 0006661 // phosphatidylinositol biosynthetic process // inferred from direct assay /// 0006952 // defense response // traceable author statement /// 0008104 // protein localization // inferred from direct assay /// 0008283 // cell proliferation // traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0030384 // phosphoinositide metabolic process // inferred from direct assay /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043128 // positive regulation of 1-phosphatidylinositol 4-kinase activity // inferred from direct assay /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0046718 // entry of virus into host cell // traceable author statement /// 0046813 // virion attachment, binding of host cell surface receptor // traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from direct assay 0005887 // integral to plasma membrane // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200676_s_at NM_003347 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003347.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), mRNA. /FEA=mRNA /GEN=UBE2L3 /PROD=ubiquitin-conjugating enzyme E2L 3 /DB_XREF=gi:4507788 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 NM_003347 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_003347 /// NM_198157 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement 200677_at NM_004339 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004339.2 /DEF=Homo sapiens pituitary tumor-transforming 1 interacting protein (PTTG1IP), mRNA. /FEA=mRNA /GEN=PTTG1IP /PROD=pituitary tumor-transforming protein1-interacting protein precursor /DB_XREF=gi:11038670 /UG=Hs.111126 pituitary tumor-transforming 1 interacting protein /FL=gb:NM_004339.2 gb:BC000415.1 gb:AF149785.1 NM_004339 pituitary tumor-transforming 1 interacting protein PTTG1IP 754 NM_004339 0006606 // protein import into nucleus // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200678_x_at NM_002087 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002087.1 /DEF=Homo sapiens granulin (GRN), mRNA. /FEA=mRNA /GEN=GRN /PROD=granulin /DB_XREF=gi:4504150 /UG=Hs.180577 granulin /FL=gb:M75161.1 gb:AF055008.1 gb:NM_002087.1 NM_002087 granulin GRN 2896 NM_002087 0001835 // blastocyst hatching // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007566 // embryo implantation // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation 0004623 // phospholipase A2 activity // inferred from electronic annotation /// 0005125 // cytokine activity // inferred from electronic annotation /// 0008083 // growth factor activity // traceable author statement 200679_x_at BE311760 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE311760 /FEA=EST /DB_XREF=gi:9148272 /DB_XREF=est:601143587F1 /CLONE=IMAGE:3507284 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1 BE311760 high-mobility group box 1 HMGB1 3146 NM_002128 0006268 // DNA unwinding during replication // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006310 // DNA recombination // traceable author statement /// 0006325 // establishment or maintenance of chromatin architecture // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0017055 // negative regulation of transcriptional preinitiation complex assembly // inferred from direct assay 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0008301 // DNA bending activity // traceable author statement 200680_x_at NM_002128 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002128.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 1 (HMG1), mRNA. /FEA=mRNA /GEN=HMG1 /PROD=high-mobility group (nonhistone chromosomal)protein 1 /DB_XREF=gi:4504424 /UG=Hs.274472 high-mobility group (nonhistone chromosomal) protein 1 /FL=gb:BC003378.1 gb:NM_002128.1 gb:D63874.1 NM_002128 high-mobility group box 1 HMGB1 3146 NM_002128 0006268 // DNA unwinding during replication // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006288 // base-excision repair, DNA ligation // inferred from direct assay /// 0006310 // DNA recombination // traceable author statement /// 0006325 // establishment or maintenance of chromatin architecture // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0017055 // negative regulation of transcriptional preinitiation complex assembly // inferred from direct assay 0000793 // condensed chromosome // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0008301 // DNA bending activity // traceable author statement 200681_at NM_006708 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006708.1 /DEF=Homo sapiens glyoxalase I (GLO1), mRNA. /FEA=mRNA /GEN=GLO1 /PROD=glyoxalase I /DB_XREF=gi:5729841 /UG=Hs.75207 glyoxalase I /FL=gb:BC001741.1 gb:L07837.1 gb:NM_006708.1 NM_006708 glyoxalase I GLO1 2739 NM_006708 0005975 // carbohydrate metabolic process // non-traceable author statement /// 0006916 // anti-apoptosis // inferred from direct assay /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006916 // anti-apoptosis // traceable author statement 0005737 // cytoplasm // traceable author statement 0004462 // lactoylglutathione lyase activity // inferred from direct assay /// 0004462 // lactoylglutathione lyase activity // inferred from electronic annotation /// 0004462 // lactoylglutathione lyase activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200682_s_at BG531983 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG531983 /FEA=EST /DB_XREF=gi:13523521 /DB_XREF=est:602561007F1 /CLONE=IMAGE:4699176 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BG531983 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_003347 /// NM_198157 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement 200683_s_at BE964689 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE964689 /FEA=EST /DB_XREF=gi:11768267 /DB_XREF=est:601658226R1 /CLONE=IMAGE:3885630 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 BE964689 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_003347 /// NM_198157 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement 200684_s_at AI819709 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI819709 /FEA=EST /DB_XREF=gi:5438788 /DB_XREF=est:wj77c07.x1 /CLONE=IMAGE:2408844 /UG=Hs.108104 ubiquitin-conjugating enzyme E2L 3 /FL=gb:NM_003347.1 AI819709 ubiquitin-conjugating enzyme E2L 3 UBE2L3 7332 NM_003347 /// NM_198157 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0000151 // ubiquitin ligase complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0019899 // enzyme binding // traceable author statement 200685_at AU146237 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU146237 /FEA=EST /DB_XREF=gi:11007758 /DB_XREF=est:AU146237 /CLONE=HEMBA1007233 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1 AU146237 splicing factor, arginine/serine-rich 11 SFRS11 9295 NM_004768 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200686_s_at NM_004768 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004768.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 11 (SFRS11), mRNA. /FEA=mRNA /GEN=SFRS11 /PROD=splicing factor, arginineserine-rich 11 /DB_XREF=gi:4759099 /UG=Hs.11482 splicing factor, arginineserine-rich 11 /FL=gb:M74002.1 gb:NM_004768.1 NM_004768 splicing factor, arginine/serine-rich 11 SFRS11 9295 NM_004768 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200687_s_at NM_012426 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012426.1 /DEF=Homo sapiens splicing factor 3b, subunit 3, 130kD (SF3B3), mRNA. /FEA=mRNA /GEN=SF3B3 /PROD=splicing factor 3b, subunit 3, 130kD /DB_XREF=gi:11034822 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1 NM_012426 splicing factor 3b, subunit 3, 130kDa SF3B3 23450 NM_012426 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200688_at D13642 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D13642.1 /DEF=Human mRNA for KIAA0017 gene, complete cds. /FEA=mRNA /GEN=KIAA0017 /DB_XREF=gi:285998 /UG=Hs.195614 splicing factor 3b, subunit 3, 130kD /FL=gb:NM_012426.1 gb:BC000463.1 gb:BC003146.1 gb:D13642.1 gb:D87686.1 D13642 splicing factor 3b, subunit 3, 130kDa SF3B3 23450 NM_012426 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200689_x_at NM_001404 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001404.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA. /FEA=mRNA /GEN=EEF1G /PROD=eukaryotic translation elongation factor 1gamma /DB_XREF=gi:4503480 /UG=Hs.2186 eukaryotic translation elongation factor 1 gamma /FL=gb:BC000384.1 gb:BC004189.1 gb:BC004215.1 gb:NM_001404.1 NM_001404 eukaryotic translation elongation factor 1 gamma EEF1G 1937 NM_001404 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // non-traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // non-traceable author statement /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation 200690_at AA927701 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA927701 /FEA=EST /DB_XREF=gi:3076521 /DB_XREF=est:om72d09.s1 /CLONE=IMAGE:1552721 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 AA927701 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200691_s_at BC000478 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000478.1 /DEF=Homo sapiens, heat shock 70kD protein 9B (mortalin-2), clone MGC:8684, mRNA, complete cds. /FEA=mRNA /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:12653414 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 BC000478 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200692_s_at NM_004134 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004134.1 /DEF=Homo sapiens heat shock 70kD protein 9B (mortalin-2) (HSPA9B), mRNA. /FEA=mRNA /GEN=HSPA9B /PROD=heat shock 70kD protein 9B (mortalin-2) /DB_XREF=gi:4758569 /UG=Hs.3069 heat shock 70kD protein 9B (mortalin-2) /FL=gb:BC000478.1 gb:L15189.1 gb:NM_004134.1 NM_004134 heat shock 70kDa protein 9 (mortalin) HSPA9 3313 NM_004134 0006457 // protein folding // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200693_at NM_006826 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006826.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ), mRNA. /FEA=mRNA /GEN=YWHAQ /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, theta polypeptide /DB_XREF=gi:5803226 /UG=Hs.74405 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, theta polypeptide /FL=gb:NM_006826.1 NM_006826 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide YWHAQ 10971 NM_006826 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200694_s_at NM_020414 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_020414.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 (DDX24), mRNA. /FEA=mRNA /GEN=DDX24 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /DB_XREF=gi:13787212 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1 NM_020414 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 DDX24 57062 NM_020414 0007165 // signal transduction // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0007338 // single fertilization // traceable author statement /// 0007339 // binding of sperm to zona pellucida // inferred from electronic annotation /// 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008603 // cAMP-dependent protein kinase regulator activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200695_at NM_014225 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014225.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (PPP2R1A), mRNA. /FEA=mRNA /GEN=PPP2R1A /PROD=protein phosphatase 2 (formerly 2A), regulatorysubunit A (PR 65), alpha isoform /DB_XREF=gi:7657474 /UG=Hs.173902 protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform /FL=gb:J02902.1 gb:NM_014225.1 NM_014225 protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform PPP2R1A 5518 NM_014225 0000188 // inactivation of MAPK activity // non-traceable author statement /// 0006275 // regulation of DNA replication // non-traceable author statement /// 0006461 // protein complex assembly // traceable author statement /// 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0006672 // ceramide metabolic process // non-traceable author statement /// 0006917 // induction of apoptosis // traceable author statement /// 0008380 // RNA splicing // non-traceable author statement /// 0010033 // response to organic substance // non-traceable author statement /// 0019932 // second-messenger-mediated signaling // non-traceable author statement /// 0030111 // regulation of Wnt receptor signaling pathway // non-traceable author statement /// 0030155 // regulation of cell adhesion // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0040008 // regulation of growth // non-traceable author statement /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // non-traceable author statement /// 0045449 // regulation of transcription // non-traceable author statement /// 0045595 // regulation of cell differentiation // non-traceable author statement 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0005625 // soluble fraction // non-traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005739 // mitochondrion // non-traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0015630 // microtubule cytoskeleton // non-traceable author statement /// 0016020 // membrane // non-traceable author statement 0003823 // antigen binding // inferred from physical interaction /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008601 // protein phosphatase type 2A regulator activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200696_s_at NM_000177 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000177.1 /DEF=Homo sapiens gelsolin (amyloidosis, Finnish type) (GSN), mRNA. /FEA=mRNA /GEN=GSN /PROD=gelsolin (amyloidosis, Finnish type) /DB_XREF=gi:4504164 /UG=Hs.290070 gelsolin (amyloidosis, Finnish type) /FL=gb:NM_000177.1 NM_000177 gelsolin (amyloidosis, Finnish type) GSN 2934 NM_000177 /// NM_001127662 /// NM_001127663 /// NM_001127664 /// NM_001127665 /// NM_001127666 /// NM_001127667 /// NM_198252 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030041 // actin filament polymerization // inferred from direct assay /// 0030041 // actin filament polymerization // inferred from sequence or structural similarity /// 0051014 // actin filament severing // inferred from direct assay /// 0051014 // actin filament severing // inferred from sequence or structural similarity /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200697_at NM_000188 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000188.1 /DEF=Homo sapiens hexokinase 1 (HK1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=HK1 /PROD=hexokinase 1 /DB_XREF=gi:4504390 /UG=Hs.118625 hexokinase 1 /FL=gb:M75126.1 gb:NM_000188.1 NM_000188 hexokinase 1 HK1 3098 NM_000188 /// NM_033496 /// NM_033497 /// NM_033498 /// NM_033500 0006096 // glycolysis // traceable author statement /// 0006096 // glycolysis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004396 // hexokinase activity // not recorded /// 0004396 // hexokinase activity // inferred from electronic annotation /// 0004396 // hexokinase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200698_at AL542253 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL542253 /FEA=EST /DB_XREF=gi:12874115 /DB_XREF=est:AL542253 /CLONE=CS0DE008YC08 (3 prime) /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 AL542253 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005046 // KDEL sequence binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200699_at BE962456 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE962456 /FEA=EST /DB_XREF=gi:11765376 /DB_XREF=est:601655751R1 /CLONE=IMAGE:3846156 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 BE962456 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005046 // KDEL sequence binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200700_s_at NM_006854 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006854.2 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2), mRNA. /FEA=mRNA /GEN=KDELR2 /PROD=KDEL receptor 2 /DB_XREF=gi:8051609 /UG=Hs.118778 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 /FL=gb:NM_006854.2 NM_006854 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 KDELR2 11014 NM_001100603 /// NM_006854 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005046 // KDEL sequence binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200701_at NM_006432 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006432.1 /DEF=Homo sapiens epididymal secretory protein (19.5kD) (HE1), mRNA. /FEA=mRNA /GEN=HE1 /PROD=epididymal secretory protein (19.5kD) /DB_XREF=gi:5453677 /UG=Hs.119529 epididymal secretory protein (19.5kD) /FL=gb:BC002532.1 gb:NM_006432.1 NM_006432 Niemann-Pick disease, type C2 NPC2 10577 NM_006432 0015914 // phospholipid transport // traceable author statement /// 0019747 // regulation of isoprenoid metabolic process // traceable author statement /// 0030301 // cholesterol transport // inferred from direct assay /// 0032366 // intracellular sterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from direct assay /// 0032367 // intracellular cholesterol transport // inferred from electronic annotation /// 0042632 // cholesterol homeostasis // inferred from direct assay /// 0046836 // glycolipid transport // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0015485 // cholesterol binding // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction 200702_s_at BG421209 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG421209 /FEA=EST /DB_XREF=gi:13327715 /DB_XREF=est:602451696F1 /CLONE=IMAGE:4590215 /UG=Hs.155986 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 24 /FL=gb:AL136886.1 gb:NM_020414.2 gb:AF214731.1 BG421209 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 DDX24 57062 NM_020414 0016070 // RNA metabolic process // non-traceable author statement 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // non-traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // non-traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200703_at NM_003746 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003746.1 /DEF=Homo sapiens dynein, cytoplasmic, light polypeptide (PIN), mRNA. /FEA=mRNA /GEN=PIN /PROD=dynein, cytoplasmic, light polypeptide /DB_XREF=gi:4505812 /UG=Hs.5120 dynein, cytoplasmic, light polypeptide /FL=gb:U32944.1 gb:NM_003746.1 NM_003746 dynein, light chain, LC8-type 1 DYNLL1 8655 NM_001037494 /// NM_001037495 /// NM_003746 0007017 // microtubule-based process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement /// 0008633 // activation of pro-apoptotic gene products // not recorded /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0042326 // negative regulation of phosphorylation // inferred from direct assay 0005624 // membrane fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005868 // cytoplasmic dynein complex // traceable author statement /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0003774 // motor activity // traceable author statement /// 0003777 // microtubule motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation 200704_at AB034747 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB034747.1 /DEF=Homo sapiens SIMPLE mRNA for small integral membrane protein of lysosomelate endosome, complete cds. /FEA=mRNA /GEN=SIMPLE /PROD=small integral membrane protein of lysosomelateendosome /DB_XREF=gi:12862475 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1 AB034747 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0050699 // WW domain binding // inferred from physical interaction 200705_s_at NM_001959 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001959.1 /DEF=Homo sapiens eukaryotic translation elongation factor 1 beta 2 (EEF1B2), mRNA. /FEA=mRNA /GEN=EEF1B2 /PROD=eukaryotic translation elongation factor 1 beta2 /DB_XREF=gi:4503476 /UG=Hs.275959 eukaryotic translation elongation factor 1 beta 2 /FL=gb:BC004931.1 gb:NM_001959.1 NM_001959 eukaryotic translation elongation factor 1 beta 2 EEF1B2 1933 NM_001037663 /// NM_001959 /// NM_021121 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // non-traceable author statement /// 0006414 // translational elongation // inferred from electronic annotation 0005829 // cytosol // not recorded /// 0005853 // eukaryotic translation elongation factor 1 complex // non-traceable author statement /// 0005853 // eukaryotic translation elongation factor 1 complex // inferred from electronic annotation 0003746 // translation elongation factor activity // non-traceable author statement /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200706_s_at NM_004862 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004862.1 /DEF=Homo sapiens LPS-induced TNF-alpha factor (PIG7), mRNA. /FEA=mRNA /GEN=PIG7 /PROD=LPS-induced TNF-alpha factor /DB_XREF=gi:4758913 /UG=Hs.76507 LPS-induced TNF-alpha factor /FL=gb:AB034747.1 gb:U77396.1 gb:AF010312.1 gb:NM_004862.1 NM_004862 lipopolysaccharide-induced TNF factor LITAF 9516 NM_001136472 /// NM_001136473 /// NM_004862 /// NR_024320 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0050699 // WW domain binding // inferred from physical interaction 200707_at NM_002743 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002743.1 /DEF=Homo sapiens protein kinase C substrate 80K-H (PRKCSH), mRNA. /FEA=mRNA /GEN=PRKCSH /PROD=protein kinase C substrate 80K-H /DB_XREF=gi:4506076 /UG=Hs.1432 protein kinase C substrate 80K-H /FL=gb:J03075.1 gb:NM_002743.1 gb:AF144075.1 NM_002743 protein kinase C substrate 80K-H PRKCSH 5589 NM_001001329 /// NM_002743 0007243 // protein kinase cascade // non-traceable author statement 0005622 // intracellular // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0017177 // alpha-glucosidase II complex // inferred from electronic annotation 0004558 // alpha-glucosidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 200708_at NM_002080 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002080.1 /DEF=Homo sapiens glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) (GOT2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=GOT2 /PROD=aspartate aminotransferase 2 precursor /DB_XREF=gi:4504068 /UG=Hs.170197 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) /FL=gb:BC000525.1 gb:M22632.1 gb:NM_002080.1 NM_002080 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) GOT2 2806 NM_002080 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0006532 // aspartate biosynthetic process // inferred from electronic annotation /// 0006533 // aspartate catabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0009058 // biosynthetic process // inferred from electronic annotation /// 0015908 // fatty acid transport // inferred from expression pattern /// 0019550 // glutamate catabolic process to aspartate // inferred from electronic annotation /// 0019551 // glutamate catabolic process to 2-oxoglutarate // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004069 // aspartate transaminase activity // not recorded /// 0004069 // aspartate transaminase activity // inferred from direct assay /// 0004069 // aspartate transaminase activity // inferred from electronic annotation /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016769 // transferase activity, transferring nitrogenous groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 200709_at NM_000801 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000801.1 /DEF=Homo sapiens FK506-binding protein 1A (12kD) (FKBP1A), mRNA. /FEA=mRNA /GEN=FKBP1A /PROD=FK506-binding protein 1A (12kD) /DB_XREF=gi:4503724 /UG=Hs.752 FK506-binding protein 1A (12kD) /FL=gb:BC001925.1 gb:M34539.1 gb:NM_000801.1 NM_000801 FK506 binding protein 1A, 12kDa FKBP1A 2280 NM_000801 /// NM_054014 0003007 // heart morphogenesis // inferred from sequence or structural similarity /// 0006457 // protein folding // inferred from electronic annotation /// 0006457 // protein folding // non-traceable author statement /// 0006458 // 'de novo' protein folding // traceable author statement /// 0022417 // protein maturation via protein folding // traceable author statement /// 0032513 // negative regulation of protein phosphatase type 2B activity // inferred from direct assay /// 0042026 // protein refolding // traceable author statement /// 0042110 // T cell activation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0050776 // regulation of immune response // inferred from mutant phenotype /// 0055010 // ventricular cardiac muscle morphogenesis // inferred from sequence or structural similarity /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from direct assay /// 0060314 // regulation of ryanodine-sensitive calcium-release channel activity // inferred from sequence or structural similarity /// 0060347 // heart trabecula formation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0014802 // terminal cisterna // inferred from sequence or structural similarity 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from direct assay /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0004872 // receptor activity // traceable author statement /// 0005024 // transforming growth factor beta receptor activity // traceable author statement /// 0005219 // ryanodine-sensitive calcium-release channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200710_at NM_000018 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000018.1 /DEF=Homo sapiens acyl-Coenzyme A dehydrogenase, very long chain (ACADVL), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACADVL /PROD=acyl-Coenzyme A dehydrogenase, very long chainprecursor /DB_XREF=gi:4557234 /UG=Hs.82208 acyl-Coenzyme A dehydrogenase, very long chain /FL=gb:D43682.1 gb:BC000399.1 gb:NM_000018.1 NM_000018 acyl-Coenzyme A dehydrogenase, very long chain ACADVL 37 NM_000018 /// NM_001033859 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0015980 // energy derivation by oxidation of organic compounds // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003995 // acyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004466 // long-chain-acyl-CoA dehydrogenase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // FAD binding // inferred from electronic annotation 200711_s_at NM_003197 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003197.2 /DEF=Homo sapiens transcription elongation factor B (SIII), polypeptide 1-like (TCEB1L), mRNA. /FEA=mRNA /GEN=TCEB1L /PROD=transcription elongation factor B polypeptide1-like /DB_XREF=gi:6006030 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 NM_003197 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0019005 // SCF ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200712_s_at AI633566 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI633566 /FEA=EST /DB_XREF=gi:4684896 /DB_XREF=est:th68f09.x1 /CLONE=IMAGE:2123849 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1 AI633566 microtubule-associated protein, RP/EB family, member 1 MAPRE1 22919 NM_012325 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 200713_s_at NM_012325 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012325.1 /DEF=Homo sapiens microtubule-associated protein, RPEB family, member 1 (MAPRE1), mRNA. /FEA=mRNA /GEN=MAPRE1 /PROD=microtubule-associated protein, RPEB family,member 1 /DB_XREF=gi:6912493 /UG=Hs.234279 microtubule-associated protein, RPEB family, member 1 /FL=gb:NM_012325.1 gb:U24166.1 NM_012325 microtubule-associated protein, RP/EB family, member 1 MAPRE1 22919 NM_012325 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0031115 // negative regulation of microtubule polymerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // inferred from electronic annotation /// 0030981 // cortical microtubule cytoskeleton // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // traceable author statement /// 0051010 // microtubule plus-end binding // inferred from direct assay 200714_x_at NM_006812 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006812.1 /DEF=Homo sapiens amplified in osteosarcoma (OS-9), mRNA. /FEA=mRNA /GEN=OS-9 /PROD=amplified in osteosarcoma /DB_XREF=gi:5803108 /UG=Hs.76228 amplified in osteosarcoma /FL=gb:U41635.1 gb:AB002806.1 gb:NM_006812.1 NM_006812 amplified in osteosarcoma OS9 10956 NM_001017956 /// NM_001017957 /// NM_001017958 /// NM_006812 0005625 // soluble fraction // traceable author statement 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200715_x_at BC000514 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000514.1 /DEF=Homo sapiens, ribosomal protein L13a, clone MGC:8547, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L13a /DB_XREF=gi:12653484 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1 BC000514 ribosomal protein L13a RPL13A 23521 NM_012423 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement 200716_x_at NM_012423 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012423.1 /DEF=Homo sapiens ribosomal protein L13a (RPL13A), mRNA. /FEA=mRNA /GEN=RPL13A /PROD=ribosomal protein L13a /DB_XREF=gi:6912633 /UG=Hs.119122 ribosomal protein L13a /FL=gb:BC000514.1 gb:NM_012423.1 NM_012423 ribosomal protein L13a RPL13A 23521 NM_012423 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0015934 // large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement 200717_x_at NM_000971 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000971.1 /DEF=Homo sapiens ribosomal protein L7 (RPL7), mRNA. /FEA=mRNA /GEN=RPL7 /PROD=ribosomal protein L7 /DB_XREF=gi:4506658 /UG=Hs.153 ribosomal protein L7 /FL=gb:L16558.1 gb:NM_000971.1 NM_000971 ribosomal protein L7 RPL7 6129 NM_000971 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015934 // large ribosomal subunit // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from physical interaction 200718_s_at AA927664 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA927664 /FEA=EST /DB_XREF=gi:3076484 /DB_XREF=est:om71h10.s1 /CLONE=IMAGE:1552675 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 AA927664 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0019005 // SCF ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200719_at BE964043 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE964043 /FEA=EST /DB_XREF=gi:11767371 /DB_XREF=est:601657616R1 /CLONE=IMAGE:3875955 /UG=Hs.171626 transcription elongation factor B (SIII), polypeptide 1-like /FL=gb:NM_003197.2 BE964043 S-phase kinase-associated protein 1 SKP1 6500 NM_006930 /// NM_170679 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0019005 // SCF ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200720_s_at AL532341 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL532341 /FEA=EST /DB_XREF=gi:12795834 /DB_XREF=est:AL532341 /CLONE=CS0DM014YJ21 (5 prime) /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2 AL532341 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) ACTR1A 10121 NM_005736 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200721_s_at NM_005736 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005736.2 /DEF=Homo sapiens ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) (ACTR1A), mRNA. /FEA=mRNA /GEN=ACTR1A /PROD=actin-related protein 1A /DB_XREF=gi:13325058 /UG=Hs.153961 ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) /FL=gb:BC000693.1 gb:NM_005736.2 NM_005736 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) ACTR1A 10121 NM_005736 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // traceable author statement /// 0005875 // microtubule associated complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200722_s_at BG258784 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG258784 /FEA=EST /DB_XREF=gi:12768600 /DB_XREF=est:602378049F1 /CLONE=IMAGE:4508820 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1 BG258784 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200723_s_at NM_005898 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005898.1 /DEF=Homo sapiens membrane component, chromosome 11, surface marker 1 (M11S1), mRNA. /FEA=mRNA /GEN=M11S1 /PROD=membrane component, chromosome 11, surfacemarker 1 /DB_XREF=gi:5174502 /UG=Hs.278672 membrane component, chromosome 11, surface marker 1 /FL=gb:BC001731.1 gb:NM_005898.1 NM_005898 cell cycle associated protein 1 CAPRIN1 4076 NM_005898 /// NM_203364 0005737 // cytoplasm // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200724_at BC003358 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003358.1 /DEF=Homo sapiens, ribosomal protein L10, clone MGC:5189, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein L10 /DB_XREF=gi:13097176 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1 BC003358 ribosomal protein L10 RPL10 6134 NM_006013 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200725_x_at NM_006013 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006013.1 /DEF=Homo sapiens ribosomal protein L10 (RPL10), mRNA. /FEA=mRNA /GEN=RPL10 /PROD=ribosomal protein L10 /DB_XREF=gi:5174430 /UG=Hs.29797 ribosomal protein L10 /FL=gb:BC003358.1 gb:M73791.1 gb:M64241.1 gb:NM_006013.1 NM_006013 ribosomal protein L10 RPL10 6134 NM_006013 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200726_at NM_002710 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002710.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, gamma isoform (PPP1CC), mRNA. /FEA=mRNA /GEN=PPP1CC /PROD=protein phosphatase 1, catalytic subunit, gammaisoform /DB_XREF=gi:4506006 /UG=Hs.79081 protein phosphatase 1, catalytic subunit, gamma isoform /FL=gb:NM_002710.1 NM_002710 protein phosphatase 1, catalytic subunit, gamma isoform PPP1CC 5501 NM_002710 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200727_s_at AA699583 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA699583 /FEA=EST /DB_XREF=gi:2703730 /DB_XREF=est:zi42g07.s1 /CLONE=IMAGE:433500 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 AA699583 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cell motion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200728_at BE566290 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE566290 /FEA=EST /DB_XREF=gi:9810010 /DB_XREF=est:601339864F1 /CLONE=IMAGE:3682406 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 BE566290 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cell motion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200729_s_at NM_005722 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005722.1 /DEF=Homo sapiens ARP2 (actin-related protein 2, yeast) homolog (ACTR2), mRNA. /FEA=mRNA /GEN=ACTR2 /PROD=ARP2 (actin-related protein 2, yeast) homolog /DB_XREF=gi:5031570 /UG=Hs.42915 ARP2 (actin-related protein 2, yeast) homolog /FL=gb:AF006082.1 gb:NM_005722.1 NM_005722 ARP2 actin-related protein 2 homolog (yeast) ACTR2 10097 NM_001005386 /// NM_005722 0006928 // cell motion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200730_s_at BF576710 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF576710 /FEA=EST /DB_XREF=gi:11650422 /DB_XREF=est:602135085F1 /CLONE=IMAGE:4290141 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 BF576710 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200731_s_at AW165960 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW165960 /FEA=EST /DB_XREF=gi:6397485 /DB_XREF=est:xf43a12.x1 /CLONE=IMAGE:2620798 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 AW165960 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200732_s_at AL578310 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL578310 /FEA=EST /DB_XREF=gi:12942259 /DB_XREF=est:AL578310 /CLONE=CS0DK010YM06 (3 prime) /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 AL578310 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200733_s_at U48296 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U48296.1 /DEF=Homo sapiens protein tyrosine phosphatase PTPCAAX1 (hPTPCAAX1) mRNA, complete cds. /FEA=mRNA /GEN=hPTPCAAX1 /PROD=protein tyrosine phosphatase PTPCAAX1 /DB_XREF=gi:1777754 /UG=Hs.227777 protein tyrosine phosphatase type IVA, member 1 /FL=gb:U48296.1 gb:NM_003463.1 U48296 protein tyrosine phosphatase type IVA, member 1 PTP4A1 7803 NM_003463 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // non-traceable author statement /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 200734_s_at BG341906 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG341906 /FEA=EST /DB_XREF=gi:13148344 /DB_XREF=est:602463246F1 /CLONE=IMAGE:4576258 /UG=Hs.119177 ADP-ribosylation factor 3 /FL=gb:M74491.1 gb:NM_001659.1 BG341906 ADP-ribosylation factor 3 ARF3 377 NM_001659 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 200735_x_at NM_005594 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005594.1 /DEF=Homo sapiens nascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA. /FEA=mRNA /GEN=NACA /PROD=nascent-polypeptide-associated complex alphapolypeptide /DB_XREF=gi:5031930 /UG=Hs.32916 nascent-polypeptide-associated complex alpha polypeptide /FL=gb:AF054187.1 gb:NM_005594.1 NM_005594 nascent polypeptide-associated complex alpha subunit NACA 4666 NM_001113201 /// NM_001113202 /// NM_001113203 /// NM_005594 0006350 // transcription // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005854 // nascent polypeptide-associated complex // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200736_s_at NM_000581 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000581.1 /DEF=Homo sapiens glutathione peroxidase 1 (GPX1), mRNA. /FEA=mRNA /GEN=GPX1 /PROD=glutathione peroxidase 1 /DB_XREF=gi:10834975 /UG=Hs.76686 glutathione peroxidase 1 /FL=gb:NM_000581.1 gb:BC000742.1 gb:M21304.1 NM_000581 glutathione peroxidase 1 GPX1 2876 NM_000581 /// NM_201397 0000302 // response to reactive oxygen species // inferred from electronic annotation /// 0001659 // temperature homeostasis // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from mutant phenotype /// 0001885 // endothelial cell development // inferred from electronic annotation /// 0002862 // negative regulation of inflammatory response to antigenic stimulus // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triacylglycerol metabolic process // inferred from electronic annotation /// 0006749 // glutathione metabolic process // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006917 // induction of apoptosis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008631 // induction of apoptosis by oxidative stress // inferred from electronic annotation /// 0009410 // response to xenobiotic stimulus // inferred from electronic annotation /// 0009609 // response to symbiotic bacterium // inferred from electronic annotation /// 0009611 // response to wounding // inferred from electronic annotation /// 0009636 // response to toxin // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0010269 // response to selenium ion // inferred from mutant phenotype /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0014902 // myotube differentiation // inferred from electronic annotation /// 0018158 // protein amino acid oxidation // inferred from electronic annotation /// 0033194 // response to hydroperoxide // inferred from electronic annotation /// 0033599 // regulation of mammary gland epithelial cell proliferation // inferred from mutant phenotype /// 0040029 // regulation of gene expression, epigenetic // inferred from direct assay /// 0042311 // vasodilation // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from mutant phenotype /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043154 // negative regulation of caspase activity // inferred from mutant phenotype /// 0043403 // skeletal muscle regeneration // inferred from electronic annotation /// 0043523 // regulation of neuron apoptosis // inferred from electronic annotation /// 0043534 // blood vessel endothelial cell migration // inferred from electronic annotation /// 0045444 // fat cell differentiation // inferred from electronic annotation /// 0048741 // skeletal muscle fiber development // inferred from electronic annotation /// 0051450 // myoblast proliferation // inferred from electronic annotation /// 0051702 // interaction with symbiont // inferred from electronic annotation /// 0051897 // positive regulation of protein kinase B signaling cascade // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation /// 0060047 // heart contraction // inferred from electronic annotation /// 0060047 // heart contraction // inferred from mutant phenotype /// 0060055 // angiogenesis involved in wound healing // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // not recorded 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // not recorded /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0008430 // selenium binding // inferred from electronic annotation /// 0008539 // proteasome inhibitor activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from physical interaction /// 0043295 // glutathione binding // inferred by curator 200737_at NM_000291 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1 NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0006096 // glycolysis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0004618 // phosphoglycerate kinase activity // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200738_s_at NM_000291 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000291.1 /DEF=Homo sapiens phosphoglycerate kinase 1 (PGK1), mRNA. /FEA=mRNA /GEN=PGK1 /PROD=phosphoglycerate kinase 1 /DB_XREF=gi:4505762 /UG=Hs.78771 phosphoglycerate kinase 1 /FL=gb:NM_000291.1 NM_000291 phosphoglycerate kinase 1 PGK1 5230 NM_000291 0006096 // glycolysis // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from sequence or structural similarity 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // inferred from sequence or structural similarity /// 0004618 // phosphoglycerate kinase activity // inferred from electronic annotation /// 0004618 // phosphoglycerate kinase activity // traceable author statement /// 0005524 // ATP binding // inferred from sequence or structural similarity /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200739_s_at BG338532 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG338532 /FEA=EST /DB_XREF=gi:13144970 /DB_XREF=est:602436260F1 /CLONE=IMAGE:4554278 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1 BG338532 SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) SUMO3 6612 NM_006936 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200740_s_at NM_006936 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006936.1 /DEF=Homo sapiens SMT3 (suppressor of mif two 3, yeast) homolog 1 (SMT3H1), mRNA. /FEA=mRNA /GEN=SMT3H1 /PROD=SMT3 (suppressor of mif two 3, yeast) homolog 1 /DB_XREF=gi:5902095 /UG=Hs.85119 SMT3 (suppressor of mif two 3, yeast) homolog 1 /FL=gb:BC000036.1 gb:NM_006936.1 NM_006936 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) /// SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) SUMO2 /// SUMO3 6612 /// 6613 NM_001005849 /// NM_006936 /// NM_006937 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200741_s_at NM_001030 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001030.1 /DEF=Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA. /FEA=mRNA /GEN=RPS27 /PROD=ribosomal protein S27 (metallopanstimulin 1) /DB_XREF=gi:4506710 /UG=Hs.195453 ribosomal protein S27 (metallopanstimulin 1) /FL=gb:U57847.1 gb:L19739.1 gb:NM_001030.1 NM_001030 ribosomal protein S27 RPS27 6232 NM_001030 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0008283 // cell proliferation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200742_s_at BG231932 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG231932 /FEA=EST /DB_XREF=gi:12727071 /DB_XREF=est:naf34b12.x1 /CLONE=IMAGE:4142926 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2 BG231932 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0030163 // protein catabolic process // non-traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005625 // soluble fraction // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 200743_s_at NM_000391 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000391.2 /DEF=Homo sapiens ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) (CLN2), mRNA. /FEA=mRNA /GEN=CLN2 /PROD=ceroid-lipofuscinosis, neuronal 2, lateinfantile (Jansky-Bielschowsky disease) /DB_XREF=gi:5597012 /UG=Hs.20478 ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease) /FL=gb:AF017456.1 gb:NM_000391.2 NM_000391 tripeptidyl peptidase I TPP1 1200 NM_000391 0006508 // proteolysis // inferred from mutant phenotype /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0030163 // protein catabolic process // non-traceable author statement /// 0043171 // peptide catabolic process // inferred from mutant phenotype /// 0045453 // bone resorption // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005625 // soluble fraction // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from mutant phenotype /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from direct assay /// 0004175 // endopeptidase activity // inferred from mutant phenotype /// 0004175 // endopeptidase activity // inferred from sequence or structural similarity /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from mutant phenotype /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from direct assay /// 0008240 // tripeptidyl-peptidase activity // inferred from mutant phenotype /// 0008240 // tripeptidyl-peptidase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 200744_s_at AI741124 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI741124 /FEA=EST /DB_XREF=gi:5109412 /DB_XREF=est:wg19c04.x1 /CLONE=IMAGE:2365542 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 AI741124 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_002074 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007200 // G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) // inferred from electronic annotation /// 0007204 // elevation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009755 // hormone-mediated signaling // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 200745_s_at AF070603 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF070603.1 /DEF=Homo sapiens clone 24584 beta-subunit signal transducing proteins GSGI mRNA, partial cds. /FEA=mRNA /PROD=beta-subunit signal transducing proteins GSGI /DB_XREF=gi:3387983 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 AF070603 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_002074 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007200 // G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) // inferred from electronic annotation /// 0007204 // elevation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009755 // hormone-mediated signaling // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 200746_s_at NM_002074 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002074.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1), mRNA. /FEA=mRNA /GEN=GNB1 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 1 /DB_XREF=gi:11321584 /UG=Hs.215595 guanine nucleotide binding protein (G protein), beta polypeptide 1 /FL=gb:NM_002074.1 gb:BC004186.1 NM_002074 guanine nucleotide binding protein (G protein), beta polypeptide 1 GNB1 2782 NM_002074 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007200 // G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) // inferred from electronic annotation /// 0007204 // elevation of cytosolic calcium ion concentration // inferred from electronic annotation /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // traceable author statement /// 0007265 // Ras protein signal transduction // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009755 // hormone-mediated signaling // not recorded /// 0050909 // sensory perception of taste // inferred from electronic annotation 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0031702 // type 1 angiotensin receptor binding // inferred from electronic annotation 200747_s_at NM_006185 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006185.1 /DEF=Homo sapiens nuclear mitotic apparatus protein 1 (NUMA1), mRNA. /FEA=mRNA /GEN=NUMA1 /PROD=nuclear mitotic apparatus protein 1 /DB_XREF=gi:5453819 /UG=Hs.301512 nuclear mitotic apparatus protein 1 /FL=gb:NM_006185.1 NM_006185 nuclear mitotic apparatus protein 1 NUMA1 4926 NM_006185 0000090 // mitotic anaphase // traceable author statement /// 0006997 // nucleus organization // traceable author statement 0000922 // spindle pole // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005819 // spindle // traceable author statement /// 0005876 // spindle microtubule // traceable author statement 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200748_s_at NM_002032 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002032.1 /DEF=Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA. /FEA=mRNA /GEN=FTH1 /PROD=ferritin, heavy polypeptide 1 /DB_XREF=gi:4503794 /UG=Hs.62954 ferritin, heavy polypeptide 1 /FL=gb:BC000857.1 gb:BC001399.1 gb:M11146.1 gb:M12937.1 gb:M97164.1 gb:NM_002032.1 gb:L20941.1 NM_002032 ferritin, heavy polypeptide 1 FTH1 2495 NM_002032 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // traceable author statement /// 0006880 // intracellular sequestering of iron ion // traceable author statement /// 0006955 // immune response // inferred from direct assay /// 0006955 // immune response // inferred from sequence or structural similarity /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from sequence or structural similarity /// 0055114 // oxidation reduction // inferred from electronic annotation 0005886 // plasma membrane // non-traceable author statement /// 0008043 // ferritin complex // traceable author statement 0004322 // ferroxidase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005506 // iron ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008199 // ferric iron binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 200749_at BF112006 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF112006 /FEA=EST /DB_XREF=gi:10941619 /DB_XREF=est:7l37e05.x1 /CLONE=IMAGE:3523665 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2 BF112006 RAN, member RAS oncogene family RAN 5901 NM_006325 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006611 // protein export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 200750_s_at AF054183 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF054183.1 /DEF=Homo sapiens GTP binding protein mRNA, complete cds. /FEA=mRNA /PROD=GTP binding protein /DB_XREF=gi:4092053 /UG=Hs.10842 RAN, member RAS oncogene family /FL=gb:BC000852.1 gb:BC004272.1 gb:M31469.1 gb:AF052578.1 gb:AF054183.1 gb:NM_006325.2 AF054183 RAN, member RAS oncogene family RAN 5901 NM_006325 0006259 // DNA metabolic process // traceable author statement /// 0006405 // RNA export from nucleus // non-traceable author statement /// 0006611 // protein export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007067 // mitosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // non-traceable author statement 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // non-traceable author statement /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0003713 // transcription coactivator activity // non-traceable author statement /// 0003924 // GTPase activity // not recorded /// 0003924 // GTPase activity // traceable author statement /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 200751_s_at BE898861 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE898861 /FEA=EST /DB_XREF=gi:10365758 /DB_XREF=est:601682157F1 /CLONE=IMAGE:3952046 /UG=Hs.182447 heterogeneous nuclear ribonucleoprotein C (C1C2) /FL=gb:BC003394.1 gb:M16342.1 gb:NM_004500.1 BE898861 heterogeneous nuclear ribonucleoprotein C (C1/C2) HNRNPC 3183 NM_001077442 /// NM_001077443 /// NM_004500 /// NM_031314 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 200752_s_at NM_005186 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005186.2 /DEF=Homo sapiens calpain 1, (muI) large subunit (CAPN1), mRNA. /FEA=mRNA /GEN=CAPN1 /PROD=calpain 1, large subunit /DB_XREF=gi:12408655 /UG=Hs.2575 calpain 1, (muI) large subunit /FL=gb:NM_005186.2 NM_005186 calpain 1, (mu/I) large subunit CAPN1 823 NM_005186 0006508 // proteolysis // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004198 // calcium-dependent cysteine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200753_x_at BE866585 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE866585 /FEA=EST /DB_XREF=gi:10315361 /DB_XREF=est:601678773F1 /CLONE=IMAGE:3961243 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1 BE866585 splicing factor, arginine/serine-rich 2 SFRS2 6427 NM_003016 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200754_x_at NM_003016 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003016.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 2 (SFRS2), mRNA. /FEA=mRNA /GEN=SFRS2 /PROD=splicing factor, arginineserine-rich 2 /DB_XREF=gi:4506898 /UG=Hs.73965 splicing factor, arginineserine-rich 2 /FL=gb:BC000339.1 gb:BC001303.1 gb:M90104.1 gb:NM_003016.1 NM_003016 splicing factor, arginine/serine-rich 2 SFRS2 6427 NM_003016 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200755_s_at BF939365 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF939365 /FEA=EST /DB_XREF=gi:12356685 /DB_XREF=est:nad87h04.x1 /CLONE=IMAGE:3410551 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 BF939365 calumenin CALU 813 NM_001130674 /// NM_001219 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement 200756_x_at U67280 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U67280.1 /DEF=Homo sapiens calumenin mRNA, complete cds. /FEA=mRNA /PROD=calumenin /DB_XREF=gi:2809323 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 U67280 calumenin CALU 813 NM_001130674 /// NM_001219 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement 200757_s_at NM_001219 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001219.2 /DEF=Homo sapiens calumenin (CALU), mRNA. /FEA=mRNA /GEN=CALU /PROD=calumenin precursor /DB_XREF=gi:6005991 /UG=Hs.7753 calumenin /FL=gb:U67280.1 gb:AF013759.1 gb:NM_001219.2 NM_001219 calumenin CALU 813 NM_001130674 /// NM_001219 0005576 // extracellular region // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0005509 // calcium ion binding // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement 200758_s_at AI361227 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI361227 /FEA=EST /DB_XREF=gi:4112848 /DB_XREF=est:qy12a07.x1 /CLONE=IMAGE:2011764 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1 AI361227 nuclear factor (erythroid-derived 2)-like 1 NFE2L1 4779 NM_003204 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0045449 // regulation of transcription // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 200759_x_at NM_003204 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003204.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 1 (NFE2L1), mRNA. /FEA=mRNA /GEN=NFE2L1 /PROD=transcription factor 11 (basic leucine zippertype) /DB_XREF=gi:4505378 /UG=Hs.83469 nuclear factor (erythroid-derived 2)-like 1 /FL=gb:NM_003204.1 gb:U08853.1 NM_003204 nuclear factor (erythroid-derived 2)-like 1 NFE2L1 4779 NM_003204 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006783 // heme biosynthetic process // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0045449 // regulation of transcription // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003712 // transcription cofactor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 200760_s_at N92494 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N92494 /FEA=EST /DB_XREF=gi:1264803 /DB_XREF=est:zb12h11.s1 /CLONE=IMAGE:301893 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2 N92494 ADP-ribosylation-like factor 6 interacting protein 5 ARL6IP5 10550 NM_006407 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0015813 // L-glutamate transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from sequence or structural similarity /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 200761_s_at NM_006407 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006407.2 /DEF=Homo sapiens vitamin A responsive; cytoskeleton related (JWA), mRNA. /FEA=mRNA /GEN=JWA /PROD=vitamin A responsive; cytoskeleton related /DB_XREF=gi:7669496 /UG=Hs.92384 vitamin A responsive; cytoskeleton related /FL=gb:BC005143.1 gb:AF070523.1 gb:AF125530.1 gb:AF161476.1 gb:NM_006407.2 NM_006407 ADP-ribosylation-like factor 6 interacting protein 5 ARL6IP5 10550 NM_006407 0015813 // L-glutamate transport // inferred from sequence or structural similarity /// 0015813 // L-glutamate transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from sequence or structural similarity /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 200762_at NM_001386 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001386.1 /DEF=Homo sapiens dihydropyrimidinase-like 2 (DPYSL2), mRNA. /FEA=mRNA /GEN=DPYSL2 /PROD=dihydropyrimidinase-like 2 /DB_XREF=gi:4503376 /UG=Hs.173381 dihydropyrimidinase-like 2 /FL=gb:U17279.1 gb:D78013.1 gb:U97105.1 gb:NM_001386.1 NM_001386 dihydropyrimidinase-like 2 DPYSL2 1808 NM_001386 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // cell soma // inferred from electronic annotation 0004157 // dihydropyrimidinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation 200763_s_at NM_001003 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001003.1 /DEF=Homo sapiens ribosomal protein, large, P1 (RPLP1), mRNA. /FEA=mRNA /GEN=RPLP1 /PROD=ribosomal protein, large, P1 /DB_XREF=gi:4506668 /UG=Hs.177592 ribosomal protein, large, P1 /FL=gb:BC003369.1 gb:M17886.1 gb:NM_001003.1 NM_001003 ribosomal protein, large, P1 RPLP1 6176 NM_001003 /// NM_213725 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200764_s_at AI826881 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI826881 /FEA=EST /DB_XREF=gi:5447552 /DB_XREF=est:wk75f03.x1 /CLONE=IMAGE:2421245 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1 AI826881 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001903 0007155 // cell adhesion // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043297 // apical junction assembly // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 200765_x_at NM_001903 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001903.1 /DEF=Homo sapiens catenin (cadherin-associated protein), alpha 1 (102kD) (CTNNA1), mRNA. /FEA=mRNA /GEN=CTNNA1 /PROD=catenin (cadherin-associated protein), alpha 1(102kD) /DB_XREF=gi:4503126 /UG=Hs.178452 catenin (cadherin-associated protein), alpha 1 (102kD) /FL=gb:L23805.1 gb:NM_001903.1 NM_001903 catenin (cadherin-associated protein), alpha 1, 102kDa CTNNA1 1495 NM_001903 0007155 // cell adhesion // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007163 // establishment or maintenance of cell polarity // inferred from electronic annotation /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043297 // apical junction assembly // non-traceable author statement /// 0043297 // apical junction assembly // inferred from electronic annotation /// 0045880 // positive regulation of smoothened signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005915 // zonula adherens // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from physical interaction /// 0045296 // cadherin binding // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 200766_at NM_001909 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001909.1 /DEF=Homo sapiens cathepsin D (lysosomal aspartyl protease) (CTSD), mRNA. /FEA=mRNA /GEN=CTSD /PROD=cathepsin D (lysosomal aspartyl protease) /DB_XREF=gi:4503142 /UG=Hs.79572 cathepsin D (lysosomal aspartyl protease) /FL=gb:M11233.1 gb:NM_001909.1 NM_001909 cathepsin D CTSD 1509 NM_001909 0006508 // proteolysis // inferred from electronic annotation /// 0009607 // response to biotic stimulus // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005764 // lysosome // non-traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004190 // aspartic-type endopeptidase activity // traceable author statement /// 0004190 // aspartic-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200767_s_at NM_014612 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014612.1 /DEF=Homo sapiens C9orf10 protein (C9orf10), mRNA. /FEA=mRNA /GEN=C9orf10 /PROD=C9orf10 protein /DB_XREF=gi:8922113 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1 NM_014612 family with sequence similarity 120A FAM120A 23196 NM_014612 200768_s_at BC001686 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001686.1 /DEF=Homo sapiens, methionine adenosyltransferase II, alpha, clone MGC:2907, mRNA, complete cds. /FEA=mRNA /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:12804546 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1 BC001686 methionine adenosyltransferase II, alpha MAT2A 4144 NM_005911 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009725 // response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // traceable author statement /// 0004478 // methionine adenosyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation 200769_s_at NM_005911 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005911.1 /DEF=Homo sapiens methionine adenosyltransferase II, alpha (MAT2A), mRNA. /FEA=mRNA /GEN=MAT2A /PROD=methionine adenosyltransferase II, alpha /DB_XREF=gi:5174528 /UG=Hs.77502 methionine adenosyltransferase II, alpha /FL=gb:BC001686.1 gb:BC001854.1 gb:NM_005911.1 NM_005911 methionine adenosyltransferase II, alpha MAT2A 4144 NM_005911 0006556 // S-adenosylmethionine biosynthetic process // inferred from electronic annotation /// 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009725 // response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004478 // methionine adenosyltransferase activity // traceable author statement /// 0004478 // methionine adenosyltransferase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050897 // cobalt ion binding // inferred from electronic annotation 200770_s_at J03202 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03202.1 /DEF=Human laminin B2 chain mRNA, complete cds. /FEA=mRNA /GEN=LAMB2 /DB_XREF=gi:186916 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2 J03202 laminin, gamma 1 (formerly LAMB2) LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005604 // basement membrane // traceable author statement /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0043259 // laminin-10 complex // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 200771_at NM_002293 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002293.2 /DEF=Homo sapiens laminin, gamma 1 (formerly LAMB2) (LAMC1), mRNA. /FEA=mRNA /GEN=LAMC1 /PROD=laminin, gamma 1 precursor /DB_XREF=gi:9845497 /UG=Hs.214982 laminin, gamma 1 (formerly LAMB2) /FL=gb:J03202.1 gb:NM_002293.2 NM_002293 laminin, gamma 1 (formerly LAMB2) LAMC1 3915 NM_002293 0006461 // protein complex assembly // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007492 // endoderm development // traceable author statement /// 0016477 // cell migration // inferred from mutant phenotype /// 0022617 // extracellular matrix disassembly // inferred from mutant phenotype /// 0031581 // hemidesmosome assembly // inferred from mutant phenotype /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // inferred from electronic annotation /// 0005604 // basement membrane // traceable author statement /// 0005605 // basal lamina // inferred from electronic annotation /// 0005606 // laminin-1 complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031012 // extracellular matrix // inferred from direct assay /// 0031012 // extracellular matrix // inferred from electronic annotation /// 0043259 // laminin-10 complex // inferred from electronic annotation 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005515 // protein binding // inferred from electronic annotation 200772_x_at BF686442 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF686442 /FEA=EST /DB_XREF=gi:11971850 /DB_XREF=est:602143234F1 /CLONE=IMAGE:4304193 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1 BF686442 prothymosin, alpha PTMA 5757 NM_001099285 /// NM_002823 0006350 // transcription // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 200773_x_at NM_002823 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002823.1 /DEF=Homo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA. /FEA=mRNA /GEN=PTMA /PROD=prothymosin, alpha (gene sequence 28) /DB_XREF=gi:4506276 /UG=Hs.250655 prothymosin, alpha (gene sequence 28) /FL=gb:BC003510.1 gb:M26708.1 gb:M14630.1 gb:NM_002823.1 NM_002823 prothymosin, alpha PTMA 5757 NM_001099285 /// NM_002823 0006350 // transcription // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 200774_at BE963765 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE963765 /FEA=EST /DB_XREF=gi:11767182 /DB_XREF=est:601657412R1 /CLONE=IMAGE:3875738 /UG=Hs.76666 C9orf10 protein /FL=gb:AF214737.1 gb:NM_014612.1 BE963765 family with sequence similarity 120A FAM120A 23196 NM_014612 200775_s_at BC000355 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000355.1 /DEF=Homo sapiens, heterogeneous nuclear ribonucleoprotein K, clone MGC:8660, mRNA, complete cds. /FEA=mRNA /PROD=heterogeneous nuclear ribonucleoprotein K /DB_XREF=gi:12653174 /UG=Hs.129548 heterogeneous nuclear ribonucleoprotein K /FL=gb:BC000355.1 gb:NM_002140.1 BC000355 heterogeneous nuclear ribonucleoprotein K HNRNPK 3190 NM_002140 /// NM_031262 /// NM_031263 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200776_s_at AL518328 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL518328 /FEA=EST /DB_XREF=gi:12781821 /DB_XREF=est:AL518328 /CLONE=CS0DA009YK18 (3 prime) /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1 AL518328 basic leucine zipper and W2 domains 1 BZW1 9689 NM_014670 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation 200777_s_at NM_014670 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014670.1 /DEF=Homo sapiens KIAA0005 gene product (KIAA0005), mRNA. /FEA=mRNA /GEN=KIAA0005 /PROD=KIAA0005 gene product /DB_XREF=gi:7661849 /UG=Hs.155291 KIAA0005 gene product /FL=gb:D13630.1 gb:NM_014670.1 NM_014670 basic leucine zipper and W2 domains 1 BZW1 9689 NM_014670 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation 200778_s_at AI191427 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI191427 /FEA=EST /DB_XREF=gi:3742636 /DB_XREF=est:qe48g03.x1 /CLONE=IMAGE:1742260 /UG=Hs.155595 neural precursor cell expressed, developmentally down-regulated 5 /FL=gb:D28540.1 gb:NM_004404.1 gb:D63878.1 AI191427 septin 2 SEPT2 4735 NM_001008491 /// NM_001008492 /// NM_004404 /// NM_006155 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 200779_at NM_001675 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001675.1 /DEF=Homo sapiens activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4), mRNA. /FEA=mRNA /GEN=ATF4 /PROD=activating transcription factor 4 /DB_XREF=gi:4502264 /UG=Hs.181243 activating transcription factor 4 (tax-responsive enhancer element B67) /FL=gb:M86842.1 gb:NM_001675.1 NM_001675 activating transcription factor 4 (tax-responsive enhancer element B67) ATF4 468 NM_001675 /// NM_182810 0006094 // gluconeogenesis // inferred from sequence or structural similarity /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006520 // amino acid metabolic process // traceable author statement /// 0006950 // response to stress // inferred from expression pattern /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from sequence or structural similarity /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003704 // specific RNA polymerase II transcription factor activity // inferred from sequence or structural similarity /// 0003704 // specific RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0008022 // protein C-terminus binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from mutant phenotype /// 0016563 // transcription activator activity // inferred from sequence or structural similarity /// 0016563 // transcription activator activity // non-traceable author statement /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation /// 0050811 // GABA receptor binding // inferred from electronic annotation 200780_x_at NM_000516 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000516.2 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1), mRNA. /FEA=mRNA /GEN=GNAS1 /PROD=guanine nucleotide binding protein (G protein),alpha stimulating activity polypeptide 1 /DB_XREF=gi:8659565 /UG=Hs.273385 guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 /FL=gb:BC002722.1 gb:AF088185.1 gb:NM_000516.2 NM_000516 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007189 // G-protein signaling, adenylate cyclase activating pathway // inferred from electronic annotation /// 0007189 // G-protein signaling, adenylate cyclase activating pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007565 // female pregnancy // non-traceable author statement /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009755 // hormone-mediated signaling // not recorded /// 0046907 // intracellular transport // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031224 // intrinsic to membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005525 // GTP binding // non-traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200781_s_at NM_001019 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001019.1 /DEF=Homo sapiens ribosomal protein S15a (RPS15A), mRNA. /FEA=mRNA /GEN=RPS15A /PROD=ribosomal protein S15a /DB_XREF=gi:4506688 /UG=Hs.2953 ribosomal protein S15a /FL=gb:BC001697.1 gb:NM_001019.1 NM_001019 ribosomal protein S15a RPS15A 6210 NM_001019 /// NM_001030009 0006396 // RNA processing // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from electronic annotation /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0009615 // response to virus // inferred from direct assay /// 0045787 // positive regulation of cell cycle // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000175 // 3'-5'-exoribonuclease activity // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0004654 // polyribonucleotide nucleotidyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 200782_at NM_001154 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001154.2 /DEF=Homo sapiens annexin A5 (ANXA5), mRNA. /FEA=mRNA /GEN=ANXA5 /PROD=annexin V /DB_XREF=gi:4809273 /UG=Hs.300711 annexin A5 /FL=gb:BC001429.1 gb:BC004993.1 gb:M18366.1 gb:J03745.1 gb:M21731.1 gb:M19384.1 gb:D00172.1 gb:NM_001154.2 NM_001154 annexin A5 ANXA5 308 NM_001154 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007596 // blood coagulation // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 0050819 // negative regulation of coagulation // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0043499 // eukaryotic cell surface binding // inferred from electronic annotation 200783_s_at NM_005563 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005563.2 /DEF=Homo sapiens leukemia-associated phosphoprotein p18 (stathmin) (LAP18), mRNA. /FEA=mRNA /GEN=LAP18 /PROD=leukemia-associated phosphoprotein p18 /DB_XREF=gi:13518023 /UG=Hs.81915 leukemia-associated phosphoprotein p18 (stathmin) /FL=gb:NM_005563.2 gb:J04991.1 NM_005563 stathmin 1/oncoprotein 18 STMN1 3925 NM_005563 /// NM_203399 /// NM_203401 0007019 // microtubule depolymerization // inferred from direct assay /// 0007052 // mitotic spindle organization // inferred from direct assay /// 0007165 // signal transduction // non-traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0031115 // negative regulation of microtubule polymerization // inferred from electronic annotation /// 0051272 // positive regulation of cell motion // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0015631 // tubulin binding // inferred from direct assay 200784_s_at BF304759 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF304759 /FEA=EST /DB_XREF=gi:11251657 /DB_XREF=est:601888339F1 /CLONE=IMAGE:4122417 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1 BF304759 similar to low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /// low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) LOC100134190 /// LRP1 100134190 /// 4035 NM_002332 /// XR_037669 0006629 // lipid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030178 // negative regulation of Wnt receptor signaling pathway // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008034 // lipoprotein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200785_s_at NM_002332 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002332.1 /DEF=Homo sapiens low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) (LRP1), mRNA. /FEA=mRNA /GEN=LRP1 /PROD=low density lipoprotein-related protein 1(alpha-2-macroglobulin receptor) /DB_XREF=gi:4758685 /UG=Hs.89137 low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /FL=gb:NM_002332.1 NM_002332 similar to low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) /// low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) LOC100134190 /// LRP1 100134190 /// 4035 NM_002332 /// XR_037669 0006629 // lipid metabolic process // traceable author statement /// 0006897 // endocytosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0030178 // negative regulation of Wnt receptor signaling pathway // inferred from electronic annotation /// 0043277 // apoptotic cell clearance // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008034 // lipoprotein binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200786_at NM_002799 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002799.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7), mRNA. /FEA=mRNA /GEN=PSMB7 /PROD=proteasome (prosome, macropain) subunit, betatype, 7 /DB_XREF=gi:4506202 /UG=Hs.118065 proteasome (prosome, macropain) subunit, beta type, 7 /FL=gb:BC000509.1 gb:D38048.1 gb:NM_002799.1 NM_002799 proteasome (prosome, macropain) subunit, beta type, 7 PSMB7 5695 NM_002799 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200787_s_at BC002426 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002426.1 /DEF=Homo sapiens, phosphoprotein enriched in astrocytes 15, clone MGC:1685, mRNA, complete cds. /FEA=mRNA /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:12803230 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1 BC002426 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from direct assay /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from direct assay /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005351 // sugar:hydrogen symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200788_s_at NM_003768 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003768.1 /DEF=Homo sapiens phosphoprotein enriched in astrocytes 15 (PEA15), mRNA. /FEA=mRNA /GEN=PEA15 /PROD=phosphoprotein enriched in astrocytes 15 /DB_XREF=gi:4505704 /UG=Hs.194673 phosphoprotein enriched in astrocytes 15 /FL=gb:BC002426.1 gb:NM_003768.1 NM_003768 phosphoprotein enriched in astrocytes 15 PEA15 8682 NM_003768 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from direct assay /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from direct assay /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement 0005351 // sugar:hydrogen symporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200789_at NM_001398 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001398.1 /DEF=Homo sapiens enoyl Coenzyme A hydratase 1, peroxisomal (ECH1), mRNA. /FEA=mRNA /GEN=ECH1 /PROD=peroxisomal enoyl-coenzyme A hydratase-likeprotein /DB_XREF=gi:4503446 /UG=Hs.196176 enoyl Coenzyme A hydratase 1, peroxisomal /FL=gb:NM_001398.1 gb:U16660.1 NM_001398 enoyl Coenzyme A hydratase 1, peroxisomal ECH1 1891 NM_001398 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005777 // peroxisome // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation 200790_at NM_002539 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002539.1 /DEF=Homo sapiens ornithine decarboxylase 1 (ODC1) mRNA. /FEA=mRNA /GEN=ODC1 /PROD=ornithine decarboxylase 1 /DB_XREF=gi:4505488 /UG=Hs.75212 ornithine decarboxylase 1 /FL=gb:M16650.1 gb:NM_002539.1 NM_002539 ornithine decarboxylase 1 ODC1 4953 NM_002539 0001822 // kidney development // inferred from electronic annotation /// 0006596 // polyamine biosynthetic process // non-traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004586 // ornithine decarboxylase activity // traceable author statement /// 0004586 // ornithine decarboxylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 200791_s_at NM_003870 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003870.1 /DEF=Homo sapiens IQ motif containing GTPase activating protein 1 (IQGAP1), mRNA. /FEA=mRNA /GEN=IQGAP1 /PROD=IQ motif containing GTPase activating protein 1 /DB_XREF=gi:4506786 /UG=Hs.1742 IQ motif containing GTPase activating protein 1 /FL=gb:NM_003870.1 gb:L33075.1 NM_003870 IQ motif containing GTPase activating protein 1 IQGAP1 8826 NM_003870 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005884 // actin filament // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation 0005095 // GTPase inhibitor activity // traceable author statement /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // traceable author statement /// 0005099 // Ras GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0005516 // calmodulin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation 200792_at NM_001469 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001469.1 /DEF=Homo sapiens thyroid autoantigen 70kD (Ku antigen) (G22P1), mRNA. /FEA=mRNA /GEN=G22P1 /PROD=thyroid autoantigen 70kD (Ku antigen) /DB_XREF=gi:4503840 /UG=Hs.197345 thyroid autoantigen 70kD (Ku antigen) /FL=gb:J04611.1 gb:M32865.1 gb:J04607.1 gb:NM_001469.1 NM_001469 X-ray repair complementing defective repair in Chinese hamster cells 6 XRCC6 2547 NM_001469 0006266 // DNA ligation // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006303 // double-strand break repair via nonhomologous end joining // traceable author statement /// 0006303 // double-strand break repair via nonhomologous end joining // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0019047 // provirus integration // not recorded /// 0019059 // initiation of viral infection // not recorded /// 0033151 // V(D)J recombination // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay /// 0050769 // positive regulation of neurogenesis // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005958 // DNA-dependent protein kinase complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004003 // ATP-dependent DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 200793_s_at NM_001098 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001098.1 /DEF=Homo sapiens aconitase 2, mitochondrial (ACO2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ACO2 /PROD=aconitase 2 /DB_XREF=gi:4501866 /UG=Hs.300463 aconitase 2, mitochondrial /FL=gb:U80040.1 gb:NM_001098.1 NM_001098 aconitase 2, mitochondrial ACO2 50 NM_001098 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006099 // tricarboxylic acid cycle // inferred from direct assay /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006101 // citrate metabolic process // inferred from direct assay /// 0006101 // citrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded 0003994 // aconitate hydratase activity // not recorded /// 0003994 // aconitate hydratase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from direct assay /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005506 // iron ion binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation /// 0051539 // 4 iron, 4 sulfur cluster binding // inferred from electronic annotation 200794_x_at NM_014764 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014764.1 /DEF=Homo sapiens DAZ associated protein 2 (DAZAP2), mRNA. /FEA=mRNA /GEN=DAZAP2 /PROD=DAZ associated protein 2 /DB_XREF=gi:7661885 /UG=Hs.75416 DAZ associated protein 2 /FL=gb:BC002334.1 gb:D31767.1 gb:NM_014764.1 NM_014764 DAZ associated protein 2 DAZAP2 9802 NM_001136264 /// NM_001136266 /// NM_001136267 /// NM_001136268 /// NM_001136269 /// NM_014764 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0050699 // WW domain binding // inferred from physical interaction 200795_at NM_004684 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004684.1 /DEF=Homo sapiens SPARC-like 1 (mast9, hevin) (SPARCL1), mRNA. /FEA=mRNA /GEN=SPARCL1 /PROD=SPARC-like 1 /DB_XREF=gi:4758521 /UG=Hs.75445 SPARC-like 1 (mast9, hevin) /FL=gb:NM_004684.1 NM_004684 SPARC-like 1 (hevin) SPARCL1 8404 NM_001128310 /// NM_004684 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation 200796_s_at BF594446 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF594446 /FEA=EST /DB_XREF=gi:11686770 /DB_XREF=est:7i06c12.x1 /CLONE=IMAGE:3324694 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 BF594446 myeloid cell leukemia sequence 1 (BCL2-related) MCL1 4170 NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008632 // apoptotic program // traceable author statement /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200797_s_at AI275690 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI275690 /FEA=EST /DB_XREF=gi:3897964 /DB_XREF=est:qw03a03.x1 /CLONE=IMAGE:1989964 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 AI275690 myeloid cell leukemia sequence 1 (BCL2-related) MCL1 4170 NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008632 // apoptotic program // traceable author statement /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200798_x_at NM_021960 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021960.1 /DEF=Homo sapiens myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), mRNA. /FEA=mRNA /GEN=MCL1 /PROD=myeloid cell leukemia sequence 1 (BCL2-related) /DB_XREF=gi:11386164 /UG=Hs.86386 myeloid cell leukemia sequence 1 (BCL2-related) /FL=gb:NM_021960.1 gb:AF118124.1 NM_021960 myeloid cell leukemia sequence 1 (BCL2-related) MCL1 4170 NM_021960 /// NM_182763 0001709 // cell fate determination // non-traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008632 // apoptotic program // traceable author statement /// 0019725 // cellular homeostasis // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0015266 // protein channel activity // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200799_at NM_005345 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3 NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0006402 // mRNA catabolic process // traceable author statement /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 200800_s_at NM_005345 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005345.3 /DEF=Homo sapiens heat shock 70kD protein 1A (HSPA1A), mRNA. /FEA=mRNA /GEN=HSPA1A /PROD=heat shock 70kD protein 1A /DB_XREF=gi:5579469 /UG=Hs.8997 heat shock 70kD protein 1A /FL=gb:BC002453.1 gb:NM_005345.3 NM_005345 heat shock 70kDa protein 1A /// heat shock 70kDa protein 1B HSPA1A /// HSPA1B 3303 /// 3304 NM_005345 /// NM_005346 0006402 // mRNA catabolic process // traceable author statement /// 0006916 // anti-apoptosis // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 200801_x_at NM_001101 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001101.2 /DEF=Homo sapiens actin, beta (ACTB), mRNA. /FEA=mRNA /GEN=ACTB /PROD=beta actin /DB_XREF=gi:5016088 /UG=Hs.288061 actin, beta /FL=gb:BC001301.1 gb:BC002409.1 gb:BC004251.1 gb:NM_001101.2 NM_001101 actin, beta ACTB 60 NM_001101 0006928 // cell motion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from physical interaction 200802_at NM_006513 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006513.1 /DEF=Homo sapiens seryl-tRNA synthetase (SARS), mRNA. /FEA=mRNA /GEN=SARS /PROD=seryl-tRNA synthetase /DB_XREF=gi:5730028 /UG=Hs.4888 seryl-tRNA synthetase /FL=gb:BC000716.1 gb:NM_006513.1 gb:D49914.1 NM_006513 seryl-tRNA synthetase SARS 6301 NM_006513 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // traceable author statement /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200803_s_at AF033095 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF033095.1 /DEF=Homo sapiens testis enhanced gene transcript protein (TEGT) mRNA, complete cds. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript protein /DB_XREF=gi:2645728 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1 AF033095 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 0006915 // apoptosis // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation 0005626 // insoluble fraction // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200804_at NM_003217 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003217.1 /DEF=Homo sapiens testis enhanced gene transcript (TEGT), mRNA. /FEA=mRNA /GEN=TEGT /PROD=testis enhanced gene transcript /DB_XREF=gi:4507432 /UG=Hs.74637 testis enhanced gene transcript (BAX inhibitor 1) /FL=gb:BC000916.1 gb:AF033095.1 gb:NM_003217.1 NM_003217 transmembrane BAX inhibitor motif containing 6 TMBIM6 7009 NM_001098576 /// NM_003217 0006915 // apoptosis // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation 0005626 // insoluble fraction // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200805_at NM_006816 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006816.1 /DEF=Homo sapiens endoplasmic reticulum glycoprotein (GP36B), mRNA. /FEA=mRNA /GEN=GP36B /PROD=endoplasmic reticulum glycoprotein /DB_XREF=gi:5803022 /UG=Hs.75864 endoplasmic reticulum glycoprotein /FL=gb:U10362.1 gb:NM_006816.1 NM_006816 lectin, mannose-binding 2 LMAN2 10960 NM_006816 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005529 // sugar binding // inferred from electronic annotation 200806_s_at BE256479 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE256479 /FEA=EST /DB_XREF=gi:9126938 /DB_XREF=est:601111293F1 /CLONE=IMAGE:3352031 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1 BE256479 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // caspase activation // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044459 // plasma membrane part // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0043498 // cell surface binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200807_s_at NM_002156 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002156.1 /DEF=Homo sapiens heat shock 60kD protein 1 (chaperonin) (HSPD1), mRNA. /FEA=mRNA /GEN=HSPD1 /PROD=heat shock 60kD protein 1 (chaperonin) /DB_XREF=gi:4504520 /UG=Hs.79037 heat shock 60kD protein 1 (chaperonin) /FL=gb:BC002676.1 gb:BC003030.1 gb:M34664.1 gb:M22382.1 gb:NM_002156.1 NM_002156 heat shock 60kDa protein 1 (chaperonin) HSPD1 3329 NM_002156 /// NM_199440 0002368 // B cell cytokine production // inferred from direct assay /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // inferred from direct assay /// 0002842 // positive regulation of T cell mediated immune response to tumor cell // inferred from direct assay /// 0006458 // 'de novo' protein folding // inferred from sequence or structural similarity /// 0006919 // caspase activation // inferred from direct assay /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from direct assay /// 0032727 // positive regulation of interferon-alpha production // inferred from electronic annotation /// 0032727 // positive regulation of interferon-alpha production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from direct assay /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from direct assay /// 0032735 // positive regulation of interleukin-12 production // inferred from direct assay /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0042026 // protein refolding // inferred from direct assay /// 0042100 // B cell proliferation // inferred from direct assay /// 0042110 // T cell activation // inferred from electronic annotation /// 0042110 // T cell activation // inferred from direct assay /// 0042113 // B cell activation // inferred from direct assay /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0044267 // cellular protein metabolic process // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0048291 // isotype switching to IgG isotypes // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0050870 // positive regulation of T cell activation // inferred from direct assay /// 0050870 // positive regulation of T cell activation // inferred from sequence or structural similarity /// 0051131 // chaperone-mediated protein complex assembly // inferred from sequence or structural similarity /// 0051604 // protein maturation // inferred from sequence or structural similarity 0005615 // extracellular space // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement /// 0005769 // early endosome // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005905 // coated pit // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0019907 // cyclin-dependent protein kinase activating kinase holoenzyme complex // inferred from direct assay /// 0030135 // coated vesicle // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0030141 // secretory granule // inferred from sequence or structural similarity /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation /// 0044459 // plasma membrane part // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0001530 // lipopolysaccharide binding // inferred from direct assay /// 0002039 // p53 binding // inferred from physical interaction /// 0003688 // DNA replication origin binding // inferred from sequence or structural similarity /// 0003697 // single-stranded DNA binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from sequence or structural similarity /// 0043498 // cell surface binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred by curator /// 0051082 // unfolded protein binding // inferred from sequence or structural similarity /// 0051087 // chaperone binding // inferred from physical interaction 200808_s_at NM_003461 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003461.1 /DEF=Homo sapiens zyxin (ZYX), mRNA. /FEA=mRNA /GEN=ZYX /PROD=zyxin /DB_XREF=gi:4508046 /UG=Hs.75873 zyxin /FL=gb:NM_003461.1 NM_003461 zyxin ZYX 7791 NM_001010972 /// NM_003461 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200809_x_at NM_000976 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000976.1 /DEF=Homo sapiens ribosomal protein L12 (RPL12), mRNA. /FEA=mRNA /GEN=RPL12 /PROD=ribosomal protein L12 /DB_XREF=gi:4506596 /UG=Hs.182979 ribosomal protein L12 /FL=gb:L06505.1 gb:NM_000976.1 NM_000976 ribosomal protein L12 RPL12 6136 NM_000976 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200810_s_at NM_001280 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1 NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200811_at NM_001280 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001280.1 /DEF=Homo sapiens cold inducible RNA-binding protein (CIRBP), mRNA. /FEA=mRNA /GEN=CIRBP /PROD=cold inducible RNA-binding protein /DB_XREF=gi:4502846 /UG=Hs.119475 cold inducible RNA-binding protein /FL=gb:D78134.1 gb:BC000403.1 gb:BC000901.1 gb:AF021336.1 gb:NM_001280.1 NM_001280 cold inducible RNA binding protein CIRBP 1153 NM_001280 /// NR_023312 /// NR_023313 0006950 // response to stress // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009409 // response to cold // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200812_at NM_006429 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006429.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 7 (eta) (CCT7), mRNA. /FEA=mRNA /GEN=CCT7 /PROD=chaperonin containing TCP1, subunit 7 (eta) /DB_XREF=gi:5453606 /UG=Hs.108809 chaperonin containing TCP1, subunit 7 (eta) /FL=gb:AF026292.1 gb:NM_006429.1 NM_006429 chaperonin containing TCP1, subunit 7 (eta) CCT7 10574 NM_001009570 /// NM_006429 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200813_s_at BE256969 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE256969 /FEA=EST /DB_XREF=gi:9127437 /DB_XREF=est:601112157F1 /CLONE=IMAGE:3352623 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 BE256969 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa PAFAH1B1 5048 NM_000430 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001675 // acrosome formation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in the cerebral cortex // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200814_at NM_006263 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006263.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1), mRNA. /FEA=mRNA /GEN=PSME1 /PROD=proteasome (prosome, macropain) activatorsubunit 1 (PA28 alpha) /DB_XREF=gi:5453989 /UG=Hs.75348 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) /FL=gb:BC000352.1 gb:L07633.1 gb:NM_006263.1 NM_006263 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) PSME1 5720 NM_006263 /// NM_176783 0019884 // antigen processing and presentation of exogenous antigen // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008538 // proteasome activator activity // inferred from electronic annotation 200815_s_at L13386 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:L13386.1 /DEF=Homo sapiens (clone 47) Miller-Dieker lissencephaly protein (LIS1) mRNA, complete cds. /FEA=mRNA /GEN=LIS1 /PROD=Miller-Dieker lissencephaly protein /DB_XREF=gi:349825 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 L13386 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa PAFAH1B1 5048 NM_000430 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001675 // acrosome formation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in the cerebral cortex // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200816_s_at NM_000430 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000430.2 /DEF=Homo sapiens platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) (PAFAH1B1), mRNA. /FEA=mRNA /GEN=PAFAH1B1 /PROD=platelet-activating factor acetylhydrolase,isoform Ib, alpha subunit (45kD) /DB_XREF=gi:6031206 /UG=Hs.77318 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) /FL=gb:L13385.1 gb:L13386.1 gb:NM_000430.2 NM_000430 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa PAFAH1B1 5048 NM_000430 0000132 // establishment of mitotic spindle orientation // inferred from mutant phenotype /// 0000226 // microtubule cytoskeleton organization // inferred from sequence or structural similarity /// 0001675 // acrosome formation // inferred from sequence or structural similarity /// 0001764 // neuron migration // inferred from sequence or structural similarity /// 0006810 // transport // inferred from electronic annotation /// 0007017 // microtubule-based process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from sequence or structural similarity /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007405 // neuroblast proliferation // inferred from sequence or structural similarity /// 0007611 // learning or memory // inferred from sequence or structural similarity /// 0008090 // retrograde axon cargo transport // inferred from sequence or structural similarity /// 0008344 // adult locomotory behavior // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0019226 // transmission of nerve impulse // inferred from sequence or structural similarity /// 0021540 // corpus callosum morphogenesis // inferred from mutant phenotype /// 0021766 // hippocampus development // inferred from sequence or structural similarity /// 0021819 // layer formation in the cerebral cortex // inferred from sequence or structural similarity /// 0021987 // cerebral cortex development // inferred from mutant phenotype /// 0030036 // actin cytoskeleton organization // inferred from sequence or structural similarity /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from sequence or structural similarity /// 0046469 // platelet activating factor metabolic process // inferred from sequence or structural similarity /// 0047496 // vesicle transport along microtubule // inferred from sequence or structural similarity /// 0048854 // brain morphogenesis // inferred from mutant phenotype /// 0050885 // neuromuscular process controlling balance // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation 0000235 // astral microtubule // inferred from direct assay /// 0000776 // kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005813 // centrosome // inferred from sequence or structural similarity /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031252 // cell leading edge // inferred from sequence or structural similarity /// 0031512 // motile primary cilium // inferred from sequence or structural similarity /// 0031513 // nonmotile primary cilium // inferred from sequence or structural similarity /// 0031965 // nuclear membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from sequence or structural similarity /// 0008201 // heparin binding // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0034452 // dynactin binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0043274 // phospholipase binding // inferred from sequence or structural similarity /// 0045502 // dynein binding // inferred from direct assay /// 0051219 // phosphoprotein binding // inferred from sequence or structural similarity 200817_x_at NM_001014 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001014.1 /DEF=Homo sapiens ribosomal protein S10 (RPS10), mRNA. /FEA=mRNA /GEN=RPS10 /PROD=ribosomal protein S10 /DB_XREF=gi:4506678 /UG=Hs.76230 ribosomal protein S10 /FL=gb:BC001032.1 gb:BC001955.1 gb:BC005012.1 gb:NM_001014.1 gb:U14972.1 NM_001014 ribosomal protein S10 RPS10 6204 NM_001014 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200818_at NM_001697 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001697.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) (ATP5O), mRNA. /FEA=mRNA /GEN=ATP5O /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, O subunit (oligomycin sensitivity conferringprotein) /DB_XREF=gi:4502302 /UG=Hs.76572 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) /FL=gb:NM_001697.1 NM_001697 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit ATP5O 539 NM_001697 0006200 // ATP catabolic process // inferred from direct assay /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0042776 // mitochondrial ATP synthesis coupled proton transport // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0008144 // drug binding // inferred from direct assay /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 200819_s_at NM_001018 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001018.1 /DEF=Homo sapiens ribosomal protein S15 (RPS15), mRNA. /FEA=mRNA /GEN=RPS15 /PROD=ribosomal protein S15 /DB_XREF=gi:4506686 /UG=Hs.133230 ribosomal protein S15 /FL=gb:J02984.1 gb:NM_001018.1 NM_001018 ribosomal protein S15 RPS15 6209 NM_001018 0000056 // ribosomal small subunit export from nucleus // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // non-traceable author statement /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003677 // DNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200820_at NM_002812 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002812.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (PSMD8), mRNA. /FEA=mRNA /GEN=PSMD8 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 8 /DB_XREF=gi:4506232 /UG=Hs.78466 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 /FL=gb:D38047.1 gb:BC001164.1 gb:NM_002812.1 NM_002812 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 PSMD8 5714 NM_002812 0006508 // proteolysis // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031177 // phosphopantetheine binding // inferred from electronic annotation 200821_at NM_013995 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013995.1 /DEF=Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant LAMP2B, mRNA. /FEA=mRNA /GEN=LAMP2 /PROD=lysosomal-associated membrane protein 2precursor /DB_XREF=gi:7669502 /UG=Hs.8262 lysosomal-associated membrane protein 2 /FL=gb:U36336.1 gb:BC002965.1 gb:NM_013995.1 NM_013995 lysosomal-associated membrane protein 2 LAMP2 3920 NM_001122606 /// NM_002294 /// NM_013995 0005977 // glycogen metabolic process // inferred from electronic annotation 0005624 // membrane fraction // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031088 // platelet dense granule membrane // not recorded /// 0031088 // platelet dense granule membrane // inferred from direct assay 200822_x_at NM_000365 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000365.1 /DEF=Homo sapiens triosephosphate isomerase 1 (TPI1), mRNA. /FEA=mRNA /GEN=TPI1 /PROD=triosephosphate isomerase 1 /DB_XREF=gi:4507644 /UG=Hs.83848 triosephosphate isomerase 1 /FL=gb:BC004230.1 gb:NM_000365.1 NM_000365 triosephosphate isomerase 1 TPI1 7167 NM_000365 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006094 // gluconeogenesis // inferred from electronic annotation /// 0006096 // glycolysis // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009790 // embryonic development // inferred from electronic annotation /// 0019682 // glyceraldehyde-3-phosphate metabolic process // inferred from electronic annotation 0005829 // cytosol // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004807 // triose-phosphate isomerase activity // not recorded /// 0004807 // triose-phosphate isomerase activity // non-traceable author statement /// 0004807 // triose-phosphate isomerase activity // traceable author statement /// 0004807 // triose-phosphate isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 200823_x_at NM_000992 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000992.1 /DEF=Homo sapiens ribosomal protein L29 (RPL29), mRNA. /FEA=mRNA /GEN=RPL29 /PROD=ribosomal protein L29 /DB_XREF=gi:4506628 /UG=Hs.183698 ribosomal protein L29 /FL=gb:U49083.1 gb:NM_000992.1 gb:U10248.1 NM_000992 similar to ribosomal protein L29 /// ribosomal protein L29 /// ribosomal protein L29 pseudogene 4 LOC100131713 /// RPL29 /// RPL29P4 100131713 /// 387101 /// 6159 NM_000992 /// XM_001723470 /// XM_001723471 /// XM_001724270 /// XM_001724272 /// XM_001725513 /// XM_001725514 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007566 // embryo implantation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation 200824_at NM_000852 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000852.2 /DEF=Homo sapiens glutathione S-transferase pi (GSTP1), mRNA. /FEA=mRNA /GEN=GSTP1 /PROD=glutathione transferase /DB_XREF=gi:6552334 /UG=Hs.226795 glutathione S-transferase pi /FL=gb:U62589.1 gb:U30897.1 gb:NM_000852.2 NM_000852 glutathione S-transferase pi 1 GSTP1 2950 NM_000852 0006916 // anti-apoptosis // traceable author statement /// 0007417 // central nervous system development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement 0004364 // glutathione transferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation 200825_s_at NM_006389 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006389.2 /DEF=Homo sapiens oxygen regulated protein (150kD) (ORP150), mRNA. /FEA=mRNA /GEN=ORP150 /PROD=oxygen regulated protein precursor /DB_XREF=gi:13699861 /UG=Hs.277704 oxygen regulated protein (150kD) /FL=gb:NM_006389.2 gb:U65785.1 NM_006389 hypoxia up-regulated 1 HYOU1 10525 NM_001130991 /// NM_006389 0001666 // response to hypoxia // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 200826_at NM_004597 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004597.3 /DEF=Homo sapiens small nuclear ribonucleoprotein D2 polypeptide (16.5kD) (SNRPD2), mRNA. /FEA=mRNA /GEN=SNRPD2 /PROD=small nuclear ribonucleoprotein D2 polypeptide(16.5kD) /DB_XREF=gi:7242206 /UG=Hs.53125 small nuclear ribonucleoprotein D2 polypeptide (16.5kD) /FL=gb:BC000486.1 gb:BC001930.1 gb:U15008.1 gb:NM_004597.3 NM_004597 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa SNRPD2 6633 NM_004597 /// NM_177542 0000245 // spliceosome assembly // traceable author statement /// 0000387 // spliceosomal snRNP biogenesis // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005681 // spliceosome // traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200827_at NM_000302 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000302.1 /DEF=Homo sapiens procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) (PLOD), mRNA. /FEA=mRNA /GEN=PLOD /PROD=procollagen-lysine 5-dioxygenase /DB_XREF=gi:4557836 /UG=Hs.75093 procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI) /FL=gb:L06419.1 gb:NM_000302.1 NM_000302 procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 PLOD1 5351 NM_000302 /// XM_001715762 /// XM_001720424 /// XM_001721275 0001666 // response to hypoxia // inferred from expression pattern /// 0006464 // protein modification process // non-traceable author statement /// 0008544 // epidermis development // inferred from mutant phenotype /// 0008544 // epidermis development // traceable author statement /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0046947 // hydroxylysine biosynthetic process // traceable author statement /// 0055114 // oxidation reduction // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0008475 // procollagen-lysine 5-dioxygenase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0016706 // oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors // inferred from electronic annotation /// 0031418 // L-ascorbic acid binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200828_s_at BE871379 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE871379 /FEA=EST /DB_XREF=gi:10320155 /DB_XREF=est:601449306F1 /CLONE=IMAGE:3853200 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1 BE871379 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200829_x_at NM_003457 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003457.1 /DEF=Homo sapiens zinc finger protein 207 (ZNF207), mRNA. /FEA=mRNA /GEN=ZNF207 /PROD=zinc finger protein 207 /DB_XREF=gi:4508016 /UG=Hs.62112 zinc finger protein 207 /FL=gb:AF046001.1 gb:NM_003457.1 NM_003457 zinc finger protein 207 ZNF207 7756 NM_001032293 /// NM_001098507 /// NM_003457 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200830_at NM_002808 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002808.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2), mRNA. /FEA=mRNA /GEN=PSMD2 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 2 /DB_XREF=gi:4506226 /UG=Hs.74619 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 /FL=gb:D78151.1 gb:BC002368.1 gb:BC002997.1 gb:NM_002808.1 gb:U18247.1 gb:U12596.1 NM_002808 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 PSMD2 5708 NM_002808 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0000502 // proteasome complex // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 200831_s_at AA678241 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA678241 /FEA=EST /DB_XREF=gi:2658763 /DB_XREF=est:zi27a06.s1 /CLONE=IMAGE:431986 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1 AA678241 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // traceable author statement /// 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 200832_s_at AB032261 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB032261.1 /DEF=Homo sapiens Scd mRNA for stearoyl-CoA desaturase, complete cds. /FEA=mRNA /GEN=Scd /PROD=stearoyl-CoA desaturase /DB_XREF=gi:7415720 /UG=Hs.119597 stearoyl-CoA desaturase (delta-9-desaturase) /FL=gb:AF097514.1 gb:NM_005063.1 gb:AB032261.1 AB032261 stearoyl-CoA desaturase (delta-9-desaturase) SCD 6319 NM_005063 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004768 // stearoyl-CoA 9-desaturase activity // traceable author statement /// 0004768 // stearoyl-CoA 9-desaturase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 200833_s_at NM_015646 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015646.1 /DEF=Homo sapiens RAP1B, member of RAS oncogene family (RAP1B), mRNA. /FEA=mRNA /GEN=RAP1B /PROD=DKFZP586H0723 protein /DB_XREF=gi:7661677 /UG=Hs.156764 RAP1B, member of RAS oncogene family /FL=gb:BC000176.2 gb:NM_015646.1 NM_015646 hCG1757335 /// RAP1B, member of RAS oncogene family hCG_1757335 /// RAP1B 5908 /// 643752 NM_001010942 /// NM_001089704 /// NM_015646 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 200834_s_at NM_001024 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001024.1 /DEF=Homo sapiens ribosomal protein S21 (RPS21), mRNA. /FEA=mRNA /GEN=RPS21 /PROD=ribosomal protein S21 /DB_XREF=gi:4506698 /UG=Hs.1948 ribosomal protein S21 /FL=gb:L04483.1 gb:NM_001024.1 NM_001024 ribosomal protein S21 RPS21 6227 NM_001024 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0030154 // cell differentiation // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0047485 // protein N-terminus binding // inferred from physical interaction 200835_s_at AI553791 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI553791 /FEA=EST /DB_XREF=gi:4486154 /DB_XREF=est:tn29a04.x1 /CLONE=IMAGE:2169006 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1 AI553791 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200836_s_at NM_002375 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002375.1 /DEF=Homo sapiens microtubule-associated protein 4 (MAP4), mRNA. /FEA=mRNA /GEN=MAP4 /PROD=microtubule-associated protein 4 /DB_XREF=gi:4505098 /UG=Hs.239298 microtubule-associated protein 4 /FL=gb:M64571.1 gb:NM_002375.1 gb:U19727.1 NM_002375 microtubule-associated protein 4 MAP4 4134 NM_001134364 /// NM_001134365 /// NM_002375 /// NM_030884 /// NM_030885 0007026 // negative regulation of microtubule depolymerization // inferred from electronic annotation 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200837_at NM_005745 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005745.3 /DEF=Homo sapiens accessory proteins BAP31BAP29 (DXS1357E), mRNA. /FEA=mRNA /GEN=DXS1357E /PROD=accessory proteins BAP31BAP29 /DB_XREF=gi:10047078 /UG=Hs.291904 accessory proteins BAP31BAP29 /FL=gb:NM_005745.3 NM_005745 B-cell receptor-associated protein 31 BCAP31 10134 NM_001139441 /// NM_001139457 /// NM_005745 /// NR_024450 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0006955 // immune response // non-traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200838_at NM_001908 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1 NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0042981 // regulation of apoptosis // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // traceable author statement /// 0005625 // soluble fraction // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030984 // kininogen binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 200839_s_at NM_001908 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001908.1 /DEF=Homo sapiens cathepsin B (CTSB), mRNA. /FEA=mRNA /GEN=CTSB /PROD=cathepsin B /DB_XREF=gi:4503138 /UG=Hs.297939 cathepsin B /FL=gb:M14221.1 gb:L16510.1 gb:NM_001908.1 NM_001908 cathepsin B CTSB 1508 NM_001908 /// NM_147780 /// NM_147781 /// NM_147782 /// NM_147783 0006508 // proteolysis // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0042981 // regulation of apoptosis // traceable author statement /// 0050790 // regulation of catalytic activity // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005622 // intracellular // traceable author statement /// 0005625 // soluble fraction // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from direct assay /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030984 // kininogen binding // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 200840_at NM_005548 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005548.1 /DEF=Homo sapiens lysyl-tRNA synthetase (KARS), mRNA. /FEA=mRNA /GEN=KARS /PROD=lysyl-tRNA synthetase /DB_XREF=gi:5031814 /UG=Hs.3100 lysyl-tRNA synthetase /FL=gb:BC004132.1 gb:D32053.1 gb:NM_005548.1 NM_005548 lysyl-tRNA synthetase KARS 3735 NM_001130089 /// NM_005548 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0006430 // lysyl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // non-traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay 0000049 // tRNA binding // non-traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // inferred from direct assay /// 0004824 // lysine-tRNA ligase activity // inferred from electronic annotation /// 0004824 // lysine-tRNA ligase activity // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200841_s_at AI142677 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI142677 /FEA=EST /DB_XREF=gi:3659036 /DB_XREF=est:ok33h03.s1 /CLONE=IMAGE:1509653 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI142677 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // inferred from electronic annotation /// 0004827 // proline-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200842_s_at AI475965 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI475965 /FEA=EST /DB_XREF=gi:4329010 /DB_XREF=est:tl96a09.x1 /CLONE=IMAGE:2154904 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 AI475965 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // inferred from electronic annotation /// 0004827 // proline-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200843_s_at NM_004446 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004446.1 /DEF=Homo sapiens glutamyl-prolyl-tRNA synthetase (EPRS), mRNA. /FEA=mRNA /GEN=EPRS /PROD=glutamyl-prolyl tRNA synthetase /DB_XREF=gi:4758293 /UG=Hs.55921 glutamyl-prolyl-tRNA synthetase /FL=gb:NM_004446.1 NM_004446 glutamyl-prolyl-tRNA synthetase EPRS 2058 NM_004446 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006424 // glutamyl-tRNA aminoacylation // inferred from electronic annotation /// 0006433 // prolyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004818 // glutamate-tRNA ligase activity // inferred from electronic annotation /// 0004827 // proline-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200844_s_at BE869583 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE869583 /FEA=EST /DB_XREF=gi:10318463 /DB_XREF=est:601445695F1 /CLONE=IMAGE:3849815 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1 BE869583 peroxiredoxin 6 PRDX6 9588 NM_004905 0006979 // response to oxidative stress // inferred from direct assay /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200845_s_at NM_004905 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004905.1 /DEF=Homo sapiens anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) (KIAA0106), mRNA. /FEA=mRNA /GEN=KIAA0106 /PROD=anti-oxidant protein 2 (non-selenium glutathioneperoxidase, acidic calcium-independent phospholipase A2) /DB_XREF=gi:4758637 /UG=Hs.120 anti-oxidant protein 2 (non-selenium glutathione peroxidase, acidic calcium-independent phospholipase A2) /FL=gb:D14662.1 gb:NM_004905.1 NM_004905 peroxiredoxin 6 PRDX6 9588 NM_004905 0006979 // response to oxidative stress // inferred from direct assay /// 0009395 // phospholipid catabolic process // inferred from direct assay /// 0016042 // lipid catabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0004623 // phospholipase A2 activity // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 200846_s_at NM_002708 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002708.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, alpha isoform (PPP1CA), mRNA. /FEA=mRNA /GEN=PPP1CA /PROD=protein phosphatase 1, catalytic subunit, alphaisoform /DB_XREF=gi:4506002 /UG=Hs.183994 protein phosphatase 1, catalytic subunit, alpha isoform /FL=gb:BC001888.1 gb:BC004482.1 gb:M63960.1 gb:NM_002708.1 NM_002708 protein phosphatase 1, catalytic subunit, alpha isoform PPP1CA 5499 NM_001008709 /// NM_002708 /// NM_206873 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0048754 // branching morphogenesis of a tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005654 // nucleoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // cell soma // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0043021 // ribonucleoprotein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200847_s_at NM_016127 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016127.1 /DEF=Homo sapiens HSPC035 protein (LOC51669), mRNA. /FEA=mRNA /GEN=LOC51669 /PROD=HSPC035 protein /DB_XREF=gi:7706384 /UG=Hs.279921 HSPC035 protein /FL=gb:AF100748.1 gb:AF078855.1 gb:NM_016127.1 NM_016127 transmembrane protein 66 TMEM66 51669 NM_016127 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200848_at AA479488 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA479488 /FEA=EST /DB_XREF=gi:2208044 /DB_XREF=est:zv21c09.s1 /CLONE=IMAGE:754288 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AA479488 S-adenosylhomocysteine hydrolase-like 1 AHCYL1 10768 NM_006621 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200849_s_at AI589266 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI589266 /FEA=EST /DB_XREF=gi:4598314 /DB_XREF=est:tr58c06.x2 /CLONE=IMAGE:2222506 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 AI589266 S-adenosylhomocysteine hydrolase-like 1 AHCYL1 10768 NM_006621 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200850_s_at NM_006621 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006621.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase-like 1 (AHCYL1), mRNA. /FEA=mRNA /GEN=AHCYL1 /PROD=S-adenosylhomocysteine hydrolase-like 1 /DB_XREF=gi:5729723 /UG=Hs.4113 S-adenosylhomocysteine hydrolase-like 1 /FL=gb:U82761.1 gb:NM_006621.1 NM_006621 S-adenosylhomocysteine hydrolase-like 1 AHCYL1 10768 NM_006621 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200851_s_at NM_014761 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014761.1 /DEF=Homo sapiens KIAA0174 gene product (KIAA0174), mRNA. /FEA=mRNA /GEN=KIAA0174 /PROD=KIAA0174 gene product /DB_XREF=gi:7661971 /UG=Hs.75824 KIAA0174 gene product /FL=gb:D79996.1 gb:BC000430.1 gb:BC004359.1 gb:NM_014761.1 NM_014761 KIAA0174 KIAA0174 9798 NM_014761 0005793 // ER-Golgi intermediate compartment // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200852_x_at NM_005273 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005273.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2 (GNB2), mRNA. /FEA=mRNA /GEN=GNB2 /PROD=guanine nucleotide binding protein (G protein),beta polypeptide 2 /DB_XREF=gi:4885282 /UG=Hs.91299 guanine nucleotide binding protein (G protein), beta polypeptide 2 /FL=gb:M16538.1 gb:M36429.1 gb:NM_005273.1 NM_005273 guanine nucleotide binding protein (G protein), beta polypeptide 2 GNB2 2783 NM_005273 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0009755 // hormone-mediated signaling // not recorded 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005246 // calcium channel regulator activity // inferred from electronic annotation 200853_at NM_002106 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002106.1 /DEF=Homo sapiens H2A histone family, member Z (H2AFZ), mRNA. /FEA=mRNA /GEN=H2AFZ /PROD=H2A histone family, member Z /DB_XREF=gi:4504254 /UG=Hs.119192 H2A histone family, member Z /FL=gb:M37583.1 gb:NM_002106.1 NM_002106 H2A histone family, member Z H2AFZ 3015 NM_002106 0006334 // nucleosome assembly // inferred from electronic annotation 0000786 // nucleosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 200854_at AB028970 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB028970.1 /DEF=Homo sapiens mRNA for KIAA1047 protein, partial cds. /FEA=mRNA /GEN=KIAA1047 /PROD=KIAA1047 protein /DB_XREF=gi:5689430 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 AB028970 nuclear receptor co-repressor 1 NCOR1 9611 NM_006311 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200855_at AW771910 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW771910 /FEA=EST /DB_XREF=gi:7703971 /DB_XREF=est:hn66c11.x1 /CLONE=IMAGE:3032852 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 AW771910 chromosome 20 open reading frame 191 /// similar to nuclear receptor co-repressor 1 /// nuclear receptor co-repressor 1 C20orf191 /// LOC100133918 /// NCOR1 100133918 /// 149934 /// 9611 NM_006311 /// NR_003678 /// XM_001725872 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200856_x_at BF437948 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF437948 /FEA=EST /DB_XREF=gi:11450465 /DB_XREF=est:7q63b10.x1 /CLONE=IMAGE:3702882 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 BF437948 chromosome 20 open reading frame 191 /// similar to nuclear receptor co-repressor 1 /// nuclear receptor co-repressor 1 C20orf191 /// LOC100133918 /// NCOR1 100133918 /// 149934 /// 9611 NM_006311 /// NR_003678 /// XM_001725872 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200857_s_at NM_006311 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006311.1 /DEF=Homo sapiens nuclear receptor co-repressor 1 (NCOR1), mRNA. /FEA=mRNA /GEN=NCOR1 /PROD=nuclear receptor co-repressor 1 /DB_XREF=gi:5454137 /UG=Hs.144904 nuclear receptor co-repressor 1 /FL=gb:AF044209.1 gb:NM_006311.1 NM_006311 nuclear receptor co-repressor 1 NCOR1 9611 NM_006311 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 200858_s_at NM_001012 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001012.1 /DEF=Homo sapiens ribosomal protein S8 (RPS8), mRNA. /FEA=mRNA /GEN=RPS8 /PROD=ribosomal protein S8 /DB_XREF=gi:4506742 /UG=Hs.151604 ribosomal protein S8 /FL=gb:NM_001012.1 NM_001012 ribosomal protein S8 RPS8 6202 NM_001012 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200859_x_at NM_001456 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001456.1 /DEF=Homo sapiens filamin A, alpha (actin-binding protein-280) (FLNA), mRNA. /FEA=mRNA /GEN=FLNA /PROD=filamin 1 (actin-binding protein-280) /DB_XREF=gi:4503744 /UG=Hs.195464 filamin A, alpha (actin-binding protein-280) /FL=gb:NM_001456.1 NM_001456 filamin A, alpha (actin binding protein 280) FLNA 2316 NM_001110556 /// NM_001456 0007195 // dopamine receptor, adenylate cyclase inhibiting pathway // inferred from mutant phenotype /// 0031532 // actin cytoskeleton reorganization // inferred from direct assay /// 0034394 // protein localization at cell surface // inferred from direct assay /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from mutant phenotype /// 0043113 // receptor clustering // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043433 // negative regulation of transcription factor activity // inferred from direct assay /// 0045022 // early endosome to late endosome transport // inferred from electronic annotation /// 0045184 // establishment of protein localization // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0051220 // cytoplasmic sequestering of protein // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred by curator 0001948 // glycoprotein binding // inferred from direct assay /// 0001948 // glycoprotein binding // inferred from physical interaction /// 0003779 // actin binding // inferred from electronic annotation /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005080 // protein kinase C binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0017048 // Rho GTPase binding // inferred from direct assay /// 0031267 // small GTPase binding // inferred from direct assay /// 0034988 // Fc-gamma receptor I complex binding // inferred from direct assay /// 0034989 // GTP-Ral binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0048365 // Rac GTPase binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from direct assay /// 0051015 // actin filament binding // inferred from physical interaction 200860_s_at BC000779 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000779.1 /DEF=Homo sapiens, Similar to KIAA1007 protein, clone MGC:692, mRNA, complete cds. /FEA=mRNA /PROD=Similar to KIAA1007 protein /DB_XREF=gi:12653966 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1 BC000779 CCR4-NOT transcription complex, subunit 1 CNOT1 23019 NM_016284 /// NM_206999 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005529 // sugar binding // inferred from electronic annotation 200861_at NM_016284 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016284.1 /DEF=Homo sapiens KIAA1007 protein (KIAA1007), mRNA. /FEA=mRNA /GEN=KIAA1007 /PROD=KIAA1007 protein /DB_XREF=gi:7706213 /UG=Hs.279949 KIAA1007 protein /FL=gb:BC000779.1 gb:AF110778.1 gb:NM_016284.1 NM_016284 CCR4-NOT transcription complex, subunit 1 CNOT1 23019 NM_016284 /// NM_206999 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005529 // sugar binding // inferred from electronic annotation 200862_at NM_014762 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014762.1 /DEF=Homo sapiens seladin-1 (KIAA0018), mRNA. /FEA=mRNA /GEN=KIAA0018 /PROD=seladin-1 /DB_XREF=gi:13375617 /UG=Hs.75616 seladin-1 /FL=gb:AF261758.1 gb:BC004375.1 gb:NM_014762.1 NM_014762 24-dehydrocholesterol reductase DHCR24 1718 NM_014762 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from sequence or structural similarity /// 0006695 // cholesterol biosynthetic process // non-traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006915 // apoptosis // non-traceable author statement /// 0006916 // anti-apoptosis // inferred from direct assay /// 0006979 // response to oxidative stress // inferred from expression pattern /// 0007050 // cell cycle arrest // non-traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009888 // tissue development // inferred from mutant phenotype /// 0016044 // membrane organization // inferred from electronic annotation /// 0016125 // sterol metabolic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030539 // male genitalia development // inferred from electronic annotation /// 0031639 // plasminogen activation // inferred from electronic annotation /// 0042987 // amyloid precursor protein catabolic process // inferred from electronic annotation /// 0043154 // negative regulation of caspase activity // inferred from direct assay /// 0043526 // neuroprotection // non-traceable author statement /// 0043588 // skin development // inferred from sequence or structural similarity /// 0043588 // skin development // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016628 // oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0042605 // peptide antigen binding // inferred from physical interaction /// 0050614 // delta24-sterol reductase activity // not recorded /// 0050660 // FAD binding // inferred from electronic annotation 200863_s_at AI215102 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI215102 /FEA=EST /DB_XREF=gi:3778703 /DB_XREF=est:qg69g05.x1 /CLONE=IMAGE:1840472 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1 AI215102 RAB11A, member RAS oncogene family RAB11A 8766 NM_004663 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200864_s_at NM_004663 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004663.1 /DEF=Homo sapiens RAB11A, member RAS oncogene family (RAB11A), mRNA. /FEA=mRNA /GEN=RAB11A /PROD=RAB11A, member RAS oncogene family /DB_XREF=gi:4758983 /UG=Hs.75618 RAB11A, member RAS oncogene family /FL=gb:AF000231.1 gb:NM_004663.1 NM_004663 RAB11A, member RAS oncogene family RAB11A 8766 NM_004663 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0048227 // plasma membrane to endosome transport // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0019905 // syntaxin binding // non-traceable author statement 200865_at AI001896 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI001896 /FEA=EST /DB_XREF=gi:3202367 /DB_XREF=est:ot42a05.s1 /CLONE=IMAGE:1619408 /UG=Hs.7811 eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) /FL=gb:BC000490.1 gb:U94855.1 gb:NM_003754.1 AI001896 eukaryotic translation initiation factor 3, subunit F EIF3F 8665 NM_003754 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200866_s_at M32221 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M32221.1 /DEF=Human saposin proteins A-D mRNA, complete cds. /FEA=mRNA /GEN=PSAP /DB_XREF=gi:337761 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1 M32221 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral to membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200867_at AL031685 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL031685 /DEF=Human DNA sequence from clone RP5-963K23 on chromosome 20q13.11-13.2 Contains a KRT18 (Keratin type I, Cytoskeletal 18 (Cytokeratin 18, CK18,CYK18)) pseudogene, a gene for a novel protein, the gene for spermatogenesis associated protein PD1 (KIAA0... /FEA=mRNA_2 /DB_XREF=gi:9368423 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1 AL031685 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200868_s_at NM_018683 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018683.1 /DEF=Homo sapiens zinc finger protein 313 (ZNF313), mRNA. /FEA=mRNA /GEN=ZNF313 /PROD=zinc finger protein 313 /DB_XREF=gi:8923897 /UG=Hs.10590 zinc finger protein 313 /FL=gb:AF265215.1 gb:NM_018683.1 NM_018683 ring finger protein 114 RNF114 55905 NM_018683 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200869_at NM_000980 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000980.1 /DEF=Homo sapiens ribosomal protein L18a (RPL18A), mRNA. /FEA=mRNA /GEN=RPL18A /PROD=ribosomal protein L18a /DB_XREF=gi:11415025 /UG=Hs.163593 ribosomal protein L18a /FL=gb:NM_000980.1 gb:L05093.1 NM_000980 ribosomal protein L18a pseudogene /// ribosomal protein L18a LOC390354 /// RPL18A 390354 /// 6142 NM_000980 /// NR_001593 /// XR_042140 /// XR_042141 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200870_at NM_007178 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007178.1 /DEF=Homo sapiens unr-interacting protein (UNRIP), mRNA. /FEA=mRNA /GEN=UNRIP /PROD=unr-interacting protein /DB_XREF=gi:6005931 /UG=Hs.3727 unr-interacting protein /FL=gb:BC000162.1 gb:AB024327.1 gb:NM_007178.1 gb:AL136691.1 gb:AF161496.1 NM_007178 serine/threonine kinase receptor associated protein STRAP 11171 NM_007178 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 200871_s_at NM_002778 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002778.1 /DEF=Homo sapiens prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) (PSAP), mRNA. /FEA=mRNA /GEN=PSAP /PROD=prosaposin (variant Gaucher disease and variantmetachromatic leukodystrophy) /DB_XREF=gi:11386146 /UG=Hs.78575 prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) /FL=gb:NM_002778.1 gb:BC004275.1 gb:J03077.1 gb:D00422.1 gb:M60255.1 gb:M32221.1 gb:M60257.1 gb:M60258.1 gb:M81355.1 NM_002778 prosaposin PSAP 5660 NM_001042465 /// NM_001042466 /// NM_002778 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006665 // sphingolipid metabolic process // inferred from electronic annotation /// 0006687 // glycosphingolipid metabolic process // traceable author statement /// 0006869 // lipid transport // traceable author statement /// 0007040 // lysosome organization // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016021 // integral to membrane // traceable author statement /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0008047 // enzyme activator activity // traceable author statement /// 0008289 // lipid binding // traceable author statement 200872_at NM_002966 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002966.1 /DEF=Homo sapiens S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) (S100A10), mRNA. /FEA=mRNA /GEN=S100A10 /PROD=S100 calcium-binding protein A10 /DB_XREF=gi:4506760 /UG=Hs.119301 S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)) /FL=gb:M81457.1 gb:M38591.1 gb:NM_002966.1 NM_002966 S100 calcium binding protein A10 S100A10 6281 NM_002966 0007165 // signal transduction // non-traceable author statement 0005739 // mitochondrion // inferred from direct assay 0005102 // receptor binding // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation 200873_s_at NM_006585 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006585.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 8 (theta) (CCT8), mRNA. /FEA=mRNA /GEN=CCT8 /PROD=chaperonin containing TCP1, subunit 8 (theta) /DB_XREF=gi:6005726 /UG=Hs.15071 chaperonin containing TCP1, subunit 8 (theta) /FL=gb:D13627.1 gb:NM_006585.1 NM_006585 chaperonin containing TCP1, subunit 8 (theta) CCT8 10694 NM_006585 0006457 // protein folding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0042623 // ATPase activity, coupled // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200874_s_at BE796327 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE796327 /FEA=EST /DB_XREF=gi:10217525 /DB_XREF=est:601591928F1 /CLONE=IMAGE:3946015 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1 BE796327 NOP56 ribonucleoprotein homolog (yeast) NOP56 10528 NM_006392 0006364 // rRNA processing // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement 0003723 // RNA binding // traceable author statement 200875_s_at NM_006392 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006392.1 /DEF=Homo sapiens nucleolar protein (KKED repeat) (NOP56), mRNA. /FEA=mRNA /GEN=NOP56 /PROD=nucleolar protein (KKED repeat) /DB_XREF=gi:5453793 /UG=Hs.296585 nucleolar protein (KKED repeat) /FL=gb:NM_006392.1 NM_006392 NOP56 ribonucleoprotein homolog (yeast) NOP56 10528 NM_006392 0006364 // rRNA processing // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement 0003723 // RNA binding // traceable author statement 200876_s_at NM_002793 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002793.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 1 (PSMB1), mRNA. /FEA=mRNA /GEN=PSMB1 /PROD=proteasome (prosome, macropain) subunit, betatype, 1 /DB_XREF=gi:4506192 /UG=Hs.75748 proteasome (prosome, macropain) subunit, beta type, 1 /FL=gb:BC000508.1 gb:NM_002793.1 NM_002793 proteasome (prosome, macropain) subunit, beta type, 1 PSMB1 5689 NM_002793 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200877_at NM_006430 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006430.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 4 (delta) (CCT4), mRNA. /FEA=mRNA /GEN=CCT4 /PROD=chaperonin containing TCP1, subunit 4 (delta) /DB_XREF=gi:5453604 /UG=Hs.79150 chaperonin containing TCP1, subunit 4 (delta) /FL=gb:U38846.1 gb:AF026291.1 gb:NM_006430.1 NM_006430 chaperonin containing TCP1, subunit 4 (delta) CCT4 10575 NM_006430 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 200878_at AF052094 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF052094.1 /DEF=Homo sapiens clone 23698 mRNA sequence. /FEA=mRNA /DB_XREF=gi:3360400 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1 AF052094 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II transcription factor activity, enhancer binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200879_s_at NM_001430 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001430.1 /DEF=Homo sapiens endothelial PAS domain protein 1 (EPAS1), mRNA. /FEA=mRNA /GEN=EPAS1 /PROD=endothelial PAS domain protein 1 /DB_XREF=gi:4503576 /UG=Hs.8136 endothelial PAS domain protein 1 /FL=gb:U51626.1 gb:U81984.1 gb:NM_001430.1 NM_001430 endothelial PAS domain protein 1 EPAS1 2034 NM_001430 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from genetic interaction /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003705 // RNA polymerase II transcription factor activity, enhancer binding // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction 200880_at AL534104 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL534104 /FEA=EST /DB_XREF=gi:12797597 /DB_XREF=est:AL534104 /CLONE=CS0DF005YF01 (3 prime) /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1 AL534104 HDJ2 protein DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200881_s_at NM_001539 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001539.1 /DEF=Homo sapiens heat shock protein, DNAJ-like 2 (HSJ2), mRNA. /FEA=mRNA /GEN=HSJ2 /PROD=heat shock protein, DNAJ-like 2 /DB_XREF=gi:4504510 /UG=Hs.94 DnaJ (Hsp40) homolog, subfamily A, member 1 /FL=gb:D13388.1 gb:L08069.1 gb:NM_001539.1 NM_001539 DnaJ (Hsp40) homolog, subfamily A, member 1 DNAJA1 3301 NM_001539 0006457 // protein folding // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006986 // response to unfolded protein // traceable author statement /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation 200882_s_at NM_002810 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002810.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 (PSMD4), mRNA. /FEA=mRNA /GEN=PSMD4 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 4 /DB_XREF=gi:5292160 /UG=Hs.148495 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 /FL=gb:BC002365.1 gb:U24704.1 gb:NM_002810.1 NM_002810 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 PSMD4 5710 NM_002810 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200883_at NM_003366 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003366.1 /DEF=Homo sapiens ubiquinol-cytochrome c reductase core protein II (UQCRC2), mRNA. /FEA=mRNA /GEN=UQCRC2 /PROD=ubiquinol-cytochrome c reductase core proteinII /DB_XREF=gi:4507842 /UG=Hs.173554 ubiquinol-cytochrome c reductase core protein II /FL=gb:BC000484.1 gb:BC003136.1 gb:J04973.1 gb:NM_003366.1 NM_003366 ubiquinol-cytochrome c reductase core protein II UQCRC2 7385 NM_003366 0006119 // oxidative phosphorylation // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0009060 // aerobic respiration // traceable author statement /// 0022900 // electron transport chain // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // traceable author statement /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200884_at NM_001823 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001823.1 /DEF=Homo sapiens creatine kinase, brain (CKB), mRNA. /FEA=mRNA /GEN=CKB /PROD=creatine kinase, brain /DB_XREF=gi:4502850 /UG=Hs.173724 creatine kinase, brain /FL=gb:L47647.1 gb:BC001190.1 gb:BC004914.1 gb:M16364.1 gb:M16451.1 gb:NM_001823.1 NM_001823 creatine kinase, brain CKB 1152 NM_001823 0006600 // creatine metabolic process // not recorded /// 0007420 // brain development // inferred from electronic annotation /// 0030644 // cellular chloride ion homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004111 // creatine kinase activity // traceable author statement /// 0004111 // creatine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016772 // transferase activity, transferring phosphorus-containing groups // inferred from electronic annotation 200885_at NM_005167 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005167.1 /DEF=Homo sapiens ras homolog gene family, member C (ARHC), mRNA. /FEA=mRNA /GEN=ARHC /PROD=ras homolog gene family, member C /DB_XREF=gi:4885066 /UG=Hs.179735 ras homolog gene family, member C /FL=gb:L25081.1 gb:NM_005167.1 NM_005167 ras homolog gene family, member C RHOC 389 NM_001042678 /// NM_001042679 /// NM_175744 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200886_s_at NM_002629 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002629.1 /DEF=Homo sapiens phosphoglycerate mutase 1 (brain) (PGAM1), mRNA. /FEA=mRNA /GEN=PGAM1 /PROD=phosphoglycerate mutase 1 (brain) /DB_XREF=gi:4505752 /UG=Hs.181013 phosphoglycerate mutase 1 (brain) /FL=gb:BC000455.1 gb:NM_002629.1 gb:J04173.1 NM_002629 phosphoglycerate mutase 1 (brain) PGAM1 5223 NM_002629 0006096 // glycolysis // inferred from electronic annotation /// 0006110 // regulation of glycolysis // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0043456 // regulation of pentose-phosphate shunt // inferred from direct assay /// 0045730 // respiratory burst // inferred from direct assay 0005829 // cytosol // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004082 // bisphosphoglycerate mutase activity // inferred from electronic annotation /// 0004083 // bisphosphoglycerate 2-phosphatase activity // inferred from electronic annotation /// 0004619 // phosphoglycerate mutase activity // inferred from mutant phenotype /// 0004619 // phosphoglycerate mutase activity // non-traceable author statement /// 0004619 // phosphoglycerate mutase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0016868 // intramolecular transferase activity, phosphotransferases // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 200887_s_at NM_007315 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007315.1 /DEF=Homo sapiens signal transducer and activator of transcription 1, 91kD (STAT1), mRNA. /FEA=mRNA /GEN=STAT1 /PROD=signal transducer and activator of transcription1, 91kD /DB_XREF=gi:6274551 /UG=Hs.21486 signal transducer and activator of transcription 1, 91kD /FL=gb:M97935.1 gb:NM_007315.1 NM_007315 signal transducer and activator of transcription 1, 91kDa STAT1 6772 NM_007315 /// NM_139266 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006919 // caspase activation // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007249 // I-kappaB kinase/NF-kappaB cascade // traceable author statement /// 0007259 // JAK-STAT cascade // traceable author statement /// 0007260 // tyrosine phosphorylation of STAT protein // traceable author statement /// 0009615 // response to virus // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005062 // hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200888_s_at NM_000978 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000978.1 /DEF=Homo sapiens ribosomal protein L23 (RPL23), mRNA. /FEA=mRNA /GEN=RPL23 /PROD=ribosomal protein L23 /DB_XREF=gi:4506604 /UG=Hs.234518 ribosomal protein L23 /FL=gb:NM_000978.1 NM_000978 ribosomal protein L23 RPL23 9349 NM_000978 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded /// 0006610 // ribosomal protein import into nucleus // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // non-traceable author statement 200889_s_at AI016620 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI016620 /FEA=EST /DB_XREF=gi:3230956 /DB_XREF=est:ov30e10.x1 /CLONE=IMAGE:1638858 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 AI016620 signal sequence receptor, alpha SSR1 6745 NM_003144 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005048 // signal sequence binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation 200890_s_at AW006345 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW006345 /FEA=EST /DB_XREF=gi:5855123 /DB_XREF=est:wt04d05.x1 /CLONE=IMAGE:2506473 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 AW006345 signal sequence receptor, alpha SSR1 6745 NM_003144 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005048 // signal sequence binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation 200891_s_at NM_003144 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003144.2 /DEF=Homo sapiens signal sequence receptor, alpha (translocon-associated protein alpha) (SSR1), mRNA. /FEA=mRNA /GEN=SSR1 /PROD=signal sequence receptor, alpha /DB_XREF=gi:6552340 /UG=Hs.250773 signal sequence receptor, alpha (translocon-associated protein alpha) /FL=gb:AF156965.1 gb:NM_003144.2 NM_003144 signal sequence receptor, alpha SSR1 6745 NM_003144 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005048 // signal sequence binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation 200892_s_at BC000451 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000451.1 /DEF=Homo sapiens, splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10, clone MGC:8454, mRNA, complete cds. /FEA=mRNA /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:12653362 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1 BC000451 splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) SFRS10 6434 NM_004593 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200893_at NM_004593 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004593.1 /DEF=Homo sapiens splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 (SFRS10), mRNA. /FEA=mRNA /GEN=SFRS10 /PROD=splicing factor, arginineserine-rich(transformer 2 Drosophila homolog) 10 /DB_XREF=gi:4759097 /UG=Hs.30035 splicing factor, arginineserine-rich (transformer 2 Drosophila homolog) 10 /FL=gb:BC000160.1 gb:BC000451.1 gb:U61267.1 gb:U68063.1 gb:NM_004593.1 NM_004593 splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) SFRS10 6434 NM_004593 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 200894_s_at AA894574 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA894574 /FEA=EST /DB_XREF=gi:3030975 /DB_XREF=est:of91h10.s1 /CLONE=IMAGE:1437763 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1 AA894574 FK506 binding protein 4, 59kDa FKBP4 2288 NM_002014 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 200895_s_at NM_002014 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002014.1 /DEF=Homo sapiens FK506-binding protein 4 (59kD) (FKBP4), mRNA. /FEA=mRNA /GEN=FKBP4 /PROD=FK506-binding protein 4 (59kD) /DB_XREF=gi:4503728 /UG=Hs.848 FK506-binding protein 4 (59kD) /FL=gb:BC001786.1 gb:M88279.1 gb:NM_002014.1 NM_002014 FK506 binding protein 4, 59kDa FKBP4 2288 NM_002014 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006463 // steroid hormone receptor complex assembly // inferred from electronic annotation /// 0006825 // copper ion transport // inferred from electronic annotation /// 0007566 // embryo implantation // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from electronic annotation /// 0046661 // male sex differentiation // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0005528 // FK506 binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // traceable author statement /// 0031072 // heat shock protein binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from electronic annotation /// 0051219 // phosphoprotein binding // inferred from electronic annotation 200896_x_at NM_004494 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004494.1 /DEF=Homo sapiens hepatoma-derived growth factor (high-mobility group protein 1-like) (HDGF), mRNA. /FEA=mRNA /GEN=HDGF /PROD=hepatoma-derived growth factor (high-mobilitygroup protein 1-like) /DB_XREF=gi:4758515 /UG=Hs.89525 hepatoma-derived growth factor (high-mobility group protein 1-like) /FL=gb:NM_004494.1 gb:D16431.1 NM_004494 hepatoma-derived growth factor (high-mobility group protein 1-like) HDGF 3068 NM_001126050 /// NM_001126051 /// NM_004494 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008201 // heparin binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation 200897_s_at NM_016081 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016081.1 /DEF=Homo sapiens palladin (KIAA0992), mRNA. /FEA=mRNA /GEN=KIAA0992 /PROD=palladin /DB_XREF=gi:7706354 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 NM_016081 palladin, cytoskeletal associated protein PALLD 23022 NM_016081 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // traceable author statement 200898_s_at AK002091 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK002091.1 /DEF=Homo sapiens cDNA FLJ11229 fis, clone PLACE1008356, highly similar to Homo sapiens mRNA for KIAA0679 protein. /FEA=mRNA /DB_XREF=gi:7023763 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1 AK002091 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 0006516 // glycoprotein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 200899_s_at NM_012215 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012215.1 /DEF=Homo sapiens meningioma expressed antigen 5 (hyaluronidase) (MGEA5), mRNA. /FEA=mRNA /GEN=MGEA5 /PROD=meningioma expressed antigen 5 (hyaluronidase) /DB_XREF=gi:11024697 /UG=Hs.5734 meningioma expressed antigen 5 (hyaluronidase) /FL=gb:AF036144.2 gb:NM_012215.1 NM_012215 meningioma expressed antigen 5 (hyaluronidase) MGEA5 10724 NM_001142434 /// NM_012215 0006516 // glycoprotein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004402 // histone acetyltransferase activity // inferred from electronic annotation /// 0004415 // hyalurononglucosaminidase activity // traceable author statement /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation 200900_s_at AI583537 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI583537 /FEA=EST /DB_XREF=gi:4569434 /DB_XREF=est:ts12d03.x1 /CLONE=IMAGE:2228357 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1 AI583537 mannose-6-phosphate receptor (cation dependent) M6PR 4074 NM_002355 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation 200901_s_at NM_002355 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002355.2 /DEF=Homo sapiens mannose-6-phosphate receptor (cation dependent) (M6PR), mRNA. /FEA=mRNA /GEN=M6PR /PROD=cation-dependent mannose-6-phosphate receptorprecursor /DB_XREF=gi:10947032 /UG=Hs.75709 mannose-6-phosphate receptor (cation dependent) /FL=gb:NM_002355.2 gb:M16985.1 NM_002355 mannose-6-phosphate receptor (cation dependent) M6PR 4074 NM_002355 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0008333 // endosome to lysosome transport // traceable author statement /// 0015761 // mannose transport // inferred from electronic annotation 0000323 // lytic vacuole // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004888 // transmembrane receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation /// 0015578 // mannose transmembrane transporter activity // inferred from electronic annotation 200902_at NM_004261 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004261.1 /DEF=Homo sapiens 15 kDa selenoprotein (SEP15), mRNA. /FEA=mRNA /GEN=SEP15 /PROD=15 kDa selenoprotein /DB_XREF=gi:4759095 /UG=Hs.90606 15 kDa selenoprotein /FL=gb:AF288991.1 gb:BC005294.1 gb:AF051894.1 gb:NM_004261.1 NM_004261 15 kDa selenoprotein SEP15 9403 NM_004261 /// NM_203341 0051084 // 'de novo' posttranslational protein folding // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from direct assay /// 0008430 // selenium binding // inferred from electronic annotation 200903_s_at NM_000687 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000687.1 /DEF=Homo sapiens S-adenosylhomocysteine hydrolase (AHCY), mRNA. /FEA=mRNA /GEN=AHCY /PROD=S-adenosylhomocysteine hydrolase /DB_XREF=gi:9951914 /UG=Hs.172673 S-adenosylhomocysteine hydrolase /FL=gb:M61832.1 gb:NM_000687.1 NM_000687 S-adenosylhomocysteine hydrolase AHCY 191 NM_000687 0006730 // one-carbon compound metabolic process // non-traceable author statement /// 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004013 // adenosylhomocysteinase activity // traceable author statement /// 0004013 // adenosylhomocysteinase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 200904_at X56841 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:X56841.1 /DEF=H.sapiens HLA-E gene. /FEA=mRNA /GEN=HLA-E /PROD=HLA-E /DB_XREF=gi:433491 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1 X56841 major histocompatibility complex, class I, E HLA-E 3133 NM_005516 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0032393 // MHC class I receptor activity // traceable author statement 200905_x_at NM_005516 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005516.1 /DEF=Homo sapiens major histocompatibility complex, class I, E (HLA-E), mRNA. /FEA=mRNA /GEN=HLA-E /PROD=major histocompatibility complex, class I, E /DB_XREF=gi:5031744 /UG=Hs.181392 major histocompatibility complex, class I, E /FL=gb:BC002578.1 gb:NM_005516.1 NM_005516 major histocompatibility complex, class I, E HLA-E 3133 NM_005516 0002474 // antigen processing and presentation of peptide antigen via MHC class I // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0019882 // antigen processing and presentation // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042612 // MHC class I protein complex // inferred from electronic annotation 0032393 // MHC class I receptor activity // traceable author statement 200906_s_at AK025843 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK025843.1 /DEF=Homo sapiens cDNA: FLJ22190 fis, clone HRC01053. /FEA=mRNA /DB_XREF=gi:10438481 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 AK025843 palladin, cytoskeletal associated protein PALLD 23022 NM_016081 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // traceable author statement 200907_s_at AU157932 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU157932 /FEA=EST /DB_XREF=gi:11019453 /DB_XREF=est:AU157932 /CLONE=PLACE1010217 /UG=Hs.194431 palladin /FL=gb:AF077041.1 gb:AF151909.1 gb:NM_016081.1 AU157932 palladin, cytoskeletal associated protein PALLD 23022 NM_016081 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0007010 // cytoskeleton organization // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005884 // actin filament // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation /// 0051371 // muscle alpha-actinin binding // traceable author statement 200908_s_at BC005354 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BC005354.1 /DEF=Homo sapiens, ribosomal protein, large P2, clone MGC:12453, mRNA, complete cds. /FEA=mRNA /PROD=ribosomal protein, large P2 /DB_XREF=gi:13529169 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1 BC005354 ribosomal protein, large, P2 RPLP2 6181 NM_001004 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200909_s_at NM_001004 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001004.1 /DEF=Homo sapiens ribosomal protein, large P2 (RPLP2), mRNA. /FEA=mRNA /GEN=RPLP2 /PROD=ribosomal protein, large P2 /DB_XREF=gi:4506670 /UG=Hs.119500 ribosomal protein, large P2 /FL=gb:BC005354.1 gb:M17887.1 gb:NM_001004.1 NM_001004 ribosomal protein, large, P2 RPLP2 6181 NM_001004 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 200910_at NM_005998 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005998.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 3 (gamma) (CCT3), mRNA. /FEA=mRNA /GEN=CCT3 /PROD=chaperonin containing TCP1, subunit 3 (gamma) /DB_XREF=gi:5174726 /UG=Hs.1708 chaperonin containing TCP1, subunit 3 (gamma) /FL=gb:NM_005998.1 NM_005998 chaperonin containing TCP1, subunit 3 (gamma) CCT3 7203 NM_001008800 /// NM_001008883 /// NM_005998 0006457 // protein folding // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 200911_s_at NM_006283 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006283.1 /DEF=Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), mRNA. /FEA=mRNA /GEN=TACC1 /PROD=transforming, acidic coiled-coil containingprotein 1 /DB_XREF=gi:5454099 /UG=Hs.173159 transforming, acidic coiled-coil containing protein 1 /FL=gb:AF049910.1 gb:NM_006283.1 NM_006283 transforming, acidic coiled-coil containing protein 1 TACC1 6867 NM_001122824 /// NM_006283 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200912_s_at NM_001967 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001967.2 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 2 (EIF4A2), mRNA. /FEA=mRNA /GEN=EIF4A2 /PROD=eukaryotic translation initiation factor 4A,isoform 2 /DB_XREF=gi:9945313 /UG=Hs.173912 eukaryotic translation initiation factor 4A, isoform 2 /FL=gb:D30655.1 gb:NM_001967.2 NM_001967 eukaryotic translation initiation factor 4A, isoform 2 EIF4A2 1974 NM_001967 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005829 // cytosol // not recorded /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 200913_at NM_002707 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002707.1 /DEF=Homo sapiens protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform (PPM1G), mRNA. /FEA=mRNA /GEN=PPM1G /PROD=protein phosphatase 1G (formerly 2C),magnesium-dependent, gamma isoform /DB_XREF=gi:4505998 /UG=Hs.17883 protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform /FL=gb:BC000057.1 gb:NM_002707.1 NM_002707 protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform PPM1G 5496 NM_002707 /// NM_177983 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007050 // cell cycle arrest // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008287 // protein serine/threonine phosphatase complex // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200914_x_at BF589024 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF589024 /FEA=EST /DB_XREF=gi:11681348 /DB_XREF=est:naa40c08.x1 /CLONE=IMAGE:3258639 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1 BF589024 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_004986 /// NM_182926 0007018 // microtubule-based movement // non-traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation 200915_x_at NM_004986 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004986.1 /DEF=Homo sapiens kinectin 1 (kinesin receptor) (KTN1), mRNA. /FEA=mRNA /GEN=KTN1 /PROD=kinectin 1 (kinesin receptor) /DB_XREF=gi:4826813 /UG=Hs.211577 kinectin 1 (kinesin receptor) /FL=gb:D13629.1 gb:L25616.1 gb:NM_004986.1 NM_004986 kinectin 1 (kinesin receptor) KTN1 3895 NM_001079521 /// NM_001079522 /// NM_004986 /// NM_182926 0007018 // microtubule-based movement // non-traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation 200916_at NM_003564 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003564.1 /DEF=Homo sapiens transgelin 2 (TAGLN2), mRNA. /FEA=mRNA /GEN=TAGLN2 /PROD=transgelin 2 /DB_XREF=gi:4507356 /UG=Hs.75725 transgelin 2 /FL=gb:D21261.1 gb:NM_003564.1 NM_003564 transgelin 2 TAGLN2 8407 NM_003564 0007517 // muscle development // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay 200917_s_at BG474541 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG474541 /FEA=EST /DB_XREF=gi:13406818 /DB_XREF=est:602517313F1 /CLONE=IMAGE:4649162 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1 BG474541 signal recognition particle receptor (docking protein) SRPR 6734 NM_003139 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005785 // signal recognition particle receptor complex // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // traceable author statement /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 200918_s_at NM_003139 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003139.1 /DEF=Homo sapiens signal recognition particle receptor (docking protein) (SRPR), mRNA. /FEA=mRNA /GEN=SRPR /PROD=signal recognition particle receptor (dockingprotein) /DB_XREF=gi:4507222 /UG=Hs.75730 signal recognition particle receptor (docking protein) /FL=gb:BC001162.1 gb:NM_003139.1 NM_003139 signal recognition particle receptor (docking protein) SRPR 6734 NM_003139 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005785 // signal recognition particle receptor complex // traceable author statement /// 0005785 // signal recognition particle receptor complex // inferred from electronic annotation /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005047 // signal recognition particle binding // traceable author statement /// 0005047 // signal recognition particle binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 200919_at NM_004427 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004427.1 /DEF=Homo sapiens early development regulator 2 (homolog of polyhomeotic 2) (EDR2), mRNA. /FEA=mRNA /GEN=EDR2 /PROD=early development regulator 2 /DB_XREF=gi:4758241 /UG=Hs.75878 early development regulator 2 (homolog of polyhomeotic 2) /FL=gb:U89278.1 gb:NM_004427.1 NM_004427 polyhomeotic homolog 2 (Drosophila) PHC2 1912 NM_004427 /// NM_198040 0007275 // multicellular organismal development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 200920_s_at AL535380 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL535380 /FEA=EST /DB_XREF=gi:12798873 /DB_XREF=est:AL535380 /CLONE=CS0DF009YN13 (5 prime) /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1 AL535380 B-cell translocation gene 1, anti-proliferative BTG1 694 NM_001731 0006479 // protein amino acid methylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0042981 // regulation of apoptosis // inferred from mutant phenotype /// 0045449 // regulation of transcription // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200921_s_at NM_001731 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001731.1 /DEF=Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA. /FEA=mRNA /GEN=BTG1 /PROD=B-cell translocation protein 1 /DB_XREF=gi:4502472 /UG=Hs.77054 B-cell translocation gene 1, anti-proliferative /FL=gb:NM_001731.1 NM_001731 B-cell translocation gene 1, anti-proliferative BTG1 694 NM_001731 0006479 // protein amino acid methylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from direct assay /// 0016477 // cell migration // non-traceable author statement /// 0030308 // negative regulation of cell growth // non-traceable author statement /// 0042981 // regulation of apoptosis // inferred from mutant phenotype /// 0045449 // regulation of transcription // non-traceable author statement /// 0045603 // positive regulation of endothelial cell differentiation // inferred from mutant phenotype /// 0045663 // positive regulation of myoblast differentiation // non-traceable author statement /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005737 // cytoplasm // inferred from direct assay 0003712 // transcription cofactor activity // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019899 // enzyme binding // inferred from physical interaction /// 0019900 // kinase binding // non-traceable author statement 200922_at NM_006801 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006801.1 /DEF=Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (KDELR1), mRNA. /FEA=mRNA /GEN=KDELR1 /PROD=KDEL receptor 1 /DB_XREF=gi:5803047 /UG=Hs.78040 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 /FL=gb:NM_006801.1 NM_006801 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 KDELR1 10945 NM_006801 0006621 // protein retention in ER lumen // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005046 // KDEL sequence binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0046923 // ER retention sequence binding // inferred from electronic annotation 200923_at NM_005567 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005567.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) (LGALS3BP), mRNA. /FEA=mRNA /GEN=LGALS3BP /PROD=galectin 6 binding protein /DB_XREF=gi:6006016 /UG=Hs.79339 lectin, galactoside-binding, soluble, 3 binding protein (galectin 6 binding protein) /FL=gb:BC002403.1 gb:BC002998.1 gb:L13210.1 gb:NM_005567.2 NM_005567 lectin, galactoside-binding, soluble, 3 binding protein LGALS3BP 3959 NM_005567 0006968 // cellular defense response // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005044 // scavenger receptor activity // traceable author statement /// 0005044 // scavenger receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200924_s_at NM_002394 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002394.1 /DEF=Homo sapiens solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (SLC3A2), mRNA. /FEA=mRNA /GEN=SLC3A2 /PROD=antigen identified by monoclonal antibodies 4F2,TRA1.10, TROP4, and T43 /DB_XREF=gi:4505140 /UG=Hs.79748 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 /FL=gb:BC001061.1 gb:J02769.1 gb:J03569.1 gb:NM_002394.1 gb:AB018010.1 NM_002394 hypothetical protein LOC442497 /// solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 LOC442497 /// SLC3A2 442497 /// 6520 NM_001012661 /// NM_001012662 /// NM_001012663 /// NM_001012664 /// NM_001013251 /// NM_002394 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006816 // calcium ion transport // non-traceable author statement /// 0006865 // amino acid transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0015827 // tryptophan transport // inferred from sequence or structural similarity /// 0016049 // cell growth // non-traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // non-traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005432 // calcium:sodium antiporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0043169 // cation binding // inferred from electronic annotation 200925_at NM_004373 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004373.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIa polypeptide 1 (COX6A1), mRNA. /FEA=mRNA /GEN=COX6A1 /PROD=cytochrome c oxidase subunit VIa polypeptide 1 /DB_XREF=gi:10047079 /UG=Hs.180714 cytochrome c oxidase subunit VIa polypeptide 1 /FL=gb:NM_004373.1 NM_004373 cytochrome c oxidase subunit VIa polypeptide 1 COX6A1 1337 NM_004373 0006091 // generation of precursor metabolites and energy // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 200926_at NM_001025 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001025.1 /DEF=Homo sapiens ribosomal protein S23 (RPS23), mRNA. /FEA=mRNA /GEN=RPS23 /PROD=ribosomal protein S23 /DB_XREF=gi:4506700 /UG=Hs.3463 ribosomal protein S23 /FL=gb:D14530.1 gb:NM_001025.1 NM_001025 ribosomal protein S23 RPS23 6228 NM_001025 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 200927_s_at AA919115 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA919115 /FEA=EST /DB_XREF=gi:3059005 /DB_XREF=est:ol85g11.s1 /CLONE=IMAGE:1536452 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AA919115 RAB14, member RAS oncogene family RAB14 51552 NM_016322 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // traceable author statement /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0046907 // intracellular transport // non-traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005624 // membrane fraction // inferred from sequence or structural similarity /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0042175 // nuclear envelope-endoplasmic reticulum network // inferred from sequence or structural similarity /// 0042175 // nuclear envelope-endoplasmic reticulum network // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200928_s_at AL162081 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AL162081.1 /DEF=Homo sapiens mRNA; cDNA DKFZp762K0911 (from clone DKFZp762K0911); complete cds. /FEA=mRNA /GEN=DKFZp762K0911 /PROD=hypothetical protein /DB_XREF=gi:7328165 /UG=Hs.5807 GTPase Rab14 /FL=gb:AF152463.1 gb:AF203689.1 gb:AL162081.1 gb:NM_016322.1 AL162081 RAB14, member RAS oncogene family RAB14 51552 NM_016322 0006810 // transport // inferred from electronic annotation /// 0006895 // Golgi to endosome transport // traceable author statement /// 0007264 // small GTPase mediated signal transduction // non-traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007269 // neurotransmitter secretion // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0046907 // intracellular transport // non-traceable author statement 0005622 // intracellular // inferred from direct assay /// 0005624 // membrane fraction // inferred from sequence or structural similarity /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from sequence or structural similarity /// 0005791 // rough endoplasmic reticulum // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from sequence or structural similarity /// 0005795 // Golgi stack // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from sequence or structural similarity /// 0030140 // trans-Golgi network transport vesicle // inferred from electronic annotation /// 0042175 // nuclear envelope-endoplasmic reticulum network // inferred from sequence or structural similarity /// 0042175 // nuclear envelope-endoplasmic reticulum network // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 200929_at NM_006827 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006827.1 /DEF=Homo sapiens transmembrane trafficking protein (TMP21), mRNA. /FEA=mRNA /GEN=TMP21 /PROD=transmembrane trafficking protein /DB_XREF=gi:5803200 /UG=Hs.74137 transmembrane trafficking protein /FL=gb:BC001825.1 gb:NM_006827.1 NM_006827 transmembrane emp24-like trafficking protein 10 (yeast) TMED10 10972 NM_006827 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0045055 // regulated secretory pathway // inferred from sequence or structural similarity /// 0045055 // regulated secretory pathway // inferred from electronic annotation /// 0048199 // vesicle targeting, to, from or within Golgi // inferred from sequence or structural similarity /// 0048199 // vesicle targeting, to, from or within Golgi // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from sequence or structural similarity /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005801 // cis-Golgi network // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from sequence or structural similarity /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from sequence or structural similarity 0005515 // protein binding // inferred from physical interaction 200930_s_at AA156675 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA156675 /FEA=EST /DB_XREF=gi:1728354 /DB_XREF=est:zl18h03.s1 /CLONE=IMAGE:502325 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1 AA156675 vinculin VCL 7414 NM_003373 /// NM_014000 0006928 // cell motion // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0043297 // apical junction assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction 200931_s_at NM_014000 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014000.1 /DEF=Homo sapiens vinculin (VCL), transcript variant meta-VCL, mRNA. /FEA=mRNA /GEN=VCL /PROD=VCL isoform meta-VCL /DB_XREF=gi:7669549 /UG=Hs.75350 vinculin /FL=gb:NM_014000.1 NM_014000 vinculin VCL 7414 NM_003373 /// NM_014000 0006928 // cell motion // traceable author statement /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030032 // lamellipodium assembly // inferred from sequence or structural similarity /// 0030032 // lamellipodium assembly // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // traceable author statement /// 0043297 // apical junction assembly // inferred from mutant phenotype 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from sequence or structural similarity /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from sequence or structural similarity /// 0005912 // adherens junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from sequence or structural similarity /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030055 // cell-substrate junction // non-traceable author statement /// 0043034 // costamere // inferred from sequence or structural similarity /// 0043034 // costamere // inferred from direct assay /// 0043034 // costamere // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay 0003779 // actin binding // inferred from direct assay /// 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016491 // oxidoreductase activity // inferred from sequence or structural similarity /// 0045294 // alpha-catenin binding // inferred from physical interaction 200932_s_at NM_006400 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006400.2 /DEF=Homo sapiens dynactin 2 (p50) (DCTN2), mRNA. /FEA=mRNA /GEN=DCTN2 /PROD=dynactin 2 /DB_XREF=gi:13259506 /UG=Hs.84153 dynactin 2 (p50) /FL=gb:U50733.1 gb:BC000718.1 gb:NM_006400.2 NM_006400 dynactin 2 (p50) DCTN2 10540 NM_006400 0007017 // microtubule-based process // inferred from electronic annotation /// 0007067 // mitosis // inferred from mutant phenotype /// 0008283 // cell proliferation // inferred from mutant phenotype 0000776 // kinetochore // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005869 // dynactin complex // inferred from direct assay /// 0005869 // dynactin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200933_x_at NM_001007 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001007.1 /DEF=Homo sapiens ribosomal protein S4, X-linked (RPS4X), mRNA. /FEA=mRNA /GEN=RPS4X /PROD=ribosomal protein S4, X-linked /DB_XREF=gi:4506724 /UG=Hs.108124 ribosomal protein S4, X-linked /FL=gb:BC000472.1 gb:BC002569.1 gb:M58458.1 gb:M22146.1 gb:NM_001007.1 NM_001007 ribosomal protein S4, X-linked RPS4X 6191 NM_001007 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006414 // translational elongation // not recorded /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0045727 // positive regulation of translation // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from direct assay /// 0005840 // ribosome // inferred from electronic annotation /// 0005844 // polysome // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from mutant phenotype /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 200934_at NM_003472 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003472.1 /DEF=Homo sapiens DEK oncogene (DNA binding) (DEK), mRNA. /FEA=mRNA /GEN=DEK /PROD=DEK oncogene (DNA binding) /DB_XREF=gi:4503248 /UG=Hs.110713 DEK oncogene (DNA binding) /FL=gb:NM_003472.1 NM_003472 DEK oncogene DEK 7913 NM_001134709 /// NM_003472 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0019079 // viral genome replication // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003704 // specific RNA polymerase II transcription factor activity // traceable author statement /// 0042393 // histone binding // inferred from direct assay 200935_at NM_004343 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004343.2 /DEF=Homo sapiens calreticulin (CALR), mRNA. /FEA=mRNA /GEN=CALR /PROD=calreticulin precursor /DB_XREF=gi:5921996 /UG=Hs.16488 calreticulin /FL=gb:BC002500.1 gb:M84739.1 gb:M32294.1 gb:NM_004343.2 NM_004343 calreticulin CALR 811 NM_004343 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002502 // peptide antigen assembly with MHC class I protein complex // inferred from sequence or structural similarity /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0006611 // protein export from nucleus // inferred from direct assay /// 0006874 // cellular calcium ion homeostasis // traceable author statement /// 0007050 // cell cycle arrest // inferred from genetic interaction /// 0008284 // positive regulation of cell proliferation // inferred from genetic interaction /// 0010149 // senescence // inferred from genetic interaction /// 0017148 // negative regulation of translation // inferred from sequence or structural similarity /// 0017148 // negative regulation of translation // traceable author statement /// 0022417 // protein maturation via protein folding // traceable author statement /// 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation /// 0033144 // negative regulation of steroid hormone receptor signaling pathway // inferred from direct assay /// 0040020 // regulation of meiosis // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // traceable author statement /// 0042981 // regulation of apoptosis // traceable author statement /// 0045665 // negative regulation of neuron differentiation // inferred from direct assay /// 0045740 // positive regulation of DNA replication // inferred from genetic interaction /// 0045787 // positive regulation of cell cycle // inferred from genetic interaction /// 0048387 // negative regulation of retinoic acid receptor signaling pathway // inferred from direct assay /// 0050766 // positive regulation of phagocytosis // inferred from sequence or structural similarity /// 0050821 // protein stabilization // traceable author statement /// 0051208 // sequestering of calcium ion // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005844 // polysome // inferred from sequence or structural similarity /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from electronic annotation /// 0009986 // cell surface // traceable author statement /// 0042824 // MHC class I peptide loading complex // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0001849 // complement component C1q binding // traceable author statement /// 0003677 // DNA binding // non-traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0005178 // integrin binding // inferred from physical interaction /// 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005529 // sugar binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0016564 // transcription repressor activity // inferred from direct assay /// 0030246 // carbohydrate binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // inferred from direct assay /// 0051082 // unfolded protein binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051087 // chaperone binding // traceable author statement 200936_at NM_000973 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000973.1 /DEF=Homo sapiens ribosomal protein L8 (RPL8), mRNA. /FEA=mRNA /GEN=RPL8 /PROD=ribosomal protein L8 /DB_XREF=gi:4506662 /UG=Hs.178551 ribosomal protein L8 /FL=gb:BC000077.1 gb:NM_000973.1 NM_000973 ribosomal protein L8 RPL8 6132 NM_000973 /// NM_033301 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 200937_s_at NM_000969 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000969.1 /DEF=Homo sapiens ribosomal protein L5 (RPL5), mRNA. /FEA=mRNA /GEN=RPL5 /PROD=ribosomal protein L5 /DB_XREF=gi:4506654 /UG=Hs.180946 ribosomal protein L5 /FL=gb:AF113210.1 gb:NM_000969.1 gb:U14966.1 NM_000969 ribosomal protein L5 RPL5 6125 NM_000969 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0042273 // ribosomal large subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008097 // 5S rRNA binding // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation 200938_s_at AI920976 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI920976 /FEA=EST /DB_XREF=gi:5656940 /DB_XREF=est:wo16h05.x1 /CLONE=IMAGE:2455545 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 AI920976 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006607 // NLS-bearing substrate import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // non-traceable author statement /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200939_s_at NM_012102 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012102.1 /DEF=Homo sapiens arginine-glutamic acid dipeptide (RE) repeats (RERE), mRNA. /FEA=mRNA /GEN=RERE /PROD=arginine-glutamic acid dipeptide (RE) repeats /DB_XREF=gi:6912253 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 NM_012102 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006607 // NLS-bearing substrate import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // non-traceable author statement /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200940_s_at AB036737 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB036737.1 /DEF=Homo sapiens mRNA for RERE, complete cds. /FEA=mRNA /PROD=RERE /DB_XREF=gi:8096339 /UG=Hs.194369 arginine-glutamic acid dipeptide (RE) repeats /FL=gb:AF118275.1 gb:NM_012102.1 gb:AB036737.1 AB036737 arginine-glutamic acid dipeptide (RE) repeats RERE 473 NM_001042681 /// NM_001042682 /// NM_012102 0006338 // chromatin remodeling // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006607 // NLS-bearing substrate import into nucleus // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation 0000118 // histone deacetylase complex // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // non-traceable author statement /// 0008267 // poly-glutamine tract binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200941_at AK026575 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK026575.1 /DEF=Homo sapiens cDNA: FLJ22922 fis, clone KAT06722. /FEA=mRNA /DB_XREF=gi:10439459 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1 AK026575 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200942_s_at NM_001537 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001537.1 /DEF=Homo sapiens heat shock factor binding protein 1 (HSBP1), mRNA. /FEA=mRNA /GEN=HSBP1 /PROD=heat shock factor binding protein 1 /DB_XREF=gi:4557646 /UG=Hs.250899 heat shock factor binding protein 1 /FL=gb:AF068754.1 gb:NM_001537.1 NM_001537 heat shock factor binding protein 1 HSBP1 3281 NM_001537 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003714 // transcription corepressor activity // traceable author statement 200943_at NM_004965 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1 NM_004965 high-mobility group nucleosome binding domain 1 HMGN1 3150 NM_004965 0000785 // chromatin // traceable author statement /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0008159 // positive transcription elongation factor activity // traceable author statement 200944_s_at NM_004965 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004965.1 /DEF=Homo sapiens high-mobility group (nonhistone chromosomal) protein 14 (HMG14), mRNA. /FEA=mRNA /GEN=HMG14 /PROD=high-mobility group (nonhistone chromosomal)protein 14 /DB_XREF=gi:4826757 /UG=Hs.251064 high-mobility group (nonhistone chromosomal) protein 14 /FL=gb:BC000075.1 gb:J02621.1 gb:NM_004965.1 NM_004965 high-mobility group nucleosome binding domain 1 /// high-mobility group nucleosome binding domain 1 pseudogene HMGN1 /// LOC643790 3150 /// 643790 NM_004965 0000785 // chromatin // traceable author statement /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0008159 // positive transcription elongation factor activity // traceable author statement 200945_s_at NM_014933 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014933.1 /DEF=Homo sapiens yeast Sec31p homolog (KIAA0905), mRNA. /FEA=mRNA /GEN=KIAA0905 /PROD=yeast Sec31p homolog /DB_XREF=gi:7662369 /UG=Hs.70266 yeast Sec31p homolog /FL=gb:AB018359.1 gb:NM_014933.1 gb:AF139184.1 NM_014933 SEC31 homolog A (S. cerevisiae) SEC31A 22872 NM_001077206 /// NM_001077207 /// NM_001077208 /// NM_014933 /// NM_016211 0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // not recorded /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // non-traceable author statement /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200946_x_at AI339331 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI339331 /FEA=EST /DB_XREF=gi:4076258 /DB_XREF=est:qt01g12.x1 /CLONE=IMAGE:1946374 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1 AI339331 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 200947_s_at NM_005271 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005271.1 /DEF=Homo sapiens glutamate dehydrogenase 1 (GLUD1), mRNA. /FEA=mRNA /GEN=GLUD1 /PROD=glutamate dehydrogenase 1 /DB_XREF=gi:4885280 /UG=Hs.77508 glutamate dehydrogenase 1 /FL=gb:J03248.1 gb:M37154.1 gb:M20867.1 gb:NM_005271.1 NM_005271 glutamate dehydrogenase 1 GLUD1 2746 NM_005271 0006520 // amino acid metabolic process // inferred from electronic annotation /// 0006538 // glutamate catabolic process // inferred from direct assay /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004352 // glutamate dehydrogenase activity // inferred from direct assay /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // not recorded /// 0004353 // glutamate dehydrogenase [NAD(P)+] activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 200948_at NM_005439 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005439.1 /DEF=Homo sapiens myeloid leukemia factor 2 (MLF2), mRNA. /FEA=mRNA /GEN=MLF2 /PROD=myeloid leukemia factor 2 /DB_XREF=gi:4885486 /UG=Hs.79026 myeloid leukemia factor 2 /FL=gb:BC000898.1 gb:BC002340.1 gb:U57342.1 gb:AF070539.1 gb:NM_005439.1 NM_005439 myeloid leukemia factor 2 MLF2 8079 NM_005439 /// NR_026581 0006952 // defense response // inferred from mutant phenotype 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 200949_x_at NM_001023 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001023.1 /DEF=Homo sapiens ribosomal protein S20 (RPS20), mRNA. /FEA=mRNA /GEN=RPS20 /PROD=ribosomal protein S20 /DB_XREF=gi:4506696 /UG=Hs.8102 ribosomal protein S20 /FL=gb:L06498.1 gb:NM_001023.1 NM_001023 ribosomal protein S20 RPS20 6224 NM_001023 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200950_at NM_006409 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006409.1 /DEF=Homo sapiens actin related protein 23 complex, subunit 1A (41 kD) (ARPC1A), mRNA. /FEA=mRNA /GEN=ARPC1A /PROD=actin related protein 23 complex, subunit 1A(41 kD) /DB_XREF=gi:5454077 /UG=Hs.90370 actin related protein 23 complex, subunit 1A (41 kD) /FL=gb:NM_006409.1 NM_006409 actin related protein 2/3 complex, subunit 1A, 41kDa ARPC1A 10552 NM_006409 0030036 // actin cytoskeleton organization // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement 0003779 // actin binding // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200951_s_at AW026491 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW026491 /FEA=EST /DB_XREF=gi:5880021 /DB_XREF=est:wv14b06.x1 /CLONE=IMAGE:2529491 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AW026491 cyclin D2 CCND2 894 NM_001759 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001934 // positive regulation of protein amino acid phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 200952_s_at AI635187 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI635187 /FEA=EST /DB_XREF=gi:4686517 /DB_XREF=est:tz22b10.x1 /CLONE=IMAGE:2289307 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 AI635187 cyclin D2 CCND2 894 NM_001759 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001934 // positive regulation of protein amino acid phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 200953_s_at NM_001759 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001759.1 /DEF=Homo sapiens cyclin D2 (CCND2), mRNA. /FEA=mRNA /GEN=CCND2 /PROD=cyclin D2 /DB_XREF=gi:4502616 /UG=Hs.75586 cyclin D2 /FL=gb:M90813.1 gb:D13639.1 gb:NM_001759.1 NM_001759 cyclin D2 CCND2 894 NM_001759 0000082 // G1/S transition of mitotic cell cycle // inferred from electronic annotation /// 0001934 // positive regulation of protein amino acid phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from physical interaction 200954_at NM_001694 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001694.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD (ATP6L), mRNA. /FEA=mRNA /GEN=ATP6L /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 16kD /DB_XREF=gi:4502312 /UG=Hs.76159 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16kD /FL=gb:BC004537.1 gb:M62762.1 gb:NM_001694.1 NM_001694 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c ATP6V0C 527 NM_001694 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005773 // vacuole // inferred from electronic annotation /// 0005774 // vacuolar membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033177 // proton-transporting two-sector ATPase complex, proton-transporting domain // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism // traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 200955_at NM_006839 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006839.1 /DEF=Homo sapiens inner membrane protein, mitochondrial (mitofilin) (IMMT), mRNA. /FEA=mRNA /GEN=IMMT /PROD=inner membrane protein, mitochondrial(mitofilin) /DB_XREF=gi:5803114 /UG=Hs.78504 inner membrane protein, mitochondrial (mitofilin) /FL=gb:L42572.1 gb:BC002412.1 gb:D21094.1 gb:NM_006839.1 NM_006839 inner membrane protein, mitochondrial (mitofilin) IMMT 10989 NM_001100169 /// NM_001100170 /// NM_006839 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 200956_s_at BE795648 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE795648 /FEA=EST /DB_XREF=gi:10216846 /DB_XREF=est:601590631F1 /CLONE=IMAGE:3945006 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1 BE795648 structure specific recognition protein 1 SSRP1 6749 NM_003146 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200957_s_at NM_003146 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003146.1 /DEF=Homo sapiens structure specific recognition protein 1 (SSRP1), mRNA. /FEA=mRNA /GEN=SSRP1 /PROD=structure specific recognition protein 1 /DB_XREF=gi:4507240 /UG=Hs.79162 structure specific recognition protein 1 /FL=gb:BC005116.1 gb:M86737.1 gb:NM_003146.1 NM_003146 structure specific recognition protein 1 SSRP1 6749 NM_003146 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 200958_s_at NM_005625 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005625.1 /DEF=Homo sapiens syndecan binding protein (syntenin) (SDCBP), mRNA. /FEA=mRNA /GEN=SDCBP /PROD=syndecan binding protein (syntenin) /DB_XREF=gi:5032082 /UG=Hs.8180 syndecan binding protein (syntenin) /FL=gb:AF000652.1 gb:NM_005625.1 NM_005625 syndecan binding protein (syntenin) SDCBP 6386 NM_001007067 /// NM_001007068 /// NM_001007069 /// NM_001007070 /// NM_005625 0006612 // protein targeting to membrane // non-traceable author statement /// 0006930 // substrate-bound cell migration, cell extension // non-traceable author statement /// 0007242 // intracellular signaling cascade // non-traceable author statement /// 0007265 // Ras protein signal transduction // inferred from electronic annotation /// 0007268 // synaptic transmission // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005856 // cytoskeleton // non-traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005895 // interleukin-5 receptor complex // inferred from sequence or structural similarity /// 0005912 // adherens junction // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005137 // interleukin-5 receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0008093 // cytoskeletal adaptor activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0045545 // syndecan binding // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 200959_at NM_004960 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004960.1 /DEF=Homo sapiens fusion, derived from t(12;16) malignant liposarcoma (FUS), mRNA. /FEA=mRNA /GEN=FUS /PROD=fusion, derived from t(12;16) malignantliposarcoma /DB_XREF=gi:4826733 /UG=Hs.99969 fusion, derived from t(12;16) malignant liposarcoma /FL=gb:BC000402.1 gb:BC002459.1 gb:NM_004960.1 NM_004960 fusion (involved in t(12;16) in malignant liposarcoma) FUS 2521 NM_004960 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006974 // response to DNA damage stimulus // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006983 // ER overload response // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred from direct assay /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0043065 // positive regulation of apoptosis // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from direct assay /// 0045941 // positive regulation of transcription // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 200960_x_at NM_007096 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007096.1 /DEF=Homo sapiens clathrin, light polypeptide (Lca) (CLTA), transcript variant brain-specific, mRNA. /FEA=mRNA /GEN=CLTA /PROD=clathrin, light polypeptide A (Lca) isoform b /DB_XREF=gi:6005992 /UG=Hs.104143 clathrin, light polypeptide (Lca) /FL=gb:M20471.1 gb:NM_007096.1 NM_007096 clathrin, light chain (Lca) CLTA 1211 NM_001076677 /// NM_001833 /// NM_007096 0006886 // intracellular protein transport // non-traceable author statement /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005886 // plasma membrane // not recorded /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030118 // clathrin coat // non-traceable author statement /// 0030130 // clathrin coat of trans-Golgi network vesicle // inferred from electronic annotation /// 0030132 // clathrin coat of coated pit // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 200961_at NM_012248 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012248.1 /DEF=Homo sapiens selenophosphate synthetase 2 (SPS2), mRNA. /FEA=mRNA /GEN=SPS2 /PROD=selenophosphate synthetase 2 /DB_XREF=gi:7657612 /UG=Hs.118725 selenophosphate synthetase 2 /FL=gb:BC002381.1 gb:U43286.1 gb:NM_012248.1 NM_012248 selenophosphate synthetase 2 SEPHS2 22928 NM_012248 0016260 // selenocysteine biosynthetic process // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // inferred from electronic annotation /// 0004756 // selenide, water dikinase activity // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 200962_at AI348010 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI348010 /FEA=EST /DB_XREF=gi:4085216 /DB_XREF=est:qp61b10.x1 /CLONE=IMAGE:1927483 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1 AI348010 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200963_x_at NM_000993 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000993.1 /DEF=Homo sapiens ribosomal protein L31 (RPL31), mRNA. /FEA=mRNA /GEN=RPL31 /PROD=ribosomal protein L31 /DB_XREF=gi:4506632 /UG=Hs.184014 ribosomal protein L31 /FL=gb:NM_000993.1 NM_000993 ribosomal protein L31 RPL31 6160 NM_000993 /// NM_001098577 /// NM_001099693 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 200964_at NM_003334 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003334.1 /DEF=Homo sapiens ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) (UBE1), mRNA. /FEA=mRNA /GEN=UBE1 /PROD=ubiquitin-activating enzyme E1 (A1S9T and BN75temperature sensitivity complementing) /DB_XREF=gi:4507762 /UG=Hs.2055 ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing) /FL=gb:M58028.1 gb:NM_003334.1 NM_003334 ubiquitin-like modifier activating enzyme 1 UBA1 7317 NM_003334 /// NM_153280 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 200965_s_at NM_006720 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006720.1 /DEF=Homo sapiens actin binding LIM protein 1 (ABLIM), transcript variant ABLIM-s, mRNA. /FEA=mRNA /GEN=ABLIM /PROD=actin-binding LIM protein 1, isoform s /DB_XREF=gi:5921987 /UG=Hs.158203 actin binding LIM protein 1 /FL=gb:D31883.1 gb:NM_006720.1 NM_006720 actin binding LIM protein 1 ABLIM1 3983 NM_001003407 /// NM_001003408 /// NM_002313 /// NM_006720 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement /// 0009887 // organ morphogenesis // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 200966_x_at NM_000034 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000034.1 /DEF=Homo sapiens aldolase A, fructose-bisphosphate (ALDOA), mRNA. /FEA=mRNA /GEN=ALDOA /PROD=aldolase A /DB_XREF=gi:4557304 /UG=Hs.273415 aldolase A, fructose-bisphosphate /FL=gb:BC004333.1 gb:M11560.1 gb:NM_000034.1 NM_000034 aldolase A, fructose-bisphosphate ALDOA 226 NM_000034 /// NM_001127617 /// NM_184041 /// NM_184043 0006000 // fructose metabolic process // inferred from mutant phenotype /// 0006096 // glycolysis // inferred from electronic annotation /// 0006096 // glycolysis // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006941 // striated muscle contraction // inferred from mutant phenotype /// 0007015 // actin filament organization // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from direct assay /// 0030388 // fructose 1,6-bisphosphate metabolic process // inferred from direct assay /// 0046716 // muscle maintenance // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0031674 // I band // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay 0003779 // actin binding // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from electronic annotation /// 0004332 // fructose-bisphosphate aldolase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from direct assay /// 0015631 // tubulin binding // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0042802 // identical protein binding // traceable author statement /// 0070061 // fructose binding // inferred from direct assay 200967_at NM_000942 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1 NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0006457 // protein folding // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 200968_s_at NM_000942 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000942.1 /DEF=Homo sapiens peptidylprolyl isomerase B (cyclophilin B) (PPIB), mRNA. /FEA=mRNA /GEN=PPIB /PROD=peptidylprolyl isomerase B (cyclophilin B) /DB_XREF=gi:4758949 /UG=Hs.699 peptidylprolyl isomerase B (cyclophilin B) /FL=gb:BC001125.1 gb:M60857.1 gb:M63573.1 gb:NM_000942.1 NM_000942 peptidylprolyl isomerase B (cyclophilin B) PPIB 5479 NM_000942 0006457 // protein folding // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // non-traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // non-traceable author statement /// 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 200969_at BG107676 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG107676 /FEA=EST /DB_XREF=gi:12601522 /DB_XREF=est:602277844F1 /CLONE=IMAGE:4365370 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 BG107676 stress-associated endoplasmic reticulum protein 1 SERP1 27230 NM_014445 0006464 // protein modification process // traceable author statement /// 0006486 // protein amino acid glycosylation // traceable author statement /// 0006486 // protein amino acid glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200970_s_at AL136807 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AL136807.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434L1621 (from clone DKFZp434L1621); complete cds. /FEA=mRNA /GEN=DKFZp434L1621 /PROD=hypothetical protein /DB_XREF=gi:12053124 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 AL136807 stress-associated endoplasmic reticulum protein 1 SERP1 27230 NM_014445 0006464 // protein modification process // traceable author statement /// 0006486 // protein amino acid glycosylation // traceable author statement /// 0006486 // protein amino acid glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200971_s_at NM_014445 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014445.1 /DEF=Homo sapiens stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 (SERP1), mRNA. /FEA=mRNA /GEN=SERP1 /PROD=stress-associated endoplasmic reticulum protein1; ribosome associated membrane protein 4 /DB_XREF=gi:7657551 /UG=Hs.76698 stress-associated endoplasmic reticulum protein 1; ribosome associated membrane protein 4 /FL=gb:AL136807.1 gb:AF136975.1 gb:AB022427.1 gb:NM_014445.1 NM_014445 stress-associated endoplasmic reticulum protein 1 SERP1 27230 NM_014445 0006464 // protein modification process // traceable author statement /// 0006486 // protein amino acid glycosylation // traceable author statement /// 0006486 // protein amino acid glycosylation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0007009 // plasma membrane organization // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 200972_at BC000704 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000704.1 /DEF=Homo sapiens, tetraspan 3, clone MGC:965, mRNA, complete cds. /FEA=mRNA /PROD=tetraspan 3 /DB_XREF=gi:12653830 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1 BC000704 tetraspanin 3 TSPAN3 10099 NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 200973_s_at NM_005724 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005724.1 /DEF=Homo sapiens tetraspan 3 (TSPAN-3), mRNA. /FEA=mRNA /GEN=TSPAN-3 /PROD=tetraspan 3 /DB_XREF=gi:5032200 /UG=Hs.100090 tetraspan 3 /FL=gb:BC000704.1 gb:BC004280.1 gb:AF054840.1 gb:NM_005724.1 gb:AF133423.1 NM_005724 tetraspanin 3 TSPAN3 10099 NM_005724 /// NM_198902 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 200974_at NM_001613 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001613.1 /DEF=Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), mRNA. /FEA=mRNA /GEN=ACTA2 /PROD=alpha 2 actin /DB_XREF=gi:4501882 /UG=Hs.195851 actin, alpha 2, smooth muscle, aorta /FL=gb:J05192.1 gb:NM_001613.1 NM_001613 actin, alpha 2, smooth muscle, aorta ACTA2 59 NM_001141945 /// NM_001613 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0014829 // vascular smooth muscle contraction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200975_at NM_000310 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000310.1 /DEF=Homo sapiens palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) (PPT1), mRNA. /FEA=mRNA /GEN=PPT1 /PROD=palmitoyl-protein thioesterase 1(ceroid-lipofuscinosis, neuronal 1, infantile) /DB_XREF=gi:4506030 /UG=Hs.3873 palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) /FL=gb:U44772.1 gb:NM_000310.1 NM_000310 palmitoyl-protein thioesterase 1 PPT1 5538 NM_000310 /// NM_001142604 0002084 // protein depalmitoylation // inferred from direct assay /// 0002084 // protein depalmitoylation // inferred from sequence or structural similarity /// 0002084 // protein depalmitoylation // inferred from electronic annotation /// 0006309 // DNA fragmentation during apoptosis // inferred from direct assay /// 0006464 // protein modification process // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from mutant phenotype /// 0006907 // pinocytosis // inferred from mutant phenotype /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007042 // lysosomal lumen acidification // inferred from mutant phenotype /// 0007269 // neurotransmitter secretion // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0007420 // brain development // inferred from expression pattern /// 0007420 // brain development // inferred from mutant phenotype /// 0007601 // visual perception // inferred from electronic annotation /// 0007625 // grooming behavior // inferred from electronic annotation /// 0008306 // associative learning // inferred from electronic annotation /// 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0015031 // protein transport // inferred from mutant phenotype /// 0016042 // lipid catabolic process // inferred from direct assay /// 0030149 // sphingolipid catabolic process // traceable author statement /// 0030163 // protein catabolic process // non-traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0031579 // membrane raft organization // inferred from mutant phenotype /// 0032429 // regulation of phospholipase A2 activity // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from direct assay /// 0043524 // negative regulation of neuron apoptosis // inferred from mutant phenotype /// 0044257 // cellular protein catabolic process // inferred from electronic annotation /// 0048260 // positive regulation of receptor-mediated endocytosis // inferred from mutant phenotype /// 0048549 // positive regulation of pinocytosis // inferred from mutant phenotype /// 0048666 // neuron development // traceable author statement /// 0050803 // regulation of synapse structure and activity // non-traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051181 // cofactor transport // inferred from mutant phenotype /// 0051186 // cofactor metabolic process // inferred from mutant phenotype 0005576 // extracellular region // inferred from direct assay /// 0005576 // extracellular region // inferred from sequence or structural similarity /// 0005615 // extracellular space // inferred from electronic annotation /// 0005624 // membrane fraction // inferred from sequence or structural similarity /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0008021 // synaptic vesicle // inferred from direct assay /// 0030424 // axon // inferred from direct assay /// 0030424 // axon // inferred from electronic annotation /// 0030425 // dendrite // inferred from electronic annotation /// 0043025 // cell soma // inferred from electronic annotation /// 0045121 // membrane raft // inferred from direct assay 0008474 // palmitoyl-(protein) hydrolase activity // inferred from direct assay /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from mutant phenotype /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from sequence or structural similarity /// 0008474 // palmitoyl-(protein) hydrolase activity // inferred from electronic annotation /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from direct assay /// 0016290 // palmitoyl-CoA hydrolase activity // inferred from sequence or structural similarity /// 0016787 // hydrolase activity // inferred from electronic annotation 200976_s_at NM_006024 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006024.2 /DEF=Homo sapiens Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1), mRNA. /FEA=mRNA /GEN=TAX1BP1 /PROD=Tax1 (human T-cell leukemia virus type I)binding protein 1 /DB_XREF=gi:5803188 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1 NM_006024 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_006024 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200977_s_at AF090891 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF090891.1 /DEF=Homo sapiens clone HQ0105 PRO0105 mRNA, complete cds. /FEA=mRNA /PROD=PRO0105 /DB_XREF=gi:6690159 /UG=Hs.5437 Tax1 (human T-cell leukemia virus type I) binding protein 1 /FL=gb:U33821.2 gb:NM_006024.2 gb:AF090891.1 gb:AF268075.1 AF090891 Tax1 (human T-cell leukemia virus type I) binding protein 1 TAX1BP1 8887 NM_001079864 /// NM_006024 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200978_at NM_005917 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005917.1 /DEF=Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), mRNA. /FEA=mRNA /GEN=MDH1 /PROD=malate dehydrogenase 1, NAD (soluble) /DB_XREF=gi:5174538 /UG=Hs.75375 malate dehydrogenase 1, NAD (soluble) /FL=gb:D55654.1 gb:U20352.1 gb:NM_005917.1 NM_005917 malate dehydrogenase 1, NAD (soluble) MDH1 4190 NM_005917 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolysis // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006107 // oxaloacetate metabolic process // inferred from electronic annotation /// 0006108 // malate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019674 // NAD metabolic process // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004470 // malic enzyme activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016615 // malate dehydrogenase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030060 // L-malate dehydrogenase activity // not recorded /// 0030060 // L-malate dehydrogenase activity // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 200979_at BF739979 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF739979 /FEA=EST /DB_XREF=gi:12066655 /DB_XREF=est:7o41g06.x1 /CLONE=IMAGE:3576778 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1 BF739979 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 0006096 // glycolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004738 // pyruvate dehydrogenase activity // inferred from electronic annotation /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation 200980_s_at NM_000284 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000284.1 /DEF=Homo sapiens pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), mRNA. /FEA=mRNA /GEN=PDHA1 /PROD=pyruvate dehydrogenase (lipoamide) alpha 1 /DB_XREF=gi:4505684 /UG=Hs.1023 pyruvate dehydrogenase (lipoamide) alpha 1 /FL=gb:L48690.1 gb:BC002406.1 gb:J03575.1 gb:M24848.1 gb:L13318.1 gb:NM_000284.1 NM_000284 pyruvate dehydrogenase (lipoamide) alpha 1 PDHA1 5160 NM_000284 0006096 // glycolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from electronic annotation 0004738 // pyruvate dehydrogenase activity // inferred from electronic annotation /// 0004739 // pyruvate dehydrogenase (acetyl-transferring) activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation 200981_x_at NM_016592 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016592.1 /DEF=Homo sapiens neuroendocrine secretory protein 55 (NESP55), mRNA. /FEA=mRNA /GEN=NESP55 /PROD=neuroendocrine secretory protein 55 /DB_XREF=gi:7706588 /UG=Hs.113368 neuroendocrine secretory protein 55 /FL=gb:AF105253.1 gb:NM_016592.1 NM_016592 GNAS complex locus GNAS 2778 NM_000516 /// NM_001077488 /// NM_001077489 /// NM_001077490 /// NM_016592 /// NM_080425 /// NM_080426 /// NR_003259 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007189 // G-protein signaling, adenylate cyclase activating pathway // inferred from electronic annotation /// 0007189 // G-protein signaling, adenylate cyclase activating pathway // non-traceable author statement /// 0007190 // activation of adenylate cyclase activity // traceable author statement /// 0007565 // female pregnancy // non-traceable author statement /// 0007608 // sensory perception of smell // traceable author statement /// 0009306 // protein secretion // non-traceable author statement /// 0009755 // hormone-mediated signaling // not recorded /// 0046907 // intracellular transport // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // inferred from electronic annotation /// 0005834 // heterotrimeric G-protein complex // non-traceable author statement /// 0005834 // heterotrimeric G-protein complex // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031224 // intrinsic to membrane // inferred from direct assay /// 0031982 // vesicle // inferred from electronic annotation /// 0032588 // trans-Golgi network membrane // inferred from direct assay /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0005525 // GTP binding // non-traceable author statement /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation /// 0031852 // mu-type opioid receptor binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200982_s_at NM_001155 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001155.2 /DEF=Homo sapiens annexin A6 (ANXA6), transcript variant 1, mRNA. /FEA=mRNA /GEN=ANXA6 /PROD=annexin VI isoform 1 /DB_XREF=gi:4809274 /UG=Hs.118796 annexin A6 /FL=gb:J03578.1 gb:D00510.1 gb:NM_001155.2 NM_001155 annexin A6 ANXA6 309 NM_001155 /// NM_004033 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation 200983_x_at BF983379 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF983379 /FEA=EST /DB_XREF=gi:12386191 /DB_XREF=est:602305270F1 /CLONE=IMAGE:4396576 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 BF983379 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005624 // membrane fraction // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored to membrane // inferred from electronic annotation /// 0031362 // anchored to external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200984_s_at X16447 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:X16447.1 /DEF=Human mRNA for CD59, an LY-6-like protein regulating complement membrane attack. /FEA=mRNA /PROD=precursor polypeptide (AA -25 to 103) /DB_XREF=gi:29805 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 X16447 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005624 // membrane fraction // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored to membrane // inferred from electronic annotation /// 0031362 // anchored to external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200985_s_at NM_000611 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000611.1 /DEF=Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNA. /FEA=mRNA /GEN=CD59 /PROD=CD59 antigen p18-20 (antigen identified bymonoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /DB_XREF=gi:10835164 /UG=Hs.119663 CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) /FL=gb:NM_000611.1 gb:M34671.1 NM_000611 CD59 molecule, complement regulatory protein CD59 966 NM_000611 /// NM_001127223 /// NM_001127225 /// NM_001127226 /// NM_001127227 /// NM_203329 /// NM_203330 /// NM_203331 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005624 // membrane fraction // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored to membrane // inferred from electronic annotation /// 0031362 // anchored to external side of plasma membrane // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 200986_at NM_000062 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000062.1 /DEF=Homo sapiens serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), mRNA. /FEA=mRNA /GEN=SERPING1 /PROD=complement component 1 inhibitor precursor /DB_XREF=gi:4557378 /UG=Hs.151242 serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1 /FL=gb:M13690.1 gb:M13656.1 gb:NM_000062.1 NM_000062 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 SERPING1 710 NM_000062 /// NM_001032295 0006955 // immune response // inferred from electronic annotation /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // inferred from electronic annotation /// 0008015 // blood circulation // traceable author statement /// 0045087 // innate immune response // inferred from electronic annotation 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // not recorded 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation 200987_x_at AA758755 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA758755 /FEA=EST /DB_XREF=gi:2806618 /DB_XREF=est:ah80c08.s1 /CLONE=1321934 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1 AA758755 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_005789 /// NM_176863 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008538 // proteasome activator activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200988_s_at NM_005789 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005789.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) (PSME3), mRNA. /FEA=mRNA /GEN=PSME3 /PROD=proteasome (prosome, macropain) activatorsubunit 3 (PA28 gamma; Ki) /DB_XREF=gi:5031996 /UG=Hs.152978 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) /FL=gb:NM_005789.1 gb:U11292.1 NM_005789 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) PSME3 10197 NM_005789 /// NM_176863 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008538 // proteasome activator activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 200989_at NM_001530 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001530.1 /DEF=Homo sapiens hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), mRNA. /FEA=mRNA /GEN=HIF1A /PROD=hypoxia-inducible factor 1, alpha subunit (basichelix-loop-helix transcription factor) /DB_XREF=gi:4504384 /UG=Hs.197540 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) /FL=gb:U29165.1 gb:AF304431.1 gb:NM_001530.1 gb:AF207601.1 gb:AF207602.1 gb:U22431.1 NM_001530 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) HIF1A 3091 NM_001530 /// NM_181054 0001525 // angiogenesis // inferred from electronic annotation /// 0001666 // response to hypoxia // inferred from direct assay /// 0001666 // response to hypoxia // inferred from mutant phenotype /// 0001755 // neural crest cell migration // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from electronic annotation /// 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0001938 // positive regulation of endothelial cell proliferation // inferred by curator /// 0001947 // heart looping // inferred from electronic annotation /// 0002248 // connective tissue replacement during inflammatory response // inferred from electronic annotation /// 0002248 // connective tissue replacement during inflammatory response // inferred from sequence or structural similarity /// 0006089 // lactate metabolic process // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // inferred from mutant phenotype /// 0010575 // positive regulation vascular endothelial growth factor production // inferred from direct assay /// 0010634 // positive regulation of epithelial cell migration // inferred from sequence or structural similarity /// 0014850 // response to muscle activity // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred from electronic annotation /// 0030949 // positive regulation of vascular endothelial growth factor receptor signaling pathway // inferred by curator /// 0032364 // oxygen homeostasis // inferred from direct assay /// 0032722 // positive regulation of chemokine production // traceable author statement /// 0032909 // regulation of transforming growth factor-beta2 production // inferred from mutant phenotype /// 0032963 // collagen metabolic process // inferred from electronic annotation /// 0032963 // collagen metabolic process // inferred from sequence or structural similarity /// 0035162 // embryonic hemopoiesis // inferred from electronic annotation /// 0042541 // hemoglobin biosynthetic process // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from electronic annotation /// 0042789 // mRNA transcription from RNA polymerase II promoter // inferred by curator /// 0042981 // regulation of apoptosis // inferred from electronic annotation /// 0043193 // positive regulation of gene-specific transcription // inferred from direct assay /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from electronic annotation /// 0043619 // regulation of transcription from RNA polymerase II promoter in response to oxidative stress // inferred from direct assay /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from direct assay /// 0045648 // positive regulation of erythrocyte differentiation // inferred from electronic annotation /// 0045648 // positive regulation of erythrocyte differentiation // inferred by curator /// 0045766 // positive regulation of angiogenesis // inferred by curator /// 0045821 // positive regulation of glycolysis // inferred by curator /// 0045926 // negative regulation of growth // inferred from electronic annotation /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046716 // muscle maintenance // inferred from electronic annotation /// 0046886 // positive regulation of hormone biosynthetic process // inferred from direct assay /// 0050790 // regulation of catalytic activity // inferred from electronic annotation /// 0051000 // positive regulation of nitric-oxide synthase activity // traceable author statement /// 0051216 // cartilage development // inferred from electronic annotation /// 0051541 // elastin metabolic process // inferred from electronic annotation /// 0051541 // elastin metabolic process // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0009434 // microtubule-based flagellum // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // traceable author statement /// 0003705 // RNA polymerase II transcription factor activity, enhancer binding // inferred from direct assay /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0035035 // histone acetyltransferase binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0046982 // protein heterodimerization activity // traceable author statement /// 0051879 // Hsp90 protein binding // inferred from direct assay 200990_at NM_005762 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005762.1 /DEF=Homo sapiens KRAB-associated protein 1 (TIF1B), mRNA. /FEA=mRNA /GEN=TIF1B /PROD=KRAB-associated protein 1 /DB_XREF=gi:5032178 /UG=Hs.228059 KRAB-associated protein 1 /FL=gb:BC004978.1 gb:U78773.1 gb:U95040.1 gb:NM_005762.1 NM_005762 tripartite motif-containing 28 TRIM28 10155 NM_005762 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0043193 // positive regulation of gene-specific transcription // inferred from sequence or structural similarity 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation 0003700 // transcription factor activity // inferred from sequence or structural similarity /// 0003700 // transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 200991_s_at NM_014748 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014748.1 /DEF=Homo sapiens KIAA0064 gene product (KIAA0064), mRNA. /FEA=mRNA /GEN=KIAA0064 /PROD=KIAA0064 gene product /DB_XREF=gi:7661889 /UG=Hs.278569 sorting nexin 17 /FL=gb:BC002524.1 gb:BC002610.1 gb:D31764.1 gb:NM_014748.1 NM_014748 sorting nexin 17 SNX17 9784 NM_014748 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006707 // cholesterol catabolic process // inferred by curator /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // non-traceable author statement /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016197 // endosome transport // non-traceable author statement /// 0030100 // regulation of endocytosis // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // inferred from electronic annotation /// 0004714 // transmembrane receptor protein tyrosine kinase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005003 // ephrin receptor activity // inferred from electronic annotation /// 0005102 // receptor binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay 200992_at AL137335 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL137335.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434A179 (from clone DKFZp434A179); partial cds. /FEA=mRNA /GEN=DKFZp434A179 /PROD=hypothetical protein /DB_XREF=gi:6807827 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AL137335 importin 7 IPO7 10527 NM_006391 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200993_at AA939270 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA939270 /FEA=EST /DB_XREF=gi:3099183 /DB_XREF=est:oq31b02.s1 /CLONE=IMAGE:1587915 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AA939270 importin 7 IPO7 10527 NM_006391 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200994_at BG291787 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG291787 /FEA=EST /DB_XREF=gi:13050002 /DB_XREF=est:602386007F1 /CLONE=IMAGE:4515240 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 BG291787 importin 7 IPO7 10527 NM_006391 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200995_at AI741392 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI741392 /FEA=EST /DB_XREF=gi:5109680 /DB_XREF=est:wg27b08.x1 /CLONE=IMAGE:2366295 /UG=Hs.5151 RAN binding protein 7 /FL=gb:AF098799.1 gb:NM_006391.1 AI741392 importin 7 IPO7 10527 NM_006391 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005083 // small GTPase regulator activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008536 // Ran GTPase binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0042393 // histone binding // inferred from electronic annotation 200996_at NM_005721 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005721.2 /DEF=Homo sapiens ARP3 (actin-related protein 3, yeast) homolog (ACTR3), mRNA. /FEA=mRNA /GEN=ACTR3 /PROD=ARP3 (actin-related protein 3, yeast) homolog /DB_XREF=gi:7262289 /UG=Hs.5321 ARP3 (actin-related protein 3, yeast) homolog /FL=gb:AF006083.1 gb:NM_005721.2 NM_005721 ARP3 actin-related protein 3 homolog (yeast) ACTR3 10096 NM_005721 0006928 // cell motion // traceable author statement /// 0030833 // regulation of actin filament polymerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005885 // Arp2/3 protein complex // traceable author statement /// 0015629 // actin cytoskeleton // traceable author statement /// 0030027 // lamellipodium // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 200997_at NM_002896 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002896.1 /DEF=Homo sapiens RNA binding motif protein 4 (RBM4), mRNA. /FEA=mRNA /GEN=RBM4 /PROD=RNA binding motif protein 4 /DB_XREF=gi:4506444 /UG=Hs.6106 RNA binding motif protein 4 /FL=gb:BC000307.1 gb:U89505.1 gb:NM_002896.1 NM_002896 RNA binding motif protein 4 RBM4 5936 NM_002896 0006260 // DNA replication // non-traceable author statement /// 0006281 // DNA repair // non-traceable author statement /// 0006310 // DNA recombination // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009725 // response to hormone stimulus // traceable author statement /// 0016575 // histone deacetylation // inferred from physical interaction /// 0030520 // estrogen receptor signaling pathway // non-traceable author statement /// 0042921 // glucocorticoid receptor signaling pathway // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0000119 // mediator complex // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from physical interaction /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016455 // RNA polymerase II transcription mediator activity // non-traceable author statement /// 0030374 // ligand-dependent nuclear receptor transcription coactivator activity // inferred from physical interaction /// 0030674 // protein binding, bridging // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 200998_s_at AW029619 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW029619 /FEA=EST /DB_XREF=gi:5888375 /DB_XREF=est:wx14e05.x1 /CLONE=IMAGE:2543648 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1 AW029619 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation 200999_s_at NM_006825 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006825.1 /DEF=Homo sapiens transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment (P63), mRNA. /FEA=mRNA /GEN=P63 /PROD=transmembrane protein (63kD), endoplasmicreticulumGolgi intermediate compartment /DB_XREF=gi:5803112 /UG=Hs.74368 transmembrane protein (63kD), endoplasmic reticulumGolgi intermediate compartment /FL=gb:NM_006825.1 NM_006825 cytoskeleton-associated protein 4 CKAP4 10970 NM_006825 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation 201000_at NM_001605 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001605.1 /DEF=Homo sapiens alanyl-tRNA synthetase (AARS), mRNA. /FEA=mRNA /GEN=AARS /PROD=alanyl-tRNA synthetase /DB_XREF=gi:4501840 /UG=Hs.75102 alanyl-tRNA synthetase /FL=gb:D32050.1 gb:NM_001605.1 NM_001605 alanyl-tRNA synthetase AARS 16 NM_001605 0006412 // translation // inferred from electronic annotation /// 0006419 // alanyl-tRNA aminoacylation // traceable author statement /// 0006419 // alanyl-tRNA aminoacylation // inferred from electronic annotation /// 0008033 // tRNA processing // traceable author statement /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004813 // alanine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation 201001_s_at BG164064 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG164064 /FEA=EST /DB_XREF=gi:12670767 /DB_XREF=est:602341091F1 /CLONE=IMAGE:4449022 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 BG164064 TMEM189-UBE2V1 readthrough transcript /// ubiquitin-conjugating enzyme E2 variant 1 TMEM189-UBE2V1 /// UBE2V1 387522 /// 7335 NM_001032288 /// NM_003349 /// NM_021988 /// NM_022442 /// NM_199144 /// NM_199203 0000209 // protein polyubiquitination // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // traceable author statement /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 201002_s_at U39361 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U39361.1 /DEF=Homo sapiens DNA-binding protein (CROC-1B) mRNA, complete cds. /FEA=mRNA /GEN=CROC-1B /PROD=DNA-binding protein /DB_XREF=gi:1066081 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 U39361 TMEM189-UBE2V1 readthrough transcript /// ubiquitin-conjugating enzyme E2 variant 1 TMEM189-UBE2V1 /// UBE2V1 387522 /// 7335 NM_001032288 /// NM_003349 /// NM_021988 /// NM_022442 /// NM_199144 /// NM_199203 0000209 // protein polyubiquitination // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // traceable author statement /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 201003_x_at NM_003349 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003349.2 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), transcript variant 2, mRNA. /FEA=mRNA /GEN=UBE2V1 /PROD=ubiquitin-conjugating enzyme E2 variant 1,isoform b /DB_XREF=gi:12025659 /UG=Hs.75875 ubiquitin-conjugating enzyme E2 variant 1 /FL=gb:U39361.1 gb:NM_003349.2 gb:BC000468.1 NM_003349 arginyl aminopeptidase (aminopeptidase B) /// transmembrane protein 189 /// TMEM189-UBE2V1 readthrough transcript /// ubiquitin-conjugating enzyme E2 variant 1 /// ubiquitin-conjugating enzyme E2 variant 1 pseudogene 2 RNPEP /// TMEM189 /// TMEM189-UBE2V1 /// UBE2V1 /// UBE2V1P2 387521 /// 387522 /// 6051 /// 730052 /// 7335 NM_001032288 /// NM_003349 /// NM_020216 /// NM_021988 /// NM_022442 /// NM_199129 /// NM_199144 /// NM_199203 /// XR_016022 /// XR_016054 /// XR_038933 0000209 // protein polyubiquitination // traceable author statement /// 0006282 // regulation of DNA repair // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006508 // proteolysis // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0019370 // leukotriene biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // non-traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031371 // ubiquitin conjugating enzyme complex // inferred from direct assay 0004177 // aminopeptidase activity // non-traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0004301 // epoxide hydrolase activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008235 // metalloexopeptidase activity // non-traceable author statement /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016563 // transcription activator activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201004_at NM_006280 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006280.1 /DEF=Homo sapiens signal sequence receptor, delta (translocon-associated protein delta) (SSR4), mRNA. /FEA=mRNA /GEN=SSR4 /PROD=signal sequence receptor, delta /DB_XREF=gi:5454089 /UG=Hs.102135 signal sequence receptor, delta (translocon-associated protein delta) /FL=gb:BC003371.1 gb:NM_006280.1 NM_006280 signal sequence receptor, delta (translocon-associated protein delta) SSR4 6748 NM_006280 0006886 // intracellular protein transport // non-traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005784 // translocon complex // non-traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201005_at NM_001769 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001769.1 /DEF=Homo sapiens CD9 antigen (p24) (CD9), mRNA. /FEA=mRNA /GEN=CD9 /PROD=CD9 antigen (p24) /DB_XREF=gi:4502692 /UG=Hs.1244 CD9 antigen (p24) /FL=gb:M38690.1 gb:NM_001769.1 gb:L34068.1 NM_001769 CD9 molecule CD9 928 NM_001769 0006928 // cell motion // inferred from direct assay /// 0007155 // cell adhesion // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007338 // single fertilization // inferred from electronic annotation /// 0007342 // fusion of sperm to egg plasma membrane // inferred from direct assay /// 0007342 // fusion of sperm to egg plasma membrane // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0030168 // platelet activation // non-traceable author statement /// 0030913 // paranodal junction assembly // inferred from electronic annotation /// 0030913 // paranodal junction assembly // inferred from sequence or structural similarity 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // non-traceable author statement /// 0005887 // integral to plasma membrane // non-traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031092 // platelet alpha granule membrane // not recorded 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201006_at NM_005809 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005809.1 /DEF=Homo sapiens peroxiredoxin 2 (PRDX2), mRNA. /FEA=mRNA /GEN=PRDX2 /PROD=peroxiredoxin 2 /DB_XREF=gi:5902725 /UG=Hs.146354 peroxiredoxin 2 /FL=gb:BC000452.1 gb:BC003022.1 gb:NM_005809.1 NM_005809 peroxiredoxin 2 PRDX2 7001 NM_005809 /// NM_181738 0006916 // anti-apoptosis // traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0006979 // response to oxidative stress // non-traceable author statement /// 0042098 // T cell proliferation // inferred from electronic annotation /// 0042743 // hydrogen peroxide metabolic process // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from mutant phenotype /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0048538 // thymus development // inferred from electronic annotation /// 0048872 // homeostasis of number of cells // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0008379 // thioredoxin peroxidase activity // inferred from direct assay /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016209 // antioxidant activity // inferred from direct assay /// 0016209 // antioxidant activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201007_at NM_000183 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000183.1 /DEF=Homo sapiens hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit (HADHB), mRNA. /FEA=mRNA /GEN=HADHB /PROD=hydroxyacyl-Coenzyme Adehydrogenase3-ketoacyl-Coenzyme Athiolaseenoyl-Coenzyme A hydratase (trifunctionalprotein), beta subunit /DB_XREF=gi:4504326 /UG=Hs.146812 hydroxyacyl-Coenzyme A dehydrogenase3-ketoacyl-Coenzyme A thiolaseenoyl-Coenzyme A hydratase (trifunctional protein), beta subunit /FL=gb:AF113209.1 gb:NM_000183.1 gb:D16481.1 NM_000183 hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit HADHB 3032 NM_000183 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // traceable author statement /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // traceable author statement /// 0003988 // acetyl-CoA C-acyltransferase activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // traceable author statement /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201008_s_at AA812232 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA812232 /FEA=EST /DB_XREF=gi:2881843 /DB_XREF=est:ob84h09.s1 /CLONE=IMAGE:1338113 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 AA812232 thioredoxin interacting protein TXNIP 10628 NM_006472 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201009_s_at AI439556 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI439556 /FEA=EST /DB_XREF=gi:4305149 /DB_XREF=est:tc90c12.x1 /CLONE=IMAGE:2073430 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 AI439556 thioredoxin interacting protein TXNIP 10628 NM_006472 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201010_s_at NM_006472 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006472.1 /DEF=Homo sapiens upregulated by 1,25-dihydroxyvitamin D-3 (VDUP1), mRNA. /FEA=mRNA /GEN=VDUP1 /PROD=upregulated by 1,25-dihydroxyvitamin D-3 /DB_XREF=gi:5454161 /UG=Hs.179526 upregulated by 1,25-dihydroxyvitamin D-3 /FL=gb:NM_006472.1 gb:S73591.1 NM_006472 thioredoxin interacting protein TXNIP 10628 NM_006472 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0030216 // keratinocyte differentiation // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201011_at NM_002950 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002950.1 /DEF=Homo sapiens ribophorin I (RPN1), mRNA. /FEA=mRNA /GEN=RPN1 /PROD=ribophorin I /DB_XREF=gi:4506674 /UG=Hs.2280 ribophorin I /FL=gb:NM_002950.1 NM_002950 ribophorin I RPN1 6184 NM_002950 0006464 // protein modification process // traceable author statement /// 0006486 // protein amino acid glycosylation // inferred from electronic annotation /// 0018279 // protein amino acid N-linked glycosylation via asparagine // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0008250 // oligosaccharyltransferase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030867 // rough endoplasmic reticulum membrane // inferred from sequence or structural similarity /// 0042470 // melanosome // inferred from electronic annotation 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // traceable author statement /// 0004579 // dolichyl-diphosphooligosaccharide-protein glycotransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation 201012_at NM_000700 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000700.1 /DEF=Homo sapiens annexin A1 (ANXA1), mRNA. /FEA=mRNA /GEN=ANXA1 /PROD=annexin I /DB_XREF=gi:4502100 /UG=Hs.78225 annexin A1 /FL=gb:BC001275.1 gb:NM_000700.1 NM_000700 annexin A1 ANXA1 301 NM_000700 0006629 // lipid metabolic process // traceable author statement /// 0006916 // anti-apoptosis // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0006954 // inflammatory response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030216 // keratinocyte differentiation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0050482 // arachidonic acid secretion // inferred from electronic annotation 0001533 // cornified envelope // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005929 // cilium // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005102 // receptor binding // traceable author statement /// 0005198 // structural molecule activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0019834 // phospholipase A2 inhibitor activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // inferred from direct assay 201013_s_at AA902652 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA902652 /FEA=EST /DB_XREF=gi:3037775 /DB_XREF=est:ok71a12.s1 /CLONE=IMAGE:1519390 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1 AA902652 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0009113 // purine base biosynthetic process // traceable author statement 0009320 // phosphoribosylaminoimidazole carboxylase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // inferred from electronic annotation /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // inferred from electronic annotation /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201014_s_at NM_006452 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006452.1 /DEF=Homo sapiens multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase (ADE2H1), mRNA. /FEA=mRNA /GEN=ADE2H1 /PROD=multifunctional polypeptide similar to SAICARsynthetase and AIR carboxylase /DB_XREF=gi:5453538 /UG=Hs.117950 multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase /FL=gb:NM_006452.1 NM_006452 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase PAICS 10606 NM_001079524 /// NM_001079525 /// NM_006452 0006164 // purine nucleotide biosynthetic process // inferred from electronic annotation /// 0006189 // 'de novo' IMP biosynthetic process // inferred from electronic annotation /// 0009113 // purine base biosynthetic process // traceable author statement 0009320 // phosphoribosylaminoimidazole carboxylase complex // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004638 // phosphoribosylaminoimidazole carboxylase activity // inferred from electronic annotation /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // inferred from electronic annotation /// 0004639 // phosphoribosylaminoimidazolesuccinocarboxamide synthase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201015_s_at NM_021991 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021991.1 /DEF=Homo sapiens junction plakoglobin (JUP), transcript variant 2, mRNA. /FEA=mRNA /GEN=JUP /PROD=junction plakoglobin, isoform 1 /DB_XREF=gi:12056467 /UG=Hs.2340 junction plakoglobin /FL=gb:NM_021991.1 gb:BC000441.1 NM_021991 junction plakoglobin JUP 3728 NM_002230 /// NM_021991 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0016337 // cell-cell adhesion // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0009898 // internal side of plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // traceable author statement 201016_at BE542684 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE542684 /FEA=EST /DB_XREF=gi:9771329 /DB_XREF=est:601067180F1 /CLONE=IMAGE:3453571 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BE542684 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 201017_at BG149698 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG149698 /FEA=EST /DB_XREF=gi:12661728 /DB_XREF=est:nad32e01.x1 /CLONE=IMAGE:3367368 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 BG149698 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 201018_at AL079283 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL079283.1 /DEF=Homo sapiens mRNA full length insert cDNA clone EUROIMAGE 39515. /FEA=mRNA /DB_XREF=gi:5102744 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 AL079283 eukaryotic translation initiation factor 1A, X-linked EIF1AX 1964 NM_001412 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 201019_s_at NM_001412 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001412.1 /DEF=Homo sapiens eukaryotic translation initiation factor 1A (EIF1A), mRNA. /FEA=mRNA /GEN=EIF1A /PROD=eukaryotic translation initiation factor 1A /DB_XREF=gi:4503498 /UG=Hs.4310 eukaryotic translation initiation factor 1A /FL=gb:BC000793.1 gb:L18960.1 gb:NM_001412.1 NM_001412 eukaryotic translation initiation factor 1A pseudogene 1 /// eukaryotic translation initiation factor 1A, X-linked EIF1AP1 /// EIF1AX 1964 /// 280661 NM_001412 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // traceable author statement /// 0006413 // translational initiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 201020_at NM_003405 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003405.1 /DEF=Homo sapiens tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH), mRNA. /FEA=mRNA /GEN=YWHAH /PROD=tyrosine 3-monooxygenasetryptophan5-monooxygenase activation protein, eta polypeptide /DB_XREF=gi:4507950 /UG=Hs.75544 tyrosine 3-monooxygenasetryptophan 5-monooxygenase activation protein, eta polypeptide /FL=gb:BC003047.1 gb:L20422.1 gb:NM_003405.1 NM_003405 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide YWHAH 7533 NM_003405 0006713 // glucocorticoid catabolic process // inferred from direct assay /// 0006886 // intracellular protein transport // inferred from sequence or structural similarity /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0042921 // glucocorticoid receptor signaling pathway // inferred from direct assay /// 0045664 // regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0048167 // regulation of synaptic plasticity // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from sequence or structural similarity /// 0050774 // negative regulation of dendrite morphogenesis // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // inferred from sequence or structural similarity /// 0004497 // monooxygenase activity // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016563 // transcription activator activity // inferred from direct assay /// 0019904 // protein domain specific binding // inferred from sequence or structural similarity /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0035259 // glucocorticoid receptor binding // inferred from physical interaction 201021_s_at BF697964 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF697964 /FEA=EST /DB_XREF=gi:11983372 /DB_XREF=est:602130050F1 /CLONE=IMAGE:4286556 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2 BF697964 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cell motion // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 201022_s_at NM_006870 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006870.2 /DEF=Homo sapiens destrin (actin depolymerizing factor) (ADF), mRNA. /FEA=mRNA /GEN=ADF /PROD=destrin (actin depolymerizing factor) /DB_XREF=gi:6466447 /UG=Hs.82306 destrin (actin depolymerizing factor) /FL=gb:NM_006870.2 NM_006870 destrin (actin depolymerizing factor) DSTN 11034 NM_001011546 /// NM_006870 0000910 // cytokinesis // inferred from electronic annotation /// 0006928 // cell motion // inferred from electronic annotation /// 0008154 // actin polymerization or depolymerization // traceable author statement /// 0030836 // positive regulation of actin filament depolymerization // inferred from electronic annotation /// 0051014 // actin filament severing // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0030864 // cortical actin cytoskeleton // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 201023_at NM_005642 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005642.1 /DEF=Homo sapiens TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD (TAF2F), mRNA. /FEA=mRNA /GEN=TAF2F /PROD=TATA box binding protein (TBP)-associatedfactor, RNA polymerase II, F, 55kD /DB_XREF=gi:5032148 /UG=Hs.155188 TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD /FL=gb:NM_005642.1 gb:U18062.1 NM_005642 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa TAF7 6879 NM_005642 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0030520 // estrogen receptor signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from direct assay /// 0005669 // transcription factor TFIID complex // inferred from electronic annotation /// 0005669 // transcription factor TFIID complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay 0003702 // RNA polymerase II transcription factor activity // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // traceable author statement /// 0016251 // general RNA polymerase II transcription factor activity // traceable author statement /// 0016251 // general RNA polymerase II transcription factor activity // inferred from electronic annotation 201024_x_at BG261322 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG261322 /FEA=EST /DB_XREF=gi:12771138 /DB_XREF=est:602373079F1 /CLONE=IMAGE:4484563 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 BG261322 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201025_at AB018284 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201026_at AB018284 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB018284.1 /DEF=Homo sapiens mRNA for KIAA0741 protein, complete cds. /FEA=mRNA /GEN=KIAA0741 /PROD=KIAA0741 protein /DB_XREF=gi:3882202 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 AB018284 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201027_s_at NM_015904 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015904.1 /DEF=Homo sapiens KIAA0741 gene product (IF2), mRNA. /FEA=mRNA /GEN=IF2 /PROD=translation initiation factor IF2 /DB_XREF=gi:7706231 /UG=Hs.158688 KIAA0741 gene product /FL=gb:AB018284.1 gb:AF078035.1 gb:NM_015904.1 NM_015904 eukaryotic translation initiation factor 5B EIF5B 9669 NM_015904 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // inferred from direct assay /// 0006446 // regulation of translational initiation // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // non-traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201028_s_at U82164 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U82164.1 /DEF=Human transmembrane protein CD99 type II mRNA, complete cds. /FEA=mRNA /GEN=CD99 /PROD=CD99 typeII /DB_XREF=gi:2149134 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1 U82164 CD99 molecule CD99 4267 NM_001122898 /// NM_002414 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201029_s_at NM_002414 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002414.1 /DEF=Homo sapiens antigen identified by monoclonal antibodies 12E7, F21 and O13 (MIC2), mRNA. /FEA=mRNA /GEN=MIC2 /PROD=antigen identified by monoclonal antibodies12E7, F21 and O13 /DB_XREF=gi:4505182 /UG=Hs.177543 antigen identified by monoclonal antibodies 12E7, F21 and O13 /FL=gb:BC002584.1 gb:BC003147.1 gb:M16279.1 gb:U82164.1 gb:NM_002414.1 NM_002414 CD99 molecule CD99 4267 NM_001122898 /// NM_002414 0007155 // cell adhesion // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201030_x_at NM_002300 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002300.1 /DEF=Homo sapiens lactate dehydrogenase B (LDHB), mRNA. /FEA=mRNA /GEN=LDHB /PROD=lactate dehydrogenase B /DB_XREF=gi:4557031 /UG=Hs.234489 lactate dehydrogenase B /FL=gb:BC002362.1 gb:NM_002300.1 NM_002300 lactate dehydrogenase B LDHB 3945 NM_002300 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006096 // glycolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019642 // anaerobic glycolysis // inferred from electronic annotation /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004459 // L-lactate dehydrogenase activity // traceable author statement /// 0004459 // L-lactate dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation 201031_s_at NM_005520 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005520.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H1 (H) (HNRPH1), mRNA. /FEA=mRNA /GEN=HNRPH1 /PROD=heterogeneous nuclear ribonucleoprotein H1 (H) /DB_XREF=gi:5031752 /UG=Hs.245710 heterogeneous nuclear ribonucleoprotein H1 (H) /FL=gb:BC001348.1 gb:L22009.1 gb:NM_005520.1 NM_005520 heterogeneous nuclear ribonucleoprotein H1 (H) HNRNPH1 3187 NM_005520 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008266 // poly(U) binding // traceable author statement 201032_at NM_006698 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006698.1 /DEF=Homo sapiens bladder cancer associated protein (BLCAP), mRNA. /FEA=mRNA /GEN=BLCAP /PROD=bladder cancer associated protein /DB_XREF=gi:5729737 /UG=Hs.5300 bladder cancer associated protein /FL=gb:AF053470.1 gb:NM_006698.1 NM_006698 bladder cancer associated protein BLCAP 10904 NM_006698 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201033_x_at NM_001002 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001002.1 /DEF=Homo sapiens ribosomal protein, large, P0 (RPLP0), mRNA. /FEA=mRNA /GEN=RPLP0 /PROD=ribosomal protein, large, P0 /DB_XREF=gi:4506666 /UG=Hs.73742 ribosomal protein, large, P0 /FL=gb:BC000345.1 gb:BC000752.1 gb:BC001127.1 gb:AF274958.1 gb:BC001834.1 gb:M17885.1 gb:NM_001002.1 NM_001002 ribosomal protein, large, P0 RPLP0 6175 NM_001002 /// NM_053275 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006414 // translational elongation // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201034_at BE545756 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE545756 /FEA=EST /DB_XREF=gi:9774401 /DB_XREF=est:601076920F1 /CLONE=IMAGE:3462940 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 BE545756 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201035_s_at BC000306 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000306.1 /DEF=Homo sapiens, L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, clone MGC:8392, mRNA, complete cds. /FEA=mRNA /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:12653080 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 BC000306 hydroxyacyl-Coenzyme A dehydrogenase HADH 3033 NM_005327 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // not recorded /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201036_s_at NM_005327 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005327.1 /DEF=Homo sapiens L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain (HADHSC), mRNA. /FEA=mRNA /GEN=HADHSC /PROD=L-3-hydroxyacyl-Coenzyme A dehydrogenase, shortchain /DB_XREF=gi:4885386 /UG=Hs.8110 L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain /FL=gb:BC000306.1 gb:NM_005327.1 NM_005327 hydroxyacyl-Coenzyme A dehydrogenase HADH 3033 NM_005327 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // not recorded /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // traceable author statement /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201037_at NM_002627 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002627.1 /DEF=Homo sapiens phosphofructokinase, platelet (PFKP), mRNA. /FEA=mRNA /GEN=PFKP /PROD=phosphofructokinase, platelet /DB_XREF=gi:11321600 /UG=Hs.99910 phosphofructokinase, platelet /FL=gb:NM_002627.1 gb:BC002536.1 gb:M64784.1 gb:D25328.1 NM_002627 phosphofructokinase, platelet PFKP 5214 NM_002627 0006096 // glycolysis // inferred from electronic annotation /// 0006096 // glycolysis // non-traceable author statement /// 0006096 // glycolysis // inferred from direct assay 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005945 // 6-phosphofructokinase complex // inferred from electronic annotation /// 0005945 // 6-phosphofructokinase complex // non-traceable author statement /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // traceable author statement /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201038_s_at T67821 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:T67821 /FEA=EST /DB_XREF=gi:678969 /DB_XREF=est:yc39d08.s1 /CLONE=IMAGE:83055 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 T67821 Cerebellar leucine rich acidic nuclear protein (LANP) ANP32A 8125 NM_006305 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007242 // intracellular signaling cascade // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201039_s_at BF572938 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF572938 /FEA=EST /DB_XREF=gi:11646661 /DB_XREF=est:602078949F2 /CLONE=IMAGE:4253100 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1 BF572938 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_005053 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006464 // protein modification process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201040_at NM_002070 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002070.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 (GNAI2), mRNA. /FEA=mRNA /GEN=GNAI2 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 2 /DB_XREF=gi:4504040 /UG=Hs.77269 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 /FL=gb:J03004.1 gb:NM_002070.1 NM_002070 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 GNAI2 2771 NM_002070 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0001973 // adenosine receptor signaling pathway // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // traceable author statement /// 0007193 // G-protein signaling, adenylate cyclase inhibiting pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // inferred from electronic annotation /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from electronic annotation /// 0007243 // protein kinase cascade // inferred from electronic annotation /// 0007584 // response to nutrient // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0050805 // negative regulation of synaptic transmission // inferred from electronic annotation /// 0051927 // negative regulation of calcium ion transport via voltage-gated calcium channel // inferred from electronic annotation 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation 201041_s_at NM_004417 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004417.2 /DEF=Homo sapiens dual specificity phosphatase 1 (DUSP1), mRNA. /FEA=mRNA /GEN=DUSP1 /PROD=dual specificity phosphatase 1 /DB_XREF=gi:7108342 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2 NM_004417 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 201042_at AL031651 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL031651 /DEF=Human DNA sequence from clone RP5-1054A22 on chromosome 20q11.22-12 Contains two isoforms of the gene for TGM2 (transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), ESTs, STSs, GSSs and a CpG island /FEA=mRNA_1 /DB_XREF=gi:6065866 /UG=Hs.8265 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) /FL=gb:M55153.1 gb:NM_004613.1 AL031651 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) TGM2 7052 NM_004613 /// NM_198951 0001974 // blood vessel remodeling // inferred from electronic annotation /// 0006917 // induction of apoptosis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from electronic annotation /// 0018153 // isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from sequence or structural similarity /// 0048661 // positive regulation of smooth muscle cell proliferation // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation /// 0051482 // elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from sequence or structural similarity /// 0003810 // protein-glutamine gamma-glutamyltransferase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201043_s_at NM_006305 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006305.1 /DEF=Homo sapiens putative human HLA class II associated protein I (PHAP1), mRNA. /FEA=mRNA /GEN=PHAP1 /PROD=putative human HLA class II associated proteinI /DB_XREF=gi:5453879 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 NM_006305 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A /// hypothetical protein LOC100128146 ANP32A /// LOC100128146 100128146 /// 8125 NM_006305 /// XM_001724880 /// XM_001725287 /// XM_001726740 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007242 // intracellular signaling cascade // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201044_x_at AA530892 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA530892 /FEA=EST /DB_XREF=gi:2273598 /DB_XREF=est:ni97d11.s1 /CLONE=IMAGE:984789 /UG=Hs.171695 dual specificity phosphatase 1 /FL=gb:NM_004417.2 AA530892 dual specificity phosphatase 1 DUSP1 1843 NM_004417 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0016311 // dephosphorylation // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017017 // MAP kinase tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation 201045_s_at BF513857 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF513857 /FEA=EST /DB_XREF=gi:11599036 /DB_XREF=est:UI-H-BW1-amz-e-01-0-UI.s1 /CLONE=IMAGE:3071689 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 BF513857 RAB6A, member RAS oncogene family RAB6A 5870 NM_002869 /// NM_198896 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0003924 // GTPase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201046_s_at NM_005053 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005053.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog A (RAD23A), mRNA. /FEA=mRNA /GEN=RAD23A /PROD=RAD23 (S. cerevisiae) homolog A /DB_XREF=gi:4826963 /UG=Hs.180455 RAD23 (S. cerevisiae) homolog A /FL=gb:NM_005053.1 gb:D21235.1 NM_005053 RAD23 homolog A (S. cerevisiae) RAD23A 5886 NM_005053 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006464 // protein modification process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201047_x_at BC003617 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003617.1 /DEF=Homo sapiens, RAB6, member RAS oncogene family, clone MGC:1654, mRNA, complete cds. /FEA=mRNA /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:13177663 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 BC003617 RAB6A, member RAS oncogene family RAB6A 5870 NM_002869 /// NM_198896 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0003924 // GTPase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201048_x_at NM_002869 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002869.1 /DEF=Homo sapiens RAB6, member RAS oncogene family (RAB6), mRNA. /FEA=mRNA /GEN=RAB6 /PROD=RAB6, member RAS oncogene family /DB_XREF=gi:4506372 /UG=Hs.5636 RAB6A, member RAS oncogene family /FL=gb:BC003617.1 gb:NM_002869.1 gb:AF130986.1 gb:AF130122.1 gb:M28212.1 gb:AF119836.1 gb:AF198616.1 NM_002869 RAB6A, member RAS oncogene family RAB6A 5870 NM_002869 /// NM_198896 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0042493 // response to drug // inferred from direct assay 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred by curator /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0003924 // GTPase activity // inferred from direct assay /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201049_s_at NM_022551 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_022551.1 /DEF=Homo sapiens ribosomal protein S18 (RPS18), mRNA. /FEA=mRNA /GEN=RPS18 /PROD=ribosomal protein S18 /DB_XREF=gi:11968181 /UG=Hs.275865 ribosomal protein S18 /FL=gb:NM_022551.1 NM_022551 hypothetical protein LOC100130553 /// ribosomal protein S18 LOC100130553 /// RPS18 100130553 /// 6222 NM_022551 /// XM_001713658 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0005840 // ribosome // non-traceable author statement /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0004886 // retinoid-X receptor activity // inferred from electronic annotation /// 0019843 // rRNA binding // inferred from electronic annotation /// 0030375 // thyroid hormone receptor coactivator activity // inferred from electronic annotation /// 0042809 // vitamin D receptor binding // inferred from electronic annotation /// 0042974 // retinoic acid receptor binding // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201050_at NM_012268 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012268.1 /DEF=Homo sapiens similar to vaccinia virus HindIII K4L ORF (HU-K4), mRNA. /FEA=mRNA /GEN=HU-K4 /PROD=similar to vaccinia virus HindIII K4L ORF /DB_XREF=gi:7110640 /UG=Hs.74573 similar to vaccinia virus HindIII K4L ORF /FL=gb:BC000553.1 gb:U60644.1 gb:NM_012268.1 NM_012268 phospholipase D family, member 3 PLD3 23646 NM_001031696 /// NM_012268 0008152 // metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004630 // phospholipase D activity // traceable author statement /// 0004630 // phospholipase D activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201051_at BE560202 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE560202 /FEA=EST /DB_XREF=gi:9803834 /DB_XREF=est:601347428F1 /CLONE=IMAGE:3688350 /UG=Hs.285013 putative human HLA class II associated protein I /FL=gb:U60823.1 gb:U73477.1 gb:AF025684.1 gb:NM_006305.1 BE560202 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A ANP32A 8125 NM_006305 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // non-traceable author statement /// 0007242 // intracellular signaling cascade // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201052_s_at BG029917 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG029917 /FEA=EST /DB_XREF=gi:12419014 /DB_XREF=est:602297261F1 /CLONE=IMAGE:4391534 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1 BG029917 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) PSMF1 9491 NM_006814 /// NM_178578 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // non-traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008539 // proteasome inhibitor activity // non-traceable author statement 201053_s_at NM_006814 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006814.1 /DEF=Homo sapiens proteasome (prosome, macropain) inhibitor subunit 1 (PI31) (PSMF1), mRNA. /FEA=mRNA /GEN=PSMF1 /PROD=proteasome inhibitor /DB_XREF=gi:5803122 /UG=Hs.75925 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) /FL=gb:D88378.1 gb:NM_006814.1 NM_006814 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) PSMF1 9491 NM_006814 /// NM_178578 0006511 // ubiquitin-dependent protein catabolic process // non-traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // non-traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008539 // proteasome inhibitor activity // non-traceable author statement 201054_at BE966599 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE966599 /FEA=EST /DB_XREF=gi:11772191 /DB_XREF=est:601660283R1 /CLONE=IMAGE:3906044 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1 BE966599 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201055_s_at NM_006805 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006805.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein A0 (HNRPA0), mRNA. /FEA=mRNA /GEN=HNRPA0 /PROD=heterogeneous nuclear ribonucleoprotein A0 /DB_XREF=gi:5803035 /UG=Hs.77492 heterogeneous nuclear ribonucleoprotein A0 /FL=gb:BC001008.1 gb:NM_006805.1 gb:U23803.1 NM_006805 heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 10949 NM_006805 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201056_at N53479 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N53479 /FEA=EST /DB_XREF=gi:1194645 /DB_XREF=est:yv42c11.s1 /CLONE=IMAGE:245396 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1 N53479 golgin B1, golgi integral membrane protein GOLGB1 2804 NM_004487 0007030 // Golgi organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201057_s_at NM_004487 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004487.1 /DEF=Homo sapiens golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 (GOLGB1), mRNA. /FEA=mRNA /GEN=GOLGB1 /PROD=golgi autoantigen, golgin subfamily b,macrogolgin (with transmembrane signal), 1 /DB_XREF=gi:4758453 /UG=Hs.7844 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 /FL=gb:NM_004487.1 NM_004487 golgin B1, golgi integral membrane protein GOLGB1 2804 NM_004487 0007030 // Golgi organization // traceable author statement 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005793 // ER-Golgi intermediate compartment // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005795 // Golgi stack // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201058_s_at NM_006097 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006097.1 /DEF=Homo sapiens myosin regulatory light chain 2, smooth muscle isoform (MYRL2), mRNA. /FEA=mRNA /GEN=MYRL2 /PROD=myosin regulatory light chain 2, smooth muscleisoform /DB_XREF=gi:5174602 /UG=Hs.9615 myosin regulatory light chain 2, smooth muscle isoform /FL=gb:J02854.1 gb:NM_006097.1 NM_006097 myosin, light chain 9, regulatory MYL9 10398 NM_006097 /// NM_181526 0006937 // regulation of muscle contraction // traceable author statement 0005859 // muscle myosin complex // traceable author statement /// 0016459 // myosin complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement 201059_at NM_005231 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005231.1 /DEF=Homo sapiens ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) (EMS1), mRNA. /FEA=mRNA /GEN=EMS1 /PROD=cortactin /DB_XREF=gi:4885204 /UG=Hs.119257 ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p8085 src substrate) /FL=gb:M98343.1 gb:NM_005231.1 NM_005231 cortactin CTTN 2017 NM_005231 /// NM_138565 0006898 // receptor-mediated endocytosis // inferred from electronic annotation 0001726 // ruffle // inferred from sequence or structural similarity /// 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0005938 // cell cortex // inferred from sequence or structural similarity /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction 201060_x_at AI537887 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI537887 /FEA=EST /DB_XREF=gi:4452022 /DB_XREF=est:tp32g06.x1 /CLONE=IMAGE:2189530 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 AI537887 stomatin STOM 2040 NM_004099 /// NM_198194 0051260 // protein homooligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201061_s_at M81635 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 M81635 stomatin STOM 2040 NM_004099 /// NM_198194 0051260 // protein homooligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201062_at M81635 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M81635.1 /DEF=Homo sapiens erythrocyte membrane protein mRNA, complete cds. /FEA=mRNA /GEN=stomatin peptide /PROD=stomatin peptide /DB_XREF=gi:181183 /UG=Hs.160483 erythrocyte membrane protein band 7.2 (stomatin) /FL=gb:M81635.1 gb:NM_004099.1 M81635 stomatin STOM 2040 NM_004099 /// NM_198194 0051260 // protein homooligomerization // inferred from direct assay 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay 0005515 // protein binding // inferred from physical interaction 201063_at NM_002901 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002901.1 /DEF=Homo sapiens reticulocalbin 1, EF-hand calcium binding domain (RCN1), mRNA. /FEA=mRNA /GEN=RCN1 /PROD=reticulocalbin 1 precursor /DB_XREF=gi:4506454 /UG=Hs.167791 reticulocalbin 1, EF-hand calcium binding domain /FL=gb:D42073.1 gb:NM_002901.1 NM_002901 reticulocalbin 1, EF-hand calcium binding domain RCN1 5954 NM_002901 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation 201064_s_at NM_003819 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003819.2 /DEF=Homo sapiens poly(A)-binding protein, cytoplasmic 4 (inducible form) (PABPC4), mRNA. /FEA=mRNA /GEN=PABPC4 /PROD=poly(A)-binding protein, cytoplasmic 4(inducible form) /DB_XREF=gi:6552335 /UG=Hs.169900 poly(A)-binding protein, cytoplasmic 4 (inducible form) /FL=gb:NM_003819.2 NM_003819 poly(A) binding protein, cytoplasmic 4 (inducible form) PABPC4 8761 NM_001135653 /// NM_001135654 /// NM_003819 0006396 // RNA processing // traceable author statement /// 0006401 // RNA catabolic process // traceable author statement /// 0006412 // translation // traceable author statement /// 0007596 // blood coagulation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // inferred from direct assay /// 0008143 // poly(A) binding // traceable author statement /// 0008266 // poly(U) binding // inferred from direct assay /// 0017130 // poly(rC) binding // inferred from direct assay 201065_s_at NM_001518 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001518.1 /DEF=Homo sapiens general transcription factor II, i (GTF2I), mRNA. /FEA=mRNA /GEN=GTF2I /PROD=general transcription factor II, i /DB_XREF=gi:4504202 /UG=Hs.278589 general transcription factor II, i /FL=gb:U77948.1 gb:AF015553.1 gb:AF038969.1 gb:NM_001518.1 NM_001518 general transcription factor II, i /// general transcription factor II, i, pseudogene 1 /// general transcription factor II, i, pseudogene GTF2I /// GTF2IP1 /// LOC100093631 100093631 /// 2969 /// 2970 NM_001518 /// NM_032999 /// NM_033000 /// NM_033001 /// NR_002206 /// NR_003580 /// XM_001133646 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0016251 // general RNA polymerase II transcription factor activity // traceable author statement 201066_at NM_001916 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001916.1 /DEF=Homo sapiens cytochrome c-1 (CYC1), mRNA. /FEA=mRNA /GEN=CYC1 /PROD=cytochrome c-1 /DB_XREF=gi:4503184 /UG=Hs.289271 cytochrome c-1 /FL=gb:BC001006.1 gb:NM_001916.1 NM_001916 cytochrome c-1 CYC1 1537 NM_001916 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0045155 // electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201067_at BF215487 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF215487 /FEA=EST /DB_XREF=gi:11109176 /DB_XREF=est:601881048F1 /CLONE=IMAGE:4093691 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1 BF215487 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PSMC2 5701 NM_002803 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201068_s_at NM_002803 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002803.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 2 (PSMC2), mRNA. /FEA=mRNA /GEN=PSMC2 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 2 /DB_XREF=gi:4506208 /UG=Hs.61153 proteasome (prosome, macropain) 26S subunit, ATPase, 2 /FL=gb:BC002589.1 gb:D11094.1 gb:NM_002803.1 NM_002803 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PSMC2 5701 NM_002803 0006511 // ubiquitin-dependent protein catabolic process // inferred from direct assay /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201069_at NM_004530 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004530.1 /DEF=Homo sapiens matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) (MMP2), mRNA. /FEA=mRNA /GEN=MMP2 /PROD=matrix metalloproteinase 2 preproprotein /DB_XREF=gi:11342665 /UG=Hs.111301 matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase) /FL=gb:NM_004530.1 gb:BC002576.1 NM_004530 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) MMP2 4313 NM_001127891 /// NM_004530 0001666 // response to hypoxia // inferred from electronic annotation /// 0001955 // blood vessel maturation // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030574 // collagen catabolic process // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0030017 // sarcomere // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0004222 // metalloendopeptidase activity // traceable author statement /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201070_x_at AI739389 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI739389 /FEA=EST /DB_XREF=gi:5101370 /DB_XREF=est:wi29f09.x1 /CLONE=IMAGE:2391689 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1 AI739389 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // non-traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0031202 // RNA splicing factor activity, transesterification mechanism // non-traceable author statement 201071_x_at NM_012433 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012433.1 /DEF=Homo sapiens splicing factor 3b, subunit 1, 155kD (SF3B1), mRNA. /FEA=mRNA /GEN=SF3B1 /PROD=splicing factor 3b, subunit 1, 155kD /DB_XREF=gi:6912653 /UG=Hs.13453 splicing factor 3b, subunit 1, 155kD /FL=gb:AF054284.1 gb:NM_012433.1 NM_012433 splicing factor 3b, subunit 1, 155kDa SF3B1 23451 NM_001005526 /// NM_012433 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // non-traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // non-traceable author statement /// 0005681 // spliceosome // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0031202 // RNA splicing factor activity, transesterification mechanism // non-traceable author statement 201072_s_at AW152160 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW152160 /FEA=EST /DB_XREF=gi:6200058 /DB_XREF=est:xf75e01.x1 /CLONE=IMAGE:2623896 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AW152160 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 201073_s_at AL040633 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL040633 /FEA=EST /DB_XREF=gi:5409580 /DB_XREF=est:DKFZp434M2414_s1 /CLONE=DKFZp434M2414 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AL040633 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 201074_at AA593983 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA593983 /FEA=EST /DB_XREF=gi:2409333 /DB_XREF=est:nn16d01.s1 /CLONE=IMAGE:1084033 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 AA593983 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 201075_s_at NM_003074 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003074.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1), mRNA. /FEA=mRNA /GEN=SMARCC1 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 1 /DB_XREF=gi:4507078 /UG=Hs.172280 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 /FL=gb:U66615.1 gb:NM_003074.1 NM_003074 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 SMARCC1 6599 NM_003074 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction 201076_at NM_005008 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005008.1 /DEF=Homo sapiens non-histone chromosome protein 2 (S. cerevisiae)-like 1 (NHP2L1), mRNA. /FEA=mRNA /GEN=NHP2L1 /PROD=non-histone chromosome protein 2 (S.cerevisiae)-like 1 /DB_XREF=gi:4826859 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1 NM_005008 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) NHP2L1 4809 NM_001003796 /// NM_005008 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201077_s_at AF155235 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF155235.1 /DEF=Homo sapiens 15.5 kD RNA binding protein mRNA, complete cds. /FEA=mRNA /PROD=15.5 kD RNA binding protein /DB_XREF=gi:6318598 /UG=Hs.182255 non-histone chromosome protein 2 (S. cerevisiae)-like 1 /FL=gb:BC005358.1 gb:D50420.1 gb:AF091076.1 gb:NM_005008.1 gb:AF155235.1 AF155235 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) NHP2L1 4809 NM_001003796 /// NM_005008 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201078_at NM_004800 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004800.1 /DEF=Homo sapiens transmembrane 9 superfamily member 2 (TM9SF2), mRNA. /FEA=mRNA /GEN=TM9SF2 /PROD=transmembrane 9 superfamily member 2 /DB_XREF=gi:4758873 /UG=Hs.28757 transmembrane 9 superfamily member 2 /FL=gb:U81006.1 gb:NM_004800.1 NM_004800 transmembrane 9 superfamily member 2 TM9SF2 9375 NM_004800 0006810 // transport // traceable author statement 0005768 // endosome // traceable author statement /// 0005768 // endosome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201079_at NM_004710 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004710.1 /DEF=Homo sapiens synaptogyrin 2 (SYNGR2), mRNA. /FEA=mRNA /GEN=SYNGR2 /PROD=synaptogyrin 2 /DB_XREF=gi:4759201 /UG=Hs.5097 synaptogyrin 2 /FL=gb:BC000407.1 gb:NM_004710.1 NM_004710 synaptogyrin 2 SYNGR2 9144 NM_004710 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201080_at BF338509 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF338509 /FEA=EST /DB_XREF=gi:11284912 /DB_XREF=est:602034176F2 /CLONE=IMAGE:4182187 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1 BF338509 phosphatidylinositol-5-phosphate 4-kinase, type II, beta PIP4K2B 8396 NM_003559 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201081_s_at NM_003559 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003559.1 /DEF=Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type II, beta (PIP5K2B), mRNA. /FEA=mRNA /GEN=PIP5K2B /PROD=phosphatidylinositol-4-phosphate 5-kinase, typeII, beta /DB_XREF=gi:4505818 /UG=Hs.6335 phosphatidylinositol-4-phosphate 5-kinase, type II, beta /FL=gb:U85245.1 gb:NM_003559.1 NM_003559 phosphatidylinositol-5-phosphate 4-kinase, type II, beta PIP4K2B 8396 NM_003559 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0046488 // phosphatidylinositol metabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016307 // phosphatidylinositol phosphate kinase activity // inferred from electronic annotation /// 0016308 // 1-phosphatidylinositol-4-phosphate 5-kinase activity // inferred from direct assay /// 0016309 // 1-phosphatidylinositol-5-phosphate 4-kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201082_s_at NM_004082 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004082.2 /DEF=Homo sapiens dynactin 1 (p150, Glued (Drosophila) homolog) (DCTN1), transcript variant 1, mRNA. /FEA=mRNA /GEN=DCTN1 /PROD=dynactin 1, isoform 1 /DB_XREF=gi:13259509 /UG=Hs.74617 dynactin 1 (p150, Glued (Drosophila) homolog) /FL=gb:NM_023019.1 gb:NM_004082.2 NM_004082 dynactin 1 (p150, glued homolog, Drosophila) DCTN1 1639 NM_001135040 /// NM_001135041 /// NM_004082 /// NM_023019 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation /// 0006820 // anion transport // inferred from electronic annotation /// 0007067 // mitosis // non-traceable author statement /// 0007399 // nervous system development // non-traceable author statement 0000922 // spindle pole // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030286 // dynein complex // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005215 // transporter activity // inferred from electronic annotation /// 0005452 // inorganic anion exchanger activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008509 // anion transmembrane transporter activity // inferred from electronic annotation /// 0015380 // anion exchanger activity // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation 201083_s_at AA740754 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA740754 /FEA=EST /DB_XREF=gi:2779346 /DB_XREF=est:nz03b05.s1 /CLONE=IMAGE:1286673 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 AA740754 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // traceable author statement /// 0016564 // transcription repressor activity // inferred from direct assay 201084_s_at NM_014739 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014739.1 /DEF=Homo sapiens KIAA0164 gene product (KIAA0164), mRNA. /FEA=mRNA /GEN=KIAA0164 /PROD=KIAA0164 gene product /DB_XREF=gi:7661957 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 NM_014739 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // traceable author statement /// 0016564 // transcription repressor activity // inferred from direct assay 201085_s_at AA664291 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA664291 /FEA=EST /DB_XREF=gi:2618282 /DB_XREF=est:ac08d09.s1 /CLONE=IMAGE:855857 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1 AA664291 SON DNA binding protein SON 6651 NM_032195 /// NM_138927 0006916 // anti-apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201086_x_at NM_003103 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003103.1 /DEF=Homo sapiens SON DNA binding protein (SON), mRNA. /FEA=mRNA /GEN=SON /PROD=SON DNA binding protein /DB_XREF=gi:4507152 /UG=Hs.92909 SON DNA binding protein /FL=gb:NM_003103.1 NM_003103 SON DNA binding protein SON 6651 NM_032195 /// NM_138927 0006916 // anti-apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // traceable author statement /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201087_at NM_002859 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002859.1 /DEF=Homo sapiens paxillin (PXN), mRNA. /FEA=mRNA /GEN=PXN /PROD=paxillin /DB_XREF=gi:4506344 /UG=Hs.102497 paxillin /FL=gb:NM_002859.1 gb:U14588.1 NM_002859 paxillin PXN 5829 NM_001080855 /// NM_002859 /// NM_025157 0007155 // cell adhesion // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007172 // signal complex assembly // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from expression pattern 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005875 // microtubule associated complex // traceable author statement /// 0005886 // plasma membrane // not recorded /// 0005925 // focal adhesion // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017166 // vinculin binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201088_at NM_002266 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002266.1 /DEF=Homo sapiens karyopherin alpha 2 (RAG cohort 1, importin alpha 1) (KPNA2), mRNA. /FEA=mRNA /GEN=KPNA2 /PROD=karyopherin alpha 2 /DB_XREF=gi:4504896 /UG=Hs.159557 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) /FL=gb:NM_002266.1 gb:U09559.1 gb:U28386.1 NM_002266 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) /// karyopherin alpha-2 subunit like KPNA2 /// LOC728860 3838 /// 728860 NM_002266 /// XM_001722955 /// XM_001722957 0000018 // regulation of DNA recombination // traceable author statement /// 0000072 // M phase specific microtubule process // traceable author statement /// 0000085 // G2 phase of mitotic cell cycle // traceable author statement /// 0006259 // DNA metabolic process // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006607 // NLS-bearing substrate import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0008139 // nuclear localization sequence binding // traceable author statement /// 0008565 // protein transporter activity // inferred from electronic annotation 201089_at NM_001693 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001693.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 (ATP6B2), mRNA. /FEA=mRNA /GEN=ATP6B2 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump), beta polypeptide, 5658kD, isoform 2 /DB_XREF=gi:4502310 /UG=Hs.1697 ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 5658kD, isoform 2 /FL=gb:BC003100.1 gb:NM_001693.1 gb:L35249.1 NM_001693 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 ATP6V1B2 526 NM_001693 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // inferred from electronic annotation /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201090_x_at NM_006082 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006082.1 /DEF=Homo sapiens tubulin, alpha, ubiquitous (K-ALPHA-1), mRNA. /FEA=mRNA /GEN=K-ALPHA-1 /PROD=tubulin, alpha, ubiquitous /DB_XREF=gi:5174476 /UG=Hs.278242 tubulin, alpha, ubiquitous /FL=gb:BC000696.1 gb:BC001128.1 gb:BC001209.1 gb:K00558.1 gb:AF081484.1 gb:NM_006082.1 NM_006082 tubulin, alpha 1b TUBA1B 10376 NM_006082 0007017 // microtubule-based process // inferred from electronic annotation /// 0007018 // microtubule-based movement // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0005874 // microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 201091_s_at BE748755 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE748755 /FEA=EST /DB_XREF=gi:10162747 /DB_XREF=est:601571933T1 /CLONE=IMAGE:3838737 /UG=Hs.278554 heterochromatin-like protein 1 /FL=gb:AF136630.1 gb:NM_016587.1 BE748755 chromobox homolog 3 (HP1 gamma homolog, Drosophila) /// similar to chromobox homolog 3 CBX3 /// LOC653972 11335 /// 653972 NM_007276 /// NM_016587 /// XM_938779 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0016568 // chromatin modification // inferred from electronic annotation 0000779 // condensed chromosome, centromeric region // inferred from sequence or structural similarity /// 0000785 // chromatin // inferred from direct assay /// 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // non-traceable author statement /// 0005701 // polytene chromosome chromocenter // inferred from sequence or structural similarity /// 0005719 // nuclear euchromatin // inferred from direct assay /// 0005720 // nuclear heterochromatin // inferred from direct assay /// 0005819 // spindle // inferred from direct assay /// 0031618 // nuclear centromeric heterochromatin // inferred from sequence or structural similarity 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016565 // general transcriptional repressor activity // inferred from mutant phenotype /// 0019904 // protein domain specific binding // inferred from physical interaction 201092_at NM_002893 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002893.2 /DEF=Homo sapiens retinoblastoma-binding protein 7 (RBBP7), mRNA. /FEA=mRNA /GEN=RBBP7 /PROD=retinoblastoma-binding protein 7 /DB_XREF=gi:13259504 /UG=Hs.31314 retinoblastoma-binding protein 7 /FL=gb:U35143.1 gb:NM_002893.2 NM_002893 retinoblastoma binding protein 7 RBBP7 5931 NM_002893 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016581 // NuRD complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from electronic annotation 201093_x_at NM_004168 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004168.1 /DEF=Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=SDHA /PROD=succinate dehydrogenase complex, subunit A,flavoprotein precursor /DB_XREF=gi:4759079 /UG=Hs.469 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) /FL=gb:BC001380.1 gb:L21936.1 gb:NM_004168.1 gb:D30648.1 NM_004168 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) SDHA 6389 NM_004168 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // traceable author statement /// 0006105 // succinate metabolic process // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0007399 // nervous system development // inferred from mutant phenotype /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from direct assay /// 0055114 // oxidation reduction // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // not recorded /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005749 // mitochondrial respiratory chain complex II // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000104 // succinate dehydrogenase activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0008177 // succinate dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016627 // oxidoreductase activity, acting on the CH-CH group of donors // inferred from electronic annotation /// 0050660 // FAD binding // inferred from electronic annotation 201094_at NM_001032 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001032.1 /DEF=Homo sapiens ribosomal protein S29 (RPS29), mRNA. /FEA=mRNA /GEN=RPS29 /PROD=ribosomal protein S29 /DB_XREF=gi:4506716 /UG=Hs.539 ribosomal protein S29 /FL=gb:L31610.1 gb:NM_001032.1 gb:U14973.1 NM_001032 ribosomal protein S29 RPS29 6235 NM_001030001 /// NM_001032 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201095_at NM_004394 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004394.1 /DEF=Homo sapiens death-associated protein (DAP), mRNA. /FEA=mRNA /GEN=DAP /PROD=death-associated protein /DB_XREF=gi:4758119 /UG=Hs.75189 death-associated protein /FL=gb:BC002726.1 gb:NM_004394.1 NM_004394 death-associated protein DAP 1611 NM_004394 0006915 // apoptosis // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // traceable author statement 201096_s_at AL537042 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL537042 /FEA=EST /DB_XREF=gi:12800535 /DB_XREF=est:AL537042 /CLONE=CS0DF017YF17 (5 prime) /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2 AL537042 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201097_s_at NM_001660 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001660.2 /DEF=Homo sapiens ADP-ribosylation factor 4 (ARF4), mRNA. /FEA=mRNA /GEN=ARF4 /PROD=ADP-ribosylation factor 4 /DB_XREF=gi:6995998 /UG=Hs.75290 ADP-ribosylation factor 4 /FL=gb:BC003364.1 gb:M36341.1 gb:NM_001660.2 NM_001660 ADP-ribosylation factor 4 ARF4 378 NM_001660 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201098_at NM_004766 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004766.1 /DEF=Homo sapiens coatomer protein complex, subunit beta 2 (beta prime) (COPB2), mRNA. /FEA=mRNA /GEN=COPB2 /PROD=coatomer protein complex, subunit beta 2 (betaprime) /DB_XREF=gi:4758031 /UG=Hs.75724 coatomer protein complex, subunit beta 2 (beta prime) /FL=gb:BC000326.1 gb:NM_004766.1 NM_004766 coatomer protein complex, subunit beta 2 (beta prime) COPB2 9276 NM_004766 /// NR_023350 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // traceable author statement /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from direct assay /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201099_at AA824386 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA824386 /FEA=EST /DB_XREF=gi:2896270 /DB_XREF=est:aj29c05.s1 /CLONE=1391720 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2 AA824386 ubiquitin specific peptidase 9, X-linked USP9X 8239 NM_001039590 /// NM_001039591 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 201100_s_at NM_004652 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004652.2 /DEF=Homo sapiens ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) (USP9X), transcript variant 1, mRNA. /FEA=mRNA /GEN=USP9X /PROD=Drosophila fat facets related, X-linked, isoform1 /DB_XREF=gi:11641424 /UG=Hs.77578 ubiquitin specific protease 9, X chromosome (Drosophila fat facets related) /FL=gb:NM_004652.2 NM_004652 ubiquitin specific peptidase 9, X-linked USP9X 8239 NM_001039590 /// NM_001039591 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007292 // female gamete generation // traceable author statement 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 201101_s_at BE963370 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE963370 /FEA=EST /DB_XREF=gi:11766788 /DB_XREF=est:601657132R1 /CLONE=IMAGE:3866335 /UG=Hs.80338 KIAA0164 gene product /FL=gb:D79986.1 gb:NM_014739.1 BE963370 BCL2-associated transcription factor 1 BCLAF1 9774 NM_001077440 /// NM_001077441 /// NM_014739 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // traceable author statement /// 0016564 // transcription repressor activity // inferred from direct assay 201102_s_at NM_002626 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002626.1 /DEF=Homo sapiens phosphofructokinase, liver (PFKL), mRNA. /FEA=mRNA /GEN=PFKL /PROD=phosphofructokinase, liver /DB_XREF=gi:4505746 /UG=Hs.155455 phosphofructokinase, liver /FL=gb:BC004920.1 gb:X15573.1 gb:NM_002626.1 NM_002626 phosphofructokinase, liver PFKL 5211 NM_001002021 /// NM_002626 /// NR_024108 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006002 // fructose 6-phosphate metabolic process // inferred from direct assay /// 0006002 // fructose 6-phosphate metabolic process // inferred from mutant phenotype /// 0006096 // glycolysis // inferred from direct assay /// 0006096 // glycolysis // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0005945 // 6-phosphofructokinase complex // inferred from direct assay /// 0005945 // 6-phosphofructokinase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003872 // 6-phosphofructokinase activity // inferred from direct assay /// 0003872 // 6-phosphofructokinase activity // inferred from mutant phenotype /// 0003872 // 6-phosphofructokinase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0070061 // fructose binding // inferred from direct assay 201103_x_at BE299495 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE299495 /FEA=EST /DB_XREF=gi:9183243 /DB_XREF=est:600944774T1 /CLONE=IMAGE:2960610 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1 BE299495 KIAA1245 /// neuroblastoma breakpoint family, member 1 /// neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 12 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 16 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9 /// hypothetical protein LOC200030 KIAA1245 /// NBPF1 /// NBPF10 /// NBPF11 /// NBPF12 /// NBPF14 /// NBPF15 /// NBPF16 /// NBPF20 /// NBPF8 /// NBPF9 /// RP11-94I2.2 100132406 /// 149013 /// 200030 /// 25832 /// 284565 /// 400818 /// 440670 /// 440675 /// 55672 /// 728841 /// 728912 /// 728936 NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_015383 /// NM_017940 /// NM_173638 /// NM_183372 /// XM_001715810 /// XM_001717398 /// XM_001717802 /// XM_001721345 /// XM_001721349 /// XM_001722184 /// XM_001723523 /// XM_001726946 0005737 // cytoplasm // inferred from electronic annotation 201104_x_at NM_015383 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015383.1 /DEF=Homo sapiens hypothetical protein (DJ328E19.C1.1), mRNA. /FEA=mRNA /GEN=DJ328E19.C1.1 /PROD=hypothetical protein /DB_XREF=gi:7657016 /UG=Hs.218329 hypothetical protein /FL=gb:NM_015383.1 NM_015383 KIAA1245 /// neuroblastoma breakpoint family, member 1 /// neuroblastoma breakpoint family, member 10 /// neuroblastoma breakpoint family, member 11 /// neuroblastoma breakpoint family, member 12 /// neuroblastoma breakpoint family, member 14 /// neuroblastoma breakpoint family, member 15 /// neuroblastoma breakpoint family, member 16 /// neuroblastoma breakpoint family, member 20 /// neuroblastoma breakpoint family, member 8 /// neuroblastoma breakpoint family, member 9 /// hypothetical protein LOC200030 KIAA1245 /// NBPF1 /// NBPF10 /// NBPF11 /// NBPF12 /// NBPF14 /// NBPF15 /// NBPF16 /// NBPF20 /// NBPF8 /// NBPF9 /// RP11-94I2.2 100132406 /// 149013 /// 200030 /// 25832 /// 284565 /// 400818 /// 440670 /// 440675 /// 55672 /// 728841 /// 728912 /// 728936 NM_001037675 /// NM_001039703 /// NM_001101663 /// NM_001102663 /// NM_015383 /// NM_017940 /// NM_173638 /// NM_183372 /// XM_001715810 /// XM_001717398 /// XM_001717802 /// XM_001721345 /// XM_001721349 /// XM_001722184 /// XM_001723523 /// XM_001726946 0005737 // cytoplasm // inferred from electronic annotation 201105_at NM_002305 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002305.2 /DEF=Homo sapiens lectin, galactoside-binding, soluble, 1 (galectin 1) (LGALS1), mRNA. /FEA=mRNA /GEN=LGALS1 /PROD=beta-galactosidase binding lectin precursor /DB_XREF=gi:6006015 /UG=Hs.227751 lectin, galactoside-binding, soluble, 1 (galectin 1) /FL=gb:BC001693.1 gb:J04456.1 gb:NM_002305.2 NM_002305 lectin, galactoside-binding, soluble, 1 LGALS1 3956 NM_002305 0006915 // apoptosis // traceable author statement /// 0042981 // regulation of apoptosis // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0045445 // myoblast differentiation // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from physical interaction /// 0005529 // sugar binding // inferred from electronic annotation /// 0016936 // galactoside binding // inferred from electronic annotation 201106_at NM_002085 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002085.1 /DEF=Homo sapiens glutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4), mRNA. /FEA=mRNA /GEN=GPX4 /PROD=glutathione peroxidase 4 /DB_XREF=gi:4504106 /UG=Hs.2706 glutathione peroxidase 4 (phospholipid hydroperoxidase) /FL=gb:NM_002085.1 NM_002085 glutathione peroxidase 4 (phospholipid hydroperoxidase) GPX4 2879 NM_001039847 /// NM_001039848 /// NM_002085 0006325 // establishment or maintenance of chromatin architecture // inferred from electronic annotation /// 0006644 // phospholipid metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0050727 // regulation of inflammatory response // inferred from electronic annotation /// 0055114 // oxidation reduction // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // traceable author statement /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from electronic annotation /// 0047066 // phospholipid-hydroperoxide glutathione peroxidase activity // inferred from electronic annotation 201107_s_at AI812030 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI812030 /FEA=EST /DB_XREF=gi:5398596 /DB_XREF=est:tw46c12.x1 /CLONE=IMAGE:2262742 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AI812030 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0008632 // apoptotic program // inferred from expression pattern /// 0009749 // response to glucose stimulus // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010670 // positive regulation of oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone stimulus // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // non-traceable author statement /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion formation // traceable author statement /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // not recorded 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from physical interaction /// 0030169 // low-density lipoprotein binding // inferred from physical interaction /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from physical interaction /// 0043394 // proteoglycan binding // traceable author statement /// 0043499 // eukaryotic cell surface binding // inferred from direct assay /// 0048603 // fibroblast growth factor 2 binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0070051 // fibrinogen binding // inferred from physical interaction /// 0070052 // collagen V binding // inferred from physical interaction 201108_s_at BF055462 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF055462 /FEA=EST /DB_XREF=gi:10809358 /DB_XREF=est:7j80e06.x1 /CLONE=IMAGE:3392770 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 BF055462 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0008632 // apoptotic program // inferred from expression pattern /// 0009749 // response to glucose stimulus // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010670 // positive regulation of oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone stimulus // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // non-traceable author statement /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion formation // traceable author statement /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // not recorded 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from physical interaction /// 0030169 // low-density lipoprotein binding // inferred from physical interaction /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from physical interaction /// 0043394 // proteoglycan binding // traceable author statement /// 0043499 // eukaryotic cell surface binding // inferred from direct assay /// 0048603 // fibroblast growth factor 2 binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0070051 // fibrinogen binding // inferred from physical interaction /// 0070052 // collagen V binding // inferred from physical interaction 201109_s_at AV726673 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV726673 /FEA=EST /DB_XREF=gi:10836094 /DB_XREF=est:AV726673 /CLONE=HTCBGC12 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 AV726673 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0008632 // apoptotic program // inferred from expression pattern /// 0009749 // response to glucose stimulus // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010670 // positive regulation of oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone stimulus // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // non-traceable author statement /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion formation // traceable author statement /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // not recorded 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from physical interaction /// 0030169 // low-density lipoprotein binding // inferred from physical interaction /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from physical interaction /// 0043394 // proteoglycan binding // traceable author statement /// 0043499 // eukaryotic cell surface binding // inferred from direct assay /// 0048603 // fibroblast growth factor 2 binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0070051 // fibrinogen binding // inferred from physical interaction /// 0070052 // collagen V binding // inferred from physical interaction 201110_s_at NM_003246 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003246.1 /DEF=Homo sapiens thrombospondin 1 (THBS1), mRNA. /FEA=mRNA /GEN=THBS1 /PROD=thrombospondin 1 /DB_XREF=gi:4507484 /UG=Hs.87409 thrombospondin 1 /FL=gb:NM_003246.1 NM_003246 thrombospondin 1 THBS1 7057 NM_003246 0000187 // activation of MAPK activity // inferred from mutant phenotype /// 0001666 // response to hypoxia // non-traceable author statement /// 0001937 // negative regulation of endothelial cell proliferation // inferred from direct assay /// 0001937 // negative regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0001953 // negative regulation of cell-matrix adhesion // inferred from direct assay /// 0002040 // sprouting angiogenesis // inferred from mutant phenotype /// 0002544 // chronic inflammatory response // inferred from expression pattern /// 0002581 // negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from direct assay /// 0002605 // negative regulation of dendritic cell antigen processing and presentation // inferred from direct assay /// 0006916 // anti-apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0007050 // cell cycle arrest // inferred from direct assay /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0008632 // apoptotic program // inferred from expression pattern /// 0009749 // response to glucose stimulus // inferred from direct assay /// 0010595 // positive regulation of endothelial cell migration // inferred from direct assay /// 0010596 // negative regulation of endothelial cell migration // inferred from direct assay /// 0010670 // positive regulation of oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0010748 // negative regulation of plasma membrane long-chain fatty acid transport // inferred from direct assay /// 0010751 // negative regulation of nitric oxide mediated signal transduction // inferred from direct assay /// 0010754 // negative regulation of cGMP-mediated signaling // inferred from direct assay /// 0010757 // negative regulation of plasminogen activation // inferred from direct assay /// 0010759 // positive regulation of macrophage chemotaxis // inferred from sequence or structural similarity /// 0010763 // positive regulation of fibroblast cell migration // inferred from direct assay /// 0016477 // cell migration // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from direct assay /// 0016525 // negative regulation of angiogenesis // inferred from electronic annotation /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030194 // positive regulation of blood coagulation // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030335 // positive regulation of cell migration // inferred from mutant phenotype /// 0030511 // positive regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0032026 // response to magnesium ion // inferred from direct assay /// 0032570 // response to progesterone stimulus // traceable author statement /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from sequence or structural similarity /// 0034605 // cellular response to heat // non-traceable author statement /// 0040037 // negative regulation of fibroblast growth factor receptor signaling pathway // inferred from direct assay /// 0042327 // positive regulation of phosphorylation // inferred from mutant phenotype /// 0043032 // positive regulation of macrophage activation // inferred from direct assay /// 0043536 // positive regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043537 // negative regulation of blood vessel endothelial cell migration // inferred from direct assay /// 0043652 // engulfment of apoptotic cell // inferred from direct assay /// 0045727 // positive regulation of translation // inferred from direct assay /// 0045766 // positive regulation of angiogenesis // inferred from mutant phenotype /// 0050921 // positive regulation of chemotaxis // inferred from direct assay /// 0051592 // response to calcium ion // inferred from direct assay /// 0051895 // negative regulation of focal adhesion formation // traceable author statement /// 0051918 // negative regulation of fibrinolysis // inferred from direct assay 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // inferred from electronic annotation /// 0005577 // fibrinogen complex // inferred from direct assay /// 0005615 // extracellular space // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from direct assay /// 0031012 // extracellular matrix // traceable author statement /// 0031091 // platelet alpha granule // inferred from direct assay /// 0031093 // platelet alpha granule lumen // not recorded 0001948 // glycoprotein binding // non-traceable author statement /// 0001968 // fibronectin binding // inferred from physical interaction /// 0005178 // integrin binding // inferred from mutant phenotype /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008201 // heparin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from physical interaction /// 0030169 // low-density lipoprotein binding // inferred from physical interaction /// 0042802 // identical protein binding // non-traceable author statement /// 0043236 // laminin binding // inferred from physical interaction /// 0043394 // proteoglycan binding // traceable author statement /// 0043499 // eukaryotic cell surface binding // inferred from direct assay /// 0048603 // fibroblast growth factor 2 binding // inferred from direct assay /// 0050431 // transforming growth factor beta binding // inferred from sequence or structural similarity /// 0050431 // transforming growth factor beta binding // traceable author statement /// 0070051 // fibrinogen binding // inferred from physical interaction /// 0070052 // collagen V binding // inferred from physical interaction 201111_at AF053641 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF053641.1 /DEF=Homo sapiens brain cellular apoptosis susceptibility protein (CSE1) mRNA, complete cds. /FEA=mRNA /GEN=CSE1 /PROD=cellular apoptosis susceptibility protein /DB_XREF=gi:3560556 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1 AF053641 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001316 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008262 // importin-alpha export receptor activity // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 201112_s_at NM_001316 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001316.1 /DEF=Homo sapiens chromosome segregation 1 (yeast homolog)-like (CSE1L), mRNA. /FEA=mRNA /GEN=CSE1L /PROD=chromosome segregation 1 (yeast homolog)-like /DB_XREF=gi:4503072 /UG=Hs.90073 chromosome segregation 1 (yeast homolog)-like /FL=gb:U33286.1 gb:AF053641.1 gb:NM_001316.1 NM_001316 CSE1 chromosome segregation 1-like (yeast) CSE1L 1434 NM_001316 0000059 // protein import into nucleus, docking // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006915 // apoptosis // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008262 // importin-alpha export receptor activity // traceable author statement /// 0008262 // importin-alpha export receptor activity // inferred from electronic annotation /// 0008565 // protein transporter activity // inferred from electronic annotation 201113_at NM_003321 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003321.1 /DEF=Homo sapiens Tu translation elongation factor, mitochondrial (TUFM), mRNA. /FEA=mRNA /GEN=TUFM /PROD=Tu translation elongation factor, mitochondrial /DB_XREF=gi:4507732 /UG=Hs.12084 Tu translation elongation factor, mitochondrial /FL=gb:BC001633.1 gb:NM_003321.1 gb:L38995.1 NM_003321 Tu translation elongation factor, mitochondrial TUFM 7284 NM_003321 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from direct assay /// 0006414 // translational elongation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from direct assay /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201114_x_at NM_002792 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002792.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7), mRNA. /FEA=mRNA /GEN=PSMA7 /PROD=proteasome (prosome, macropain) subunit, alphatype, 7 /DB_XREF=gi:4506188 /UG=Hs.233952 proteasome (prosome, macropain) subunit, alpha type, 7 /FL=gb:BC004427.1 gb:AF022815.1 gb:AF054185.1 gb:NM_002792.1 NM_002792 proteasome (prosome, macropain) subunit, alpha type, 7 PSMA7 5688 NM_002792 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201115_at NM_006230 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006230.1 /DEF=Homo sapiens polymerase (DNA directed), delta 2, regulatory subunit (50kD) (POLD2), mRNA. /FEA=mRNA /GEN=POLD2 /PROD=polymerase (DNA directed), delta 2, regulatorysubunit (50kD) /DB_XREF=gi:5453923 /UG=Hs.74598 polymerase (DNA directed), delta 2, regulatory subunit (50kD) /FL=gb:U21090.1 gb:BC000459.1 gb:NM_006230.1 NM_006230 polymerase (DNA directed), delta 2, regulatory subunit 50kDa POLD2 5425 NM_001127218 /// NM_006230 0006260 // DNA replication // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003887 // DNA-directed DNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation 201116_s_at AI922855 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI922855 /FEA=EST /DB_XREF=gi:5658819 /DB_XREF=est:wo14h05.x1 /CLONE=IMAGE:2455353 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1 AI922855 carboxypeptidase E CPE 1363 NM_001873 0006464 // protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201117_s_at NM_001873 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001873.1 /DEF=Homo sapiens carboxypeptidase E (CPE), mRNA. /FEA=mRNA /GEN=CPE /PROD=carboxypeptidase E precursor /DB_XREF=gi:4503008 /UG=Hs.75360 carboxypeptidase E /FL=gb:NM_001873.1 NM_001873 carboxypeptidase E CPE 1363 NM_001873 0006464 // protein modification process // non-traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007218 // neuropeptide signaling pathway // non-traceable author statement /// 0008152 // metabolic process // traceable author statement /// 0030070 // insulin processing // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // traceable author statement /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201118_at NM_002631 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002631.1 /DEF=Homo sapiens phosphogluconate dehydrogenase (PGD), mRNA. /FEA=mRNA /GEN=PGD /PROD=phosphogluconate dehydrogenase /DB_XREF=gi:4505758 /UG=Hs.75888 phosphogluconate dehydrogenase /FL=gb:BC000368.1 gb:NM_002631.1 gb:U30255.1 NM_002631 phosphogluconate dehydrogenase PGD 5226 NM_002631 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009051 // pentose-phosphate shunt, oxidative branch // inferred from direct assay /// 0019322 // pentose biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004616 // phosphogluconate dehydrogenase (decarboxylating) activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201119_s_at NM_004074 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004074.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIII (COX8), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX8 /PROD=cytochrome c oxidase subunit VIII /DB_XREF=gi:4758043 /UG=Hs.81097 cytochrome c oxidase subunit VIII /FL=gb:NM_004074.1 NM_004074 cytochrome c oxidase subunit 8A (ubiquitous) COX8A 1351 NM_004074 0006091 // generation of precursor metabolites and energy // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201120_s_at AL547946 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL547946 /FEA=EST /DB_XREF=gi:12882489 /DB_XREF=est:AL547946 /CLONE=CS0DI035YB22 (5 prime) /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2 AL547946 progesterone receptor membrane component 1 PGRMC1 10857 NM_006667 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201121_s_at NM_006667 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006667.2 /DEF=Homo sapiens progesterone binding protein (HPR6.6), mRNA. /FEA=mRNA /GEN=HPR6.6 /PROD=progesterone binding protein /DB_XREF=gi:6857798 /UG=Hs.90061 progesterone binding protein /FL=gb:NM_006667.2 NM_006667 progesterone receptor membrane component 1 PGRMC1 10857 NM_006667 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201122_x_at BC000751 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000751.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 5A, clone MGC:2453, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:12653914 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1 BC000751 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_001724572 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006917 // induction of apoptosis // inferred from direct assay /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008612 // peptidyl-lysine modification to hypusine // not recorded /// 0019079 // viral genome replication // traceable author statement /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201123_s_at NM_001970 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001970.1 /DEF=Homo sapiens eukaryotic translation initiation factor 5A (EIF5A), mRNA. /FEA=mRNA /GEN=EIF5A /PROD=eukaryotic translation initiation factor 5A /DB_XREF=gi:4503544 /UG=Hs.119140 eukaryotic translation initiation factor 5A /FL=gb:BC000751.1 gb:BC001832.1 gb:M23419.1 gb:NM_001970.1 NM_001970 eukaryotic translation initiation factor 5A EIF5A 1984 NM_001143760 /// NM_001143761 /// NM_001143762 /// NM_001970 /// XM_001724572 0006406 // mRNA export from nucleus // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006611 // protein export from nucleus // inferred from mutant phenotype /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0006913 // nucleocytoplasmic transport // inferred from mutant phenotype /// 0006917 // induction of apoptosis // inferred from direct assay /// 0008283 // cell proliferation // inferred from mutant phenotype /// 0008612 // peptidyl-lysine modification to hypusine // not recorded /// 0019079 // viral genome replication // traceable author statement /// 0045948 // positive regulation of translational initiation // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005642 // annulate lamellae // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0003723 // RNA binding // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0017070 // U6 snRNA binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from physical interaction 201124_at AL048423 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL048423 /FEA=EST /DB_XREF=gi:5936493 /DB_XREF=est:DKFZp586H2324_s1 /CLONE=DKFZp586H2324 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1 AL048423 integrin, beta 5 ITGB5 3693 NM_002213 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201125_s_at NM_002213 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002213.1 /DEF=Homo sapiens integrin, beta 5 (ITGB5), mRNA. /FEA=mRNA /GEN=ITGB5 /PROD=integrin, beta 5 /DB_XREF=gi:4504772 /UG=Hs.149846 integrin, beta 5 /FL=gb:M35011.1 gb:J05633.1 gb:NM_002213.1 NM_002213 integrin, beta 5 ITGB5 3693 NM_002213 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201126_s_at NM_002406 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002406.2 /DEF=Homo sapiens mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (MGAT1), mRNA. /FEA=mRNA /GEN=MGAT1 /PROD=mannosyl (alpha-1,3-)-glycoproteinbeta-1,2-N-acetylglucosaminyltransferase /DB_XREF=gi:6031182 /UG=Hs.151513 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase /FL=gb:M55621.1 gb:NM_002406.2 NM_002406 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase MGAT1 4245 NM_001114617 /// NM_001114618 /// NM_001114619 /// NM_001114620 /// NM_002406 0005975 // carbohydrate metabolic process // traceable author statement /// 0006486 // protein amino acid glycosylation // traceable author statement /// 0006487 // protein amino acid N-linked glycosylation // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0003827 // alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity // inferred from electronic annotation /// 0008375 // acetylglucosaminyltransferase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 201127_s_at AI971281 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI971281 /FEA=EST /DB_XREF=gi:5768107 /DB_XREF=est:wr27d10.x1 /CLONE=IMAGE:2488915 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1 AI971281 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 0006101 // citrate metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0009346 // citrate lyase complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0003878 // ATP citrate synthase activity // inferred from electronic annotation /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008815 // citrate (pro-3S)-lyase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation 201128_s_at NM_001096 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001096.1 /DEF=Homo sapiens ATP citrate lyase (ACLY), mRNA. /FEA=mRNA /GEN=ACLY /PROD=ATP citrate lyase /DB_XREF=gi:4501864 /UG=Hs.174140 ATP citrate lyase /FL=gb:NM_001096.1 NM_001096 ATP citrate lyase ACLY 47 NM_001096 /// NM_198830 0006101 // citrate metabolic process // traceable author statement /// 0006200 // ATP catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0015936 // coenzyme A metabolic process // traceable author statement /// 0044262 // cellular carbohydrate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0009346 // citrate lyase complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0003878 // ATP citrate synthase activity // traceable author statement /// 0003878 // ATP citrate synthase activity // inferred from electronic annotation /// 0004775 // succinate-CoA ligase (ADP-forming) activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008815 // citrate (pro-3S)-lyase activity // not recorded /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046912 // transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer // inferred from electronic annotation 201129_at NM_006276 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006276.2 /DEF=Homo sapiens splicing factor, arginineserine-rich 7 (35kD) (SFRS7), mRNA. /FEA=mRNA /GEN=SFRS7 /PROD=splicing factor, arginineserine-rich 7 (35kD) /DB_XREF=gi:6857827 /UG=Hs.184167 splicing factor, arginineserine-rich 7 (35kD) /FL=gb:BC000997.2 gb:L22253.1 gb:NM_006276.2 NM_006276 splicing factor, arginine/serine-rich 7, 35kDa SFRS7 6432 NM_001031684 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from direct assay /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201130_s_at L08599 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:L08599.1 /DEF=Human uvomorulin (E-cadherin) (UVO) mRNA, complete cds. /FEA=mRNA /GEN=UVO /PROD=uvomorulin /DB_XREF=gi:340184 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1 L08599 cadherin 1, type 1, E-cadherin (epithelial) CDH1 999 NM_004360 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0016337 // cell-cell adhesion // inferred from direct assay /// 0016337 // cell-cell adhesion // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of caspase activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from direct assay /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201131_s_at NM_004360 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004360.1 /DEF=Homo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1), mRNA. /FEA=mRNA /GEN=CDH1 /PROD=cadherin 1, type 1, E-cadherin (epithelial) /DB_XREF=gi:4757959 /UG=Hs.194657 cadherin 1, type 1, E-cadherin (epithelial) /FL=gb:L08599.1 gb:NM_004360.1 NM_004360 cadherin 1, type 1, E-cadherin (epithelial) CDH1 999 NM_004360 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // non-traceable author statement /// 0016337 // cell-cell adhesion // inferred from direct assay /// 0016337 // cell-cell adhesion // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation /// 0042993 // positive regulation of transcription factor import into nucleus // inferred from direct assay /// 0043281 // regulation of caspase activity // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005912 // adherens junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from direct assay /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030054 // cell junction // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008013 // beta-catenin binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from direct assay /// 0050839 // cell adhesion molecule binding // non-traceable author statement 201132_at NM_019597 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_019597.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein H2 (H) (HNRPH2), mRNA. /FEA=mRNA /GEN=HNRPH2 /PROD=heterogeneous nuclear ribonucleoprotein H2 (H) /DB_XREF=gi:9624997 /UG=Hs.278857 heterogeneous nuclear ribonucleoprotein H2 (H) /FL=gb:NM_019597.1 NM_019597 heterogeneous nuclear ribonucleoprotein H2 (H') HNRNPH2 3188 NM_001032393 /// NM_019597 0000398 // nuclear mRNA splicing, via spliceosome // not recorded 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201133_s_at AA142966 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA142966 /FEA=EST /DB_XREF=gi:1712344 /DB_XREF=est:zl43b05.s1 /CLONE=IMAGE:504657 /UG=Hs.279849 KIAA0438 gene product /FL=gb:AB007898.1 gb:NM_014819.1 AA142966 praja ring finger 2 PJA2 9867 NM_014819 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201134_x_at NM_001867 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001867.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIc (COX7C), mRNA. /FEA=mRNA /GEN=COX7C /PROD=cytochrome c oxidase subunit VIIc /DB_XREF=gi:4502992 /UG=Hs.3462 cytochrome c oxidase subunit VIIc /FL=gb:BC001005.1 gb:NM_001867.1 NM_001867 cytochrome c oxidase subunit VIIc COX7C 1350 NM_001867 0006091 // generation of precursor metabolites and energy // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201135_at NM_004092 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004092.2 /DEF=Homo sapiens enoyl Coenzyme A hydratase, short chain, 1, mitochondrial (ECHS1), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ECHS1 /PROD=mitochondrial short-chain enoyl-coenzyme Ahydratase 1 precursor /DB_XREF=gi:12707569 /UG=Hs.76394 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial /FL=gb:NM_004092.2 gb:D13900.1 NM_004092 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial ECHS1 1892 NM_004092 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004300 // enoyl-CoA hydratase activity // not recorded /// 0004300 // enoyl-CoA hydratase activity // traceable author statement /// 0004300 // enoyl-CoA hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016829 // lyase activity // inferred from electronic annotation 201136_at NM_002668 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002668.1 /DEF=Homo sapiens proteolipid protein 2 (colonic epithelium-enriched) (PLP2), mRNA. /FEA=mRNA /GEN=PLP2 /PROD=proteolipid protein 2 (colonicepithelium-enriched) /DB_XREF=gi:4505892 /UG=Hs.77422 proteolipid protein 2 (colonic epithelium-enriched) /FL=gb:L09604.1 gb:NM_002668.1 NM_002668 proteolipid protein 2 (colonic epithelium-enriched) PLP2 5355 NM_002668 0006811 // ion transport // traceable author statement /// 0006935 // chemotaxis // non-traceable author statement /// 0019221 // cytokine-mediated signaling pathway // non-traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0019956 // chemokine binding // inferred from physical interaction 201137_s_at NM_002121 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002121.1 /DEF=Homo sapiens major histocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA. /FEA=mRNA /GEN=HLA-DPB1 /PROD=major histocompatibility complex, class II, DPbeta 1 /DB_XREF=gi:4504404 /UG=Hs.814 major histocompatibility complex, class II, DP beta 1 /FL=gb:J03041.1 gb:M57466.1 gb:M83664.1 gb:NM_002121.1 gb:M28200.1 gb:M28202.1 NM_002121 major histocompatibility complex, class II, DP beta 1 HLA-DPB1 3115 NM_002121 0002504 // antigen processing and presentation of peptide or polysaccharide antigen via MHC class II // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0009405 // pathogenesis // traceable author statement /// 0019882 // antigen processing and presentation // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042613 // MHC class II protein complex // inferred from electronic annotation 0032395 // MHC class II receptor activity // traceable author statement 201138_s_at BG532929 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG532929 /FEA=EST /DB_XREF=gi:13524468 /DB_XREF=est:602580582F1 /CLONE=IMAGE:4718180 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1 BG532929 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_003142 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201139_s_at NM_003142 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003142.1 /DEF=Homo sapiens Sjogren syndrome antigen B (autoantigen La) (SSB), mRNA. /FEA=mRNA /GEN=SSB /PROD=autoantigen La /DB_XREF=gi:10835066 /UG=Hs.83715 Sjogren syndrome antigen B (autoantigen La) /FL=gb:NM_003142.1 gb:BC001289.1 gb:J04205.1 NM_003142 Sjogren syndrome antigen B (autoantigen La) SSB 6741 NM_003142 0006396 // RNA processing // inferred from electronic annotation /// 0006400 // tRNA modification // traceable author statement /// 0008334 // histone mRNA metabolic process // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000049 // tRNA binding // traceable author statement /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201140_s_at NM_004583 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004583.1 /DEF=Homo sapiens RAB5C, member RAS oncogene family (RAB5C), mRNA. /FEA=mRNA /GEN=RAB5C /PROD=RAB5C, member RAS oncogene family /DB_XREF=gi:4759019 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1 NM_004583 RAB5C, member RAS oncogene family RAB5C 5878 NM_004583 /// NM_201434 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201141_at NM_002510 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002510.1 /DEF=Homo sapiens glycoprotein (transmembrane) nmb (GPNMB), mRNA. /FEA=mRNA /GEN=GPNMB /PROD=glycoprotein (transmembrane) nmb /DB_XREF=gi:4505404 /UG=Hs.82226 glycoprotein (transmembrane) nmb /FL=gb:AF322909.1 gb:NM_002510.1 NM_002510 glycoprotein (transmembrane) nmb GPNMB 10457 NM_001005340 /// NM_002510 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0030282 // bone mineralization // inferred from electronic annotation 0005887 // integral to plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005178 // integrin binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation 201142_at AA577698 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA577698 /FEA=EST /DB_XREF=gi:2355882 /DB_XREF=est:nn22h05.s1 /CLONE=IMAGE:1084665 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 AA577698 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201143_s_at BC002513 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002513.1 /DEF=Homo sapiens, eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ), clone MGC:1511, mRNA, complete cds. /FEA=mRNA /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:12803384 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 BC002513 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201144_s_at NM_004094 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004094.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) (EIF2S1), mRNA. /FEA=mRNA /GEN=EIF2S1 /PROD=eukaryotic translation initiation factor 2,subunit 1 (alpha, 35kD ) /DB_XREF=gi:4758255 /UG=Hs.151777 eukaryotic translation initiation factor 2, subunit 1 (alpha, 35kD ) /FL=gb:BC002513.1 gb:J02645.1 gb:NM_004094.1 NM_004094 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa EIF2S1 1965 NM_004094 0006412 // translation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0043558 // regulation of translational initiation in response to stress // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005844 // polysome // traceable author statement /// 0005850 // eukaryotic translation initiation factor 2 complex // inferred from electronic annotation /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201145_at NM_006118 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006118.2 /DEF=Homo sapiens HS1 binding protein (HAX1), mRNA. /FEA=mRNA /GEN=HAX1 /PROD=HS1 binding protein /DB_XREF=gi:13435355 /UG=Hs.15318 HS1 binding protein /FL=gb:NM_006118.2 gb:BC005240.1 gb:U68566.1 NM_006118 HCLS1 associated protein X-1 HAX1 10456 NM_001018837 /// NM_006118 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0015629 // actin cytoskeleton // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019966 // interleukin-1 binding // inferred from direct assay /// 0047485 // protein N-terminus binding // inferred from direct assay 201146_at NM_006164 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006164.1 /DEF=Homo sapiens nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), mRNA. /FEA=mRNA /GEN=NFE2L2 /PROD=nuclear factor (erythroid-derived 2)-like 2 /DB_XREF=gi:5453775 /UG=Hs.155396 nuclear factor (erythroid-derived 2)-like 2 /FL=gb:NM_006164.1 NM_006164 nuclear factor (erythroid-derived 2)-like 2 NFE2L2 4780 NM_006164 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0045941 // positive regulation of transcription // inferred from electronic annotation /// 0045995 // regulation of embryonic development // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201147_s_at BF347089 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF347089 /FEA=EST /DB_XREF=gi:11294684 /DB_XREF=est:602020842F1 /CLONE=IMAGE:4156354 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 BF347089 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // non-traceable author statement /// 0014070 // response to organic cyclic substance // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement 201148_s_at AW338933 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW338933 /FEA=EST /DB_XREF=gi:6835559 /DB_XREF=est:ha68g07.x1 /CLONE=IMAGE:2878908 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 AW338933 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // non-traceable author statement /// 0014070 // response to organic cyclic substance // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement 201149_s_at U67195 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U67195.1 /DEF=Human tissue inhibitor of metalloproteinase-3 mRNA, complete cds. /FEA=mRNA /PROD=tissue inhibitor of metalloproteinase-3 /DB_XREF=gi:1519557 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 U67195 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // non-traceable author statement /// 0014070 // response to organic cyclic substance // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement 201150_s_at NM_000362 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000362.2 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) (TIMP3), mRNA. /FEA=mRNA /GEN=TIMP3 /PROD=tissue inhibitor of metalloproteinase 3precursor /DB_XREF=gi:9257248 /UG=Hs.245188 tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) /FL=gb:U67195.1 gb:U02571.1 gb:U14394.1 gb:NM_000362.2 NM_000362 TIMP metallopeptidase inhibitor 3 TIMP3 7078 NM_000362 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // non-traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008624 // induction of apoptosis by extracellular signals // non-traceable author statement /// 0014070 // response to organic cyclic substance // inferred from electronic annotation /// 0042246 // tissue regeneration // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0050896 // response to stimulus // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation /// 0008191 // metalloendopeptidase inhibitor activity // traceable author statement 201151_s_at BF512200 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF512200 /FEA=EST /DB_XREF=gi:11597379 /DB_XREF=est:UI-H-BI3-alq-d-11-0-UI.s1 /CLONE=IMAGE:3068228 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 BF512200 muscleblind-like (Drosophila) MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007517 // muscle development // inferred from electronic annotation /// 0007517 // muscle development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201152_s_at N31913 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N31913 /FEA=EST /DB_XREF=gi:1152312 /DB_XREF=est:yy21f10.s1 /CLONE=IMAGE:271915 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 N31913 muscleblind-like (Drosophila) MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007517 // muscle development // inferred from electronic annotation /// 0007517 // muscle development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201153_s_at NM_021038 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021038.1 /DEF=Homo sapiens muscleblind (Drosophila)-like (MBNL), mRNA. /FEA=mRNA /GEN=MBNL /PROD=muscleblind (Drosophila)-like /DB_XREF=gi:10518339 /UG=Hs.28578 muscleblind (Drosophila)-like /FL=gb:NM_021038.1 gb:AB007888.1 NM_021038 muscleblind-like (Drosophila) MBNL1 4154 NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from sequence or structural similarity /// 0006376 // mRNA splice site selection // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0007517 // muscle development // inferred from electronic annotation /// 0007517 // muscle development // inferred from sequence or structural similarity /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from electronic annotation /// 0030326 // embryonic limb morphogenesis // inferred from sequence or structural similarity /// 0045445 // myoblast differentiation // inferred from electronic annotation /// 0045445 // myoblast differentiation // inferred from sequence or structural similarity 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201154_x_at NM_000968 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000968.1 /DEF=Homo sapiens ribosomal protein L4 (RPL4), mRNA. /FEA=mRNA /GEN=RPL4 /PROD=ribosomal protein L4 /DB_XREF=gi:4506652 /UG=Hs.286 ribosomal protein L4 /FL=gb:BC001365.1 gb:L20868.1 gb:D23660.1 gb:NM_000968.1 NM_000968 ribosomal protein L4 RPL4 6124 NM_000968 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0008152 // metabolic process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201155_s_at NM_014874 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014874.1 /DEF=Homo sapiens KIAA0214 gene product (KIAA0214), mRNA. /FEA=mRNA /GEN=KIAA0214 /PROD=KIAA0214 gene product /DB_XREF=gi:7662003 /UG=Hs.3363 KIAA0214 gene product /FL=gb:D86987.1 gb:AF036536.1 gb:NM_014874.1 NM_014874 mitofusin 2 MFN2 9927 NM_001127660 /// NM_014874 0001825 // blastocyst formation // inferred from electronic annotation /// 0006626 // protein targeting to mitochondrion // inferred from direct assay /// 0007006 // mitochondrial membrane organization // inferred from direct assay /// 0007050 // cell cycle arrest // inferred from sequence or structural similarity /// 0008053 // mitochondrial fusion // non-traceable author statement /// 0008053 // mitochondrial fusion // inferred from electronic annotation /// 0046580 // negative regulation of Ras protein signal transduction // inferred from direct assay /// 0048593 // camera-type eye morphogenesis // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from sequence or structural similarity /// 0051646 // mitochondrion localization // inferred from direct assay 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0015630 // microtubule cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031306 // intrinsic to mitochondrial outer membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201156_s_at AF141304 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF141304.1 /DEF=Homo sapiens small GTPase (RAB5C) mRNA, complete cds. /FEA=CDS /GEN=RAB5C /PROD=small GTPase /DB_XREF=gi:7672664 /UG=Hs.479 RAB5C, member RAS oncogene family /FL=gb:NM_004583.1 gb:U11293.1 gb:U18420.1 gb:AF141304.1 AF141304 RAB5C, member RAS oncogene family RAB5C 5878 NM_004583 /// NM_201434 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation 201157_s_at AF020500 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF020500.1 /DEF=Homo sapiens myristoyl CoA:protein N-myristoyltransferase mRNA, complete cds. /FEA=CDS /PROD=myristoyl CoA:protein N-myristoyltransferase /DB_XREF=gi:2760893 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 AF020500 N-myristoyltransferase 1 NMT1 4836 NM_021079 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0009249 // protein lipoylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201158_at AI570834 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI570834 /FEA=EST /DB_XREF=gi:4534208 /DB_XREF=est:tr67g09.x1 /CLONE=IMAGE:2223424 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 AI570834 N-myristoyltransferase 1 NMT1 4836 NM_021079 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0009249 // protein lipoylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201159_s_at NM_021079 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021079.1 /DEF=Homo sapiens N-myristoyltransferase 1 (NMT1), mRNA. /FEA=mRNA /GEN=NMT1 /PROD=N-myristoyltransferase 1 /DB_XREF=gi:10835072 /UG=Hs.111039 N-myristoyltransferase 1 /FL=gb:NM_021079.1 gb:AF020500.1 gb:AF043324.1 NM_021079 N-myristoyltransferase 1 NMT1 4836 NM_021079 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006498 // N-terminal protein lipidation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // non-traceable author statement /// 0006499 // N-terminal protein myristoylation // inferred from electronic annotation /// 0009249 // protein lipoylation // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003824 // catalytic activity // traceable author statement /// 0004379 // glycylpeptide N-tetradecanoyltransferase activity // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201160_s_at AL556190 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL556190 /FEA=EST /DB_XREF=gi:12898634 /DB_XREF=est:AL556190 /CLONE=CS0DK011YH09 (5 prime) /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1 AL556190 cold shock domain protein A CSDA 8531 NM_003651 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // transcription factor activity // non-traceable author statement /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201161_s_at NM_003651 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003651.1 /DEF=Homo sapiens cold shock domain protein A (CSDA), mRNA. /FEA=mRNA /GEN=CSDA /PROD=cold shock domain protein A /DB_XREF=gi:4503070 /UG=Hs.1139 cold shock domain protein A /FL=gb:NM_003651.1 NM_003651 cold shock domain protein A CSDA 8531 NM_003651 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0008584 // male gonad development // inferred from electronic annotation /// 0009409 // response to cold // traceable author statement /// 0009566 // fertilization // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0046622 // positive regulation of organ growth // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003700 // transcription factor activity // non-traceable author statement /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201162_at NM_001553 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1 NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201163_s_at NM_001553 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001553.1 /DEF=Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), mRNA. /FEA=mRNA /GEN=IGFBP7 /PROD=insulin-like growth factor binding protein 7 /DB_XREF=gi:4504618 /UG=Hs.119206 insulin-like growth factor binding protein 7 /FL=gb:L19182.1 gb:NM_001553.1 NM_001553 insulin-like growth factor binding protein 7 IGFBP7 3490 NM_001553 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201164_s_at BG474429 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG474429 /FEA=EST /DB_XREF=gi:13406706 /DB_XREF=est:602517152F1 /CLONE=IMAGE:4648765 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BG474429 pumilio homolog 1 (Drosophila) PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 201165_s_at BE670915 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE670915 /FEA=EST /DB_XREF=gi:10031456 /DB_XREF=est:7e43a09.x1 /CLONE=IMAGE:3285208 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 BE670915 pumilio homolog 1 (Drosophila) PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 201166_s_at NM_014676 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014676.1 /DEF=Homo sapiens pumilio (Drosophila) homolog 1 (PUM1), mRNA. /FEA=mRNA /GEN=PUM1 /PROD=pumilio (Drosophila) homolog 1 /DB_XREF=gi:13491165 /UG=Hs.153834 pumilio (Drosophila) homolog 1 /FL=gb:AF315592.1 gb:NM_014676.1 NM_014676 pumilio homolog 1 (Drosophila) PUM1 9698 NM_001020658 /// NM_014676 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation 201167_x_at D13989 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D13989.1 /DEF=Human rho GDI mRNA, complete cds. /FEA=mRNA /PROD=human rho GDI /DB_XREF=gi:285978 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1 D13989 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_004309 0006916 // anti-apoptosis // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0005094 // Rho GDP-dissociation inhibitor activity // traceable author statement /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 201168_x_at NM_004309 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004309.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) alpha (ARHGDIA), mRNA. /FEA=mRNA /GEN=ARHGDIA /PROD=Rho GDP dissociation inhibitor (GDI) alpha /DB_XREF=gi:4757767 /UG=Hs.159161 Rho GDP dissociation inhibitor (GDI) alpha /FL=gb:D13989.1 gb:M97579.1 gb:NM_004309.1 NM_004309 Rho GDP dissociation inhibitor (GDI) alpha ARHGDIA 396 NM_004309 0006916 // anti-apoptosis // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0005094 // Rho GDP-dissociation inhibitor activity // traceable author statement /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 201169_s_at BG326045 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG326045 /FEA=EST /DB_XREF=gi:13132482 /DB_XREF=est:602424821F1 /CLONE=IMAGE:4562789 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1 BG326045 basic helix-loop-helix family, member e40 BHLHE40 8553 NM_003670 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation 201170_s_at NM_003670 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003670.1 /DEF=Homo sapiens basic helix-loop-helix domain containing, class B, 2 (BHLHB2), mRNA. /FEA=mRNA /GEN=BHLHB2 /PROD=differentiated embryo chondrocyte expressed gene1 /DB_XREF=gi:4503298 /UG=Hs.171825 basic helix-loop-helix domain containing, class B, 2 /FL=gb:AB004066.1 gb:NM_003670.1 NM_003670 basic helix-loop-helix family, member e40 BHLHE40 8553 NM_003670 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0009649 // entrainment of circadian clock // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0048168 // regulation of neuronal synaptic plasticity // inferred from electronic annotation 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation 201171_at NM_003945 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1 NM_003945 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 201172_x_at NM_003945 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003945.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD (ATP6H), mRNA. /FEA=mRNA /GEN=ATP6H /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) 9kD /DB_XREF=gi:4502318 /UG=Hs.24322 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD /FL=gb:NM_003945.1 NM_003945 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 ATP6V0E1 8992 NM_003945 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015991 // ATP hydrolysis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // traceable author statement /// 0015992 // proton transport // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0033179 // proton-transporting V-type ATPase, V0 domain // inferred from electronic annotation 0005215 // transporter activity // non-traceable author statement /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // traceable author statement 201173_x_at NM_006600 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006600.1 /DEF=Homo sapiens nuclear distribution gene C (A.nidulans) homolog (NUDC), mRNA. /FEA=mRNA /GEN=NUDC /PROD=nuclear distribution gene C (A.nidulans)homolog /DB_XREF=gi:5729952 /UG=Hs.263812 nuclear distribution gene C (A.nidulans) homolog /FL=gb:BC002399.1 gb:BC003132.1 gb:AB019408.1 gb:AF130736.1 gb:AF125465.1 gb:AF100760.1 gb:NM_006600.1 NM_006600 nuclear distribution gene C homolog (A. nidulans) NUDC 10726 NM_006600 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201174_s_at NM_018975 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018975.1 /DEF=Homo sapiens TRF2-interacting telomeric RAP1 protein (RAP1), mRNA. /FEA=mRNA /GEN=RAP1 /PROD=TRF2-interacting telomeric RAP1 protein /DB_XREF=gi:9507032 /UG=Hs.274428 TRF2-interacting telomeric RAP1 protein /FL=gb:BC004465.1 gb:AF262988.1 gb:NM_018975.1 NM_018975 telomeric repeat binding factor 2, interacting protein TERF2IP 54386 NM_018975 0007004 // telomere maintenance via telomerase // traceable author statement /// 0032205 // negative regulation of telomere maintenance // inferred from direct assay /// 0045449 // regulation of transcription // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0000781 // chromosome, telomeric region // inferred from direct assay /// 0000781 // chromosome, telomeric region // inferred from electronic annotation /// 0000783 // nuclear telomere cap complex // inferred from direct assay /// 0000784 // nuclear chromosome, telomeric region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042162 // telomeric DNA binding // traceable author statement /// 0043047 // single-stranded telomeric DNA binding // inferred from mutant phenotype 201175_at NM_015959 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015959.1 /DEF=Homo sapiens CGI-31 protein (LOC51075), mRNA. /FEA=mRNA /GEN=LOC51075 /PROD=CGI-31 protein /DB_XREF=gi:7705725 /UG=Hs.279861 CGI-31 protein /FL=gb:AF059753.1 gb:BC000666.1 gb:AF132965.1 gb:NM_015959.1 NM_015959 thioredoxin domain containing 14 TXNDC14 51075 NM_015959 0045454 // cell redox homeostasis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201176_s_at NM_001655 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001655.2 /DEF=Homo sapiens archain 1 (ARCN1), mRNA. /FEA=mRNA /GEN=ARCN1 /PROD=archain /DB_XREF=gi:11863153 /UG=Hs.33642 archain 1 /FL=gb:NM_001655.2 NM_001655 archain 1 ARCN1 372 NM_001142281 /// NM_001655 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // traceable author statement /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201177_s_at NM_005499 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005499.1 /DEF=Homo sapiens SUMO-1 activating enzyme subunit 2 (UBA2), mRNA. /FEA=mRNA /GEN=UBA2 /PROD=SUMO-1 activating enzyme subunit 2 /DB_XREF=gi:4885648 /UG=Hs.4311 SUMO-1 activating enzyme subunit 2 /FL=gb:BC003153.1 gb:U35832.1 gb:AF090384.1 gb:AF079566.1 gb:AF110957.1 gb:NM_005499.1 gb:AL136905.1 NM_005499 ubiquitin-like modifier activating enzyme 2 UBA2 10054 NM_005499 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008641 // small protein activating enzyme activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201178_at NM_012179 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012179.1 /DEF=Homo sapiens F-box only protein 7 (FBXO7), mRNA. /FEA=mRNA /GEN=FBXO7 /PROD=F-box only protein 7 /DB_XREF=gi:7106310 /UG=Hs.5912 F-box only protein 7 /FL=gb:AF129537.1 gb:NM_012179.1 gb:AF233225.1 NM_012179 F-box protein 7 FBXO7 25793 NM_001033024 /// NM_012179 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031647 // regulation of protein stability // inferred from direct assay 0000151 // ubiquitin ligase complex // traceable author statement /// 0043234 // protein complex // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201179_s_at J03005 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03005.1 /DEF=Human alternative guanine nucleotide-binding regulatory protein (G) alpha-inhibitory-subunit mRNA, complete cds. /FEA=mRNA /GEN=GNAI1 /DB_XREF=gi:183183 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 J03005 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006810 // transport // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation 201180_s_at J03198 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03198.1 /DEF=Human stimulatory G protein (of receptor-regulated K+ channels) alpha subunit mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:183224 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 J03198 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006810 // transport // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation 201181_at NM_006496 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006496.1 /DEF=Homo sapiens guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 (GNAI3), mRNA. /FEA=mRNA /GEN=GNAI3 /PROD=guanine nucleotide binding protein (G protein),alpha inhibiting activity polypeptide 3 /DB_XREF=gi:5729849 /UG=Hs.73799 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 /FL=gb:J03005.1 gb:J03198.1 gb:M27543.1 gb:J03238.1 gb:NM_006496.1 NM_006496 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 GNAI3 2773 NM_006496 0006810 // transport // non-traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0019001 // guanyl nucleotide binding // inferred from electronic annotation 201182_s_at AI761771 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI761771 /FEA=EST /DB_XREF=gi:5177362 /DB_XREF=est:wi62b06.x1 /CLONE=IMAGE:2394803 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI761771 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201183_s_at AI613273 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI613273 /FEA=EST /DB_XREF=gi:4622440 /DB_XREF=est:ty35e03.x1 /CLONE=IMAGE:2281084 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 AI613273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201184_s_at NM_001273 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001273.1 /DEF=Homo sapiens chromodomain helicase DNA binding protein 4 (CHD4), mRNA. /FEA=mRNA /GEN=CHD4 /PROD=chromodomain helicase DNA binding protein 4 /DB_XREF=gi:4557452 /UG=Hs.74441 chromodomain helicase DNA binding protein 4 /FL=gb:NM_001273.1 NM_001273 chromodomain helicase DNA binding protein 4 CHD4 1108 NM_001273 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0000785 // chromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016818 // hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201185_at NM_002775 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002775.1 /DEF=Homo sapiens protease, serine, 11 (IGF binding) (PRSS11), mRNA. /FEA=mRNA /GEN=PRSS11 /PROD=protease, serine, 11 (IGF binding) /DB_XREF=gi:4506140 /UG=Hs.75111 protease, serine, 11 (IGF binding) /FL=gb:D87258.1 gb:NM_002775.1 NM_002775 HtrA serine peptidase 1 HTRA1 5654 NM_002775 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0030512 // negative regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030514 // negative regulation of BMP signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201186_at NM_002337 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002337.1 /DEF=Homo sapiens low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) (LRPAP1), mRNA. /FEA=mRNA /GEN=LRPAP1 /PROD=low density lipoprotein-relatedprotein-associated protein 1 (alpha-2-macroglobulinreceptor-associated protein 1) /DB_XREF=gi:4505020 /UG=Hs.75140 low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1) /FL=gb:M63959.1 gb:NM_002337.1 NM_002337 low density lipoprotein receptor-related protein associated protein 1 LRPAP1 4043 NM_002337 0006457 // protein folding // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016192 // vesicle-mediated transport // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0004873 // asialoglycoprotein receptor activity // traceable author statement /// 0005509 // calcium ion binding // traceable author statement /// 0008034 // lipoprotein binding // traceable author statement /// 0008201 // heparin binding // traceable author statement /// 0008201 // heparin binding // inferred from electronic annotation /// 0050750 // low-density lipoprotein receptor binding // inferred from direct assay /// 0050750 // low-density lipoprotein receptor binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 201187_s_at BF001241 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF001241 /FEA=EST /DB_XREF=gi:10701516 /DB_XREF=est:7g96c02.x1 /CLONE=IMAGE:3314306 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 BF001241 inositol 1,4,5-triphosphate receptor, type 3 ITPR3 3710 NM_002224 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-triphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008095 // inositol-1,4,5-triphosphate receptor activity // traceable author statement /// 0008095 // inositol-1,4,5-triphosphate receptor activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphoinositide binding // inferred from electronic annotation 201188_s_at D26351 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D26351.1 /DEF=Human mRNA for type 3 inositol 1,4,5-trisphosphate receptor, complete cds. /FEA=mRNA /PROD=human type 3 inositol 1,4,5-trisphosphatereceptor /DB_XREF=gi:450470 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 D26351 inositol 1,4,5-triphosphate receptor, type 3 ITPR3 3710 NM_002224 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-triphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008095 // inositol-1,4,5-triphosphate receptor activity // traceable author statement /// 0008095 // inositol-1,4,5-triphosphate receptor activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphoinositide binding // inferred from electronic annotation 201189_s_at NM_002224 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002224.1 /DEF=Homo sapiens inositol 1,4,5-triphosphate receptor, type 3 (ITPR3), mRNA. /FEA=mRNA /GEN=ITPR3 /PROD=inositol 1,4,5-triphosphate receptor, type 3 /DB_XREF=gi:4504794 /UG=Hs.77515 inositol 1,4,5-triphosphate receptor, type 3 /FL=gb:D26351.1 gb:NM_002224.1 gb:U01062.1 NM_002224 inositol 1,4,5-triphosphate receptor, type 3 ITPR3 3710 NM_002224 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0050913 // sensory perception of bitter taste // inferred from electronic annotation /// 0050916 // sensory perception of sweet taste // inferred from electronic annotation /// 0050917 // sensory perception of umami taste // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005903 // brush border // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005216 // ion channel activity // inferred from electronic annotation /// 0005220 // inositol 1,4,5-triphosphate-sensitive calcium-release channel activity // inferred from electronic annotation /// 0005262 // calcium channel activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008095 // inositol-1,4,5-triphosphate receptor activity // traceable author statement /// 0008095 // inositol-1,4,5-triphosphate receptor activity // inferred from electronic annotation /// 0015085 // calcium ion transmembrane transporter activity // traceable author statement /// 0035091 // phosphoinositide binding // inferred from electronic annotation 201190_s_at H15647 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transmembrane transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement 201191_at H15647 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:H15647 /FEA=EST /DB_XREF=gi:880467 /DB_XREF=est:ym27b09.s1 /CLONE=IMAGE:49287 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 H15647 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transmembrane transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement 201192_s_at NM_006224 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006224.1 /DEF=Homo sapiens phosphotidylinositol transfer protein (PITPN), mRNA. /FEA=mRNA /GEN=PITPN /PROD=phosphotidylinositol transfer protein /DB_XREF=gi:5453907 /UG=Hs.79709 phosphotidylinositol transfer protein /FL=gb:D30036.1 gb:M73704.1 gb:NM_006224.1 NM_006224 phosphatidylinositol transfer protein, alpha PITPNA 5306 NM_006224 0006629 // lipid metabolic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007601 // visual perception // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0008525 // phosphatidylcholine transmembrane transporter activity // traceable author statement /// 0008526 // phosphatidylinositol transporter activity // traceable author statement 201193_at NM_005896 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005896.1 /DEF=Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble (IDH1), mRNA. /FEA=mRNA /GEN=IDH1 /PROD=isocitrate dehydrogenase 1 (NADP+), soluble /DB_XREF=gi:5174470 /UG=Hs.11223 isocitrate dehydrogenase 1 (NADP+), soluble /FL=gb:AF020038.1 gb:AF113917.1 gb:NM_005896.1 gb:AL136702.1 NM_005896 isocitrate dehydrogenase 1 (NADP+), soluble IDH1 3417 NM_005896 0005975 // carbohydrate metabolic process // traceable author statement /// 0006097 // glyoxylate cycle // inferred from electronic annotation /// 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006102 // isocitrate metabolic process // inferred from electronic annotation /// 0006102 // isocitrate metabolic process // traceable author statement /// 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004450 // isocitrate dehydrogenase (NADP+) activity // inferred from electronic annotation /// 0004450 // isocitrate dehydrogenase (NADP+) activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201194_at NM_003009 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003009.1 /DEF=Homo sapiens selenoprotein W, 1 (SEPW1), mRNA. /FEA=mRNA /GEN=SEPW1 /PROD=selenoprotein W, 1 /DB_XREF=gi:4506886 /UG=Hs.14231 selenoprotein W, 1 /FL=gb:U67171.1 gb:AF015283.1 gb:NM_003009.1 NM_003009 selenoprotein W, 1 SEPW1 6415 NM_003009 0045454 // cell redox homeostasis // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0008430 // selenium binding // inferred from electronic annotation 201195_s_at AB018009 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB018009.1 /DEF=Homo sapiens mRNA for L-type amino acid transporter 1, complete cds. /FEA=mRNA /GEN=hLAT1 /PROD=L-type amino acid transporter 1 /DB_XREF=gi:5926731 /UG=Hs.184601 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 /FL=gb:AF077866.1 gb:AB018542.1 gb:AF104032.1 gb:NM_003486.1 gb:AB017908.1 gb:AB018009.1 AB018009 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 SLC7A5 8140 NM_003486 0006520 // amino acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006865 // amino acid transport // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0015804 // neutral amino acid transport // inferred from sequence or structural similarity /// 0015807 // L-amino acid transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation 0015171 // amino acid transmembrane transporter activity // inferred from electronic annotation /// 0015171 // amino acid transmembrane transporter activity // inferred from sequence or structural similarity /// 0015175 // neutral amino acid transmembrane transporter activity // traceable author statement /// 0015179 // L-amino acid transmembrane transporter activity // inferred from electronic annotation /// 0042605 // peptide antigen binding // inferred from sequence or structural similarity 201196_s_at M21154 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M21154.1 /DEF=Human S-adenosylmethionine decarboxylase mRNA, complete cds. /FEA=mRNA /GEN=AMD2 /DB_XREF=gi:178517 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3 M21154 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001634 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // non-traceable author statement /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // non-traceable author statement 0004014 // adenosylmethionine decarboxylase activity // inferred from electronic annotation /// 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201197_at NM_001634 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001634.3 /DEF=Homo sapiens S-adenosylmethionine decarboxylase 1 (AMD1), mRNA. /FEA=mRNA /GEN=AMD1 /PROD=S-adenosylmethionine decarboxylase 1 precursor /DB_XREF=gi:5209326 /UG=Hs.262476 S-adenosylmethionine decarboxylase 1 /FL=gb:BC000171.2 gb:M21154.1 gb:NM_001634.3 NM_001634 adenosylmethionine decarboxylase 1 AMD1 262 NM_001033059 /// NM_001634 0006597 // spermine biosynthetic process // inferred from electronic annotation /// 0006597 // spermine biosynthetic process // non-traceable author statement /// 0008295 // spermidine biosynthetic process // inferred from electronic annotation /// 0008295 // spermidine biosynthetic process // non-traceable author statement 0004014 // adenosylmethionine decarboxylase activity // inferred from electronic annotation /// 0004014 // adenosylmethionine decarboxylase activity // traceable author statement /// 0016829 // lyase activity // inferred from electronic annotation /// 0016831 // carboxy-lyase activity // inferred from electronic annotation 201198_s_at AI860431 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI860431 /FEA=EST /DB_XREF=gi:5514047 /DB_XREF=est:wl13h07.x1 /CLONE=IMAGE:2424829 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1 AI860431 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 PSMD1 5707 NM_002807 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0000502 // proteasome complex // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201199_s_at NM_002807 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002807.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 (PSMD1), mRNA. /FEA=mRNA /GEN=PSMD1 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 1 /DB_XREF=gi:4506224 /UG=Hs.3887 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 /FL=gb:D44466.1 gb:NM_002807.1 NM_002807 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 PSMD1 5707 NM_002807 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0000502 // proteasome complex // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201200_at NM_003851 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003851.1 /DEF=Homo sapiens cellular repressor of E1A-stimulated genes (CREG), mRNA. /FEA=mRNA /GEN=CREG /PROD=cellular repressor of E1A-stimulated genes /DB_XREF=gi:4503036 /UG=Hs.5710 cellular repressor of E1A-stimulated genes /FL=gb:AF084523.1 gb:NM_003851.1 NM_003851 cellular repressor of E1A-stimulated genes 1 CREG1 8804 NM_003851 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement 201201_at NM_000100 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000100.1 /DEF=Homo sapiens cystatin B (stefin B) (CSTB), mRNA. /FEA=mRNA /GEN=CSTB /PROD=cystatin B (stefin B) /DB_XREF=gi:4503116 /UG=Hs.695 cystatin B (stefin B) /FL=gb:BC003370.1 gb:L03558.1 gb:NM_000100.1 NM_000100 cystatin B (stefin B) CSTB 1476 NM_000100 0008344 // adult locomotory behavior // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004866 // endopeptidase inhibitor activity // traceable author statement /// 0004869 // cysteine protease inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine protease inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201202_at NM_002592 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002592.1 /DEF=Homo sapiens proliferating cell nuclear antigen (PCNA), mRNA. /FEA=mRNA /GEN=PCNA /PROD=proliferating cell nuclear antigen /DB_XREF=gi:4505640 /UG=Hs.78996 proliferating cell nuclear antigen /FL=gb:BC000491.1 gb:M15796.1 gb:NM_002592.1 NM_002592 proliferating cell nuclear antigen PCNA 5111 NM_002592 /// NM_182649 0006260 // DNA replication // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006287 // base-excision repair, gap-filling // inferred from electronic annotation /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0048015 // phosphoinositide-mediated signaling // non-traceable author statement 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005652 // nuclear lamina // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005657 // replication fork // inferred from electronic annotation /// 0005663 // DNA replication factor C complex // traceable author statement /// 0043626 // PCNA complex // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0030337 // DNA polymerase processivity factor activity // inferred from electronic annotation /// 0032405 // MutLalpha complex binding // inferred from direct assay 201203_s_at AI921320 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI921320 /FEA=EST /DB_XREF=gi:5657284 /DB_XREF=est:wo23c10.x1 /CLONE=IMAGE:2456178 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AI921320 ribosome binding protein 1 homolog 180kDa (dog) RRBP1 6238 NM_001042576 /// NM_004587 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030176 // integral to endoplasmic reticulum membrane // non-traceable author statement /// 0030176 // integral to endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation 201204_s_at AA706065 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA706065 /FEA=EST /DB_XREF=gi:2715983 /DB_XREF=est:zf44f12.s1 /CLONE=IMAGE:379823 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AA706065 ribosome binding protein 1 homolog 180kDa (dog) RRBP1 6238 NM_001042576 /// NM_004587 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030176 // integral to endoplasmic reticulum membrane // non-traceable author statement /// 0030176 // integral to endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation 201205_at AF006751 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF006751.1 /DEF=Homo sapiens ES130 mRNA, complete cds. /FEA=mRNA /PROD=ES130 /DB_XREF=gi:3299884 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 AF006751 201206_s_at NM_004587 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004587.1 /DEF=Homo sapiens ribosome binding protein 1 (dog 180kD homolog) (RRBP1), mRNA. /FEA=mRNA /GEN=RRBP1 /PROD=ribosome binding protein 1 /DB_XREF=gi:4759055 /UG=Hs.98614 ribosome binding protein 1 (dog 180kD homolog) /FL=gb:AF006751.1 gb:NM_004587.1 NM_004587 ribosome binding protein 1 homolog 180kDa (dog) RRBP1 6238 NM_001042576 /// NM_004587 0006412 // translation // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005840 // ribosome // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030176 // integral to endoplasmic reticulum membrane // non-traceable author statement /// 0030176 // integral to endoplasmic reticulum membrane // inferred from electronic annotation 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation 201207_at NM_021137 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021137.1 /DEF=Homo sapiens tumor necrosis factor, alpha-induced protein 1 (endothelial) (TNFAIP1), mRNA. /FEA=mRNA /GEN=TNFAIP1 /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:10863936 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1 NM_021137 tumor necrosis factor, alpha-induced protein 1 (endothelial) TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from electronic annotation /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006955 // immune response // inferred from sequence or structural similarity /// 0009790 // embryonic development // inferred from sequence or structural similarity 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from sequence or structural similarity 201208_s_at BC001643 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001643.1 /DEF=Homo sapiens, tumor necrosis factor, alpha-induced protein 1 (endothelial), clone MGC:2317, mRNA, complete cds. /FEA=mRNA /PROD=tumor necrosis factor, alpha-induced protein 1(endothelial) /DB_XREF=gi:12804470 /UG=Hs.76090 tumor necrosis factor, alpha-induced protein 1 (endothelial) /FL=gb:NM_021137.1 gb:BC001643.1 gb:BC001949.1 gb:BC003694.1 gb:M80783.1 BC001643 tumor necrosis factor, alpha-induced protein 1 (endothelial) TNFAIP1 7126 NM_021137 0006260 // DNA replication // inferred from electronic annotation /// 0006260 // DNA replication // inferred from sequence or structural similarity /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006955 // immune response // inferred from expression pattern /// 0006955 // immune response // inferred from sequence or structural similarity /// 0009790 // embryonic development // inferred from sequence or structural similarity 0008076 // voltage-gated potassium channel complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005249 // voltage-gated potassium channel activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from sequence or structural similarity 201209_at NM_004964 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004964.2 /DEF=Homo sapiens histone deacetylase 1 (HDAC1), mRNA. /FEA=mRNA /GEN=HDAC1 /PROD=histone deacetylase 1 /DB_XREF=gi:13128859 /UG=Hs.88556 histone deacetylase 1 /FL=gb:BC000301.1 gb:U50079.1 gb:NM_004964.2 gb:D50405.1 NM_004964 histone deacetylase 1 HDAC1 3065 NM_004964 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement /// 0016568 // chromatin modification // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0003700 // transcription factor activity // traceable author statement /// 0004407 // histone deacetylase activity // traceable author statement /// 0004407 // histone deacetylase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201210_at NM_001356 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001356.2 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 (DDX3), transcript variant 2, mRNA. /FEA=mRNA /GEN=DDX3 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /DB_XREF=gi:13514812 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1 NM_001356 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked DDX3X 1654 NM_001356 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201211_s_at AF061337 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF061337.1 /DEF=Homo sapiens DEAD box RNA helicase DDX3 (DDX3) mRNA, complete cds. /FEA=mRNA /GEN=DDX3 /PROD=DEAD box RNA helicase DDX3 /DB_XREF=gi:3523149 /UG=Hs.147916 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 3 /FL=gb:NM_001356.2 gb:U50553.1 gb:AF000982.1 gb:AF061337.1 AF061337 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked DDX3X 1654 NM_001356 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201212_at D55696 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D55696.1 /DEF=Homo sapiens mRNA for cysteine protease, complete cds. /FEA=mRNA /PROD=cysteine protease /DB_XREF=gi:1890049 /UG=Hs.18069 protease, cysteine, 1 (legumain) /FL=gb:BC003061.1 gb:D55696.1 gb:NM_005606.1 D55696 legumain LGMN 5641 NM_001008530 /// NM_005606 0006508 // proteolysis // inferred from electronic annotation /// 0040015 // negative regulation of multicellular organism growth // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045177 // apical part of cell // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201213_at AI090331 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI090331 /FEA=EST /DB_XREF=gi:3429390 /DB_XREF=est:oy81f08.s1 /CLONE=IMAGE:1672263 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1 AI090331 protein phosphatase 1, regulatory (inhibitor) subunit 7 PPP1R7 5510 NM_002712 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201214_s_at NM_002712 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002712.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 7 (PPP1R7), mRNA. /FEA=mRNA /GEN=PPP1R7 /PROD=protein phosphatase 1, regulatory subunit 7 /DB_XREF=gi:4506012 /UG=Hs.36587 protein phosphatase 1, regulatory subunit 7 /FL=gb:BC000910.1 gb:NM_002712.1 NM_002712 protein phosphatase 1, regulatory (inhibitor) subunit 7 PPP1R7 5510 NM_002712 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008599 // protein phosphatase type 1 regulator activity // traceable author statement /// 0030234 // enzyme regulator activity // non-traceable author statement 201215_at NM_005032 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005032.2 /DEF=Homo sapiens plastin 3 (T isoform) (PLS3), mRNA. /FEA=mRNA /GEN=PLS3 /PROD=plastin 3 precursor /DB_XREF=gi:7549808 /UG=Hs.4114 plastin 3 (T isoform) /FL=gb:M22299.1 gb:NM_005032.2 NM_005032 plastin 3 (T isoform) PLS3 5358 NM_001136025 /// NM_005032 0007015 // actin filament organization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201216_at NM_006817 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006817.2 /DEF=Homo sapiens endoplasmic reticulum lumenal protein (ERP28), mRNA. /FEA=mRNA /GEN=ERP28 /PROD=endoplasmic reticulum lumenal protein ERp28precursor /DB_XREF=gi:13124889 /UG=Hs.75841 endoplasmic reticulum lumenal protein /FL=gb:NM_006817.2 NM_006817 endoplasmic reticulum protein 29 ERP29 10961 NM_001034025 /// NM_006817 0006457 // protein folding // traceable author statement /// 0006886 // intracellular protein transport // traceable author statement /// 0009306 // protein secretion // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003756 // protein disulfide isomerase activity // traceable author statement 201217_x_at NM_000967 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000967.1 /DEF=Homo sapiens ribosomal protein L3 (RPL3), mRNA. /FEA=mRNA /GEN=RPL3 /PROD=ribosomal protein L3 /DB_XREF=gi:4506648 /UG=Hs.119598 ribosomal protein L3 /FL=gb:BC002408.1 gb:BC004323.1 gb:NM_000967.1 NM_000967 ribosomal protein L3 RPL3 6122 NM_000967 /// NM_001033853 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005730 // nucleolus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0003735 // structural constituent of ribosome // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201218_at N23018 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N23018 /FEA=EST /DB_XREF=gi:1137168 /DB_XREF=est:yx65d12.s1 /CLONE=IMAGE:266615 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 N23018 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001329 /// NM_022802 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201219_at AW269836 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW269836 /FEA=EST /DB_XREF=gi:6656866 /DB_XREF=est:xv45h03.x1 /CLONE=IMAGE:2816117 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 AW269836 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001329 /// NM_022802 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201220_x_at NM_001329 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001329.1 /DEF=Homo sapiens C-terminal binding protein 2 (CTBP2), transcript variant 1, mRNA. /FEA=mRNA /GEN=CTBP2 /PROD=C-terminal binding protein 2, isoform 1 /DB_XREF=gi:4557498 /UG=Hs.171391 C-terminal binding protein 2 /FL=gb:AF016507.1 gb:NM_001329.1 NM_001329 C-terminal binding protein 2 CTBP2 1488 NM_001083914 /// NM_001329 /// NM_022802 0008152 // metabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0019079 // viral genome replication // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201221_s_at NM_003089 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003089.1 /DEF=Homo sapiens small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) (SNRP70), mRNA. /FEA=mRNA /GEN=SNRP70 /PROD=small nuclear ribonucleoprotein 70kD polypeptide(RNP antigen) /DB_XREF=gi:4507118 /UG=Hs.174051 small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen) /FL=gb:BC000342.1 gb:M22636.1 gb:NM_003089.1 NM_003089 small nuclear ribonucleoprotein 70kDa (U1) SNRNP70 6625 NM_003089 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from mutant phenotype /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201222_s_at AL527365 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL527365 /FEA=EST /DB_XREF=gi:12790858 /DB_XREF=est:AL527365 /CLONE=CS0DC021YG08 (5 prime) /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1 AL527365 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_002874 0000718 // nucleotide-excision repair, DNA damage removal // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201223_s_at NM_002874 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002874.1 /DEF=Homo sapiens RAD23 (S. cerevisiae) homolog B (RAD23B), mRNA. /FEA=mRNA /GEN=RAD23B /PROD=RAD23 (S. cerevisiae) homolog B /DB_XREF=gi:4506386 /UG=Hs.178658 RAD23 (S. cerevisiae) homolog B /FL=gb:NM_002874.1 gb:D21090.1 NM_002874 RAD23 homolog B (S. cerevisiae) RAD23B 5887 NM_002874 0000718 // nucleotide-excision repair, DNA damage removal // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // inferred from electronic annotation /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0003684 // damaged DNA binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201224_s_at AU147713 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU147713 /FEA=EST /DB_XREF=gi:11009234 /DB_XREF=est:AU147713 /CLONE=MAMMA1001474 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1 AU147713 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 201225_s_at NM_005839 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005839.1 /DEF=Homo sapiens SerArg-related nuclear matrix protein (plenty of prolines 101-like) (SRM160), mRNA. /FEA=mRNA /GEN=SRM160 /PROD=SerArg-related nuclear matrix protein (plentyof prolines 101-like) /DB_XREF=gi:5032118 /UG=Hs.18192 SerArg-related nuclear matrix protein (plenty of prolines 101-like) /FL=gb:AF048977.1 gb:NM_005839.1 NM_005839 serine/arginine repetitive matrix 1 SRRM1 10250 NM_005839 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 201226_at NM_005004 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1 NM_005004 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa /// SEC31 homolog B (S. cerevisiae) NDUFB8 /// SEC31B 25956 /// 4714 NM_005004 /// NM_015490 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201227_s_at NM_005004 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005004.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) (NDUFB8), mRNA. /FEA=mRNA /GEN=NDUFB8 /PROD=NADH dehydrogenase (ubiquinone) 1 betasubcomplex, 8 (19kD, ASHI) /DB_XREF=gi:4826853 /UG=Hs.198273 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD, ASHI) /FL=gb:BC000466.1 gb:AF044958.1 gb:AF077028.1 gb:NM_005004.1 gb:AL080056.1 NM_005004 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa NDUFB8 4714 NM_005004 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006120 // mitochondrial electron transport, NADH to ubiquinone // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005747 // mitochondrial respiratory chain complex I // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201228_s_at AW074830 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW074830 /FEA=EST /DB_XREF=gi:6029828 /DB_XREF=est:xa08a08.x1 /CLONE=IMAGE:2567702 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 AW074830 ariadne homolog 2 (Drosophila) ARIH2 10425 NM_006321 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201229_s_at BC000422 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000422.1 /DEF=Homo sapiens, ariadne (Drosophila) homolog 2, clone MGC:8671, mRNA, complete cds. /FEA=mRNA /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:12653306 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 BC000422 ariadne homolog 2 (Drosophila) ARIH2 10425 NM_006321 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201230_s_at NM_006321 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006321.1 /DEF=Homo sapiens ariadne (Drosophila) homolog 2 (ARIH2), mRNA. /FEA=mRNA /GEN=ARIH2 /PROD=ariadne (Drosophila) homolog 2 /DB_XREF=gi:5453556 /UG=Hs.241558 ariadne (Drosophila) homolog 2 /FL=gb:BC000422.1 gb:AF099149.1 gb:NM_006321.1 gb:AF183427.1 NM_006321 ariadne homolog 2 (Drosophila) ARIH2 10425 NM_006321 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201231_s_at NM_001428 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001428.1 /DEF=Homo sapiens enolase 1, (alpha) (ENO1), mRNA. /FEA=mRNA /GEN=ENO1 /PROD=enolase 1, (alpha) /DB_XREF=gi:4503570 /UG=Hs.254105 enolase 1, (alpha) /FL=gb:BC001810.1 gb:BC004458.1 gb:M14328.1 gb:NM_001428.1 NM_001428 enolase 1, (alpha) ENO1 2023 NM_001428 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006096 // glycolysis // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from direct assay /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201232_s_at NM_002817 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1 NM_002817 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 PSMD13 5719 NM_002817 /// NM_175932 0007127 // meiosis I // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201233_at NM_002817 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002817.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 (PSMD13), mRNA. /FEA=mRNA /GEN=PSMD13 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 13 /DB_XREF=gi:4506222 /UG=Hs.279554 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 /FL=gb:BC001100.1 gb:BC001747.1 gb:AB009398.1 gb:NM_002817.1 gb:AF083245.1 gb:AF107837.1 NM_002817 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 PSMD13 5719 NM_002817 /// NM_175932 0007127 // meiosis I // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0005838 // proteasome regulatory particle // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201234_at NM_004517 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004517.1 /DEF=Homo sapiens integrin-linked kinase (ILK), mRNA. /FEA=mRNA /GEN=ILK /PROD=integrin-linked kinase /DB_XREF=gi:4758605 /UG=Hs.6196 integrin-linked kinase /FL=gb:U40282.1 gb:NM_004517.1 NM_004517 integrin-linked kinase ILK 3611 NM_001014794 /// NM_001014795 /// NM_004517 0001658 // ureteric bud branching // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // inferred from direct assay /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // non-traceable author statement /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // non-traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // traceable author statement /// 0008283 // cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0009966 // regulation of signal transduction // inferred from electronic annotation /// 0045197 // establishment or maintenance of epithelial cell apical/basal polarity // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from direct assay /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201235_s_at BG339064 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG339064 /FEA=EST /DB_XREF=gi:13145502 /DB_XREF=est:602436889F1 /CLONE=IMAGE:4554551 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1 BG339064 BTG family, member 2 BTG2 7832 NM_006763 0006281 // DNA repair // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006479 // protein amino acid methylation // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201236_s_at NM_006763 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006763.1 /DEF=Homo sapiens BTG family, member 2 (BTG2), mRNA. /FEA=mRNA /GEN=BTG2 /PROD=BTG family, member 2 /DB_XREF=gi:5802987 /UG=Hs.75462 BTG family, member 2 /FL=gb:U72649.1 gb:NM_006763.1 NM_006763 BTG family, member 2 BTG2 7832 NM_006763 0006281 // DNA repair // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006479 // protein amino acid methylation // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation /// 0030182 // neuron differentiation // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201237_at AV685920 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV685920 /FEA=EST /DB_XREF=gi:10287783 /DB_XREF=est:AV685920 /CLONE=GKCEGD05 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1 AV685920 capping protein (actin filament) muscle Z-line, alpha 2 CAPZA2 830 NM_006136 0001764 // neuron migration // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone stimulus // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0046777 // protein amino acid autophosphorylation // inferred from electronic annotation /// 0046785 // microtubule polymerization // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005624 // membrane fraction // inferred from electronic annotation /// 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019861 // flagellum // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation 201238_s_at BC005338 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC005338.1 /DEF=Homo sapiens, capping protein (actin filament) muscle Z-line, alpha 2, clone MGC:12426, mRNA, complete cds. /FEA=mRNA /PROD=capping protein (actin filament) muscle Z-line,alpha 2 /DB_XREF=gi:13529130 /UG=Hs.75546 capping protein (actin filament) muscle Z-line, alpha 2 /FL=gb:BC005338.1 gb:NM_006136.1 gb:U03269.1 BC005338 capping protein (actin filament) muscle Z-line, alpha 2 CAPZA2 830 NM_006136 0001764 // neuron migration // inferred from electronic annotation /// 0001937 // negative regulation of endothelial cell proliferation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0007268 // synaptic transmission // inferred from electronic annotation /// 0007420 // brain development // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030317 // sperm motility // inferred from electronic annotation /// 0030321 // transepithelial chloride transport // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0031116 // positive regulation of microtubule polymerization // inferred from electronic annotation /// 0042311 // vasodilation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone stimulus // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from electronic annotation /// 0046777 // protein amino acid autophosphorylation // inferred from electronic annotation /// 0046785 // microtubule polymerization // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005624 // membrane fraction // inferred from electronic annotation /// 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // traceable author statement /// 0008290 // F-actin capping protein complex // inferred from electronic annotation /// 0009925 // basal plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0019861 // flagellum // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0019900 // kinase binding // inferred from electronic annotation /// 0019905 // syntaxin binding // inferred from electronic annotation /// 0050998 // nitric-oxide synthase binding // inferred from electronic annotation 201239_s_at BF530535 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF530535 /FEA=EST /DB_XREF=gi:11617898 /DB_XREF=est:602071788F1 /CLONE=IMAGE:4214660 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1 BF530535 signal peptidase complex subunit 2 homolog pseudogene /// signal peptidase complex subunit 2 homolog (S. cerevisiae) LOC653566 /// SPCS2 653566 /// 9789 NM_014752 0006465 // signal peptide processing // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201240_s_at NM_014752 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014752.1 /DEF=Homo sapiens KIAA0102 gene product (KIAA0102), mRNA. /FEA=mRNA /GEN=KIAA0102 /PROD=KIAA0102 gene product /DB_XREF=gi:7661907 /UG=Hs.77665 KIAA0102 gene product /FL=gb:D14658.1 gb:NM_014752.1 NM_014752 signal peptidase complex subunit 2 homolog pseudogene /// signal peptidase complex subunit 2 homolog (S. cerevisiae) LOC653566 /// SPCS2 653566 /// 9789 NM_014752 0006465 // signal peptide processing // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005787 // signal peptidase complex // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201241_at NM_004939 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004939.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 (DDX1), mRNA. /FEA=mRNA /GEN=DDX1 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /DB_XREF=gi:4826685 /UG=Hs.78580 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 1 /FL=gb:X70649.1 gb:NM_004939.1 NM_004939 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 DDX1 1653 NM_004939 0000245 // spliceosome assembly // non-traceable author statement /// 0006446 // regulation of translational initiation // non-traceable author statement /// 0007275 // multicellular organismal development // inferred from expression pattern 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // non-traceable author statement /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201242_s_at BC000006 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000006.1 /DEF=Homo sapiens, ATPase, Na+K+ transporting, beta 1 polypeptide, clone MGC:1798, mRNA, complete cds. /FEA=mRNA /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:12652534 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1 BC000006 ATPase, Na+/K+ transporting, beta 1 polypeptide ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005890 // sodium:potassium-exchanging ATPase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005391 // sodium:potassium-exchanging ATPase activity // traceable author statement /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation 201243_s_at NM_001677 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001677.1 /DEF=Homo sapiens ATPase, Na+K+ transporting, beta 1 polypeptide (ATP1B1), mRNA. /FEA=mRNA /GEN=ATP1B1 /PROD=ATPase, Na+K+ transporting, beta 1 polypeptide /DB_XREF=gi:4502276 /UG=Hs.78629 ATPase, Na+K+ transporting, beta 1 polypeptide /FL=gb:BC000006.1 gb:NM_001677.1 NM_001677 ATPase, Na+/K+ transporting, beta 1 polypeptide ATP1B1 481 NM_001001787 /// NM_001677 0001666 // response to hypoxia // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006813 // potassium ion transport // inferred from electronic annotation /// 0006814 // sodium ion transport // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005890 // sodium:potassium-exchanging ATPase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0005391 // sodium:potassium-exchanging ATPase activity // traceable author statement /// 0005391 // sodium:potassium-exchanging ATPase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0031402 // sodium ion binding // inferred from electronic annotation 201244_s_at NM_002880 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002880.1 /DEF=Homo sapiens v-raf-1 murine leukemia viral oncogene homolog 1 (RAF1), mRNA. /FEA=mRNA /GEN=RAF1 /PROD=v-raf-1 murine leukemia viral oncogene homolog1 /DB_XREF=gi:4506400 /UG=Hs.85181 v-raf-1 murine leukemia viral oncogene homolog 1 /FL=gb:NM_002880.1 NM_002880 v-raf-1 murine leukemia viral oncogene homolog 1 RAF1 5894 NM_002880 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006915 // apoptosis // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0007010 // cytoskeleton organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // not recorded /// 0008283 // cell proliferation // traceable author statement /// 0048011 // nerve growth factor receptor signaling pathway // inferred from electronic annotation 0005741 // mitochondrial outer membrane // traceable author statement /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0005057 // receptor signaling protein activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0019992 // diacylglycerol binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201245_s_at AL523776 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL523776 /FEA=EST /DB_XREF=gi:12787269 /DB_XREF=est:AL523776 /CLONE=CS0DC003YC23 (5 prime) /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1 AL523776 OTU domain, ubiquitin aldehyde binding 1 OTUB1 55611 NM_017670 /// NR_003089 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201246_s_at NM_017670 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_017670.1 /DEF=Homo sapiens hypothetical protein FLJ20113 (FLJ20113), mRNA. /FEA=mRNA /GEN=FLJ20113 /PROD=hypothetical protein FLJ20113 /DB_XREF=gi:8923113 /UG=Hs.108504 hypothetical protein FLJ20113 /FL=gb:NM_017670.1 NM_017670 OTU domain, ubiquitin aldehyde binding 1 OTUB1 55611 NM_017670 /// NR_003089 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201247_at BE513151 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE513151 /FEA=EST /DB_XREF=gi:9720362 /DB_XREF=est:601171940F1 /CLONE=IMAGE:3545697 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1 BE513151 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030528 // transcription regulator activity // inferred from electronic annotation 201248_s_at NM_004599 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004599.1 /DEF=Homo sapiens sterol regulatory element binding transcription factor 2 (SREBF2), mRNA. /FEA=mRNA /GEN=SREBF2 /PROD=sterol regulatory element binding transcriptionfactor 2 /DB_XREF=gi:4759169 /UG=Hs.108689 sterol regulatory element binding transcription factor 2 /FL=gb:U02031.1 gb:NM_004599.1 NM_004599 sterol regulatory element binding transcription factor 2 SREBF2 6721 NM_004599 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006629 // lipid metabolic process // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030528 // transcription regulator activity // inferred from electronic annotation 201249_at AI091047 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI091047 /FEA=EST /DB_XREF=gi:3430106 /DB_XREF=est:qa53b03.s1 /CLONE=IMAGE:1690445 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1 AI091047 solute carrier family 2 (facilitated glucose transporter), member 1 SLC2A1 6513 NM_006516 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005624 // membrane fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005351 // sugar:hydrogen symporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 201250_s_at NM_006516 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006516.1 /DEF=Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1), mRNA. /FEA=mRNA /GEN=SLC2A1 /PROD=solute carrier family 2 (facilitated glucosetransporter), member 1 /DB_XREF=gi:5730050 /UG=Hs.169902 solute carrier family 2 (facilitated glucose transporter), member 1 /FL=gb:K03195.1 gb:NM_006516.1 NM_006516 solute carrier family 2 (facilitated glucose transporter), member 1 SLC2A1 6513 NM_006516 0006810 // transport // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005624 // membrane fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation /// 0005351 // sugar:hydrogen symporter activity // inferred from electronic annotation /// 0005355 // glucose transmembrane transporter activity // traceable author statement /// 0005355 // glucose transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0022891 // substrate-specific transmembrane transporter activity // inferred from electronic annotation 201251_at NM_002654 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002654.1 /DEF=Homo sapiens pyruvate kinase, muscle (PKM2), mRNA. /FEA=mRNA /GEN=PKM2 /PROD=pyruvate kinase, muscle /DB_XREF=gi:4505838 /UG=Hs.198281 pyruvate kinase, muscle /FL=gb:BC000481.1 gb:M23725.1 gb:M26252.1 gb:NM_002654.1 NM_002654 pyruvate kinase, muscle PKM2 5315 NM_002654 /// NM_182470 /// NM_182471 0006096 // glycolysis // inferred from electronic annotation /// 0006096 // glycolysis // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // non-traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // not recorded /// 0004743 // pyruvate kinase activity // inferred from electronic annotation /// 0004743 // pyruvate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030955 // potassium ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201252_at NM_006503 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006503.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 4 (PSMC4), mRNA. /FEA=mRNA /GEN=PSMC4 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 4 /DB_XREF=gi:5729990 /UG=Hs.211594 proteasome (prosome, macropain) 26S subunit, ATPase, 4 /FL=gb:BC000343.1 gb:AF038965.1 gb:AF020736.1 gb:U27515.1 gb:NM_006503.1 NM_006503 proteasome (prosome, macropain) 26S subunit, ATPase, 4 PSMC4 5704 NM_006503 /// NM_153001 0001824 // blastocyst development // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201253_s_at NM_006319 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006319.1 /DEF=Homo sapiens CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) (CDIPT), mRNA. /FEA=mRNA /GEN=CDIPT /PROD=CDP-diacylglycerol--inositol3-phosphatidyltransferase (phosphatidylinositol synthase) /DB_XREF=gi:5453905 /UG=Hs.227107 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) /FL=gb:BC001444.1 gb:AF014807.1 gb:NM_006319.1 NM_006319 CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) CDIPT 10423 NM_006319 0008654 // phospholipid biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003881 // CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity // inferred from electronic annotation /// 0008526 // phosphatidylinositol transporter activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016780 // phosphotransferase activity, for other substituted phosphate groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation 201254_x_at NM_001010 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001010.1 /DEF=Homo sapiens ribosomal protein S6 (RPS6), mRNA. /FEA=mRNA /GEN=RPS6 /PROD=ribosomal protein S6 /DB_XREF=gi:4506730 /UG=Hs.241507 ribosomal protein S6 /FL=gb:M20020.1 gb:NM_001010.1 NM_001010 ribosomal protein S6 RPS6 6194 NM_001010 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded /// 0031929 // TOR signaling pathway // inferred from direct assay /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptosis // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201255_x_at NM_004639 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004639.1 /DEF=Homo sapiens HLA-B associated transcript-3 (D6S52E), mRNA. /FEA=mRNA /GEN=D6S52E /PROD=HLA-B associated transcript-3 /DB_XREF=gi:4758109 /UG=Hs.274348 HLA-B associated transcript-3 /FL=gb:M33519.1 gb:NM_004639.1 NM_004639 HLA-B associated transcript 3 BAT3 7917 NM_001098534 /// NM_004639 /// NM_080702 /// NM_080703 0006464 // protein modification process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201256_at NM_004718 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004718.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), mRNA. /FEA=mRNA /GEN=COX7A2L /PROD=cytochrome c oxidase subunit VIIa polypeptide 2like /DB_XREF=gi:4758041 /UG=Hs.30888 cytochrome c oxidase subunit VIIa polypeptide 2 like /FL=gb:BC005251.1 gb:AB007618.1 gb:NM_004718.1 NM_004718 cytochrome c oxidase subunit VIIa polypeptide 2 like COX7A2L 9167 NM_004718 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // traceable author statement /// 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201257_x_at NM_001006 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001006.1 /DEF=Homo sapiens ribosomal protein S3A (RPS3A), mRNA. /FEA=mRNA /GEN=RPS3A /PROD=ribosomal protein S3A /DB_XREF=gi:4506722 /UG=Hs.77039 ribosomal protein S3A /FL=gb:BC000204.1 gb:BC001708.1 gb:BC004981.1 gb:M84711.1 gb:M77234.1 gb:L13802.1 gb:NM_001006.1 NM_001006 ribosomal protein S3A RPS3A 6189 NM_001006 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // inferred from mutant phenotype /// 0006412 // translation // non-traceable author statement /// 0006413 // translational initiation // traceable author statement /// 0006414 // translational elongation // not recorded /// 0006917 // induction of apoptosis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity 201258_at NM_001020 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001020.1 /DEF=Homo sapiens ribosomal protein S16 (RPS16), mRNA. /FEA=mRNA /GEN=RPS16 /PROD=ribosomal protein S16 /DB_XREF=gi:4506690 /UG=Hs.80617 ribosomal protein S16 /FL=gb:BC004324.1 gb:M60854.1 gb:NM_001020.1 NM_001020 ribosomal protein S16 RPS16 6217 NM_001020 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006412 // translation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0015935 // small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0022627 // cytosolic small ribosomal subunit // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201259_s_at AI768845 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI768845 /FEA=EST /DB_XREF=gi:5235354 /DB_XREF=est:wj12e10.x1 /CLONE=IMAGE:2402634 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1 AI768845 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral to plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 201260_s_at NM_006754 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006754.1 /DEF=Homo sapiens synaptophysin-like protein (SYPL), mRNA. /FEA=mRNA /GEN=SYPL /PROD=synaptophysin-like protein /DB_XREF=gi:5803184 /UG=Hs.80919 synaptophysin-like protein /FL=gb:NM_006754.1 NM_006754 synaptophysin-like 1 SYPL1 6856 NM_006754 /// NM_182715 0006810 // transport // inferred from electronic annotation /// 0007268 // synaptic transmission // traceable author statement 0005887 // integral to plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0005215 // transporter activity // inferred from electronic annotation 201261_x_at BC002416 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002416.1 /DEF=Homo sapiens, biglycan, clone MGC:2298, mRNA, complete cds. /FEA=mRNA /PROD=biglycan /DB_XREF=gi:12803216 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1 BC002416 biglycan BGN 633 NM_001711 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201262_s_at NM_001711 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001711.1 /DEF=Homo sapiens biglycan (BGN), mRNA. /FEA=mRNA /GEN=BGN /PROD=biglycan /DB_XREF=gi:4502402 /UG=Hs.821 biglycan /FL=gb:BC002416.1 gb:BC004244.1 gb:J04599.1 gb:NM_001711.1 NM_001711 biglycan BGN 633 NM_001711 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0030133 // transport vesicle // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201263_at NM_003191 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003191.1 /DEF=Homo sapiens threonyl-tRNA synthetase (TARS), mRNA. /FEA=mRNA /GEN=TARS /PROD=threonyl-tRNA synthetase /DB_XREF=gi:4507366 /UG=Hs.84131 threonyl-tRNA synthetase /FL=gb:BC000517.1 gb:M63180.1 gb:NM_003191.1 NM_003191 threonyl-tRNA synthetase TARS 6897 NM_152295 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006435 // threonyl-tRNA aminoacylation // non-traceable author statement /// 0006435 // threonyl-tRNA aminoacylation // inferred from electronic annotation /// 0043039 // tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004829 // threonine-tRNA ligase activity // non-traceable author statement /// 0004829 // threonine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016876 // ligase activity, forming aminoacyl-tRNA and related compounds // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement 201264_at NM_007263 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007263.1 /DEF=Homo sapiens coatomer protein complex, subunit epsilon (COPE), mRNA. /FEA=mRNA /GEN=COPE /PROD=coatomer protein complex, subunit epsilon /DB_XREF=gi:6005734 /UG=Hs.10326 coatomer protein complex, subunit epsilon /FL=gb:AL136928.1 gb:BC003155.1 gb:NM_007263.1 NM_007263 coatomer protein complex, subunit epsilon COPE 11316 NM_007263 /// NM_199442 /// NM_199444 0006810 // transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from electronic annotation /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0016020 // membrane // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030126 // COPI vesicle coat // inferred from electronic annotation /// 0030137 // COPI-coated vesicle // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201265_at AF119897 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF119897.1 /DEF=Homo sapiens PRO2760 mRNA, complete cds. /FEA=mRNA /PROD=PRO2760 /DB_XREF=gi:7770230 /UG=Hs.111334 ferritin, light polypeptide /FL=gb:BC004245.1 gb:M11147.1 gb:M10119.1 gb:NM_000146.1 gb:AF119897.1 AF119897 201266_at NM_003330 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003330.1 /DEF=Homo sapiens thioredoxin reductase 1 (TXNRD1), mRNA. /FEA=mRNA /GEN=TXNRD1 /PROD=thioredoxin reductase 1 /DB_XREF=gi:4507746 /UG=Hs.13046 thioredoxin reductase 1 /FL=gb:D88687.1 gb:AF077367.1 gb:NM_003330.1 gb:AF208018.1 NM_003330 thioredoxin reductase 1 TXNRD1 7296 NM_001093771 /// NM_003330 /// NM_182729 /// NM_182742 /// NM_182743 0001707 // mesoderm formation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007369 // gastrulation // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0004791 // thioredoxin-disulfide reductase activity // not recorded /// 0004791 // thioredoxin-disulfide reductase activity // traceable author statement /// 0004791 // thioredoxin-disulfide reductase activity // inferred from electronic annotation /// 0008430 // selenium binding // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0015035 // protein disulfide oxidoreductase activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016654 // oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor // inferred from electronic annotation /// 0050660 // FAD binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from electronic annotation 201267_s_at AL545523 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL545523 /FEA=EST /DB_XREF=gi:12878005 /DB_XREF=est:AL545523 /CLONE=CS0DI015YE19 (5 prime) /UG=Hs.250758 proteasome (prosome, macropain) 26S subunit, ATPase, 3 /FL=gb:M34079.1 gb:NM_002804.1 AL545523 proteasome (prosome, macropain) 26S subunit, ATPase, 3 PSMC3 5702 NM_002804 0001824 // blastocyst development // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201268_at NM_002512 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002512.1 /DEF=Homo sapiens non-metastatic cells 2, protein (NM23B) expressed in (NME2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NME2 /PROD=non-metastatic cells 2, protein (NM23B)expressed in /DB_XREF=gi:4505408 /UG=Hs.275163 non-metastatic cells 2, protein (NM23B) expressed in /FL=gb:BC002476.1 gb:M36981.1 gb:L16785.1 gb:NM_002512.1 NM_002512 non-metastatic cells 1, protein (NM23A) expressed in /// NME1-NME2 readthrough transcript /// non-metastatic cells 2, protein (NM23B) expressed in NME1 /// NME1-NME2 /// NME2 4830 /// 4831 /// 654364 NM_000269 /// NM_001018136 /// NM_001018137 /// NM_001018138 /// NM_001018139 /// NM_002512 /// NM_198175 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // non-traceable author statement /// 0042981 // regulation of apoptosis // traceable author statement /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201269_s_at AB028991 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB028991.1 /DEF=Homo sapiens mRNA for KIAA1068 protein, partial cds. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:5689472 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1 AB028991 NudC domain containing 3 NUDCD3 23386 NM_015332 201270_x_at NM_015332 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015332.1 /DEF=Homo sapiens KIAA1068 protein (KIAA1068), mRNA. /FEA=mRNA /GEN=KIAA1068 /PROD=KIAA1068 protein /DB_XREF=gi:13357209 /UG=Hs.4770 KIAA1068 protein /FL=gb:BC003691.1 gb:NM_015332.1 NM_015332 NudC domain containing 3 NUDCD3 23386 NM_015332 201271_s_at NM_016732 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016732.1 /DEF=Homo sapiens RNA-binding protein (autoantigenic) (RALY), transcript variant 1, mRNA. /FEA=mRNA /GEN=RALY /PROD=RNA-binding protein (autoantigenic) longisoform /DB_XREF=gi:8051630 /UG=Hs.74111 RNA-binding protein (autoantigenic) /FL=gb:AF148457.1 gb:NM_016732.1 NM_016732 RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) RALY 22913 NM_007367 /// NM_016732 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201272_at NM_001628 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001628.1 /DEF=Homo sapiens aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), mRNA. /FEA=mRNA /GEN=AKR1B1 /PROD=aldo-keto reductase family 1, member B1 (aldosereductase) /DB_XREF=gi:4502048 /UG=Hs.75313 aldo-keto reductase family 1, member B1 (aldose reductase) /FL=gb:BC000260.1 gb:BC005387.1 gb:J04795.1 gb:J05017.1 gb:J05474.1 gb:M34720.1 gb:NM_001628.1 NM_001628 aldo-keto reductase family 1, member B1 (aldose reductase) AKR1B1 231 NM_001628 0005975 // carbohydrate metabolic process // traceable author statement /// 0006950 // response to stress // traceable author statement /// 0055114 // oxidation reduction // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0004032 // aldehyde reductase activity // not recorded /// 0004032 // aldehyde reductase activity // traceable author statement /// 0004032 // aldehyde reductase activity // inferred from electronic annotation /// 0004033 // aldo-keto reductase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201273_s_at NM_003133 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003133.1 /DEF=Homo sapiens signal recognition particle 9kD (SRP9), mRNA. /FEA=mRNA /GEN=SRP9 /PROD=signal recognition particle 9kD /DB_XREF=gi:4507216 /UG=Hs.75975 signal recognition particle 9kD /FL=gb:NM_003133.1 gb:U20998.1 NM_003133 hCG1781062 /// signal recognition particle 9kDa hCG_1781062 /// SRP9 653226 /// 6726 NM_001130440 /// NM_003133 /// XM_001720126 /// XM_927451 /// XM_938116 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0045900 // negative regulation of translational elongation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005785 // signal recognition particle receptor complex // traceable author statement /// 0005786 // signal recognition particle, endoplasmic reticulum targeting // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0048500 // signal recognition particle // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0005047 // signal recognition particle binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation 201274_at NM_002790 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002790.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 5 (PSMA5), mRNA. /FEA=mRNA /GEN=PSMA5 /PROD=proteasome (prosome, macropain) subunit, alphatype, 5 /DB_XREF=gi:4506186 /UG=Hs.76913 proteasome (prosome, macropain) subunit, alpha type, 5 /FL=gb:NM_002790.1 NM_002790 proteasome (prosome, macropain) subunit, alpha type, 5 PSMA5 5686 NM_002790 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201275_at NM_002004 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002004.1 /DEF=Homo sapiens farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) (FDPS), mRNA. /FEA=mRNA /GEN=FDPS /PROD=farnesyl diphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase,geranyltranstransferase) /DB_XREF=gi:4503684 /UG=Hs.77393 farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) /FL=gb:J05262.1 gb:D14697.1 gb:NM_002004.1 NM_002004 farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) FDPS 2224 NM_001135821 /// NM_001135822 /// NM_002004 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // traceable author statement /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0008299 // isoprenoid biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004161 // dimethylallyltranstransferase activity // inferred from electronic annotation /// 0004337 // geranyltranstransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201276_at AF267863 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF267863.1 /DEF=Homo sapiens DC43 mRNA, complete cds. /FEA=mRNA /PROD=DC43 /DB_XREF=gi:12006052 /UG=Hs.77690 RAB5B, member RAS oncogene family /FL=gb:AF267863.1 gb:NM_002868.1 AF267863 RAB5B, member RAS oncogene family RAB5B 5869 NM_002868 0006810 // transport // inferred from electronic annotation /// 0007032 // endosome organization // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030100 // regulation of endocytosis // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005624 // membrane fraction // traceable author statement /// 0005768 // endosome // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0030742 // GTP-dependent protein binding // inferred from direct assay 201277_s_at NM_004499 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004499.1 /DEF=Homo sapiens heterogeneous nuclear ribonucleoprotein AB (HNRPAB), mRNA. /FEA=mRNA /GEN=HNRPAB /PROD=heterogeneous nuclear ribonucleoprotein AB /DB_XREF=gi:4758541 /UG=Hs.81361 heterogeneous nuclear ribonucleoprotein AB /FL=gb:BC002625.1 gb:BC004561.1 gb:M65028.1 gb:NM_004499.1 NM_004499 heterogeneous nuclear ribonucleoprotein A/B HNRNPAB 3182 NM_004499 /// NM_031266 0001837 // epithelial to mesenchymal transition // inferred from sequence or structural similarity /// 0043193 // positive regulation of gene-specific transcription // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003688 // DNA replication origin binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from sequence or structural similarity /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from sequence or structural similarity 201278_at N21202 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N21202 /FEA=EST /DB_XREF=gi:1126372 /DB_XREF=est:yx41e12.s1 /CLONE=IMAGE:264334 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 N21202 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) DAB2 1601 NM_001343 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 201279_s_at BC003064 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003064.1 /DEF=Homo sapiens, disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein), clone MGC:1764, mRNA, complete cds. /FEA=mRNA /PROD=disabled (Drosophila) homolog 2(mitogen-responsive phosphoprotein) /DB_XREF=gi:13111753 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 BC003064 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) DAB2 1601 NM_001343 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 201280_s_at NM_001343 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001343.1 /DEF=Homo sapiens disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) (DAB2), mRNA. /FEA=mRNA /GEN=DAB2 /PROD=disabled (Drosophila) homolog 2 /DB_XREF=gi:4503250 /UG=Hs.81988 disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) /FL=gb:U39050.1 gb:U53446.1 gb:BC003064.1 gb:NM_001343.1 NM_001343 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) DAB2 1601 NM_001343 0000904 // cell morphogenesis involved in differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // inferred from electronic annotation /// 0006907 // pinocytosis // inferred from electronic annotation /// 0007588 // excretion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005905 // coated pit // inferred from direct assay /// 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 201281_at NM_007002 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007002.1 /DEF=Homo sapiens cell membrane glycoprotein, 110000M(r) (surface antigen) (GP110), mRNA. /FEA=mRNA /GEN=GP110 /PROD=cell membrane glycoprotein, 110000M(r) (surfaceantigen) /DB_XREF=gi:5901959 /UG=Hs.90107 cell membrane glycoprotein, 110000M(r) (surface antigen) /FL=gb:NM_007002.1 gb:D64154.1 NM_007002 adhesion regulating molecule 1 ADRM1 11047 NM_007002 /// NM_175573 0006368 // RNA elongation from RNA polymerase II promoter // inferred from mutant phenotype /// 0043248 // proteasome assembly // inferred from direct assay 0000502 // proteasome complex // inferred from direct assay /// 0005624 // membrane fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0008538 // proteasome activator activity // inferred from direct assay 201282_at NM_002541 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002541.1 /DEF=Homo sapiens oxoglutarate dehydrogenase (lipoamide) (OGDH), mRNA. /FEA=mRNA /GEN=OGDH /PROD=oxoglutarate dehydrogenase (lipoamide) /DB_XREF=gi:4505492 /UG=Hs.168669 oxoglutarate dehydrogenase (lipoamide) /FL=gb:BC004964.1 gb:NM_002541.1 gb:D10523.1 NM_002541 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) OGDH 4967 NM_001003941 /// NM_002541 0006091 // generation of precursor metabolites and energy // inferred from sequence or structural similarity /// 0006096 // glycolysis // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from sequence or structural similarity 0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from sequence or structural similarity /// 0004591 // oxoglutarate dehydrogenase (succinyl-transferring) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016624 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor // inferred from electronic annotation /// 0030976 // thiamin pyrophosphate binding // inferred from electronic annotation /// 0050164 // oxoglutarate dehydrogenase (NADP+) activity // inferred from electronic annotation 201283_s_at J03068 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03068.1 /DEF=Human DNF1552 (lung) mRNA, complete cds. /FEA=mRNA /DB_XREF=gi:181629 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2 J03068 trafficking protein, kinesin binding 1 TRAK1 22906 NM_001042646 /// NM_014965 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006493 // protein amino acid O-linked glycosylation // inferred from sequence or structural similarity /// 0006508 // proteolysis // inferred from electronic annotation /// 0006605 // protein targeting // inferred from sequence or structural similarity 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019895 // kinesin-associated mitochondrial adaptor activity // inferred by curator /// 0050811 // GABA receptor binding // inferred from electronic annotation 201284_s_at NM_001640 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001640.2 /DEF=Homo sapiens N-acylaminoacyl-peptide hydrolase (APEH), mRNA. /FEA=mRNA /GEN=APEH /PROD=N-acylaminoacyl-peptide hydrolase /DB_XREF=gi:9951916 /UG=Hs.78223 N-acylaminoacyl-peptide hydrolase /FL=gb:BC000362.1 gb:BC001826.1 gb:J03068.1 gb:D38441.1 gb:AF141383.1 gb:NM_001640.2 NM_001640 N-acylaminoacyl-peptide hydrolase APEH 327 NM_001640 0006508 // proteolysis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004252 // serine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201285_at NM_013446 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013446.1 /DEF=Homo sapiens makorin, ring finger protein, 1 (MKRN1), mRNA. /FEA=mRNA /GEN=MKRN1 /PROD=makorin, ring finger protein, 1 /DB_XREF=gi:7305272 /UG=Hs.7838 makorin, ring finger protein, 1 /FL=gb:AL136812.1 gb:AF192784.1 gb:NM_013446.1 NM_013446 makorin ring finger protein 1 MKRN1 23608 NM_013446 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031965 // nuclear membrane // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201286_at Z48199 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:Z48199 /DEF=H.sapiens syndecan-1 gene (exons 2-5) /FEA=mRNA /DB_XREF=gi:666051 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1 Z48199 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201287_s_at NM_002997 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002997.1 /DEF=Homo sapiens syndecan 1 (SDC1), mRNA. /FEA=mRNA /GEN=SDC1 /PROD=syndecan 1 /DB_XREF=gi:4506858 /UG=Hs.82109 syndecan 1 /FL=gb:J05392.1 gb:NM_002997.1 NM_002997 syndecan 1 SDC1 6382 NM_001006946 /// NM_002997 0005887 // integral to plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201288_at NM_001175 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001175.1 /DEF=Homo sapiens Rho GDP dissociation inhibitor (GDI) beta (ARHGDIB), mRNA. /FEA=mRNA /GEN=ARHGDIB /PROD=Rho GDP dissociation inhibitor (GDI) beta /DB_XREF=gi:10835001 /UG=Hs.83656 Rho GDP dissociation inhibitor (GDI) beta /FL=gb:NM_001175.1 gb:L20688.1 NM_001175 Rho GDP dissociation inhibitor (GDI) beta ARHGDIB 397 NM_001175 0006928 // cell motion // traceable author statement /// 0006955 // immune response // traceable author statement /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0016023 // cytoplasmic membrane-bounded vesicle // traceable author statement 0005094 // Rho GDP-dissociation inhibitor activity // traceable author statement /// 0005094 // Rho GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201289_at NM_001554 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001554.1 /DEF=Homo sapiens cysteine-rich, angiogenic inducer, 61 (CYR61), mRNA. /FEA=mRNA /GEN=CYR61 /PROD=cysteine-rich, angiogenic inducer, 61 /DB_XREF=gi:4504612 /UG=Hs.8867 cysteine-rich, angiogenic inducer, 61 /FL=gb:BC001271.1 gb:U62015.1 gb:AF003594.1 gb:AF031385.1 gb:NM_001554.1 NM_001554 cysteine-rich, angiogenic inducer, 61 CYR61 3491 NM_001554 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005576 // extracellular region // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0008201 // heparin binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201290_at NM_014300 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014300.1 /DEF=Homo sapiens signal peptidase complex (18kD) (SPC18), mRNA. /FEA=mRNA /GEN=SPC18 /PROD=signal peptidase complex (18kD) /DB_XREF=gi:7657608 /UG=Hs.9534 signal peptidase complex (18kD) /FL=gb:BC000359.1 gb:AF061737.1 gb:AF108945.1 gb:NM_014300.1 NM_014300 SEC11 homolog A (S. cerevisiae) SEC11A 23478 NM_014300 0006465 // signal peptide processing // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201291_s_at AU159942 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU159942 /FEA=EST /DB_XREF=gi:11021463 /DB_XREF=est:AU159942 /CLONE=Y79AA1000724 /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AU159942 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006265 // DNA topological change // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from direct assay /// 0006281 // DNA repair // non-traceable author statement /// 0006974 // response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptosis // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of retroviral genome replication // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphoinositide-mediated signaling // non-traceable author statement 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay /// 0003918 // DNA topoisomerase (ATP-hydrolyzing) activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201292_at AL561834 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL561834 /FEA=EST /DB_XREF=gi:12909658 /DB_XREF=est:AL561834 /CLONE=CS0DB005YC15 (3 prime) /UG=Hs.156346 topoisomerase (DNA) II alpha (170kD) /FL=gb:J04088.1 gb:NM_001067.1 AL561834 topoisomerase (DNA) II alpha 170kDa TOP2A 7153 NM_001067 0006259 // DNA metabolic process // inferred from electronic annotation /// 0006260 // DNA replication // non-traceable author statement /// 0006265 // DNA topological change // inferred from electronic annotation /// 0006266 // DNA ligation // inferred from direct assay /// 0006281 // DNA repair // non-traceable author statement /// 0006974 // response to DNA damage stimulus // inferred from direct assay /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0040016 // embryonic cleavage // inferred from electronic annotation /// 0043065 // positive regulation of apoptosis // inferred from direct assay /// 0045070 // positive regulation of viral genome replication // inferred from mutant phenotype /// 0045870 // positive regulation of retroviral genome replication // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048015 // phosphoinositide-mediated signaling // non-traceable author statement 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005694 // chromosome // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005814 // centriole // inferred from direct assay /// 0009330 // DNA topoisomerase complex (ATP-hydrolyzing) // inferred from direct assay /// 0019035 // viral integration complex // non-traceable author statement /// 0043234 // protein complex // inferred from physical interaction 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003682 // chromatin binding // inferred from direct assay /// 0003916 // DNA topoisomerase activity // inferred from electronic annotation /// 0003918 // DNA topoisomerase (ATP-hydrolyzing) activity // inferred from direct assay /// 0003918 // DNA topoisomerase (ATP-hydrolyzing) activity // inferred from electronic annotation /// 0005080 // protein kinase C binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008094 // DNA-dependent ATPase activity // inferred from direct assay /// 0008144 // drug binding // inferred from direct assay /// 0016853 // isomerase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0042826 // histone deacetylase binding // inferred from physical interaction /// 0043130 // ubiquitin binding // inferred from mutant phenotype /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201293_x_at NM_021130 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021130.1 /DEF=Homo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA. /FEA=mRNA /GEN=PPIA /PROD=peptidylprolyl isomerase A (cyclophilin A) /DB_XREF=gi:10863926 /UG=Hs.182937 peptidylprolyl isomerase A (cyclophilin A) /FL=gb:NM_021130.1 gb:BC000689.1 gb:BC005320.1 NM_021130 peptidylprolyl isomerase A (cyclophilin A) PPIA 5478 NM_021130 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0019047 // provirus integration // not recorded /// 0019059 // initiation of viral infection // not recorded /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045069 // regulation of viral genome replication // inferred from mutant phenotype /// 0045069 // regulation of viral genome replication // inferred from sequence or structural similarity /// 0045069 // regulation of viral genome replication // traceable author statement 0005576 // extracellular region // not recorded /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from direct assay 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation /// 0046790 // virion binding // non-traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 201294_s_at N24643 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N24643 /FEA=EST /DB_XREF=gi:1138793 /DB_XREF=est:yx89f11.s1 /CLONE=IMAGE:268941 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 N24643 WD repeat and SOCS box-containing 1 WSB1 26118 NM_015626 /// NM_134265 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201295_s_at BF111821 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF111821 /FEA=EST /DB_XREF=gi:10941511 /DB_XREF=est:7l36a06.x1 /CLONE=IMAGE:3523474 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 BF111821 WD repeat and SOCS box-containing 1 WSB1 26118 NM_015626 /// NM_134265 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201296_s_at NM_015626 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015626.1 /DEF=Homo sapiens DKFZP564A122 protein (DKFZP564A122), mRNA. /FEA=mRNA /GEN=DKFZP564A122 /PROD=DKFZP564A122 protein /DB_XREF=gi:7661595 /UG=Hs.187991 DKFZP564A122 protein /FL=gb:AF106684.1 gb:NM_015626.1 NM_015626 WD repeat and SOCS box-containing 1 WSB1 26118 NM_015626 /// NM_134265 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0016301 // kinase activity // inferred from electronic annotation 201297_s_at AK023321 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK023321.1 /DEF=Homo sapiens cDNA FLJ13259 fis, clone OVARC1000876, moderately similar to MOB1 PROTEIN. /FEA=mRNA /DB_XREF=gi:10435206 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 AK023321 MOB1, Mps One Binder kinase activator-like 1B (yeast) MOBKL1B 55233 NM_018221 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201298_s_at BC003398 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003398.1 /DEF=Homo sapiens, hypothetical protein FLJ10788, clone MGC:4929, mRNA, complete cds. /FEA=mRNA /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:13097287 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 BC003398 MOB1, Mps One Binder kinase activator-like 1B (yeast) MOBKL1B 55233 NM_018221 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201299_s_at NM_018221 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018221.1 /DEF=Homo sapiens hypothetical protein FLJ10788 (FLJ10788), mRNA. /FEA=mRNA /GEN=FLJ10788 /PROD=hypothetical protein FLJ10788 /DB_XREF=gi:8922670 /UG=Hs.196437 hypothetical protein FLJ10788 /FL=gb:AB016839.1 gb:BC003398.1 gb:NM_018221.1 NM_018221 MOB1, Mps One Binder kinase activator-like 1B (yeast) MOBKL1B 55233 NM_018221 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201300_s_at NM_000311 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000311.1 /DEF=Homo sapiens prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) (PRNP), mRNA. /FEA=mRNA /GEN=PRNP /PROD=prion protein /DB_XREF=gi:4506112 /UG=Hs.74621 prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) /FL=gb:AY008282.1 gb:M13899.1 gb:NM_000311.1 NM_000311 prion protein PRNP 5621 NM_000311 /// NM_001080121 /// NM_001080122 /// NM_001080123 /// NM_183079 0006878 // cellular copper ion homeostasis // non-traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from sequence or structural similarity /// 0008152 // metabolic process // traceable author statement /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0051260 // protein homooligomerization // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0019898 // extrinsic to membrane // traceable author statement /// 0031225 // anchored to membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0045121 // membrane raft // inferred from sequence or structural similarity 0005507 // copper ion binding // inferred from electronic annotation /// 0005507 // copper ion binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008017 // microtubule binding // inferred from direct assay /// 0015631 // tubulin binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction 201301_s_at BC000182 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000182.1 /DEF=Homo sapiens, annexin A4, clone MGC:2271, mRNA, complete cds. /FEA=mRNA /PROD=annexin A4 /DB_XREF=gi:12652858 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2 BC000182 annexin A4 ANXA4 307 NM_001153 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement 201302_at NM_001153 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001153.2 /DEF=Homo sapiens annexin A4 (ANXA4), mRNA. /FEA=mRNA /GEN=ANXA4 /PROD=annexin IV /DB_XREF=gi:4809272 /UG=Hs.77840 annexin A4 /FL=gb:D78152.1 gb:BC000182.1 gb:M82809.1 gb:M19383.1 gb:NM_001153.2 NM_001153 annexin A4 ANXA4 307 NM_001153 0006916 // anti-apoptosis // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0050819 // negative regulation of coagulation // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay 0004859 // phospholipase inhibitor activity // non-traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // non-traceable author statement /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // non-traceable author statement 201303_at NM_014740 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014740.1 /DEF=Homo sapiens KIAA0111 gene product (KIAA0111), mRNA. /FEA=mRNA /GEN=KIAA0111 /PROD=KIAA0111 gene product /DB_XREF=gi:7661919 /UG=Hs.79768 KIAA0111 gene product /FL=gb:BC003662.1 gb:BC004386.1 gb:D21853.1 gb:NM_014740.1 NM_014740 eukaryotic translation initiation factor 4A, isoform 3 EIF4A3 9775 NM_014740 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0017148 // negative regulation of translation // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // inferred from direct assay /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008143 // poly(A) binding // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation 201304_at NM_005000 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005000.2 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) (NDUFA5), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=NDUFA5 /PROD=NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 5 /DB_XREF=gi:13699821 /UG=Hs.83916 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) /FL=gb:BC000813.1 gb:NM_005000.2 gb:U53468.1 gb:U64028.1 NM_005000 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa NDUFA5 4698 NM_005000 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0022904 // respiratory electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // traceable author statement /// 0016651 // oxidoreductase activity, acting on NADH or NADPH // inferred from electronic annotation 201305_x_at AV712577 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV712577 /FEA=EST /DB_XREF=gi:10731883 /DB_XREF=est:AV712577 /CLONE=DCAAUH03 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1 AV712577 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B ANP32B 10541 NM_006401 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201306_s_at NM_006401 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006401.1 /DEF=Homo sapiens acidic protein rich in leucines (SSP29), mRNA. /FEA=mRNA /GEN=SSP29 /PROD=acidic protein rich in leucines /DB_XREF=gi:5454087 /UG=Hs.84264 acidic protein rich in leucines /FL=gb:U70439.1 gb:NM_006401.1 NM_006401 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B ANP32B 10541 NM_006401 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201307_at AL534972 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL534972 /FEA=EST /DB_XREF=gi:12798465 /DB_XREF=est:AL534972 /CLONE=CS0DF007YI02 (5 prime) /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1 AL534972 septin 11 SEPT11 55752 NM_018243 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 201308_s_at NM_018243 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018243.1 /DEF=Homo sapiens hypothetical protein FLJ10849 (FLJ10849), mRNA. /FEA=mRNA /GEN=FLJ10849 /PROD=hypothetical protein FLJ10849 /DB_XREF=gi:8922711 /UG=Hs.8768 hypothetical protein FLJ10849 /FL=gb:NM_018243.1 NM_018243 septin 11 SEPT11 55752 NM_018243 0007049 // cell cycle // inferred from electronic annotation /// 0051291 // protein heterooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0001725 // stress fiber // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0031105 // septin complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation 201309_x_at U36189 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U36189.1 /DEF=Human p311 protein (hP311) mRNA, complete cds. /FEA=mRNA /GEN=hP311 /PROD=p311 protein /DB_XREF=gi:1244509 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1 U36189 chromosome 5 open reading frame 13 C5orf13 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201310_s_at NM_004772 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004772.1 /DEF=Homo sapiens P311 protein (P311), mRNA. /FEA=mRNA /GEN=P311 /PROD=P311 protein /DB_XREF=gi:4758865 /UG=Hs.142827 P311 protein /FL=gb:U36189.1 gb:NM_004772.1 gb:U30521.1 NM_004772 chromosome 5 open reading frame 13 C5orf13 9315 NM_001142474 /// NM_001142475 /// NM_001142476 /// NM_001142477 /// NM_001142478 /// NM_001142479 /// NM_001142480 /// NM_001142481 /// NM_001142482 /// NM_001142483 /// NM_004772 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201311_s_at AL515318 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL515318 /FEA=EST /DB_XREF=gi:12778811 /DB_XREF=est:AL515318 /CLONE=CL0BB030ZH05 (5 prime) /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1 AL515318 SH3 domain binding glutamic acid-rich protein like SH3BGRL 6451 NM_003022 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201312_s_at NM_003022 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003022.1 /DEF=Homo sapiens SH3 domain binding glutamic acid-rich protein like (SH3BGRL), mRNA. /FEA=mRNA /GEN=SH3BGRL /PROD=SH3 domain binding glutamic acid-rich proteinlike /DB_XREF=gi:4506924 /UG=Hs.14368 SH3 domain binding glutamic acid-rich protein like /FL=gb:AL136718.1 gb:AF042081.1 gb:NM_003022.1 NM_003022 SH3 domain binding glutamic acid-rich protein like SH3BGRL 6451 NM_003022 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0005070 // SH3/SH2 adaptor activity // traceable author statement /// 0017124 // SH3 domain binding // inferred from electronic annotation 201313_at NM_001975 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001975.1 /DEF=Homo sapiens enolase 2, (gamma, neuronal) (ENO2), mRNA. /FEA=mRNA /GEN=ENO2 /PROD=enolase 2, (gamma, neuronal) /DB_XREF=gi:5803010 /UG=Hs.146580 enolase 2, (gamma, neuronal) /FL=gb:BC002745.1 gb:NM_001975.1 gb:M22349.1 NM_001975 enolase 2 (gamma, neuronal) ENO2 2026 NM_001975 0006096 // glycolysis // inferred from electronic annotation 0000015 // phosphopyruvate hydratase complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004634 // phosphopyruvate hydratase activity // traceable author statement /// 0004634 // phosphopyruvate hydratase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201314_at NM_006374 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006374.1 /DEF=Homo sapiens serinethreonine kinase 25 (Ste20, yeast homolog) (STK25), mRNA. /FEA=mRNA /GEN=STK25 /PROD=serinethreonine kinase 25 (Ste20, yeasthomolog) /DB_XREF=gi:5454173 /UG=Hs.155206 serinethreonine kinase 25 (Ste20, yeast homolog) /FL=gb:D63780.1 gb:NM_006374.1 NM_006374 serine/threonine kinase 25 (STE20 homolog, yeast) STK25 10494 NM_006374 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201315_x_at NM_006435 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006435.1 /DEF=Homo sapiens interferon induced transmembrane protein 2 (1-8D) (IFITM2), mRNA. /FEA=mRNA /GEN=IFITM2 /PROD=interferon induced transmembrane protein 2(1-8D) /DB_XREF=gi:10835237 /UG=Hs.174195 interferon induced transmembrane protein 2 (1-8D) /FL=gb:NM_006435.1 NM_006435 interferon induced transmembrane protein 2 (1-8D) IFITM2 10581 NM_006435 0006955 // immune response // traceable author statement /// 0009607 // response to biotic stimulus // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201316_at AL523904 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL523904 /FEA=EST /DB_XREF=gi:12787397 /DB_XREF=est:AL523904 /CLONE=CS0DC003YB07 (3 prime) /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1 AL523904 proteasome (prosome, macropain) subunit, alpha type, 2 PSMA2 5683 NM_002787 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201317_s_at NM_002787 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002787.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2), mRNA. /FEA=mRNA /GEN=PSMA2 /PROD=proteasome (prosome, macropain) subunit, alphatype, 2 /DB_XREF=gi:4506180 /UG=Hs.181309 proteasome (prosome, macropain) subunit, alpha type, 2 /FL=gb:NM_002787.1 NM_002787 proteasome (prosome, macropain) subunit, alpha type, 2 PSMA2 5683 NM_002787 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201318_s_at NM_006471 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1 NM_006471 myosin regulatory light chain MRCL3 /// myosin regulatory light chain MRLC2 MRCL3 /// MRLC2 103910 /// 10627 NM_006471 /// NM_033546 0016459 // myosin complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201319_at NM_006471 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006471.1 /DEF=Homo sapiens myosin, light polypeptide, regulatory, non-sarcomeric (20kD) (MLCB), mRNA. /FEA=mRNA /GEN=MLCB /PROD=myosin, light polypeptide, regulatory,non-sarcomeric (20kD) /DB_XREF=gi:5453739 /UG=Hs.233936 myosin, light polypeptide, regulatory, non-sarcomeric (20kD) /FL=gb:NM_006471.1 NM_006471 myosin regulatory light chain MRCL3 MRCL3 10627 NM_006471 0016459 // myosin complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0003774 // motor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201320_at BF663402 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF663402 /FEA=EST /DB_XREF=gi:11937297 /DB_XREF=est:602144558F1 /CLONE=IMAGE:4297695 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1 BF663402 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 201321_s_at NM_003075 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003075.1 /DEF=Homo sapiens SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 (SMARCC2), mRNA. /FEA=mRNA /GEN=SMARCC2 /PROD=SWISNF related, matrix associated, actindependent regulator of chromatin, subfamily c, member 2 /DB_XREF=gi:4507080 /UG=Hs.236030 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 /FL=gb:U66616.1 gb:NM_003075.1 NM_003075 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 SMARCC2 6601 NM_001130420 /// NM_003075 /// NM_139067 0006333 // chromatin assembly or disassembly // inferred from electronic annotation /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0000785 // chromatin // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0017053 // transcriptional repressor complex // inferred from physical interaction 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction 201322_at NM_001686 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001686.1 /DEF=Homo sapiens ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (ATP5B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=ATP5B /PROD=ATP synthase, H+ transporting, mitochondrial F1complex, beta polypeptide /DB_XREF=gi:4502294 /UG=Hs.25 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide /FL=gb:D00022.1 gb:NM_001686.1 NM_001686 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide ATP5B 506 NM_001686 0001525 // angiogenesis // inferred from mutant phenotype /// 0006091 // generation of precursor metabolites and energy // non-traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from electronic annotation /// 0006754 // ATP biosynthetic process // inferred from mutant phenotype /// 0006754 // ATP biosynthetic process // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006933 // negative regulation of cell adhesion involved in substrate-bound cell migration // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // inferred from mutant phenotype /// 0015992 // proton transport // inferred from electronic annotation /// 0046034 // ATP metabolic process // inferred from electronic annotation /// 0051453 // regulation of intracellular pH // inferred from mutant phenotype 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005753 // mitochondrial proton-transporting ATP synthase complex // inferred from direct assay /// 0005753 // mitochondrial proton-transporting ATP synthase complex // non-traceable author statement /// 0005754 // mitochondrial proton-transporting ATP synthase, catalytic core // non-traceable author statement /// 0005759 // mitochondrial matrix // not recorded /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016469 // proton-transporting two-sector ATPase complex // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0045261 // proton-transporting ATP synthase complex, catalytic core F(1) // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005215 // transporter activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008553 // hydrogen-exporting ATPase activity, phosphorylative mechanism // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016820 // hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042288 // MHC class I protein binding // inferred from direct assay /// 0043499 // eukaryotic cell surface binding // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from mutant phenotype /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201323_at NM_006824 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006824.1 /DEF=Homo sapiens nucleolar protein p40; homolog of yeast EBNA1-binding protein (P40), mRNA. /FEA=mRNA /GEN=P40 /PROD=nucleolar protein p40; homolog of yeastEBNA1-binding protein /DB_XREF=gi:5803110 /UG=Hs.74407 nucleolar protein p40; homolog of yeast EBNA1-binding protein /FL=gb:U86602.1 gb:NM_006824.1 NM_006824 EBNA1 binding protein 2 EBNA1BP2 10969 NM_006824 0042254 // ribosome biogenesis // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201324_at NM_001423 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1 NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 201325_s_at NM_001423 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001423.1 /DEF=Homo sapiens epithelial membrane protein 1 (EMP1), mRNA. /FEA=mRNA /GEN=EMP1 /PROD=epithelial membrane protein 1 /DB_XREF=gi:4503558 /UG=Hs.79368 epithelial membrane protein 1 /FL=gb:U77085.1 gb:U43916.1 gb:NM_001423.1 NM_001423 epithelial membrane protein 1 EMP1 2012 NM_001423 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0008544 // epidermis development // traceable author statement /// 0016049 // cell growth // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 201326_at BE737030 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE737030 /FEA=EST /DB_XREF=gi:10151022 /DB_XREF=est:601304610F1 /CLONE=IMAGE:3639098 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1 BE737030 chaperonin containing TCP1, subunit 6A (zeta 1) CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 201327_s_at NM_001762 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001762.1 /DEF=Homo sapiens chaperonin containing TCP1, subunit 6A (zeta 1) (CCT6A), mRNA. /FEA=mRNA /GEN=CCT6A /PROD=chaperonin containing TCP1, subunit 6A (zeta 1) /DB_XREF=gi:4502642 /UG=Hs.82916 chaperonin containing TCP1, subunit 6A (zeta 1) /FL=gb:M94083.1 gb:NM_001762.1 gb:L27706.1 NM_001762 chaperonin containing TCP1, subunit 6A (zeta 1) CCT6A 908 NM_001009186 /// NM_001762 0006457 // protein folding // traceable author statement /// 0006457 // protein folding // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005832 // chaperonin-containing T-complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 201328_at AL575509 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL575509 /FEA=EST /DB_XREF=gi:12936742 /DB_XREF=est:AL575509 /CLONE=CS0DI059YP21 (3 prime) /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1 AL575509 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) ETS2 2114 NM_005239 0001501 // skeletal system development // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // non-traceable author statement /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201329_s_at NM_005239 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005239.1 /DEF=Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 2 (ETS2), mRNA. /FEA=mRNA /GEN=ETS2 /PROD=v-ets avian erythroblastosis virus E26 oncogenehomolog 2 /DB_XREF=gi:4885220 /UG=Hs.85146 v-ets avian erythroblastosis virus E26 oncogene homolog 2 /FL=gb:J04102.1 gb:NM_005239.1 NM_005239 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) ETS2 2114 NM_005239 0001501 // skeletal system development // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // non-traceable author statement /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201330_at NM_002887 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002887.1 /DEF=Homo sapiens arginyl-tRNA synthetase (RARS), mRNA. /FEA=mRNA /GEN=RARS /PROD=arginyl-tRNA synthetase /DB_XREF=gi:4506428 /UG=Hs.180832 arginyl-tRNA synthetase /FL=gb:BC000528.1 gb:NM_002887.1 NM_002887 arginyl-tRNA synthetase RARS 5917 NM_002887 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006420 // arginyl-tRNA aminoacylation // traceable author statement /// 0006420 // arginyl-tRNA aminoacylation // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004814 // arginine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201331_s_at BC004973 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC004973.1 /DEF=Homo sapiens, signal transducer and activator of transcription 6, interleukin-4 induced, clone MGC:3649, mRNA, complete cds. /FEA=mRNA /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:13436385 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1 BC004973 signal transducer and activator of transcription 6, interleukin-4 induced STAT6 6778 NM_003153 0002829 // negative regulation of T-helper 2 type immune response // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201332_s_at NM_003153 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003153.1 /DEF=Homo sapiens signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), mRNA. /FEA=mRNA /GEN=STAT6 /PROD=signal transducer and activator of transcription6, interleukin-4 induced /DB_XREF=gi:4507258 /UG=Hs.181015 signal transducer and activator of transcription 6, interleukin-4 induced /FL=gb:BC004973.1 gb:NM_003153.1 gb:U16031.1 NM_003153 signal transducer and activator of transcription 6, interleukin-4 induced STAT6 6778 NM_003153 0002829 // negative regulation of T-helper 2 type immune response // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0048295 // positive regulation of isotype switching to IgE isotypes // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201333_s_at AI807672 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI807672 /FEA=EST /DB_XREF=gi:5394238 /DB_XREF=est:wf49f10.x1 /CLONE=IMAGE:2358955 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 AI807672 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_015313 0007186 // G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201334_s_at AB002380 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB002380.1 /DEF=Human mRNA for KIAA0382 gene, partial cds. /FEA=mRNA /GEN=KIAA0382 /DB_XREF=gi:2224704 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 AB002380 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_015313 0007186 // G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201335_s_at NM_015313 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015313.1 /DEF=Homo sapiens KIAA0382 protein; leukemia-associated rho guanine nucleotide exchange factor (GEF) (ARHGEF12), mRNA. /FEA=mRNA /GEN=ARHGEF12 /PROD=KIAA0382 protein; leukemia-associated rhoguanine nucleotide exchange factor (GEF) /DB_XREF=gi:7662087 /UG=Hs.6582 Rho guanine exchange factor (GEF) 12 /FL=gb:AF180681.1 gb:NM_015313.1 NM_015313 Rho guanine nucleotide exchange factor (GEF) 12 ARHGEF12 23365 NM_015313 0007186 // G-protein coupled receptor protein signaling pathway // inferred from direct assay /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0001664 // G-protein-coupled receptor binding // inferred from direct assay /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201336_at BC003570 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003570.1 /DEF=Homo sapiens, Similar to vesicle-associated membrane protein 3, clone MGC:2110, mRNA, complete cds. /FEA=mRNA /PROD=Similar to vesicle-associated membrane protein3 /DB_XREF=gi:13097737 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2 BC003570 vesicle-associated membrane protein 3 (cellubrevin) VAMP3 9341 NM_004781 0006461 // protein complex assembly // traceable author statement /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking during exocytosis // traceable author statement /// 0006944 // membrane fusion // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 201337_s_at NM_004781 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004781.2 /DEF=Homo sapiens vesicle-associated membrane protein 3 (cellubrevin) (VAMP3), mRNA. /FEA=mRNA /GEN=VAMP3 /PROD=vesicle-associated membrane protein 3 /DB_XREF=gi:9257252 /UG=Hs.66708 vesicle-associated membrane protein 3 (cellubrevin) /FL=gb:BC003570.1 gb:NM_004781.2 NM_004781 vesicle-associated membrane protein 3 (cellubrevin) VAMP3 9341 NM_004781 0006461 // protein complex assembly // traceable author statement /// 0006887 // exocytosis // traceable author statement /// 0006904 // vesicle docking during exocytosis // traceable author statement /// 0006944 // membrane fusion // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 201338_x_at NM_002097 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002097.1 /DEF=Homo sapiens general transcription factor IIIA (GTF3A), mRNA. /FEA=mRNA /GEN=GTF3A /PROD=general transcription factor IIIA /DB_XREF=gi:4753158 /UG=Hs.75113 general transcription factor IIIA /FL=gb:D32257.1 gb:NM_002097.1 NM_002097 general transcription factor IIIA GTF3A 2971 NM_002097 /// XM_001715623 /// XM_001716951 /// XM_001717641 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0009303 // rRNA transcription // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003709 // RNA polymerase III transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201339_s_at NM_002979 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002979.1 /DEF=Homo sapiens sterol carrier protein 2 (SCP2), mRNA. /FEA=mRNA /GEN=SCP2 /PROD=sterol carrier protein 2 /DB_XREF=gi:4506822 /UG=Hs.75760 sterol carrier protein 2 /FL=gb:M75883.1 gb:M75884.1 gb:M55421.1 gb:NM_002979.1 NM_002979 sterol carrier protein 2 SCP2 6342 NM_001007098 /// NM_001007099 /// NM_001007100 /// NM_001007250 /// NM_002979 0006694 // steroid biosynthetic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // traceable author statement /// 0005777 // peroxisome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005498 // sterol carrier activity // inferred from electronic annotation /// 0005498 // sterol carrier activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0033814 // propanoyl-CoA C-acyltransferase activity // inferred from electronic annotation 201340_s_at AF010314 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF010314.1 /DEF=Homo sapiens Pig10 (PIG10) mRNA, complete cds. /FEA=mRNA /GEN=PIG10 /PROD=Pig10 /DB_XREF=gi:2415303 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1 AF010314 ectodermal-neural cortex (with BTB-like domain) ENC1 8507 NM_003633 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201341_at NM_003633 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003633.1 /DEF=Homo sapiens ectodermal-neural cortex (with BTB-like domain) (ENC1), mRNA. /FEA=mRNA /GEN=ENC1 /PROD=ectodermal-neural cortex (with BTB-like domain) /DB_XREF=gi:4505460 /UG=Hs.104925 ectodermal-neural cortex (with BTB-like domain) /FL=gb:BC000418.1 gb:AF010314.1 gb:AF059611.1 gb:AF005381.1 gb:NM_003633.1 NM_003633 ectodermal-neural cortex (with BTB-like domain) ENC1 8507 NM_003633 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201342_at NM_003093 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003093.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide C (SNRPC), mRNA. /FEA=mRNA /GEN=SNRPC /PROD=small nuclear ribonucleoprotein polypeptide C /DB_XREF=gi:4507126 /UG=Hs.1063 small nuclear ribonucleoprotein polypeptide C /FL=gb:NM_003093.1 NM_003093 small nuclear ribonucleoprotein polypeptide C SNRPC 6631 NM_003093 0000387 // spliceosomal snRNP biogenesis // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay 0005634 // nucleus // inferred from electronic annotation /// 0005685 // snRNP U1 // inferred from direct assay /// 0015030 // Cajal body // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030619 // U1 snRNA binding // inferred from direct assay /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201343_at BE621259 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE621259 /FEA=EST /DB_XREF=gi:9892197 /DB_XREF=est:601493415F1 /CLONE=IMAGE:3895850 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BE621259 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) UBE2D2 7322 NM_003339 /// NM_181838 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 201344_at BF196642 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF196642 /FEA=EST /DB_XREF=gi:11084786 /DB_XREF=est:7m93c12.x1 /CLONE=IMAGE:3562750 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 BF196642 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) UBE2D2 7322 NM_003339 /// NM_181838 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 201345_s_at NM_003339 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003339.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) (UBE2D2), mRNA. /FEA=mRNA /GEN=UBE2D2 /PROD=ubiquitin-conjugating enzyme E2D 2 (homologousto yeast UBC45) /DB_XREF=gi:4507774 /UG=Hs.108332 ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC45) /FL=gb:U39317.1 gb:NM_003339.1 NM_003339 ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) UBE2D2 7322 NM_003339 /// NM_181838 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation 201346_at NM_024551 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024551.1 /DEF=Homo sapiens hypothetical protein FLJ21432 (FLJ21432), mRNA. /FEA=mRNA /GEN=FLJ21432 /PROD=hypothetical protein FLJ21432 /DB_XREF=gi:13375714 /UG=Hs.11641 hypothetical protein FLJ21432 /FL=gb:NM_024551.1 gb:BC004906.1 NM_024551 adiponectin receptor 2 ADIPOR2 79602 NM_024551 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation /// 0009755 // hormone-mediated signaling // inferred from sequence or structural similarity /// 0019395 // fatty acid oxidation // inferred from sequence or structural similarity /// 0030308 // negative regulation of cell growth // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0042562 // hormone binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from electronic annotation 201347_x_at NM_012203 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012203.1 /DEF=Homo sapiens glyoxylate reductasehydroxypyruvate reductase (GRHPR), mRNA. /FEA=mRNA /GEN=GRHPR /PROD=glyoxylate reductasehydroxypyruvate reductase /DB_XREF=gi:6912395 /UG=Hs.155742 glyoxylate reductasehydroxypyruvate reductase /FL=gb:AF113215.1 gb:BC000605.1 gb:BC003131.1 gb:AF146018.1 gb:AF113251.1 gb:AF134895.1 gb:NM_012203.1 NM_012203 glyoxylate reductase/hydroxypyruvate reductase GRHPR 9380 NM_012203 0007588 // excretion // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0055114 // oxidation reduction // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008465 // glycerate dehydrogenase activity // inferred from direct assay /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0016618 // hydroxypyruvate reductase activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // inferred from direct assay /// 0030267 // glyoxylate reductase (NADP) activity // non-traceable author statement /// 0030267 // glyoxylate reductase (NADP) activity // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation /// 0051287 // NAD binding // traceable author statement 201348_at NM_002084 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002084.2 /DEF=Homo sapiens glutathione peroxidase 3 (plasma) (GPX3), mRNA. /FEA=mRNA /GEN=GPX3 /PROD=plasma glutathione peroxidase 3 precursor /DB_XREF=gi:6006000 /UG=Hs.172153 glutathione peroxidase 3 (plasma) /FL=gb:D00632.1 gb:NM_002084.2 gb:AF217787.1 NM_002084 glutathione peroxidase 3 (plasma) GPX3 2878 NM_002084 0006749 // glutathione metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006982 // response to lipid hydroperoxide // traceable author statement /// 0042744 // hydrogen peroxide catabolic process // traceable author statement /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005625 // soluble fraction // inferred from electronic annotation 0004601 // peroxidase activity // inferred from electronic annotation /// 0004602 // glutathione peroxidase activity // inferred from direct assay /// 0004602 // glutathione peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // traceable author statement /// 0008134 // transcription factor binding // traceable author statement /// 0008430 // selenium binding // inferred from direct assay /// 0008430 // selenium binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0043295 // glutathione binding // inferred from electronic annotation 201349_at NM_004252 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004252.1 /DEF=Homo sapiens solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 (SLC9A3R1), mRNA. /FEA=mRNA /GEN=SLC9A3R1 /PROD=solute carrier family 9 (sodiumhydrogenexchanger), isoform 3 regulatory factor 1 /DB_XREF=gi:4759139 /UG=Hs.184276 solute carrier family 9 (sodiumhydrogen exchanger), isoform 3 regulatory factor 1 /FL=gb:BC001443.1 gb:BC003361.1 gb:AF036241.1 gb:AF015926.1 gb:NM_004252.1 NM_004252 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 SLC9A3R1 9368 NM_004252 0006461 // protein complex assembly // traceable author statement /// 0016055 // Wnt receptor signaling pathway // inferred from electronic annotation /// 0030643 // cellular phosphate ion homeostasis // inferred from electronic annotation /// 0032415 // regulation of sodium:hydrogen antiporter activity // non-traceable author statement 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from physical interaction /// 0031698 // beta-2 adrenergic receptor binding // inferred from physical interaction 201350_at NM_004475 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004475.1 /DEF=Homo sapiens flotillin 2 (FLOT2), mRNA. /FEA=mRNA /GEN=FLOT2 /PROD=flotillin 2 /DB_XREF=gi:4758393 /UG=Hs.184488 flotillin 2 /FL=gb:NM_004475.1 gb:M60922.1 NM_004475 flotillin 2 FLOT2 2319 NM_004475 0007155 // cell adhesion // non-traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement 0005624 // membrane fraction // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005901 // caveola // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201351_s_at AF070656 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF070656.1 /DEF=Homo sapiens FtsH homolog mRNA, complete cds. /FEA=mRNA /PROD=FtsH homolog /DB_XREF=gi:4454687 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1 AF070656 YME1-like 1 (S. cerevisiae) YME1L1 10730 NM_014263 /// NM_139312 0006508 // proteolysis // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201352_at NM_014263 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014263.1 /DEF=Homo sapiens YME1 (S.cerevisiae)-like 1 (YME1L1), mRNA. /FEA=mRNA /GEN=YME1L1 /PROD=YME1 (S.cerevisiae)-like 1 /DB_XREF=gi:7657688 /UG=Hs.206521 YME1 (S.cerevisiae)-like 1 /FL=gb:AF070656.1 gb:NM_014263.1 NM_014263 YME1-like 1 (S. cerevisiae) YME1L1 10730 NM_014263 /// NM_139312 0006508 // proteolysis // inferred from electronic annotation /// 0030163 // protein catabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201353_s_at AI653126 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI653126 /FEA=EST /DB_XREF=gi:4737105 /DB_XREF=est:wb43c08.x1 /CLONE=IMAGE:2308430 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 AI653126 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005731 // nucleolus organizer region // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201354_s_at AA788652 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA788652 /FEA=EST /DB_XREF=gi:2848772 /DB_XREF=est:ah30a09.s1 /CLONE=1240312 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 AA788652 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005731 // nucleolus organizer region // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201355_s_at NM_013449 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013449.1 /DEF=Homo sapiens bromodomain adjacent to zinc finger domain, 2A (BAZ2A), mRNA. /FEA=mRNA /GEN=BAZ2A /PROD=bromodomain adjacent to zinc finger domain, 2A /DB_XREF=gi:7304920 /UG=Hs.277401 bromodomain adjacent to zinc finger domain, 2A /FL=gb:AB032254.1 gb:NM_013449.1 NM_013449 bromodomain adjacent to zinc finger domain, 2A BAZ2A 11176 NM_013449 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // non-traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005731 // nucleolus organizer region // non-traceable author statement 0003677 // DNA binding // non-traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // non-traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201356_at BF129339 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF129339 /FEA=EST /DB_XREF=gi:10968379 /DB_XREF=est:601810961R1 /CLONE=IMAGE:4053975 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1 BF129339 splicing factor 3a, subunit 1, 120kDa SF3A1 10291 NM_001005409 /// NM_005877 0000389 // nuclear mRNA 3'-splice site recognition // traceable author statement /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0006464 // protein modification process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005684 // U2-dependent spliceosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201357_s_at NM_005877 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005877.1 /DEF=Homo sapiens splicing factor 3a, subunit 1, 120kD (SF3A1), mRNA. /FEA=mRNA /GEN=SF3A1 /PROD=splicing factor 3a, subunit 1, 120kD /DB_XREF=gi:5032086 /UG=Hs.288883 splicing factor 3a, subunit 1, 120kD /FL=gb:NM_005877.1 NM_005877 splicing factor 3a, subunit 1, 120kDa SF3A1 10291 NM_001005409 /// NM_005877 0000389 // nuclear mRNA 3'-splice site recognition // traceable author statement /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from mutant phenotype /// 0006464 // protein modification process // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005684 // U2-dependent spliceosome // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201358_s_at NM_016451 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1 NM_016451 coatomer protein complex, subunit beta 1 COPB1 1315 NM_016451 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030126 // COPI vesicle coat // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 201359_at NM_016451 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016451.1 /DEF=Homo sapiens coatomer protein complex, subunit beta (COPB), mRNA. /FEA=mRNA /GEN=COPB /PROD=coatomer protein complex, subunit beta /DB_XREF=gi:7705368 /UG=Hs.3059 coatomer protein complex, subunit beta /FL=gb:AF084457.1 gb:AL136593.1 gb:NM_016451.1 NM_016451 coatomer protein complex, subunit beta 1 COPB1 1315 NM_016451 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from sequence or structural similarity /// 0006891 // intra-Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016044 // membrane organization // not recorded /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005798 // Golgi-associated vesicle // traceable author statement /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030126 // COPI vesicle coat // inferred from sequence or structural similarity /// 0030126 // COPI vesicle coat // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 201360_at NM_000099 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000099.1 /DEF=Homo sapiens cystatin C (amyloid angiopathy and cerebral hemorrhage) (CST3), mRNA. /FEA=mRNA /GEN=CST3 /PROD=cystatin C (amyloid angiopathy and cerebralhemorrhage) /DB_XREF=gi:4503106 /UG=Hs.135084 cystatin C (amyloid angiopathy and cerebral hemorrhage) /FL=gb:NM_000099.1 NM_000099 cystatin C CST3 1471 NM_000099 0006952 // defense response // inferred from direct assay /// 0010466 // negative regulation of peptidase activity // inferred from direct assay /// 0010703 // negative regulation of histolysis // inferred by curator /// 0010711 // negative regulation of collagen catabolic process // inferred from expression pattern /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from expression pattern /// 0034103 // regulation of tissue remodeling // inferred from expression pattern /// 0043206 // fibril organization // inferred from genetic interaction /// 0060311 // negative regulation of elastin catabolic process // inferred from mutant phenotype /// 0060313 // negative regulation of blood vessel remodeling // inferred from expression pattern 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // inferred from mutant phenotype /// 0005615 // extracellular space // inferred from direct assay 0001540 // beta-amyloid binding // inferred from physical interaction /// 0002020 // protease binding // inferred from physical interaction /// 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine protease inhibitor activity // inferred from electronic annotation /// 0004869 // cysteine protease inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from sequence or structural similarity 201361_at NM_024092 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024092.1 /DEF=Homo sapiens hypothetical protein MGC5508 (MGC5508), mRNA. /FEA=mRNA /GEN=MGC5508 /PROD=hypothetical protein MGC5508 /DB_XREF=gi:13129091 /UG=Hs.13662 hypothetical protein MGC5508 /FL=gb:BC001309.1 gb:NM_024092.1 NM_024092 transmembrane protein 109 TMEM109 79073 NM_024092 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation /// 0033017 // sarcoplasmic reticulum membrane // inferred from electronic annotation 201362_at AF205218 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF205218.1 /DEF=Homo sapiens NS1-binding protein-like protein mRNA, complete cds. /FEA=mRNA /PROD=NS1-binding protein-like protein /DB_XREF=gi:12003206 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1 AF205218 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosome // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201363_s_at AB020657 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB020657.1 /DEF=Homo sapiens mRNA for KIAA0850 protein, complete cds. /FEA=mRNA /GEN=KIAA0850 /PROD=KIAA0850 protein /DB_XREF=gi:4240188 /UG=Hs.197298 NS1-binding protein /FL=gb:AF205218.1 gb:AB020657.1 gb:AF161553.1 gb:NM_016389.1 AB020657 influenza virus NS1A binding protein IVNS1ABP 10625 NM_006469 0006383 // transcription from RNA polymerase III promoter // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // traceable author statement /// 0005681 // spliceosome // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201364_s_at AF242521 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF242521.1 /DEF=Homo sapiens ornithine decarboxylase antizyme mRNA, complete cds. /FEA=mRNA /PROD=ornithine decarboxylase antizyme /DB_XREF=gi:9802039 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1 AF242521 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006595 // polyamine metabolic process // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // traceable author statement /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201365_at NM_002537 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002537.1 /DEF=Homo sapiens ornithine decarboxylase antizyme 2 (OAZ2), mRNA. /FEA=mRNA /GEN=OAZ2 /PROD=ornithine decarboxylase antizyme 2 /DB_XREF=gi:9845506 /UG=Hs.74563 ornithine decarboxylase antizyme 2 /FL=gb:AF057297.1 gb:AF242521.1 gb:NM_002537.1 NM_002537 ornithine decarboxylase antizyme 2 OAZ2 4947 NM_002537 0006595 // polyamine metabolic process // traceable author statement 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008073 // ornithine decarboxylase inhibitor activity // traceable author statement /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201366_at NM_004034 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004034.1 /DEF=Homo sapiens annexin A7 (ANXA7), transcript variant 2, mRNA. /FEA=mRNA /GEN=ANXA7 /PROD=annexin VII isoform 2 /DB_XREF=gi:4809278 /UG=Hs.78637 annexin A7 /FL=gb:NM_004034.1 NM_004034 annexin A7 ANXA7 310 NM_001156 /// NM_004034 0006874 // cellular calcium ion homeostasis // inferred from electronic annotation /// 0007599 // hemostasis // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008360 // regulation of cell shape // inferred from electronic annotation /// 0009651 // response to salt stress // inferred from electronic annotation /// 0009992 // cellular water homeostasis // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005626 // insoluble fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation 201367_s_at AI356398 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI356398 /FEA=EST /DB_XREF=gi:4108019 /DB_XREF=est:qz26f08.x1 /CLONE=IMAGE:2028039 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 AI356398 zinc finger protein 36, C3H type-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201368_at U07802 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:U07802 /DEF=Human Tis11d gene, complete cds /FEA=mRNA /DB_XREF=gi:984508 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 U07802 zinc finger protein 36, C3H type-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201369_s_at NM_006887 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006887.1 /DEF=Homo sapiens butyrate response factor 2 (EGF-response factor 2) (BRF2), mRNA. /FEA=mRNA /GEN=BRF2 /PROD=butyrate response factor 2 (EGF-response factor2) /DB_XREF=gi:5901899 /UG=Hs.78909 butyrate response factor 2 (EGF-response factor 2) /FL=gb:BC005010.1 gb:NM_006887.1 NM_006887 zinc finger protein 36, C3H type-like 2 ZFP36L2 678 NM_006887 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0043488 // regulation of mRNA stability // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201370_s_at AU145232 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU145232 /FEA=EST /DB_XREF=gi:11006753 /DB_XREF=est:AU145232 /CLONE=HEMBA1004254 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 AU145232 cullin 3 CUL3 8452 NM_003590 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201371_s_at AF062537 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF062537.1 /DEF=Homo sapiens cullin 3 mRNA, complete cds. /FEA=mRNA /PROD=cullin 3 /DB_XREF=gi:3139078 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 AF062537 cullin 3 CUL3 8452 NM_003590 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201372_s_at NM_003590 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003590.1 /DEF=Homo sapiens cullin 3 (CUL3), mRNA. /FEA=mRNA /GEN=CUL3 /PROD=cullin 3 /DB_XREF=gi:4503164 /UG=Hs.78946 cullin 3 /FL=gb:AF062537.1 gb:AB014517.1 gb:AF052147.1 gb:AF064087.1 gb:NM_003590.1 NM_003590 cullin 3 CUL3 8452 NM_003590 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008054 // cyclin catabolic process // inferred from direct assay /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201373_at NM_000445 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000445.1 /DEF=Homo sapiens plectin 1, intermediate filament binding protein, 500kD (PLEC1), mRNA. /FEA=mRNA /GEN=PLEC1 /PROD=plectin 1, intermediate filament bindingprotein, 500kD /DB_XREF=gi:4505876 /UG=Hs.79706 plectin 1, intermediate filament binding protein, 500kD /FL=gb:U53204.1 gb:NM_000445.1 NM_000445 plectin 1, intermediate filament binding protein 500kDa PLEC1 5339 NM_000445 /// NM_201378 /// NM_201379 /// NM_201380 /// NM_201381 /// NM_201382 /// NM_201383 /// NM_201384 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // non-traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // traceable author statement 201374_x_at AI379894 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI379894 /FEA=EST /DB_XREF=gi:4189747 /DB_XREF=est:tc64g11.x1 /CLONE=IMAGE:2069444 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1 AI379894 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0007498 // mesoderm development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0042221 // response to chemical stimulus // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201375_s_at NM_004156 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004156.1 /DEF=Homo sapiens protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (PPP2CB), mRNA. /FEA=mRNA /GEN=PPP2CB /PROD=protein phosphatase 2 (formerly 2A), catalyticsubunit, beta isoform /DB_XREF=gi:4758951 /UG=Hs.80350 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform /FL=gb:NM_004156.1 NM_004156 protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform PPP2CB 5516 NM_001009552 /// NM_004156 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0007498 // mesoderm development // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0042221 // response to chemical stimulus // inferred from electronic annotation /// 0042542 // response to hydrogen peroxide // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043161 // proteasomal ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0046677 // response to antibiotic // inferred from electronic annotation 0000159 // protein phosphatase type 2A complex // traceable author statement /// 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201376_s_at AI591354 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI591354 /FEA=EST /DB_XREF=gi:4600402 /DB_XREF=est:ts10e04.x1 /CLONE=IMAGE:2228190 /UG=Hs.808 heterogeneous nuclear ribonucleoprotein F /FL=gb:BC001432.1 gb:L28010.1 gb:NM_004966.1 AI591354 heterogeneous nuclear ribonucleoprotein F HNRNPF 3185 NM_001098204 /// NM_001098205 /// NM_001098206 /// NM_001098207 /// NM_001098208 /// NM_004966 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0043484 // regulation of RNA splicing // inferred from mutant phenotype 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201377_at NM_014847 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1 NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_014847 0005515 // protein binding // inferred from physical interaction 201378_s_at NM_014847 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014847.1 /DEF=Homo sapiens KIAA0144 gene product (KIAA0144), mRNA. /FEA=mRNA /GEN=KIAA0144 /PROD=KIAA0144 gene product /DB_XREF=gi:7661941 /UG=Hs.8127 KIAA0144 gene product /FL=gb:D63478.1 gb:NM_014847.1 NM_014847 ubiquitin associated protein 2-like UBAP2L 9898 NM_001127320 /// NM_014847 0005515 // protein binding // inferred from physical interaction 201379_s_at NM_003288 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003288.1 /DEF=Homo sapiens tumor protein D52-like 2 (TPD52L2), mRNA. /FEA=mRNA /GEN=TPD52L2 /PROD=tumor protein D52-like 2 /DB_XREF=gi:4507642 /UG=Hs.154718 tumor protein D52-like 2 /FL=gb:AF004430.1 gb:NM_003288.1 NM_003288 tumor protein D52-like 2 TPD52L2 7165 NM_003288 /// NM_199359 /// NM_199360 /// NM_199361 /// NM_199362 /// NM_199363 0005515 // protein binding // inferred from physical interaction 201380_at NM_006371 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006371.1 /DEF=Homo sapiens cartilage associated protein (CRTAP), mRNA. /FEA=mRNA /GEN=CRTAP /PROD=cartilage associated protein /DB_XREF=gi:5453600 /UG=Hs.155481 cartilage associated protein /FL=gb:NM_006371.1 NM_006371 cartilage associated protein CRTAP 10491 NM_006371 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation 201381_x_at AF057356 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF057356.1 /DEF=Homo sapiens calcyclin binding protein mRNA, complete cds. /FEA=mRNA /PROD=calcyclin binding protein /DB_XREF=gi:3063652 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1 AF057356 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201382_at NM_014412 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014412.1 /DEF=Homo sapiens calcyclin binding protein (CACYBP), mRNA. /FEA=mRNA /GEN=CACYBP /PROD=calcyclin binding protein /DB_XREF=gi:7656951 /UG=Hs.27258 calcyclin binding protein /FL=gb:AF314752.1 gb:AF057356.1 gb:NM_014412.1 NM_014412 calcyclin binding protein CACYBP 27101 NM_001007214 /// NM_014412 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201383_s_at AL044170 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL044170 /FEA=EST /DB_XREF=gi:5935951 /DB_XREF=est:DKFZp434P2128_s1 /CLONE=DKFZp434P2128 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1 AL044170 similar to neighbor of BRCA1 gene 1 /// neighbor of BRCA1 gene 1 LOC100133166 /// NBR1 100133166 /// 4077 NM_005899 /// NM_031858 /// NM_031862 /// XM_001719040 0005525 // GTP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201384_s_at NM_005899 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005899.1 /DEF=Homo sapiens membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) (M17S2), mRNA. /FEA=mRNA /GEN=M17S2 /PROD=membrane component, chromosome 17, surfacemarker 2 (ovarian carcinoma antigen CA125) /DB_XREF=gi:5174504 /UG=Hs.277721 membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125) /FL=gb:D30756.1 gb:NM_005899.1 NM_005899 similar to neighbor of BRCA1 gene 1 /// neighbor of BRCA1 gene 1 LOC100133166 /// NBR1 100133166 /// 4077 NM_005899 /// NM_031858 /// NM_031862 /// XM_001719040 0005525 // GTP binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201385_at NM_001358 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001358.1 /DEF=Homo sapiens DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 (DDX15), mRNA. /FEA=mRNA /GEN=DDX15 /PROD=DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /DB_XREF=gi:4557516 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1 NM_001358 DEAH (Asp-Glu-Ala-His) box polypeptide 15 DHX15 1665 NM_001358 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005689 // U12-dependent spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201386_s_at AF279891 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF279891.1 /DEF=Homo sapiens dead box protein 15 mRNA, complete cds. /FEA=mRNA /PROD=dead box protein 15 /DB_XREF=gi:9624452 /UG=Hs.5683 DEADH (Asp-Glu-Ala-AspHis) box polypeptide 15 /FL=gb:AB001636.1 gb:NM_001358.1 gb:AF279891.1 AF279891 DEAH (Asp-Glu-Ala-His) box polypeptide 15 DHX15 1665 NM_001358 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred by curator /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005689 // U12-dependent spliceosome // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003724 // RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201387_s_at NM_004181 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004181.1 /DEF=Homo sapiens ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mRNA. /FEA=mRNA /GEN=UCHL1 /PROD=ubiquitin carboxyl-terminal esterase L1(ubiquitin thiolesterase) /DB_XREF=gi:4759283 /UG=Hs.76118 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) /FL=gb:BC000332.1 gb:BC005117.1 gb:NM_004181.1 NM_004181 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) UCHL1 7345 NM_004181 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007409 // axonogenesis // inferred from electronic annotation /// 0007412 // axon target recognition // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from direct assay /// 0019896 // axon transport of mitochondrion // inferred from electronic annotation /// 0042755 // eating behavior // inferred from electronic annotation /// 0050905 // neuromuscular process // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0043025 // cell soma // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from direct assay /// 0004221 // ubiquitin thiolesterase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0008242 // omega peptidase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from electronic annotation 201388_at NM_002809 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002809.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 (PSMD3), mRNA. /FEA=mRNA /GEN=PSMD3 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 3 /DB_XREF=gi:4506228 /UG=Hs.9736 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 /FL=gb:BC000074.1 gb:BC004859.1 gb:D67025.1 gb:AF091075.1 gb:NM_002809.1 NM_002809 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 PSMD3 5709 NM_002809 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0042176 // regulation of protein catabolic process // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // inferred from electronic annotation /// 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0030234 // enzyme regulator activity // inferred from electronic annotation 201389_at NM_002205 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002205.1 /DEF=Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), mRNA. /FEA=mRNA /GEN=ITGA5 /PROD=integrin alpha 5 precursor /DB_XREF=gi:4504750 /UG=Hs.149609 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) /FL=gb:NM_002205.1 NM_002205 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) ITGA5 3678 NM_002205 0007044 // cell-substrate junction assembly // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007157 // heterophilic cell adhesion // inferred from electronic annotation /// 0007159 // leukocyte adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation /// 0033631 // cell-cell adhesion mediated by integrin // inferred from electronic annotation /// 0035313 // wound healing, spreading of epidermal cells // inferred from expression pattern /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0001726 // ruffle // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005911 // cell-cell junction // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008305 // integrin complex // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation /// 0032587 // ruffle membrane // inferred from direct assay 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201390_s_at NM_001320 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001320.1 /DEF=Homo sapiens casein kinase 2, beta polypeptide (CSNK2B), mRNA. /FEA=mRNA /GEN=CSNK2B /PROD=casein kinase 2, beta polypeptide /DB_XREF=gi:10334850 /UG=Hs.165843 casein kinase 2, beta polypeptide /FL=gb:NM_001320.1 NM_001320 casein kinase 2, beta polypeptide /// lymphocyte antigen 6 complex, locus G5B CSNK2B /// LY6G5B 1460 /// 58496 NM_001320 /// NM_021221 0006952 // defense response // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007584 // response to nutrient // inferred from electronic annotation /// 0016055 // Wnt receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005956 // protein kinase CK2 complex // inferred from electronic annotation /// 0005956 // protein kinase CK2 complex // non-traceable author statement 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008605 // protein kinase CK2 regulator activity // inferred from electronic annotation /// 0008605 // protein kinase CK2 regulator activity // non-traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019904 // protein domain specific binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from electronic annotation 201391_at NM_016292 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016292.1 /DEF=Homo sapiens heat shock protein 75 (TRAP1), mRNA. /FEA=mRNA /GEN=TRAP1 /PROD=tumor necrosis factor type 1 receptor associatedprotein /DB_XREF=gi:7706484 /UG=Hs.182366 heat shock protein 75 /FL=gb:BC002994.1 gb:AF154108.1 gb:NM_016292.1 NM_016292 TNF receptor-associated protein 1 TRAP1 10131 NM_016292 0006457 // protein folding // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005164 // tumor necrosis factor receptor binding // non-traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // inferred from electronic annotation 201392_s_at BG031974 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG031974 /FEA=EST /DB_XREF=gi:12422804 /DB_XREF=est:602300668F1 /CLONE=IMAGE:4402217 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1 BG031974 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation 201393_s_at NM_000876 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000876.1 /DEF=Homo sapiens insulin-like growth factor 2 receptor (IGF2R), mRNA. /FEA=mRNA /GEN=IGF2R /PROD=insulin-like growth factor 2 receptor /DB_XREF=gi:4504610 /UG=Hs.76473 insulin-like growth factor 2 receptor /FL=gb:J03528.1 gb:NM_000876.1 NM_000876 insulin-like growth factor 2 receptor IGF2R 3482 NM_000876 0006810 // transport // inferred from electronic annotation /// 0006898 // receptor-mediated endocytosis // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005624 // membrane fraction // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005641 // nuclear envelope lumen // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030140 // trans-Golgi network transport vesicle // inferred from direct assay 0001948 // glycoprotein binding // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005010 // insulin-like growth factor receptor activity // traceable author statement /// 0005215 // transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0005537 // mannose binding // inferred from electronic annotation 201394_s_at U23946 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U23946.1 /DEF=Human putative tumor suppressor (LUCA15) mRNA, complete cds. /FEA=mRNA /GEN=LUCA15 /DB_XREF=gi:1244403 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1 U23946 RNA binding motif protein 5 RBM5 10181 NM_005778 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201395_at NM_005778 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005778.1 /DEF=Homo sapiens RNA binding motif protein 5 (RBM5), mRNA. /FEA=mRNA /GEN=RBM5 /PROD=RNA binding motif protein 5 /DB_XREF=gi:5032030 /UG=Hs.201675 RNA binding motif protein 5 /FL=gb:U23946.1 gb:BC002957.1 gb:AF091263.1 gb:NM_005778.1 NM_005778 RNA binding motif protein 5 RBM5 10181 NM_005778 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201396_s_at NM_003021 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003021.2 /DEF=Homo sapiens small glutamine-rich tetratricopeptide repeat (TPR)-containing (SGT), mRNA. /FEA=mRNA /GEN=SGT /PROD=small glutamine-rich tetratricopeptide /DB_XREF=gi:13259553 /UG=Hs.203910 small glutamine-rich tetratricopeptide repeat (TPR)-containing /FL=gb:BC000390.1 gb:NM_003021.2 gb:BC005165.1 gb:AL050156.1 NM_003021 small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha SGTA 6449 NM_003021 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201397_at NM_006623 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006623.1 /DEF=Homo sapiens phosphoglycerate dehydrogenase (PHGDH), mRNA. /FEA=mRNA /GEN=PHGDH /PROD=phosphoglycerate dehydrogenase /DB_XREF=gi:5729973 /UG=Hs.3343 phosphoglycerate dehydrogenase /FL=gb:BC000303.1 gb:BC001349.1 gb:AF006043.1 gb:NM_006623.1 gb:AF171237.1 NM_006623 phosphoglycerate dehydrogenase PHGDH 26227 NM_006623 0006564 // L-serine biosynthetic process // inferred from electronic annotation /// 0007420 // brain development // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008652 // amino acid biosynthetic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004617 // phosphoglycerate dehydrogenase activity // inferred from electronic annotation /// 0004617 // phosphoglycerate dehydrogenase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0048037 // cofactor binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from electronic annotation 201398_s_at BC000687 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000687.1 /DEF=Homo sapiens, translocating chain-associating membrane protein, clone MGC:784, mRNA, complete cds. /FEA=mRNA /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:12653796 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1 BC000687 translocation associated membrane protein 1 TRAM1 23471 NM_014294 /// XM_001721007 /// XM_001721035 /// XM_001721065 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201399_s_at NM_014294 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014294.1 /DEF=Homo sapiens translocating chain-associating membrane protein (TRAM), mRNA. /FEA=mRNA /GEN=TRAM /PROD=translocating chain-associating membraneprotein /DB_XREF=gi:7657654 /UG=Hs.4147 translocating chain-associating membrane protein /FL=gb:BC000687.1 gb:NM_014294.1 NM_014294 translocation associated membrane protein 1 TRAM1 23471 NM_014294 /// XM_001721007 /// XM_001721035 /// XM_001721065 0006613 // cotranslational protein targeting to membrane // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201400_at NM_002795 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002795.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, beta type, 3 (PSMB3), mRNA. /FEA=mRNA /GEN=PSMB3 /PROD=proteasome (prosome, macropain) subunit, betatype, 3 /DB_XREF=gi:4506196 /UG=Hs.82793 proteasome (prosome, macropain) subunit, beta type, 3 /FL=gb:NM_002795.1 gb:D26598.1 NM_002795 proteasome (prosome, macropain) subunit, beta type, 3 PSMB3 5691 NM_002795 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201401_s_at M80776 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M80776.1 /DEF=Human beta-adrenergic receptor kinase 1 mRNA, complete cds. /FEA=mRNA /GEN=receptor kinase /PROD=receptor kinase /DB_XREF=gi:179334 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2 M80776 adrenergic, beta, receptor kinase 1 ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 201402_at NM_001619 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001619.2 /DEF=Homo sapiens adrenergic, beta, receptor kinase 1 (ADRBK1), mRNA. /FEA=mRNA /GEN=ADRBK1 /PROD=beta adrenergic receptor kinase 1 /DB_XREF=gi:6138971 /UG=Hs.83636 adrenergic, beta, receptor kinase 1 /FL=gb:M80776.1 gb:NM_001619.2 NM_001619 adrenergic, beta, receptor kinase 1 ADRBK1 156 NM_001619 0002026 // regulation of the force of heart contraction // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0002029 // desensitization of G-protein coupled receptor protein signaling pathway // inferred from sequence or structural similarity /// 0003108 // negative regulation of the force of heart contraction by chemical signal // inferred from mutant phenotype /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0007213 // acetylcholine receptor signaling, muscarinic pathway // inferred from sequence or structural similarity /// 0007217 // tachykinin signaling pathway // inferred from direct assay /// 0007507 // heart development // inferred from electronic annotation /// 0018105 // peptidyl-serine phosphorylation // inferred from sequence or structural similarity /// 0033605 // positive regulation of catecholamine secretion // inferred from sequence or structural similarity /// 0045988 // negative regulation of striated muscle contraction // inferred from mutant phenotype /// 0060048 // cardiac muscle contraction // inferred from mutant phenotype 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from sequence or structural similarity /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from electronic annotation /// 0004703 // G-protein coupled receptor kinase activity // inferred from sequence or structural similarity /// 0004871 // signal transducer activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047696 // beta-adrenergic receptor kinase activity // inferred from electronic annotation 201403_s_at NM_004528 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004528.1 /DEF=Homo sapiens microsomal glutathione S-transferase 3 (MGST3), mRNA. /FEA=mRNA /GEN=MGST3 /PROD=microsomal glutathione S-transferase 3 /DB_XREF=gi:4758713 /UG=Hs.111811 microsomal glutathione S-transferase 3 /FL=gb:BC000505.1 gb:BC003034.1 gb:AF026977.1 gb:NM_004528.1 NM_004528 microsomal glutathione S-transferase 3 MGST3 4259 NM_004528 0006629 // lipid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // traceable author statement /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004364 // glutathione transferase activity // traceable author statement /// 0004364 // glutathione transferase activity // inferred from electronic annotation /// 0004601 // peroxidase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 201404_x_at BC000268 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000268.1 /DEF=Homo sapiens, proteasome (prosome, macropain) subunit, beta type, 2, clone MGC:1664, mRNA, complete cds. /FEA=mRNA /PROD=proteasome (prosome, macropain) subunit, betatype, 2 /DB_XREF=gi:12653014 /UG=Hs.1390 proteasome (prosome, macropain) subunit, beta type, 2 /FL=gb:BC000268.1 gb:NM_002794.1 gb:D26599.1 BC000268 proteasome (prosome, macropain) subunit, beta type, 2 PSMB2 5690 NM_002794 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201405_s_at NM_006833 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006833.1 /DEF=Homo sapiens COP9 subunit 6 (MOV34 homolog, 34 kD) (MOV34-34KD), mRNA. /FEA=mRNA /GEN=MOV34-34KD /PROD=COP9 subunit 6 (MOV34 homolog, 34 kD) /DB_XREF=gi:5803095 /UG=Hs.15591 COP9 subunit 6 (MOV34 homolog, 34 kD) /FL=gb:BC002520.1 gb:U70735.1 gb:NM_006833.1 NM_006833 COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) COPS6 10980 NM_006833 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008180 // signalosome // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201406_at NM_021029 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021029.1 /DEF=Homo sapiens ribosomal protein L44 (RPL44), mRNA. /FEA=mRNA /GEN=RPL44 /PROD=ribosomal protein L44 /DB_XREF=gi:10445222 /UG=Hs.178391 ribosomal protein L44 /FL=gb:NM_021029.1 gb:BC001781.1 NM_021029 ribosomal protein L36a RPL36A 6173 NM_021029 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // not recorded 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030530 // heterogeneous nuclear ribonucleoprotein complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201407_s_at AI186712 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI186712 /FEA=EST /DB_XREF=gi:3737350 /DB_XREF=est:qe82f01.x1 /CLONE=IMAGE:1745497 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 AI186712 protein phosphatase 1, catalytic subunit, beta isoform PPP1CB 5500 NM_002709 /// NM_206876 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201408_at W67887 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:W67887 /FEA=EST /DB_XREF=gi:1376776 /DB_XREF=est:zd38c11.s1 /CLONE=IMAGE:342932 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 W67887 protein phosphatase 1, catalytic subunit, beta isoform PPP1CB 5500 NM_002709 /// NM_206876 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201409_s_at NM_002709 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002709.1 /DEF=Homo sapiens protein phosphatase 1, catalytic subunit, beta isoform (PPP1CB), mRNA. /FEA=mRNA /GEN=PPP1CB /PROD=protein phosphatase 1, catalytic subunit, betaisoform /DB_XREF=gi:4506004 /UG=Hs.21537 protein phosphatase 1, catalytic subunit, beta isoform /FL=gb:NM_002709.1 gb:AF092905.1 NM_002709 protein phosphatase 1, catalytic subunit, beta isoform PPP1CB 5500 NM_002709 /// NM_206876 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004722 // protein serine/threonine phosphatase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201410_at AI983043 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI983043 /FEA=EST /DB_XREF=gi:5810262 /DB_XREF=est:wz30b11.x1 /CLONE=IMAGE:2559549 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1 AI983043 pleckstrin homology domain containing, family B (evectins) member 2 PLEKHB2 55041 NM_001100623 /// NM_017958 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201411_s_at NM_017958 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_017958.1 /DEF=Homo sapiens hypothetical protein FLJ20783 (FLJ20783), mRNA. /FEA=mRNA /GEN=FLJ20783 /PROD=hypothetical protein FLJ20783 /DB_XREF=gi:8923679 /UG=Hs.246885 hypothetical protein FLJ20783 /FL=gb:NM_017958.1 NM_017958 pleckstrin homology domain containing, family B (evectins) member 2 PLEKHB2 55041 NM_001100623 /// NM_017958 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201412_at NM_014045 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014045.1 /DEF=Homo sapiens DKFZP564C1940 protein (DKFZP564C1940), mRNA. /FEA=mRNA /GEN=DKFZP564C1940 /PROD=DKFZP564C1940 protein /DB_XREF=gi:13027587 /UG=Hs.3804 DKFZP564C1940 protein /FL=gb:BC000424.1 gb:NM_014045.1 gb:AF131760.1 NM_014045 low density lipoprotein receptor-related protein 10 LRP10 26020 NM_014045 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0006897 // endocytosis // inferred from electronic annotation 0005905 // coated pit // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005041 // low-density lipoprotein receptor activity // inferred from electronic annotation 201413_at NM_000414 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000414.1 /DEF=Homo sapiens hydroxysteroid (17-beta) dehydrogenase 4 (HSD17B4), mRNA. /FEA=mRNA /GEN=HSD17B4 /PROD=hydroxysteroid (17-beta) dehydrogenase 4 /DB_XREF=gi:4504504 /UG=Hs.75441 hydroxysteroid (17-beta) dehydrogenase 4 /FL=gb:BC003098.1 gb:NM_000414.1 NM_000414 hydroxysteroid (17-beta) dehydrogenase 4 HSD17B4 3295 NM_000414 0000038 // very-long-chain fatty acid metabolic process // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006635 // fatty acid beta-oxidation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation /// 0060009 // Sertoli cell development // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005777 // peroxisome // traceable author statement /// 0005782 // peroxisomal matrix // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // not recorded /// 0003857 // 3-hydroxyacyl-CoA dehydrogenase activity // inferred from electronic annotation /// 0004303 // estradiol 17-beta-dehydrogenase activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005498 // sterol carrier activity // inferred from electronic annotation /// 0005498 // sterol carrier activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015248 // sterol transporter activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016829 // lyase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0033989 // 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity // inferred from electronic annotation 201414_s_at NM_005969 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005969.1 /DEF=Homo sapiens nucleosome assembly protein 1-like 4 (NAP1L4), mRNA. /FEA=mRNA /GEN=NAP1L4 /PROD=nucleosome assembly protein 1-like 4 /DB_XREF=gi:5174612 /UG=Hs.78103 nucleosome assembly protein 1-like 4 /FL=gb:U77456.1 gb:NM_005969.1 NM_005969 nucleosome assembly protein 1-like 4 NAP1L4 4676 NM_005969 0006334 // nucleosome assembly // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005678 // chromatin assembly complex // traceable author statement /// 0005737 // cytoplasm // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0051082 // unfolded protein binding // traceable author statement 201415_at NM_000178 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000178.1 /DEF=Homo sapiens glutathione synthetase (GSS), mRNA. /FEA=mRNA /GEN=GSS /PROD=glutathione synthetase /DB_XREF=gi:4504168 /UG=Hs.82327 glutathione synthetase /FL=gb:U34683.1 gb:NM_000178.1 NM_000178 glutathione synthetase GSS 2937 NM_000178 0006520 // amino acid metabolic process // traceable author statement /// 0006750 // glutathione biosynthetic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007399 // nervous system development // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004363 // glutathione synthase activity // traceable author statement /// 0004363 // glutathione synthase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201416_at BG528420 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG528420 /FEA=EST /DB_XREF=gi:13519957 /DB_XREF=est:602579853F1 /CLONE=IMAGE:4719060 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 BG528420 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt receptor signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptosis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0060070 // Wnt receptor signaling pathway through beta-catenin // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201417_at AL136179 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL136179 /DEF=Human DNA sequence from clone RP3-322L4 on chromosome 6. Contains the SOX4 gene for SRY (sex determining region Y)-box 4, a pseudogene similar to predicted fly, worm and yeast genes, ESTs, STSs, GSSs and four CpG islands /FEA=mRNA /DB_XREF=gi:8649149 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 AL136179 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt receptor signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptosis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0060070 // Wnt receptor signaling pathway through beta-catenin // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201418_s_at NM_003107 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003107.1 /DEF=Homo sapiens SRY (sex determining region Y)-box 4 (SOX4), mRNA. /FEA=mRNA /GEN=SOX4 /PROD=SRY (sex determining region Y)-box 4 /DB_XREF=gi:4507162 /UG=Hs.83484 SRY (sex determining region Y)-box 4 /FL=gb:NM_003107.1 NM_003107 SRY (sex determining region Y)-box 4 SOX4 6659 NM_003107 0002328 // pro-B cell differentiation // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007507 // heart development // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // inferred from mutant phenotype /// 0030177 // positive regulation of Wnt receptor signaling pathway // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptosis // inferred from mutant phenotype /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-dependent // inferred from direct assay /// 0050821 // protein stabilization // inferred from mutant phenotype /// 0050821 // protein stabilization // inferred from sequence or structural similarity /// 0060070 // Wnt receptor signaling pathway through beta-catenin // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201419_at NM_004656 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004656.1 /DEF=Homo sapiens BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (BAP1), mRNA. /FEA=mRNA /GEN=BAP1 /PROD=BRCA1 associated protein-1 (ubiquitincarboxy-terminal hydrolase) /DB_XREF=gi:4757835 /UG=Hs.106674 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) /FL=gb:BC001596.1 gb:AF045581.1 gb:NM_004656.1 NM_004656 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) BAP1 8314 NM_004656 0006464 // protein modification process // non-traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // non-traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201420_s_at BF975273 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF975273 /FEA=EST /DB_XREF=gi:12342488 /DB_XREF=est:602244783F1 /CLONE=IMAGE:4335765 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1 BF975273 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP biogenesis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 201421_s_at NM_024102 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024102.1 /DEF=Homo sapiens hypothetical protein MGC2722 (MGC2722), mRNA. /FEA=mRNA /GEN=MGC2722 /PROD=hypothetical protein MGC2722 /DB_XREF=gi:13129109 /UG=Hs.11039 hypothetical protein MGC2722 /FL=gb:BC001679.1 gb:NM_024102.1 NM_024102 WD repeat domain 77 WDR77 79084 NM_024102 0000387 // spliceosomal snRNP biogenesis // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 201422_at NM_006332 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006332.1 /DEF=Homo sapiens interferon, gamma-inducible protein 30 (IFI30), mRNA. /FEA=mRNA /GEN=IFI30 /PROD=interferon, gamma-inducible protein 30 /DB_XREF=gi:5453695 /UG=Hs.14623 interferon, gamma-inducible protein 30 /FL=gb:J03909.1 gb:NM_006332.1 gb:AF097362.1 NM_006332 interferon, gamma-inducible protein 30 IFI30 10437 NM_006332 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005576 // extracellular region // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement 0016491 // oxidoreductase activity // inferred from electronic annotation 201423_s_at AL037208 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL037208 /FEA=EST /DB_XREF=gi:5406648 /DB_XREF=est:DKFZp564B1169_s1 /CLONE=DKFZp564B1169 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1 AL037208 cullin 4A CUL4A 8451 NM_001008895 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201424_s_at NM_003589 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003589.1 /DEF=Homo sapiens cullin 4A (CUL4A), mRNA. /FEA=mRNA /GEN=CUL4A /PROD=cullin 4A /DB_XREF=gi:11140810 /UG=Hs.183874 cullin 4A /FL=gb:NM_003589.1 gb:AF077188.1 NM_003589 cullin 4A CUL4A 8451 NM_001008895 /// NM_003589 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement 0031461 // cullin-RING ubiquitin ligase complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from electronic annotation 201425_at NM_000690 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000690.1 /DEF=Homo sapiens aldehyde dehydrogenase 2, mitochondrial (ALDH2), mRNA. /FEA=mRNA /GEN=ALDH2 /PROD=aldehyde dehydrogenase 2, mitochondrial /DB_XREF=gi:4502032 /UG=Hs.195432 aldehyde dehydrogenase 2 family (mitochondrial) /FL=gb:BC002967.1 gb:NM_000690.1 NM_000690 aldehyde dehydrogenase 2 family (mitochondrial) ALDH2 217 NM_000690 0005975 // carbohydrate metabolic process // traceable author statement /// 0006066 // cellular alcohol metabolic process // traceable author statement /// 0007218 // neuropeptide signaling pathway // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0004029 // aldehyde dehydrogenase (NAD) activity // traceable author statement /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0004030 // aldehyde dehydrogenase [NAD(P)+] activity // traceable author statement /// 0005184 // neuropeptide hormone activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201426_s_at AI922599 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI922599 /FEA=EST /DB_XREF=gi:5658563 /DB_XREF=est:wm90b11.x1 /CLONE=IMAGE:2443197 /UG=Hs.297753 vimentin /FL=gb:BC000163.2 gb:NM_003380.1 AI922599 vimentin VIM 7431 NM_003380 0006928 // cell motion // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045103 // intermediate filament-based process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay /// 0005882 // intermediate filament // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred from direct assay /// 0005515 // protein binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201427_s_at NM_005410 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005410.1 /DEF=Homo sapiens selenoprotein P, plasma, 1 (SEPP1), mRNA. /FEA=mRNA /GEN=SEPP1 /PROD=selenoprotein P precursor /DB_XREF=gi:4885590 /UG=Hs.3314 selenoprotein P, plasma, 1 /FL=gb:NM_005410.1 NM_005410 selenoprotein P, plasma, 1 SEPP1 6414 NM_001085486 /// NM_001093726 /// NM_005410 0001887 // selenium metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // traceable author statement /// 0007420 // brain development // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0008430 // selenium binding // inferred from electronic annotation /// 0008430 // selenium binding // traceable author statement 201428_at NM_001305 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001305.1 /DEF=Homo sapiens claudin 4 (CLDN4), mRNA. /FEA=mRNA /GEN=CLDN4 /PROD=claudin 4 /DB_XREF=gi:4502876 /UG=Hs.5372 claudin 4 /FL=gb:BC000671.1 gb:AB000712.1 gb:NM_001305.1 NM_001305 claudin 4 CLDN4 1364 NM_001305 0009405 // pathogenesis // traceable author statement /// 0016338 // calcium-independent cell-cell adhesion // inferred from sequence or structural similarity 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0005923 // tight junction // inferred from sequence or structural similarity /// 0005923 // tight junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0004888 // transmembrane receptor activity // traceable author statement /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from sequence or structural similarity 201429_s_at NM_000998 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000998.1 /DEF=Homo sapiens ribosomal protein L37a (RPL37A), mRNA. /FEA=mRNA /GEN=RPL37A /PROD=ribosomal protein L37a /DB_XREF=gi:4506642 /UG=Hs.5566 ribosomal protein L37a /FL=gb:BC000555.1 gb:L06499.1 gb:NM_000998.1 NM_000998 ribosomal protein L37a RPL37A 6168 NM_000998 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201430_s_at W72516 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:W72516 /FEA=EST /DB_XREF=gi:1382173 /DB_XREF=est:zd64g05.s1 /CLONE=IMAGE:345464 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1 W72516 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001387 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004157 // dihydropyrimidinase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation 201431_s_at NM_001387 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001387.1 /DEF=Homo sapiens dihydropyrimidinase-like 3 (DPYSL3), mRNA. /FEA=mRNA /GEN=DPYSL3 /PROD=dihydropyrimidinase-like 3 /DB_XREF=gi:4503378 /UG=Hs.74566 dihydropyrimidinase-like 3 /FL=gb:D78014.1 gb:NM_001387.1 NM_001387 dihydropyrimidinase-like 3 DPYSL3 1809 NM_001387 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0007399 // nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0004157 // dihydropyrimidinase activity // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016810 // hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds // inferred from electronic annotation 201432_at NM_001752 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001752.1 /DEF=Homo sapiens catalase (CAT), mRNA. /FEA=mRNA /GEN=CAT /PROD=catalase /DB_XREF=gi:4557013 /UG=Hs.76359 catalase /FL=gb:NM_001752.1 NM_001752 catalase CAT 847 NM_001752 0000302 // response to reactive oxygen species // inferred from mutant phenotype /// 0006641 // triacylglycerol metabolic process // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0009060 // aerobic respiration // inferred from electronic annotation /// 0009650 // UV protection // inferred from mutant phenotype /// 0014068 // positive regulation of phosphoinositide 3-kinase cascade // inferred from electronic annotation /// 0020027 // hemoglobin metabolic process // inferred from electronic annotation /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0042744 // hydrogen peroxide catabolic process // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from electronic annotation /// 0051262 // protein tetramerization // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from electronic annotation 0004046 // aminoacylase activity // inferred from electronic annotation /// 0004096 // catalase activity // inferred from direct assay /// 0004096 // catalase activity // inferred from electronic annotation /// 0004601 // peroxidase activity // inferred from electronic annotation /// 0005506 // iron ion binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from electronic annotation /// 0016684 // oxidoreductase activity, acting on peroxide as acceptor // inferred from sequence or structural similarity /// 0020037 // heme binding // inferred from direct assay /// 0020037 // heme binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050661 // NADP binding // inferred from direct assay 201433_s_at NM_014754 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014754.1 /DEF=Homo sapiens phosphatidylserine synthase 1 (PTDSS1), mRNA. /FEA=mRNA /GEN=PTDSS1 /PROD=phosphatidylserine synthase 1 /DB_XREF=gi:7662646 /UG=Hs.77329 phosphatidylserine synthase 1 /FL=gb:BC004192.1 gb:BC004390.1 gb:D14694.1 gb:NM_014754.1 NM_014754 phosphatidylserine synthase 1 PTDSS1 9791 NM_014754 0006659 // phosphatidylserine biosynthetic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0016740 // transferase activity // inferred from electronic annotation 201434_at NM_003314 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003314.1 /DEF=Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA. /FEA=mRNA /GEN=TTC1 /PROD=tetratricopeptide repeat domain 1 /DB_XREF=gi:4507710 /UG=Hs.7733 tetratricopeptide repeat domain 1 /FL=gb:BC000942.1 gb:U46570.1 gb:NM_003314.1 NM_003314 tetratricopeptide repeat domain 1 TTC1 7265 NM_003314 /// XM_001717166 /// XM_001722976 /// XM_001725128 0006457 // protein folding // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0051082 // unfolded protein binding // traceable author statement 201435_s_at AW268640 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW268640 /FEA=EST /DB_XREF=gi:6655670 /DB_XREF=est:xv52a03.x1 /CLONE=IMAGE:2816716 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AW268640 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201436_at AI742789 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI742789 /FEA=EST /DB_XREF=gi:5111077 /DB_XREF=est:wg46c05.x1 /CLONE=IMAGE:2368136 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 AI742789 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201437_s_at NM_001968 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001968.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), mRNA. /FEA=mRNA /GEN=EIF4E /PROD=eukaryotic translation initiation factor 4E /DB_XREF=gi:4503534 /UG=Hs.79306 eukaryotic translation initiation factor 4E /FL=gb:M15353.1 gb:NM_001968.1 NM_001968 eukaryotic translation initiation factor 4E EIF4E 1977 NM_001130678 /// NM_001130679 /// NM_001968 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006417 // regulation of translation // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000339 // RNA cap binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0003743 // translation initiation factor activity // inferred from sequence or structural similarity /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201438_at NM_004369 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004369.1 /DEF=Homo sapiens collagen, type VI, alpha 3 (COL6A3), mRNA. /FEA=mRNA /GEN=COL6A3 /PROD=collagen, type VI, alpha 3 /DB_XREF=gi:4758027 /UG=Hs.80988 collagen, type VI, alpha 3 /FL=gb:NM_004369.1 NM_004369 collagen, type VI, alpha 3 COL6A3 1293 NM_004369 /// NM_057164 /// NM_057165 /// NM_057166 /// NM_057167 0007155 // cell adhesion // inferred from electronic annotation /// 0007517 // muscle development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005589 // collagen type VI // traceable author statement 0004866 // endopeptidase inhibitor activity // inferred from electronic annotation /// 0004867 // serine-type endopeptidase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201439_at NM_004193 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004193.1 /DEF=Homo sapiens golgi-specific brefeldin A resistance factor 1 (GBF1), mRNA. /FEA=mRNA /GEN=GBF1 /PROD=golgi-specific brefeldin A resistance factor 1 /DB_XREF=gi:4758415 /UG=Hs.155499 golgi-specific brefeldin A resistance factor 1 /FL=gb:AF068755.1 gb:NM_004193.1 NM_004193 golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1 GBF1 8729 NM_004193 0006890 // retrograde vesicle-mediated transport, Golgi to ER // not recorded /// 0006890 // retrograde vesicle-mediated transport, Golgi to ER // inferred from sequence or structural similarity /// 0016044 // membrane organization // not recorded /// 0032012 // regulation of ARF protein signal transduction // inferred from electronic annotation /// 0048205 // COPI coating of Golgi vesicle // not recorded 0000139 // Golgi membrane // not recorded /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005086 // ARF guanyl-nucleotide exchange factor activity // not recorded /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from sequence or structural similarity /// 0005086 // ARF guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201440_at NM_004818 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004818.1 /DEF=Homo sapiens prp28, U5 snRNP 100 kd protein (U5-100K), mRNA. /FEA=mRNA /GEN=U5-100K /PROD=prp28, U5 snRNP 100 kd protein /DB_XREF=gi:4759277 /UG=Hs.168103 prp28, U5 snRNP 100 kd protein /FL=gb:BC002366.1 gb:AF026402.1 gb:NM_004818.1 NM_004818 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 DDX23 9416 NM_004818 0000354 // cis assembly of pre-catalytic spliceosome // inferred by curator /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005682 // snRNP U5 // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from direct assay /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 201441_at NM_001863 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001863.2 /DEF=Homo sapiens cytochrome c oxidase subunit VIb (COX6B), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6B /PROD=cytochrome c oxidase subunit VIb /DB_XREF=gi:6680989 /UG=Hs.174031 cytochrome c oxidase subunit VIb /FL=gb:BC001015.1 gb:BC002478.1 gb:NM_001863.2 NM_001863 cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous) COX6B1 1340 NM_001863 0055114 // oxidation reduction // non-traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005758 // mitochondrial intermembrane space // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // non-traceable author statement /// 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201442_s_at AF248966 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 AF248966 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from direct assay /// 0043408 // regulation of MAPKKK cascade // inferred from direct assay 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201443_s_at AF248966 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF248966.1 /DEF=Homo sapiens HT028 mRNA, complete cds. /FEA=mRNA /PROD=HT028 /DB_XREF=gi:12005668 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 AF248966 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from direct assay /// 0043408 // regulation of MAPKKK cascade // inferred from direct assay 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201444_s_at NM_005765 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005765.1 /DEF=Homo sapiens ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 (APT6M8-9), mRNA. /FEA=mRNA /GEN=APT6M8-9 /PROD=ATPase, H+ transporting, lysosomal (vacuolarproton pump) membrane sector associated protein M8-9 /DB_XREF=gi:5031590 /UG=Hs.183434 ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9 /FL=gb:AF248966.1 gb:NM_005765.1 NM_005765 ATPase, H+ transporting, lysosomal accessory protein 2 ATP6AP2 10159 NM_005765 0002003 // angiotensin maturation // inferred from direct assay /// 0032914 // positive regulation of transforming growth factor-beta1 production // inferred from direct assay /// 0043408 // regulation of MAPKKK cascade // inferred from direct assay 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201445_at NM_001839 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001839.1 /DEF=Homo sapiens calponin 3, acidic (CNN3), mRNA. /FEA=mRNA /GEN=CNN3 /PROD=calponin 3 /DB_XREF=gi:4502922 /UG=Hs.194662 calponin 3, acidic /FL=gb:NM_001839.1 NM_001839 calponin 3, acidic CNN3 1266 NM_001839 0006939 // smooth muscle contraction // non-traceable author statement /// 0031032 // actomyosin structure organization // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // non-traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005523 // tropomyosin binding // non-traceable author statement /// 0030172 // troponin C binding // non-traceable author statement 201446_s_at BF692742 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF692742 /FEA=EST /DB_XREF=gi:11978150 /DB_XREF=est:602079823F1 /CLONE=IMAGE:4244524 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 BF692742 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement 201447_at H96549 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:H96549 /FEA=EST /DB_XREF=gi:1110035 /DB_XREF=est:yw01c09.s1 /CLONE=IMAGE:250960 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 H96549 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement 201448_at AL046419 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL046419 /FEA=EST /DB_XREF=gi:5434493 /DB_XREF=est:DKFZp434N247_s1 /CLONE=DKFZp434N247 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL046419 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement 201449_at AL567227 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL567227 /FEA=EST /DB_XREF=gi:12920378 /DB_XREF=est:AL567227 /CLONE=CS0DF027YA11 (3 prime) /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 AL567227 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement 201450_s_at NM_022037 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_022037.1 /DEF=Homo sapiens TIA1 cytotoxic granule-associated RNA-binding protein (TIA1), transcript variant 1, mRNA. /FEA=mRNA /GEN=TIA1 /PROD=TIA1 protein, isoform 1 /DB_XREF=gi:11863160 /UG=Hs.239489 TIA1 cytotoxic granule-associated RNA-binding protein /FL=gb:NM_022037.1 gb:M77142.1 NM_022037 TIA1 cytotoxic granule-associated RNA binding protein TIA1 7072 NM_022037 /// NM_022173 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008143 // poly(A) binding // traceable author statement 201451_x_at D78132 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:D78132.1 /DEF=Homo sapiens mRNA for ras-related GTP-binding protein, complete cds. /FEA=mRNA /GEN=Rheb /PROD=ras-related GTP-binding protein /DB_XREF=gi:1772344 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 D78132 Ras homolog enriched in brain RHEB 6009 NM_005614 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201452_at AW138374 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW138374 /FEA=EST /DB_XREF=gi:6142692 /DB_XREF=est:UI-H-BI1-adb-e-09-0-UI.s1 /CLONE=IMAGE:2716145 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 AW138374 Ras homolog enriched in brain RHEB 6009 NM_005614 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201453_x_at NM_005614 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005614.1 /DEF=Homo sapiens Ras homolog enriched in brain 2 (RHEB2), mRNA. /FEA=mRNA /GEN=RHEB2 /PROD=Ras homolog enriched in brain 2 /DB_XREF=gi:5032040 /UG=Hs.279903 Ras homolog enriched in brain 2 /FL=gb:D78132.1 gb:NM_005614.1 gb:AF148645.1 NM_005614 Ras homolog enriched in brain RHEB 6009 NM_005614 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201454_s_at AW055008 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW055008 /FEA=EST /DB_XREF=gi:5920711 /DB_XREF=est:wy98c09.x1 /CLONE=IMAGE:2556592 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1 AW055008 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004177 // aminopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201455_s_at AJ132583 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AJ132583.1 /DEF=Homo sapiens mRNA for puromycin sensitive aminopeptidase, partial. /FEA=mRNA /PROD=puromycin sensitive aminopeptidase /DB_XREF=gi:4210725 /UG=Hs.293007 aminopeptidase puromycin sensitive /FL=gb:NM_006310.1 AJ132583 aminopeptidase puromycin sensitive NPEPPS 9520 NM_006310 0006508 // proteolysis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0004177 // aminopeptidase activity // traceable author statement /// 0004177 // aminopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201456_s_at AU160695 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU160695 /FEA=EST /DB_XREF=gi:11022216 /DB_XREF=est:AU160695 /CLONE=Y79AA1002240 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 AU160695 budding uninhibited by benzimidazoles 3 homolog (yeast) BUB3 9184 NM_001007793 /// NM_004725 0007067 // mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded 0005515 // protein binding // inferred from physical interaction 201457_x_at AF081496 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF081496.1 /DEF=Homo sapiens kinetochore protein BUB3 (BUB3) mRNA, complete cds. /FEA=mRNA /GEN=BUB3 /PROD=kinetochore protein BUB3 /DB_XREF=gi:3639059 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 AF081496 budding uninhibited by benzimidazoles 3 homolog (yeast) BUB3 9184 NM_001007793 /// NM_004725 0007067 // mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded 0005515 // protein binding // inferred from physical interaction 201458_s_at NM_004725 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004725.1 /DEF=Homo sapiens BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog (BUB3), mRNA. /FEA=mRNA /GEN=BUB3 /PROD=BUB3 (budding uninhibited by benzimidazoles 3,yeast) homolog /DB_XREF=gi:4757879 /UG=Hs.40323 BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog /FL=gb:BC005138.1 gb:AF047472.1 gb:AF053304.1 gb:AF081496.1 gb:NM_004725.1 NM_004725 budding uninhibited by benzimidazoles 3 homolog (yeast) BUB3 9184 NM_001007793 /// NM_004725 0007067 // mitosis // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000776 // kinetochore // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // not recorded 0005515 // protein binding // inferred from physical interaction 201459_at NM_006666 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006666.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 2 (RUVBL2), mRNA. /FEA=mRNA /GEN=RUVBL2 /PROD=RuvB (E coli homolog)-like 2 /DB_XREF=gi:5730022 /UG=Hs.6455 RuvB (E coli homolog)-like 2 /FL=gb:BC000428.1 gb:BC004531.1 gb:AB024301.1 gb:AF151804.1 gb:AF155138.1 gb:NM_006666.1 gb:AL136743.1 gb:AF124607.1 NM_006666 RuvB-like 2 (E. coli) RUVBL2 10856 NM_006666 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006457 // protein folding // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003684 // damaged DNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from direct assay /// 0051082 // unfolded protein binding // traceable author statement 201460_at AI141802 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI141802 /FEA=EST /DB_XREF=gi:3649259 /DB_XREF=est:qa56e05.s1 /CLONE=IMAGE:1690784 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1 AI141802 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 0000165 // MAPKKK cascade // traceable author statement /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // not recorded /// 0007265 // Ras protein signal transduction // not recorded /// 0048255 // mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201461_s_at NM_004759 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004759.1 /DEF=Homo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), mRNA. /FEA=mRNA /GEN=MAPKAPK2 /PROD=mitogen-activated protein kinase-activatedprotein kinase 2 /DB_XREF=gi:10863900 /UG=Hs.75074 mitogen-activated protein kinase-activated protein kinase 2 /FL=gb:NM_004759.1 gb:U12779.1 NM_004759 mitogen-activated protein kinase-activated protein kinase 2 MAPKAPK2 9261 NM_004759 /// NM_032960 0000165 // MAPKKK cascade // traceable author statement /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // not recorded /// 0007265 // Ras protein signal transduction // not recorded /// 0048255 // mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004672 // protein kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004871 // signal transducer activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201462_at NM_014766 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014766.1 /DEF=Homo sapiens KIAA0193 gene product (KIAA0193), mRNA. /FEA=mRNA /GEN=KIAA0193 /PROD=KIAA0193 gene product /DB_XREF=gi:7661983 /UG=Hs.75137 KIAA0193 gene product /FL=gb:D83777.1 gb:NM_014766.1 NM_014766 secernin 1 SCRN1 9805 NM_014766 0006887 // exocytosis // inferred from sequence or structural similarity /// 0006887 // exocytosis // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay 201463_s_at NM_006755 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006755.1 /DEF=Homo sapiens transaldolase 1 (TALDO1), mRNA. /FEA=mRNA /GEN=TALDO1 /PROD=transaldolase 1 /DB_XREF=gi:5803186 /UG=Hs.77290 transaldolase 1 /FL=gb:L19437.2 gb:NM_006755.1 NM_006755 similar to transaldolase /// transaldolase 1 LOC100133665 /// TALDO1 100133665 /// 6888 NM_006755 /// XM_001718819 0005975 // carbohydrate metabolic process // traceable author statement /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006098 // pentose-phosphate shunt // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004801 // transaldolase activity // not recorded /// 0004801 // transaldolase activity // traceable author statement /// 0004801 // transaldolase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation 201464_x_at BG491844 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG491844 /FEA=EST /DB_XREF=gi:13453356 /DB_XREF=est:602535931T1 /CLONE=IMAGE:4684998 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 BG491844 jun oncogene JUN 3725 NM_002228 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0031953 // negative regulation of protein amino acid autophosphorylation // inferred from electronic annotation /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201465_s_at BC002646 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002646.1 /DEF=Homo sapiens, v-jun avian sarcoma virus 17 oncogene homolog, clone MGC:3338, mRNA, complete cds. /FEA=mRNA /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:12803622 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 BC002646 jun oncogene JUN 3725 NM_002228 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0031953 // negative regulation of protein amino acid autophosphorylation // inferred from electronic annotation /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201466_s_at NM_002228 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002228.2 /DEF=Homo sapiens v-jun avian sarcoma virus 17 oncogene homolog (JUN), mRNA. /FEA=mRNA /GEN=JUN /PROD=v-jun avian sarcoma virus 17 oncogene homolog /DB_XREF=gi:7710122 /UG=Hs.78465 v-jun avian sarcoma virus 17 oncogene homolog /FL=gb:BC002646.1 gb:NM_002228.2 NM_002228 jun oncogene JUN 3725 NM_002228 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0031953 // negative regulation of protein amino acid autophosphorylation // inferred from electronic annotation /// 0035026 // leading edge cell differentiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0000228 // nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201467_s_at AI039874 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI039874 /FEA=EST /DB_XREF=gi:3279068 /DB_XREF=est:ox97c05.x1 /CLONE=IMAGE:1664264 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1 AI039874 NAD(P)H dehydrogenase, quinone 1 NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0009636 // response to toxin // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003955 // NAD(P)H dehydrogenase (quinone) activity // traceable author statement /// 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201468_s_at NM_000903 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000903.1 /DEF=Homo sapiens diaphorase (NADHNADPH) (cytochrome b-5 reductase) (DIA4), mRNA. /FEA=mRNA /GEN=DIA4 /PROD=NAD(P)H menadione oxidoreductase 1,dioxin-inducible /DB_XREF=gi:4505414 /UG=Hs.80706 diaphorase (NADHNADPH) (cytochrome b-5 reductase) /FL=gb:J03934.1 gb:NM_000903.1 NM_000903 NAD(P)H dehydrogenase, quinone 1 NQO1 1728 NM_000903 /// NM_001025433 /// NM_001025434 0006805 // xenobiotic metabolic process // traceable author statement /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006979 // response to oxidative stress // inferred from electronic annotation /// 0007271 // synaptic transmission, cholinergic // traceable author statement /// 0009636 // response to toxin // traceable author statement /// 0043086 // negative regulation of catalytic activity // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003955 // NAD(P)H dehydrogenase (quinone) activity // traceable author statement /// 0003955 // NAD(P)H dehydrogenase (quinone) activity // inferred from electronic annotation /// 0004128 // cytochrome-b5 reductase activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201469_s_at AI809967 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI809967 /FEA=EST /DB_XREF=gi:5396533 /DB_XREF=est:wf64c03.x1 /CLONE=IMAGE:2360356 /UG=Hs.81972 SHC (Src homology 2 domain-containing) transforming protein 1 /FL=gb:NM_003029.1 gb:U73377.1 AI809967 SHC (Src homology 2 domain containing) transforming protein 1 SHC1 6464 NM_001130040 /// NM_001130041 /// NM_003029 /// NM_183001 0000165 // MAPKKK cascade // inferred from direct assay /// 0000165 // MAPKKK cascade // inferred from sequence or structural similarity /// 0000187 // activation of MAPK activity // inferred from direct assay /// 0000187 // activation of MAPK activity // inferred from sequence or structural similarity /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0007176 // regulation of epidermal growth factor receptor activity // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // not recorded /// 0007507 // heart development // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0016337 // cell-cell adhesion // inferred from electronic annotation /// 0031532 // actin cytoskeleton reorganization // inferred from electronic annotation /// 0045840 // positive regulation of mitosis // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from sequence or structural similarity 0005068 // transmembrane receptor protein tyrosine kinase adaptor protein activity // traceable author statement /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005543 // phospholipid binding // traceable author statement 201470_at NM_004832 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004832.1 /DEF=Homo sapiens glutathione-S-transferase like; glutathione transferase omega (GSTTLp28), mRNA. /FEA=mRNA /GEN=GSTTLp28 /PROD=glutathione-S-transferase like /DB_XREF=gi:4758483 /UG=Hs.11465 glutathione-S-transferase like; glutathione transferase omega /FL=gb:BC000127.1 gb:U90313.1 gb:NM_004832.1 gb:AF212303.1 NM_004832 glutathione S-transferase omega 1 GSTO1 9446 NM_004832 0008152 // metabolic process // inferred from electronic annotation /// 0019853 // L-ascorbic acid biosynthetic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement 0004364 // glutathione transferase activity // inferred from electronic annotation /// 0004364 // glutathione transferase activity // non-traceable author statement /// 0016656 // monodehydroascorbate reductase (NADH) activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation 201471_s_at NM_003900 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003900.1 /DEF=Homo sapiens sequestosome 1 (SQSTM1), mRNA. /FEA=mRNA /GEN=SQSTM1 /PROD=sequestosome 1 /DB_XREF=gi:4505570 /UG=Hs.182248 sequestosome 1 /FL=gb:U41806.1 gb:BC003139.1 gb:U46751.1 gb:NM_003900.1 NM_003900 sequestosome 1 SQSTM1 8878 NM_001142298 /// NM_001142299 /// NM_003900 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0008104 // protein localization // traceable author statement /// 0016197 // endosome transport // traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043122 // regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043122 // regulation of I-kappaB kinase/NF-kappaB cascade // inferred from sequence or structural similarity /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005829 // cytosol // non-traceable author statement /// 0005829 // cytosol // traceable author statement 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0030971 // receptor tyrosine kinase binding // traceable author statement /// 0042169 // SH2 domain binding // inferred from direct assay /// 0042169 // SH2 domain binding // inferred from sequence or structural similarity /// 0043130 // ubiquitin binding // inferred from direct assay /// 0043130 // ubiquitin binding // inferred from sequence or structural similarity /// 0046872 // metal ion binding // inferred from electronic annotation 201472_at NM_003372 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003372.2 /DEF=Homo sapiens von Hippel-Lindau binding protein 1 (VBP1), mRNA. /FEA=mRNA /GEN=VBP1 /PROD=von Hippel-Lindau binding protein 1 /DB_XREF=gi:9257253 /UG=Hs.198307 von Hippel-Lindau binding protein 1 /FL=gb:U96759.1 gb:NM_003372.2 NM_003372 von Hippel-Lindau binding protein 1 VBP1 7411 NM_003372 0006457 // protein folding // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016272 // prefoldin complex // inferred from electronic annotation 0005515 // protein binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from electronic annotation 201473_at NM_002229 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002229.1 /DEF=Homo sapiens jun B proto-oncogene (JUNB), mRNA. /FEA=mRNA /GEN=JUNB /PROD=jun B proto-oncogene /DB_XREF=gi:4504808 /UG=Hs.198951 jun B proto-oncogene /FL=gb:BC004250.1 gb:NM_002229.1 NM_002229 jun B proto-oncogene JUNB 3726 NM_002229 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001892 // embryonic placenta development // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0009987 // cellular process // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0046697 // decidualization // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation 0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003702 // RNA polymerase II transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046983 // protein dimerization activity // inferred from electronic annotation 201474_s_at NM_002204 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002204.1 /DEF=Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant a, mRNA. /FEA=mRNA /GEN=ITGA3 /PROD=integrin alpha 3 isoform a precursor /DB_XREF=gi:4504746 /UG=Hs.265829 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) /FL=gb:M59911.1 gb:NM_002204.1 NM_002204 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) ITGA3 3675 NM_002204 /// NM_005501 0001764 // neuron migration // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // traceable author statement /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0007613 // memory // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0008305 // integrin complex // traceable author statement /// 0008305 // integrin complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201475_x_at NM_004990 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004990.1 /DEF=Homo sapiens methionine-tRNA synthetase (MARS), mRNA. /FEA=mRNA /GEN=MARS /PROD=methionine-tRNA synthetase /DB_XREF=gi:4826825 /UG=Hs.279946 methionine-tRNA synthetase /FL=gb:BC002384.1 gb:NM_004990.1 gb:D84224.1 NM_004990 methionyl-tRNA synthetase MARS 4141 NM_004990 0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006431 // methionyl-tRNA aminoacylation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0000049 // tRNA binding // inferred from electronic annotation /// 0000166 // nucleotide binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004825 // methionine-tRNA ligase activity // traceable author statement /// 0004825 // methionine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201476_s_at AI692974 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI692974 /FEA=EST /DB_XREF=gi:4970314 /DB_XREF=est:wd36e03.x1 /CLONE=IMAGE:2330236 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1 AI692974 ribonucleotide reductase M1 RRM1 6240 NM_001033 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005971 // ribonucleoside-diphosphate reductase complex // non-traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity // non-traceable author statement /// 0004748 // ribonucleoside-diphosphate reductase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation 201477_s_at NM_001033 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001033.1 /DEF=Homo sapiens ribonucleotide reductase M1 polypeptide (RRM1), mRNA. /FEA=mRNA /GEN=RRM1 /PROD=ribonucleotide reductase M1 polypeptide /DB_XREF=gi:4506748 /UG=Hs.2934 ribonucleotide reductase M1 polypeptide /FL=gb:NM_001033.1 NM_001033 ribonucleotide reductase M1 RRM1 6240 NM_001033 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009263 // deoxyribonucleotide biosynthetic process // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005971 // ribonucleoside-diphosphate reductase complex // non-traceable author statement /// 0005971 // ribonucleoside-diphosphate reductase complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004748 // ribonucleoside-diphosphate reductase activity // non-traceable author statement /// 0004748 // ribonucleoside-diphosphate reductase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0017076 // purine nucleotide binding // inferred from electronic annotation 201478_s_at U59151 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U59151.1 /DEF=Human Cbf5p homolog (CBF5) mRNA, complete cds. /FEA=mRNA /GEN=CBF5 /PROD=Cbf5p homolog /DB_XREF=gi:2737893 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1 U59151 dyskeratosis congenita 1, dyskerin DKC1 1736 NM_001142463 /// NM_001363 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 201479_at NM_001363 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001363.1 /DEF=Homo sapiens dyskeratosis congenita 1, dyskerin (DKC1), mRNA. /FEA=mRNA /GEN=DKC1 /PROD=dyskeratosis congenita 1, dyskerin /DB_XREF=gi:4503336 /UG=Hs.4747 dyskeratosis congenita 1, dyskerin /FL=gb:U59151.1 gb:AF067008.1 gb:NM_001363.1 NM_001363 dyskeratosis congenita 1, dyskerin DKC1 1736 NM_001142463 /// NM_001363 0001522 // pseudouridine synthesis // inferred from electronic annotation /// 0006364 // rRNA processing // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0006396 // RNA processing // traceable author statement /// 0007004 // telomere maintenance via telomerase // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0042254 // ribosome biogenesis // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005697 // telomerase holoenzyme complex // inferred from direct assay /// 0005730 // nucleolus // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003720 // telomerase activity // inferred from direct assay /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0009982 // pseudouridine synthase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation 201480_s_at NM_003169 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003169.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 5 homolog (SUPT5H), mRNA. /FEA=mRNA /GEN=SUPT5H /PROD=suppressor of Ty (S.cerevisiae) 5 homolog /DB_XREF=gi:4507312 /UG=Hs.70186 suppressor of Ty (S.cerevisiae) 5 homolog /FL=gb:U56402.1 gb:AB000516.1 gb:NM_003169.1 NM_003169 suppressor of Ty 5 homolog (S. cerevisiae) SUPT5H 6829 NM_001111020 /// NM_001130824 /// NM_001130825 /// NM_003169 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // non-traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006354 // RNA elongation // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006368 // RNA elongation from RNA polymerase II promoter // inferred from direct assay /// 0007049 // cell cycle // non-traceable author statement /// 0010033 // response to organic substance // traceable author statement /// 0032968 // positive regulation of RNA elongation from RNA polymerase II promoter // inferred from electronic annotation /// 0045090 // retroviral genome replication // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded 0003711 // transcription elongation regulator activity // inferred from electronic annotation /// 0003746 // translation elongation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008148 // negative transcription elongation factor activity // inferred from direct assay /// 0008159 // positive transcription elongation factor activity // inferred from direct assay /// 0019899 // enzyme binding // inferred from physical interaction /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201481_s_at NM_002862 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002862.1 /DEF=Homo sapiens phosphorylase, glycogen; brain (PYGB), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PYGB /PROD=phosphorylase, glycogen; brain /DB_XREF=gi:4506350 /UG=Hs.75658 phosphorylase, glycogen; brain /FL=gb:U47025.1 gb:NM_002862.1 NM_002862 phosphorylase, glycogen; brain PYGB 5834 NM_002862 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0005977 // glycogen metabolic process // inferred from electronic annotation /// 0005980 // glycogen catabolic process // non-traceable author statement 0005737 // cytoplasm // inferred from direct assay 0003824 // catalytic activity // inferred from electronic annotation /// 0004645 // phosphorylase activity // inferred from electronic annotation /// 0008184 // glycogen phosphorylase activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 201482_at NM_002826 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002826.2 /DEF=Homo sapiens quiescin Q6 (QSCN6), mRNA. /FEA=mRNA /GEN=QSCN6 /PROD=quiescin Q6 /DB_XREF=gi:13325074 /UG=Hs.77266 quiescin Q6 /FL=gb:L42379.1 gb:U97276.2 gb:NM_002826.2 NM_002826 quiescin Q6 sulfhydryl oxidase 1 QSOX1 5768 NM_001004128 /// NM_002826 0006467 // protein thiol-disulfide exchange // inferred from genetic interaction /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030173 // integral to Golgi membrane // inferred from direct assay 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016971 // flavin-linked sulfhydryl oxidase activity // inferred from genetic interaction /// 0016972 // thiol oxidase activity // inferred from electronic annotation 201483_s_at BC002802 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002802.1 /DEF=Homo sapiens, suppressor of Ty (S.cerevisiae) 4 homolog 1, clone MGC:3864, mRNA, complete cds. /FEA=mRNA /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:12803910 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1 BC002802 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // RNA elongation from RNA polymerase II promoter // inferred from direct assay /// 0045941 // positive regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // not recorded 0003700 // transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008148 // negative transcription elongation factor activity // inferred from direct assay /// 0008159 // positive transcription elongation factor activity // inferred from direct assay /// 0008159 // positive transcription elongation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201484_at NM_003168 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003168.1 /DEF=Homo sapiens suppressor of Ty (S.cerevisiae) 4 homolog 1 (SUPT4H1), mRNA. /FEA=mRNA /GEN=SUPT4H1 /PROD=suppressor of Ty (S.cerevisiae) 4 homolog 1 /DB_XREF=gi:4507310 /UG=Hs.79058 suppressor of Ty (S.cerevisiae) 4 homolog 1 /FL=gb:BC002802.1 gb:U43923.1 gb:U38818.1 gb:U38817.1 gb:NM_003168.1 NM_003168 suppressor of Ty 4 homolog 1 (S. cerevisiae) SUPT4H1 6827 NM_003168 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0006338 // chromatin remodeling // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006368 // RNA elongation from RNA polymerase II promoter // inferred from direct assay /// 0045941 // positive regulation of transcription // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // not recorded 0003700 // transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008148 // negative transcription elongation factor activity // inferred from direct assay /// 0008159 // positive transcription elongation factor activity // inferred from direct assay /// 0008159 // positive transcription elongation factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201485_s_at BC004892 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC004892.1 /DEF=Homo sapiens, reticulocalbin 2, EF-hand calcium binding domain, clone MGC:1650, mRNA, complete cds. /FEA=mRNA /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:13436151 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1 BC004892 reticulocalbin 2, EF-hand calcium binding domain RCN2 5955 NM_002902 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // traceable author statement 201486_at NM_002902 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002902.1 /DEF=Homo sapiens reticulocalbin 2, EF-hand calcium binding domain (RCN2), mRNA. /FEA=mRNA /GEN=RCN2 /PROD=reticulocalbin 2, EF-hand calcium bindingdomain /DB_XREF=gi:4506456 /UG=Hs.79088 reticulocalbin 2, EF-hand calcium binding domain /FL=gb:BC004892.1 gb:NM_002902.1 NM_002902 reticulocalbin 2, EF-hand calcium binding domain RCN2 5955 NM_002902 0005783 // endoplasmic reticulum // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation 0005509 // calcium ion binding // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // traceable author statement 201487_at NM_001814 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001814.1 /DEF=Homo sapiens cathepsin C (CTSC), mRNA. /FEA=mRNA /GEN=CTSC /PROD=cathepsin C /DB_XREF=gi:4503140 /UG=Hs.10029 cathepsin C /FL=gb:NM_001814.1 NM_001814 cathepsin C CTSC 1075 NM_001114173 /// NM_001814 /// NM_148170 0006508 // proteolysis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement 0005764 // lysosome // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0031404 // chloride ion binding // inferred from electronic annotation 201488_x_at BC000717 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000717.1 /DEF=Homo sapiens, GAP-associated tyrosine phosphoprotein p62 (Sam68), clone MGC:1286, mRNA, complete cds. /FEA=mRNA /PROD=GAP-associated tyrosine phosphoprotein p62(Sam68) /DB_XREF=gi:12653852 /UG=Hs.119537 GAP-associated tyrosine phosphoprotein p62 (Sam68) /FL=gb:BC000717.1 gb:M88108.1 gb:NM_006559.1 BC000717 KH domain containing, RNA binding, signal transduction associated 1 KHDRBS1 10657 NM_006559 0000086 // G2/M transition of mitotic cell cycle // inferred from sequence or structural similarity /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007166 // cell surface receptor linked signal transduction // inferred from direct assay /// 0007166 // cell surface receptor linked signal transduction // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0016481 // negative regulation of transcription // inferred from sequence or structural similarity /// 0016481 // negative regulation of transcription // inferred from electronic annotation /// 0046831 // regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0046831 // regulation of RNA export from nucleus // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005070 // SH3/SH2 adaptor activity // inferred from physical interaction /// 0005070 // SH3/SH2 adaptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from sequence or structural similarity /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201489_at BC005020 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC005020.1 /DEF=Homo sapiens, peptidylprolyl isomerase F (cyclophilin F), clone MGC:11022, mRNA, complete cds. /FEA=mRNA /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:13477126 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1 BC005020 peptidylprolyl isomerase F PPIF 10105 NM_005729 0006457 // protein folding // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201490_s_at NM_005729 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005729.1 /DEF=Homo sapiens peptidylprolyl isomerase F (cyclophilin F) (PPIF), mRNA. /FEA=mRNA /GEN=PPIF /PROD=peptidylprolyl isomerase F (cyclophilin F) /DB_XREF=gi:5031986 /UG=Hs.173125 peptidylprolyl isomerase F (cyclophilin F) /FL=gb:BC005020.1 gb:M80254.1 gb:NM_005729.1 NM_005729 peptidylprolyl isomerase F PPIF 10105 NM_005729 0006457 // protein folding // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042277 // peptide binding // inferred from electronic annotation 201491_at NM_012111 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012111.1 /DEF=Homo sapiens chromosome 14 open reading frame 3 (C14ORF3), mRNA. /FEA=mRNA /GEN=C14ORF3 /PROD=chromosome 14 open reading frame 3 /DB_XREF=gi:6912279 /UG=Hs.204041 chromosome 14 open reading frame 3 /FL=gb:BC000321.1 gb:NM_012111.1 gb:AF164791.1 NM_012111 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) AHSA1 10598 NM_012111 0006457 // protein folding // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from sequence or structural similarity /// 0006950 // response to stress // inferred from electronic annotation 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0001671 // ATPase activator activity // inferred from sequence or structural similarity /// 0001671 // ATPase activator activity // inferred from electronic annotation /// 0001671 // ATPase activator activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0030189 // chaperone activator activity // inferred from sequence or structural similarity /// 0030189 // chaperone activator activity // inferred from electronic annotation /// 0051087 // chaperone binding // inferred from direct assay /// 0051087 // chaperone binding // inferred from electronic annotation 201492_s_at NM_021104 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021104.1 /DEF=Homo sapiens ribosomal protein L41 (RPL41), mRNA. /FEA=mRNA /GEN=RPL41 /PROD=ribosomal protein L41 /DB_XREF=gi:10863874 /UG=Hs.324406 ribosomal protein L41 /FL=gb:NM_021104.1 NM_021104 ribosomal protein L41 RPL41 6171 NM_001035267 /// NM_021104 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006414 // translational elongation // not recorded 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003735 // structural constituent of ribosome // traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 201493_s_at BE778078 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE778078 /FEA=EST /DB_XREF=gi:10199276 /DB_XREF=est:601463189F1 /CLONE=IMAGE:3866399 /UG=Hs.6151 pumilio (Drosophila) homolog 2 /FL=gb:AF315591.1 gb:NM_015317.1 BE778078 pumilio homolog 2 (Drosophila) PUM2 23369 NM_015317 0006417 // regulation of translation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201494_at NM_005040 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005040.1 /DEF=Homo sapiens prolylcarboxypeptidase (angiotensinase C) (PRCP), mRNA. /FEA=mRNA /GEN=PRCP /PROD=prolylcarboxypeptidase (angiotensinase C) /DB_XREF=gi:4826939 /UG=Hs.75693 prolylcarboxypeptidase (angiotensinase C) /FL=gb:L13977.1 gb:NM_005040.1 NM_005040 prolylcarboxypeptidase (angiotensinase C) PRCP 5547 NM_005040 /// NM_199418 0006508 // proteolysis // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004185 // serine-type carboxypeptidase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201495_x_at AI889739 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI889739 /FEA=EST /DB_XREF=gi:5594903 /DB_XREF=est:wo17e08.x1 /CLONE=IMAGE:2455622 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 AI889739 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0030241 // muscle thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0005859 // muscle myosin complex // traceable author statement /// 0005863 // striated muscle thick filament // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype 201496_x_at S67238 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:S67238.1 /DEF=smooth muscle myosin heavy chain isoform SM2 human, umbilical cord, fetal aorta, mRNA Partial, 1078 nt. /FEA=mRNA /GEN=smooth muscle myosin heavy chain isoform SM2 /PROD=smooth muscle myosin heavy chain isoform SM2 /DB_XREF=gi:452982 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 S67238 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0030241 // muscle thick filament assembly // inferred from sequence or structural similarity /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0005859 // muscle myosin complex // traceable author statement /// 0005863 // striated muscle thick filament // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype 201497_x_at NM_022844 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_022844.1 /DEF=Homo sapiens myosin, heavy polypeptide 11, smooth muscle (MYH11), transcript variant SM2, mRNA. /FEA=mRNA /GEN=MYH11 /PROD=smooth muscle myosin heavy chain 11, isoformSM2 /DB_XREF=gi:13124874 /UG=Hs.78344 myosin, heavy polypeptide 11, smooth muscle /FL=gb:NM_022844.1 NM_022844 myosin, heavy chain 11, smooth muscle MYH11 4629 NM_001040113 /// NM_001040114 /// NM_002474 /// NM_022844 0001501 // skeletal system development // traceable author statement /// 0006349 // genetic imprinting // traceable author statement /// 0006939 // smooth muscle contraction // inferred from sequence or structural similarity /// 0006941 // striated muscle contraction // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation /// 0008286 // insulin receptor signaling pathway // traceable author statement /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0030241 // muscle thick filament assembly // inferred from sequence or structural similarity /// 0032583 // regulation of gene-specific transcription // non-traceable author statement /// 0048251 // elastic fiber assembly // inferred from mutant phenotype /// 0048739 // cardiac muscle fiber development // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005859 // muscle myosin complex // traceable author statement /// 0005863 // striated muscle thick filament // inferred from electronic annotation /// 0016459 // myosin complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003774 // motor activity // inferred from electronic annotation /// 0003779 // actin binding // inferred from electronic annotation /// 0005158 // insulin receptor binding // inferred from physical interaction /// 0005159 // insulin-like growth factor receptor binding // inferred from electronic annotation /// 0005159 // insulin-like growth factor receptor binding // traceable author statement /// 0005179 // hormone activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008083 // growth factor activity // inferred from electronic annotation /// 0008307 // structural constituent of muscle // inferred from mutant phenotype 201498_at AI160440 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI160440 /FEA=EST /DB_XREF=gi:3693820 /DB_XREF=est:qc08f12.x1 /CLONE=IMAGE:1709039 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1 AI160440 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_003470 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201499_s_at NM_003470 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003470.1 /DEF=Homo sapiens ubiquitin specific protease 7 (herpes virus-associated) (USP7), mRNA. /FEA=mRNA /GEN=USP7 /PROD=ubiquitin specific protease 7 (herpesvirus-associated) /DB_XREF=gi:4507856 /UG=Hs.78683 ubiquitin specific protease 7 (herpes virus-associated) /FL=gb:NM_003470.1 NM_003470 ubiquitin specific peptidase 7 (herpes virus-associated) USP7 7874 NM_003470 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // inferred from mutant phenotype /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201500_s_at NM_021959 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021959.1 /DEF=Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA. /FEA=mRNA /GEN=PPP1R11 /PROD=protein phosphatase 1, regulatory (inhibitor)subunit 11 /DB_XREF=gi:11386174 /UG=Hs.82887 protein phosphatase 1, regulatory (inhibitor) subunit 11 /FL=gb:NM_021959.1 NM_021959 protein phosphatase 1, regulatory (inhibitor) subunit 11 PPP1R11 6992 NM_021959 0005625 // soluble fraction // traceable author statement 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201501_s_at NM_002092 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002092.1 /DEF=Homo sapiens G-rich RNA sequence binding factor 1 (GRSF1), mRNA. /FEA=mRNA /GEN=GRSF1 /PROD=G-rich RNA sequence binding factor 1 /DB_XREF=gi:4504160 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1 NM_002092 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 0006378 // mRNA polyadenylation // traceable author statement /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement 201502_s_at AI078167 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI078167 /FEA=EST /DB_XREF=gi:3412575 /DB_XREF=est:oz30d08.x1 /CLONE=IMAGE:1676847 /UG=Hs.81328 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha /FL=gb:NM_020529.1 gb:BC002601.1 gb:BC004983.1 gb:M69043.1 AI078167 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha NFKBIA 4792 NM_020529 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0006915 // apoptosis // traceable author statement /// 0007253 // cytoplasmic sequestering of NF-kappaB // non-traceable author statement /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032495 // response to muramyl dipeptide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0042345 // regulation of NF-kappaB import into nucleus // non-traceable author statement /// 0042994 // cytoplasmic sequestering of transcription factor // inferred from direct assay /// 0042994 // cytoplasmic sequestering of transcription factor // traceable author statement /// 0043330 // response to exogenous dsRNA // inferred from electronic annotation /// 0043392 // negative regulation of DNA binding // non-traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0045746 // negative regulation of Notch signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005829 // cytosol // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0008139 // nuclear localization sequence binding // inferred from physical interaction /// 0031625 // ubiquitin protein ligase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201503_at BG500067 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG500067 /FEA=EST /DB_XREF=gi:13461584 /DB_XREF=est:602545874F1 /CLONE=IMAGE:4668234 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1 BG500067 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201504_s_at AI435302 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI435302 /FEA=EST /DB_XREF=gi:4302230 /DB_XREF=est:ti02h06.x1 /CLONE=IMAGE:2129339 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI435302 translin TSN 7247 NM_004622 0006310 // DNA recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201505_at NM_002291 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002291.1 /DEF=Homo sapiens laminin, beta 1 (LAMB1), mRNA. /FEA=mRNA /GEN=LAMB1 /PROD=laminin, beta 1 precursor /DB_XREF=gi:4504950 /UG=Hs.82124 laminin, beta 1 /FL=gb:M61916.1 gb:NM_002291.1 NM_002291 laminin, beta 1 LAMB1 3912 NM_002291 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0031175 // neurite development // inferred from direct assay /// 0042476 // odontogenesis // inferred from direct assay /// 0050679 // positive regulation of epithelial cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from direct assay /// 0005604 // basement membrane // traceable author statement /// 0005604 // basement membrane // inferred from electronic annotation /// 0005606 // laminin-1 complex // inferred from direct assay /// 0005606 // laminin-1 complex // traceable author statement /// 0005607 // laminin-2 complex // inferred from direct assay /// 0005607 // laminin-2 complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0043257 // laminin-8 complex // inferred from direct assay /// 0043257 // laminin-8 complex // traceable author statement /// 0043259 // laminin-10 complex // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity 0005198 // structural molecule activity // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from direct assay /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 201506_at NM_000358 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000358.1 /DEF=Homo sapiens transforming growth factor, beta-induced, 68kD (TGFBI), mRNA. /FEA=mRNA /GEN=TGFBI /PROD=transforming growth factor, beta-induced, 68kD /DB_XREF=gi:4507466 /UG=Hs.118787 transforming growth factor, beta-induced, 68kD /FL=gb:BC000097.1 gb:BC004972.1 gb:M77349.1 gb:NM_000358.1 NM_000358 transforming growth factor, beta-induced, 68kDa TGFBI 7045 NM_000358 0007155 // cell adhesion // inferred from electronic annotation /// 0007162 // negative regulation of cell adhesion // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007601 // visual perception // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0050896 // response to stimulus // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005615 // extracellular space // inferred from electronic annotation 0005178 // integrin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201507_at NM_002622 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002622.2 /DEF=Homo sapiens prefoldin 1 (PFDN1), mRNA. /FEA=mRNA /GEN=PFDN1 /PROD=prefoldin 1 /DB_XREF=gi:12408673 /UG=Hs.132881 prefoldin 1 /FL=gb:NM_002622.2 NM_002622 prefoldin subunit 1 PFDN1 5201 NM_002622 0006457 // protein folding // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016272 // prefoldin complex // inferred from electronic annotation 0003700 // transcription factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0051082 // unfolded protein binding // inferred from electronic annotation 201508_at NM_001552 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001552.1 /DEF=Homo sapiens insulin-like growth factor-binding protein 4 (IGFBP4), mRNA. /FEA=mRNA /GEN=IGFBP4 /PROD=insulin-like growth factor-binding protein 4 /DB_XREF=gi:10835020 /UG=Hs.1516 insulin-like growth factor-binding protein 4 /FL=gb:NM_001552.1 gb:M62403.1 NM_001552 insulin-like growth factor binding protein 4 IGFBP4 3487 NM_001552 0001501 // skeletal system development // traceable author statement /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006259 // DNA metabolic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008283 // cell proliferation // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation 0005520 // insulin-like growth factor binding // inferred from electronic annotation /// 0019838 // growth factor binding // inferred from electronic annotation 201509_at NM_006899 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006899.1 /DEF=Homo sapiens isocitrate dehydrogenase 3 (NAD+) beta (IDH3B), mRNA. /FEA=mRNA /GEN=IDH3B /PROD=isocitrate dehydrogenase 3 (NAD+) beta /DB_XREF=gi:5901981 /UG=Hs.155410 isocitrate dehydrogenase 3 (NAD+) beta /FL=gb:BC001960.1 gb:U49283.1 gb:NM_006899.1 NM_006899 isocitrate dehydrogenase 3 (NAD+) beta IDH3B 3420 NM_006899 /// NM_174855 /// NM_174856 0006099 // tricarboxylic acid cycle // inferred from electronic annotation /// 0006102 // isocitrate metabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // not recorded 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004449 // isocitrate dehydrogenase (NAD+) activity // traceable author statement /// 0004449 // isocitrate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016616 // oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201510_at AF017307 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF017307.1 /DEF=Homo sapiens Ets-related transcription factor (ERT) mRNA, complete cds. /FEA=mRNA /GEN=ERT /PROD=Ets-related transcription factor /DB_XREF=gi:2338755 /UG=Hs.166096 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) /FL=gb:BC003569.1 gb:U66894.1 gb:U73843.1 gb:AF017307.1 gb:AF016295.1 gb:U97156.1 gb:NM_004433.1 AF017307 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) ELF3 1999 NM_001114309 /// NM_004433 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006954 // inflammatory response // inferred from expression pattern /// 0006954 // inflammatory response // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0008544 // epidermis development // non-traceable author statement /// 0009653 // anatomical structure morphogenesis // inferred from electronic annotation /// 0009790 // embryonic development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0060056 // mammary gland involution // inferred from electronic annotation /// 0060056 // mammary gland involution // inferred from sequence or structural similarity 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // non-traceable author statement /// 0003700 // transcription factor activity // traceable author statement /// 0003713 // transcription coactivator activity // inferred from direct assay /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016563 // transcription activator activity // inferred from direct assay /// 0016564 // transcription repressor activity // inferred from direct assay /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201511_at NM_001087 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001087.1 /DEF=Homo sapiens angio-associated, migratory cell protein (AAMP), mRNA. /FEA=mRNA /GEN=AAMP /PROD=angio-associated, migratory cell protein /DB_XREF=gi:4557228 /UG=Hs.83347 angio-associated, migratory cell protein /FL=gb:NM_001087.1 gb:M95627.1 NM_001087 angio-associated, migratory cell protein AAMP 14 NM_001087 0001525 // angiogenesis // non-traceable author statement /// 0001525 // angiogenesis // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0010595 // positive regulation of endothelial cell migration // inferred from sequence or structural similarity /// 0014909 // smooth muscle cell migration // inferred from expression pattern /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0008201 // heparin binding // traceable author statement 201512_s_at BC003633 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003633.1 /DEF=Homo sapiens, translocase of outer mitochondrial membrane 70 (yeast) homolog A, clone MGC:3766, mRNA, complete cds. /FEA=mRNA /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:13177705 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1 BC003633 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0043681 // protein import into mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201513_at AI659180 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI659180 /FEA=EST /DB_XREF=gi:4762750 /DB_XREF=est:tu02c06.x1 /CLONE=IMAGE:2249866 /UG=Hs.75066 translin /FL=gb:NM_004622.1 AI659180 translin TSN 7247 NM_004622 0006310 // DNA recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201514_s_at NM_005754 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005754.1 /DEF=Homo sapiens Ras-GTPase-activating protein SH3-domain-binding protein (G3BP), mRNA. /FEA=mRNA /GEN=G3BP /PROD=Ras-GTPase-activating protein SH3-domain-bindingprotein /DB_XREF=gi:5031702 /UG=Hs.220689 Ras-GTPase-activating protein SH3-domain-binding protein /FL=gb:U32519.1 gb:NM_005754.1 NM_005754 GTPase activating protein (SH3 domain) binding protein 1 G3BP1 10146 NM_005754 /// NM_198395 0006810 // transport // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004003 // ATP-dependent DNA helicase activity // traceable author statement /// 0004004 // ATP-dependent RNA helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201515_s_at NM_004622 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004622.1 /DEF=Homo sapiens translin (TSN), mRNA. /FEA=mRNA /GEN=TSN /PROD=translin /DB_XREF=gi:4759269 /UG=Hs.75066 translin /FL=gb:NM_004622.1 NM_004622 translin TSN 7247 NM_004622 0006310 // DNA recombination // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation 201516_at NM_003132 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003132.1 /DEF=Homo sapiens spermidine synthase (SRM), mRNA. /FEA=mRNA /GEN=SRM /PROD=spermidine synthase /DB_XREF=gi:4507208 /UG=Hs.76244 spermidine synthase /FL=gb:BC000309.1 gb:NM_003132.1 gb:M34338.1 NM_003132 spermidine synthase SRM 6723 NM_003132 0008295 // spermidine biosynthetic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004766 // spermidine synthase activity // traceable author statement /// 0004766 // spermidine synthase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201517_at BC001255 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001255.1 /DEF=Homo sapiens, nuclear cap binding protein subunit 2, 20kD, clone MGC:4991, mRNA, complete cds. /FEA=mRNA /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:12654824 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1 BC001255 nuclear cap binding protein subunit 2, 20kDa NCBP2 22916 NM_001042540 /// NM_007362 0000387 // spliceosomal snRNP biogenesis // not recorded /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0005845 // mRNA cap binding complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201518_at NM_006807 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006807.1 /DEF=Homo sapiens chromobox homolog 1 (Drosophila HP1 beta) (CBX1), mRNA. /FEA=mRNA /GEN=CBX1 /PROD=chromobox homolog 1 (Drosophila HP1 beta) /DB_XREF=gi:5803075 /UG=Hs.77254 chromobox homolog 1 (Drosophila HP1 beta) /FL=gb:U35451.1 gb:BC002609.1 gb:NM_006807.1 NM_006807 chromobox homolog 1 (HP1 beta homolog Drosophila ) CBX1 10951 NM_001127228 /// NM_006807 0006333 // chromatin assembly or disassembly // inferred from electronic annotation 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000785 // chromatin // inferred from direct assay /// 0000785 // chromatin // inferred from electronic annotation /// 0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005720 // nuclear heterochromatin // traceable author statement /// 0005721 // centromeric heterochromatin // inferred from electronic annotation /// 0005819 // spindle // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation 0003682 // chromatin binding // inferred from electronic annotation /// 0003682 // chromatin binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation 201519_at NM_014820 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014820.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 70 (yeast) homolog A (TOMM70A), mRNA. /FEA=mRNA /GEN=TOMM70A /PROD=translocase of outer mitochondrial membrane 70(yeast) homolog A /DB_XREF=gi:7662672 /UG=Hs.21198 translocase of outer mitochondrial membrane 70 (yeast) homolog A /FL=gb:BC003633.1 gb:AB018262.1 gb:NM_014820.1 NM_014820 translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) TOMM70A 9868 NM_014820 0043681 // protein import into mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008320 // protein transmembrane transporter activity // traceable author statement 201520_s_at BF034561 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF034561 /FEA=EST /DB_XREF=gi:10742273 /DB_XREF=est:601455476F1 /CLONE=IMAGE:3859242 /UG=Hs.79295 G-rich RNA sequence binding factor 1 /FL=gb:NM_002092.1 gb:U07231.1 BF034561 G-rich RNA sequence binding factor 1 GRSF1 2926 NM_001098477 /// NM_002092 0006378 // mRNA polyadenylation // traceable author statement /// 0009952 // anterior/posterior pattern formation // inferred from electronic annotation /// 0016331 // morphogenesis of embryonic epithelium // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003729 // mRNA binding // traceable author statement 201521_s_at NM_007362 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007362.1 /DEF=Homo sapiens nuclear cap binding protein subunit 2, 20kD (NCBP2), mRNA. /FEA=mRNA /GEN=NCBP2 /PROD=nuclear cap binding protein subunit 2, 20kD /DB_XREF=gi:6679063 /UG=Hs.240770 nuclear cap binding protein subunit 2, 20kD /FL=gb:D59253.1 gb:BC001255.1 gb:NM_007362.1 NM_007362 nuclear cap binding protein subunit 2, 20kDa NCBP2 22916 NM_001042540 /// NM_007362 0000387 // spliceosomal snRNP biogenesis // not recorded /// 0006408 // snRNA export from nucleus // inferred from sequence or structural similarity /// 0006408 // snRNA export from nucleus // non-traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from sequence or structural similarity /// 0046833 // positive regulation of RNA export from nucleus // inferred from sequence or structural similarity /// 0051028 // mRNA transport // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005829 // cytosol // not recorded /// 0005845 // mRNA cap binding complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from direct assay /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201522_x_at NM_003097 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003097.2 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1, mRNA. /FEA=mRNA /GEN=SNRPN /PROD=small nuclear ribonucleoprotein polypeptide N /DB_XREF=gi:13027651 /UG=Hs.48375 small nuclear ribonucleoprotein polypeptide N /FL=gb:U41303.1 gb:NM_003097.2 gb:BC003180.1 gb:J04615.1 NM_003097 small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame SNRPN /// SNURF 6638 /// 8926 NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 /// NR_001289 /// NR_001290 /// NR_001292 /// NR_001293 /// NR_001294 /// NR_001295 /// NR_003294 /// NR_003298 /// NR_003299 /// NR_003300 /// NR_003301 /// NR_003302 /// NR_003303 /// NR_003304 /// NR_003305 /// NR_003306 /// NR_003307 /// NR_003308 /// NR_003309 /// NR_003310 /// NR_003311 /// NR_003312 /// NR_003313 /// NR_003314 /// NR_003315 /// NR_003316 /// NR_003317 /// NR_003318 /// NR_003319 /// NR_003320 /// NR_003321 /// NR_003322 /// NR_003323 /// NR_003324 /// NR_003325 /// NR_003326 /// NR_003327 /// NR_003328 /// NR_003329 /// NR_003330 /// NR_003331 /// NR_003332 /// NR_003333 /// NR_003334 /// NR_003335 /// NR_003336 /// NR_003337 /// NR_003338 /// NR_003339 /// NR_003340 /// NR_003341 /// NR_003342 /// NR_003343 /// NR_003344 /// NR_003345 /// NR_003346 /// NR_003347 /// NR_003348 /// NR_003349 /// NR_003350 /// NR_003351 /// NR_003352 /// NR_003353 /// NR_003354 /// NR_003355 /// NR_003356 /// NR_003357 /// NR_003358 /// NR_003359 /// NR_003360 /// NR_003361 /// NR_003362 /// NR_003495 /// NR_003496 /// NR_003497 /// NR_003498 /// NR_003499 /// XM_001716451 /// XM_943028 0008380 // RNA splicing // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosome // traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation /// 0030532 // small nuclear ribonucleoprotein complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 201523_x_at BE262760 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE262760 /FEA=EST /DB_XREF=gi:9136144 /DB_XREF=est:601153762F1 /CLONE=IMAGE:3509895 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1 BE262760 ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) UBE2N 7334 NM_003348 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051443 // positive regulation of ubiquitin-protein ligase activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay 201524_x_at NM_003348 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003348.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) (UBE2N), mRNA. /FEA=mRNA /GEN=UBE2N /PROD=ubiquitin-conjugating enzyme E2N (homologous toyeast UBC13) /DB_XREF=gi:4507792 /UG=Hs.75355 ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13) /FL=gb:D83004.1 gb:BC000396.1 gb:BC003365.1 gb:NM_003348.1 NM_003348 ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) UBE2N 7334 NM_003348 0000724 // double-strand break repair via homologous recombination // inferred from mutant phenotype /// 0000729 // DNA double-strand break processing // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006282 // regulation of DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from mutant phenotype /// 0006464 // protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from mutant phenotype /// 0016567 // protein ubiquitination // traceable author statement /// 0016574 // histone ubiquitination // inferred from mutant phenotype /// 0031058 // positive regulation of histone modification // inferred from mutant phenotype /// 0033182 // regulation of histone ubiquitination // inferred from mutant phenotype /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0050852 // T cell receptor signaling pathway // inferred from mutant phenotype /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation /// 0051443 // positive regulation of ubiquitin-protein ligase activity // inferred from mutant phenotype 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0031372 // UBC13-MMS2 complex // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // inferred from direct assay 201525_at NM_001647 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001647.1 /DEF=Homo sapiens apolipoprotein D (APOD), mRNA. /FEA=mRNA /GEN=APOD /PROD=apolipoprotein D precursor /DB_XREF=gi:4502162 /UG=Hs.75736 apolipoprotein D /FL=gb:J02611.1 gb:NM_001647.1 NM_001647 apolipoprotein D APOD 347 NM_001647 0006629 // lipid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement 0005215 // transporter activity // inferred from electronic annotation /// 0005319 // lipid transporter activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005501 // retinoid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 201526_at NM_001662 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001662.2 /DEF=Homo sapiens ADP-ribosylation factor 5 (ARF5), mRNA. /FEA=mRNA /GEN=ARF5 /PROD=ADP-ribosylation factor 5 /DB_XREF=gi:6995999 /UG=Hs.77541 ADP-ribosylation factor 5 /FL=gb:BC003043.1 gb:M57567.1 gb:NM_001662.2 NM_001662 ADP-ribosylation factor 5 ARF5 381 NM_001662 0006810 // transport // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201527_at NM_004231 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004231.1 /DEF=Homo sapiens ATPase, vacuolar, 14 kD (ATP6S14), mRNA. /FEA=mRNA /GEN=ATP6S14 /PROD=ATPase, vacuolar, 14 kD /DB_XREF=gi:4757819 /UG=Hs.78089 ATPase, vacuolar, 14 kD /FL=gb:D49400.1 gb:NM_004231.1 NM_004231 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F ATP6V1F 9296 NM_004231 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0015986 // ATP synthesis coupled proton transport // inferred from electronic annotation /// 0015992 // proton transport // non-traceable author statement /// 0015992 // proton transport // inferred from electronic annotation 0005624 // membrane fraction // non-traceable author statement /// 0016469 // proton-transporting two-sector ATPase complex // non-traceable author statement /// 0033178 // proton-transporting two-sector ATPase complex, catalytic domain // inferred from electronic annotation /// 0033180 // proton-transporting V-type ATPase, V1 domain // inferred from electronic annotation 0015078 // hydrogen ion transmembrane transporter activity // inferred from electronic annotation /// 0015078 // hydrogen ion transmembrane transporter activity // non-traceable author statement /// 0042624 // ATPase activity, uncoupled // non-traceable author statement /// 0046933 // hydrogen ion transporting ATP synthase activity, rotational mechanism // inferred from electronic annotation /// 0046961 // proton-transporting ATPase activity, rotational mechanism // inferred from electronic annotation 201528_at BG398414 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG398414 /FEA=EST /DB_XREF=gi:13291862 /DB_XREF=est:602439888F1 /CLONE=IMAGE:4566380 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1 BG398414 replication protein A1, 70kDa RPA1 6117 NM_002945 0000718 // nucleotide-excision repair, DNA damage removal // not recorded /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded /// 0006310 // DNA recombination // traceable author statement /// 0007126 // meiosis // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005662 // DNA replication factor A complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201529_s_at NM_002945 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002945.1 /DEF=Homo sapiens replication protein A1 (70kD) (RPA1), mRNA. /FEA=mRNA /GEN=RPA1 /PROD=replication protein A1 (70kD) /DB_XREF=gi:4506582 /UG=Hs.84318 replication protein A1 (70kD) /FL=gb:M63488.1 gb:NM_002945.1 NM_002945 replication protein A1, 70kDa RPA1 6117 NM_002945 0000718 // nucleotide-excision repair, DNA damage removal // not recorded /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded /// 0006310 // DNA recombination // traceable author statement /// 0007126 // meiosis // inferred from electronic annotation 0000793 // condensed chromosome // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005662 // DNA replication factor A complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201530_x_at NM_001416 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001416.1 /DEF=Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA. /FEA=mRNA /GEN=EIF4A1 /PROD=eukaryotic translation initiation factor 4A,isoform 1 /DB_XREF=gi:4503528 /UG=Hs.129673 eukaryotic translation initiation factor 4A, isoform 1 /FL=gb:NM_001416.1 NM_001416 eukaryotic translation initiation factor 4A, isoform 1 EIF4A1 1973 NM_001416 0006412 // translation // inferred from electronic annotation 0005829 // cytosol // not recorded /// 0016281 // eukaryotic translation initiation factor 4F complex // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000339 // RNA cap binding // traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0004386 // helicase activity // traceable author statement /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation 201531_at NM_003407 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003407.1 /DEF=Homo sapiens zinc finger protein homologous to Zfp-36 in mouse (ZFP36), mRNA. /FEA=mRNA /GEN=ZFP36 /PROD=zinc finger protein homologous to Zfp-36 inmouse /DB_XREF=gi:4507960 /UG=Hs.1665 zinc finger protein homologous to Zfp-36 in mouse /FL=gb:M92843.1 gb:M63625.1 gb:NM_003407.1 NM_003407 zinc finger protein 36, C3H type, homolog (mouse) ZFP36 7538 NM_003407 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from electronic annotation /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0006402 // mRNA catabolic process // traceable author statement /// 0007243 // protein kinase cascade // inferred from electronic annotation /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003727 // single-stranded RNA binding // traceable author statement /// 0003729 // mRNA binding // inferred from direct assay /// 0003729 // mRNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0017091 // AU-rich element binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201532_at NM_002788 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002788.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 3 (PSMA3), mRNA. /FEA=mRNA /GEN=PSMA3 /PROD=proteasome (prosome, macropain) subunit, alphatype, 3 /DB_XREF=gi:4506182 /UG=Hs.167106 proteasome (prosome, macropain) subunit, alpha type, 3 /FL=gb:BC005265.1 gb:NM_002788.1 NM_002788 proteasome (prosome, macropain) subunit, alpha type, 3 PSMA3 5684 NM_002788 /// NM_152132 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201533_at NM_001904 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001904.1 /DEF=Homo sapiens catenin (cadherin-associated protein), beta 1 (88kD) (CTNNB1), mRNA. /FEA=mRNA /GEN=CTNNB1 /PROD=catenin (cadherin-associated protein), beta 1(88kD) /DB_XREF=gi:4503130 /UG=Hs.171271 catenin (cadherin-associated protein), beta 1 (88kD) /FL=gb:NM_001904.1 NM_001904 catenin (cadherin-associated protein), beta 1, 88kDa CTNNB1 1499 NM_001098209 /// NM_001098210 /// NM_001904 0001837 // epithelial to mesenchymal transition // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0016055 // Wnt receptor signaling pathway // inferred from direct assay /// 0016055 // Wnt receptor signaling pathway // inferred from electronic annotation /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-dependent // non-traceable author statement /// 0060070 // Wnt receptor signaling pathway through beta-catenin // inferred by curator 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0016328 // lateral plasma membrane // inferred from direct assay /// 0030877 // beta-catenin destruction complex // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0004871 // signal transducer activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0042301 // phosphate binding // inferred from sequence or structural similarity /// 0045296 // cadherin binding // inferred from physical interaction /// 0050681 // androgen receptor binding // non-traceable author statement 201534_s_at AF044221 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF044221.1 /DEF=Homo sapiens HCG-1 protein (HCG-1) mRNA, complete cds. /FEA=mRNA /GEN=HCG-1 /PROD=HCG-1 protein /DB_XREF=gi:4105251 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1 AF044221 ubiquitin-like 3 UBL3 5412 NM_007106 0006464 // protein modification process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201535_at NM_007106 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007106.1 /DEF=Homo sapiens ubiquitin-like 3 (UBL3), mRNA. /FEA=mRNA /GEN=UBL3 /PROD=ubiquitin-like 3 /DB_XREF=gi:6005927 /UG=Hs.173091 ubiquitin-like 3 /FL=gb:AF044221.1 gb:AL080177.1 gb:NM_007106.1 NM_007106 ubiquitin-like 3 UBL3 5412 NM_007106 0006464 // protein modification process // inferred from electronic annotation 0005622 // intracellular // inferred from direct assay /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 201536_at AL048503 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL048503 /FEA=EST /DB_XREF=gi:5936534 /DB_XREF=est:DKFZp586M1524_s1 /CLONE=DKFZp586M1524 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 AL048503 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation 0005654 // nucleoplasm // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // not recorded /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 201537_s_at BC002682 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002682.1 /DEF=Homo sapiens, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related), clone MGC:3615, mRNA, complete cds. /FEA=mRNA /PROD=dual specificity phosphatase 3 (vaccinia virusphosphatase VH1-related) /DB_XREF=gi:12803692 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 BC002682 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation 0005654 // nucleoplasm // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // not recorded /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 201538_s_at NM_004090 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004090.1 /DEF=Homo sapiens dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) (DUSP3), mRNA. /FEA=mRNA /GEN=DUSP3 /PROD=dual specificity phosphatase 3 /DB_XREF=gi:4758207 /UG=Hs.181046 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) /FL=gb:BC002682.1 gb:L05147.1 gb:NM_004090.1 NM_004090 dual specificity phosphatase 3 DUSP3 1845 NM_004090 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // traceable author statement /// 0016311 // dephosphorylation // inferred from electronic annotation 0005654 // nucleoplasm // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // not recorded /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0008138 // protein tyrosine/serine/threonine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation 201539_s_at U29538 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U29538.1 /DEF=Human heart protein with four and a half LIM domains (FHL-1) mRNA, complete cds. /FEA=mRNA /GEN=FHL-1 /DB_XREF=gi:2078479 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1 U29538 four and a half LIM domains 1 FHL1 2273 NM_001449 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201540_at NM_001449 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001449.1 /DEF=Homo sapiens four and a half LIM domains 1 (FHL1), mRNA. /FEA=mRNA /GEN=FHL1 /PROD=four and a half LIM domains 1 /DB_XREF=gi:4503720 /UG=Hs.239069 four and a half LIM domains 1 /FL=gb:U29538.1 gb:U60115.1 gb:NM_001449.1 NM_001449 four and a half LIM domains 1 FHL1 2273 NM_001449 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007517 // muscle development // non-traceable author statement /// 0009887 // organ morphogenesis // non-traceable author statement /// 0016049 // cell growth // non-traceable author statement /// 0030154 // cell differentiation // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201541_s_at NM_006349 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006349.1 /DEF=Homo sapiens putative cyclin G1 interacting protein (CG1I), mRNA. /FEA=mRNA /GEN=CG1I /PROD=putative cyclin G1 interacting protein /DB_XREF=gi:5453616 /UG=Hs.10028 putative cyclin G1 interacting protein /FL=gb:U61837.1 gb:NM_006349.1 NM_006349 zinc finger, HIT type 1 ZNHIT1 10467 NM_006349 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201542_at AY008268 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AY008268.1 /DEF=Homo sapiens GTP-binding protein SAR1 (SAR1) mRNA, complete cds. /FEA=mRNA /GEN=SAR1 /PROD=GTP-binding protein SAR1 /DB_XREF=gi:10445220 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1 AY008268 SAR1 homolog A (S. cerevisiae) SAR1A 56681 NM_001142648 /// NM_020150 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201543_s_at NM_020150 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_020150.1 /DEF=Homo sapiens SAR1 protein (SAR1), mRNA. /FEA=mRNA /GEN=SAR1 /PROD=SAR1 protein /DB_XREF=gi:9910541 /UG=Hs.110796 SAR1 protein /FL=gb:AY008268.1 gb:AL136724.1 gb:AF261717.1 gb:NM_020150.1 NM_020150 SAR1 homolog A (S. cerevisiae) SAR1A 56681 NM_001142648 /// NM_020150 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // non-traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016529 // sarcoplasmic reticulum // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // non-traceable author statement /// 0005525 // GTP binding // inferred from electronic annotation 201544_x_at BF675004 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF675004 /FEA=EST /DB_XREF=gi:11948899 /DB_XREF=est:602138088F1 /CLONE=IMAGE:4274564 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1 BF675004 poly(A) binding protein, nuclear 1 PABPN1 8106 NM_004643 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201545_s_at NM_004643 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004643.1 /DEF=Homo sapiens poly(A)-binding protein, nuclear 1 (PABPN1), mRNA. /FEA=mRNA /GEN=PABPN1 /PROD=poly(A)-binding protein, nuclear 1 /DB_XREF=gi:4758875 /UG=Hs.117176 poly(A)-binding protein, nuclear 1 /FL=gb:NM_004643.1 NM_004643 poly(A) binding protein, nuclear 1 PABPN1 8106 NM_004643 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006396 // RNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006936 // muscle contraction // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // not recorded /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201546_at NM_004238 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004238.1 /DEF=Homo sapiens thyroid hormone receptor interactor 12 (TRIP12), mRNA. /FEA=mRNA /GEN=TRIP12 /PROD=thyroid hormone receptor interactor 12 /DB_XREF=gi:10863902 /UG=Hs.138617 thyroid hormone receptor interactor 12 /FL=gb:NM_004238.1 gb:D28476.1 NM_004238 thyroid hormone receptor interactor 12 TRIP12 9320 NM_004238 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // non-traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // non-traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation /// 0046966 // thyroid hormone receptor binding // inferred from direct assay 201547_at AA729218 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA729218 /FEA=EST /DB_XREF=gi:2750577 /DB_XREF=est:nx35a04.s1 /CLONE=IMAGE:1258062 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 AA729218 jumonji, AT rich interactive domain 1B JARID1B 10765 NM_006618 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from direct assay /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201548_s_at W02593 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:W02593 /FEA=EST /DB_XREF=gi:1274571 /DB_XREF=est:za51e06.r1 /CLONE=IMAGE:296098 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 W02593 jumonji, AT rich interactive domain 1B JARID1B 10765 NM_006618 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from direct assay /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201549_x_at NM_006618 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006618.1 /DEF=Homo sapiens putative DNAchromatin binding motif (PLU-1), mRNA. /FEA=mRNA /GEN=PLU-1 /PROD=putative DNAchromatin binding motif /DB_XREF=gi:5729977 /UG=Hs.143323 putative DNAchromatin binding motif /FL=gb:NM_006618.1 NM_006618 jumonji, AT rich interactive domain 1B JARID1B 10765 NM_006618 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0005506 // iron ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from direct assay /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201550_x_at NM_001614 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001614.2 /DEF=Homo sapiens actin, gamma 1 (ACTG1), mRNA. /FEA=mRNA /GEN=ACTG1 /PROD=actin, gamma 1 propeptide /DB_XREF=gi:11038618 /UG=Hs.14376 actin, gamma 1 /FL=gb:NM_001614.2 gb:BC000292.1 NM_001614 actin, gamma 1 ACTG1 71 NM_001614 0006928 // cell motion // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from electronic annotation /// 0051592 // response to calcium ion // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0015629 // actin cytoskeleton // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // inferred by curator /// 0005200 // structural constituent of cytoskeleton // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201551_s_at J03263 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03263.1 /DEF=Human lysosome-associated membrane glycoprotein (lamp A) mRNA, complete cds. /FEA=mRNA /GEN=LAMP1 /DB_XREF=gi:187178 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 J03263 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0005624 // membrane fraction // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 201552_at NM_005561 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0005624 // membrane fraction // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 201553_s_at NM_005561 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005561.2 /DEF=Homo sapiens lysosomal-associated membrane protein 1 (LAMP1), mRNA. /FEA=mRNA /GEN=LAMP1 /PROD=lysosomal-associated membrane protein 1 /DB_XREF=gi:7669500 /UG=Hs.150101 lysosomal-associated membrane protein 1 /FL=gb:J04182.1 gb:J03263.1 gb:NM_005561.2 NM_005561 lysosomal-associated membrane protein 1 LAMP1 3916 NM_005561 0005624 // membrane fraction // traceable author statement /// 0005764 // lysosome // inferred from direct assay /// 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from electronic annotation /// 0005771 // multivesicular body // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 201554_x_at NM_004130 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004130.1 /DEF=Homo sapiens glycogenin (GYG), mRNA. /FEA=mRNA /GEN=GYG /PROD=glycogenin /DB_XREF=gi:4758491 /UG=Hs.174071 glycogenin /FL=gb:U44131.1 gb:BC000033.1 gb:NM_004130.1 gb:U31525.1 NM_004130 glycogenin 1 GYG1 2992 NM_004130 0005978 // glycogen biosynthetic process // inferred from electronic annotation 0005829 // cytosol // not recorded 0005515 // protein binding // inferred from physical interaction /// 0008466 // glycogenin glucosyltransferase activity // not recorded /// 0008466 // glycogenin glucosyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 201555_at NM_002388 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002388.2 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 3 (MCM3), mRNA. /FEA=mRNA /GEN=MCM3 /PROD=minichromosome maintenance deficient (S.cerevisiae) 3 /DB_XREF=gi:6631094 /UG=Hs.179565 minichromosome maintenance deficient (S. cerevisiae) 3 /FL=gb:BC001626.1 gb:NM_002388.2 gb:D38073.1 NM_002388 minichromosome maintenance complex component 3 MCM3 4172 NM_002388 0006260 // DNA replication // not recorded /// 0006260 // DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005658 // alpha DNA polymerase:primase complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201556_s_at BC002737 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002737.1 /DEF=Homo sapiens, vesicle-associated membrane protein 2, clone MGC:3377, mRNA, complete cds. /FEA=mRNA /PROD=vesicle-associated membrane protein 2 /DB_XREF=gi:12803794 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1 BC002737 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 0006944 // membrane fusion // inferred from electronic annotation /// 0016079 // synaptic vesicle exocytosis // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0017156 // calcium ion-dependent exocytosis // inferred from electronic annotation /// 0017157 // regulation of exocytosis // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0008021 // synaptic vesicle // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030141 // secretory granule // inferred from electronic annotation /// 0030672 // synaptic vesicle membrane // inferred from electronic annotation /// 0031201 // SNARE complex // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0042589 // zymogen granule membrane // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0000149 // SNARE binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005543 // phospholipid binding // inferred from electronic annotation /// 0017022 // myosin binding // inferred from electronic annotation /// 0017075 // syntaxin-1 binding // inferred from electronic annotation 201557_at NM_014232 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014232.1 /DEF=Homo sapiens vesicle-associated membrane protein 2 (synaptobrevin 2) (VAMP2), mRNA. /FEA=mRNA /GEN=VAMP2 /PROD=vesicle-associated membrane protein 2(synaptobrevin 2) /DB_XREF=gi:7657674 /UG=Hs.194534 vesicle-associated membrane protein 2 (synaptobrevin 2) /FL=gb:BC002737.1 gb:NM_014232.1 NM_014232 vesicle-associated membrane protein 2 (synaptobrevin 2) VAMP2 6844 NM_014232 0016192 // vesicle-mediated transport // inferred from electronic annotation 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019717 // synaptosome // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201558_at NM_003610 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003610.1 /DEF=Homo sapiens RAE1 (RNA export 1, S.pombe) homolog (RAE1), mRNA. /FEA=mRNA /GEN=RAE1 /PROD=RAE1 (RNA export 1, S.pombe) homolog /DB_XREF=gi:4506398 /UG=Hs.196209 RAE1 (RNA export 1, S.pombe) homolog /FL=gb:U84720.1 gb:NM_003610.1 NM_003610 RAE1 RNA export 1 homolog (S. pombe) RAE1 8480 NM_001015885 /// NM_003610 0006406 // mRNA export from nucleus // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005640 // nuclear outer membrane // traceable author statement /// 0005643 // nuclear pore // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0003723 // RNA binding // traceable author statement /// 0008017 // microtubule binding // inferred from sequence or structural similarity 201559_s_at AF109196 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF109196.1 /DEF=Homo sapiens intracellular chloride channel p64H1 mRNA, complete cds. /FEA=mRNA /PROD=intracellular chloride channel p64H1 /DB_XREF=gi:4588523 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1 AF109196 chloride intracellular channel 4 CLIC4 25932 NM_013943 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005625 // soluble fraction // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005902 // microvillus // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031404 // chloride ion binding // inferred from electronic annotation 201560_at NM_013943 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013943.1 /DEF=Homo sapiens chloride intracellular channel 4 (CLIC4), mRNA. /FEA=mRNA /GEN=CLIC4 /PROD=chloride intracellular channel 4 /DB_XREF=gi:7330334 /UG=Hs.25035 chloride intracellular channel 4 /FL=gb:AF109196.1 gb:AF097330.1 gb:AL117424.1 gb:NM_013943.1 NM_013943 chloride intracellular channel 4 CLIC4 25932 NM_013943 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // non-traceable author statement /// 0006821 // chloride transport // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030336 // negative regulation of cell migration // inferred from direct assay 0005622 // intracellular // inferred from direct assay /// 0005625 // soluble fraction // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005902 // microvillus // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0031404 // chloride ion binding // inferred from electronic annotation 201561_s_at NM_014944 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014944.1 /DEF=Homo sapiens KIAA0911 protein (KIAA0911), mRNA. /FEA=mRNA /GEN=KIAA0911 /PROD=KIAA0911 protein /DB_XREF=gi:7662373 /UG=Hs.29665 KIAA0911 protein /FL=gb:AB020718.1 gb:NM_014944.1 NM_014944 calsyntenin 1 CLSTN1 22883 NM_001009566 /// NM_014944 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201562_s_at NM_003104 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003104.1 /DEF=Homo sapiens sorbitol dehydrogenase (SORD), mRNA. /FEA=mRNA /GEN=SORD /PROD=sorbitol dehydrogenase /DB_XREF=gi:4507154 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1 NM_003104 sorbitol dehydrogenase SORD 6652 NM_003104 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005624 // membrane fraction // inferred from direct assay /// 0005625 // soluble fraction // inferred from direct assay /// 0005625 // soluble fraction // inferred from sequence or structural similarity /// 0005625 // soluble fraction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005529 // sugar binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay 201563_at L29008 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:L29008.1 /DEF=Human L-iditol-2 dehydrogenase mRNA, complete cds. /FEA=mRNA /PROD=L-iditol-2 dehydrogenase /DB_XREF=gi:496077 /UG=Hs.878 sorbitol dehydrogenase /FL=gb:NM_003104.1 gb:L29008.1 gb:U07361.1 L29008 sorbitol dehydrogenase SORD 6652 NM_003104 0006006 // glucose metabolic process // traceable author statement /// 0006060 // sorbitol metabolic process // inferred from electronic annotation /// 0006062 // sorbitol catabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0030317 // sperm motility // non-traceable author statement /// 0046370 // fructose biosynthetic process // inferred from direct assay /// 0051160 // L-xylitol catabolic process // inferred from direct assay /// 0051164 // L-xylitol metabolic process // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005615 // extracellular space // traceable author statement /// 0005624 // membrane fraction // inferred from direct assay /// 0005625 // soluble fraction // inferred from direct assay /// 0005625 // soluble fraction // inferred from sequence or structural similarity /// 0005625 // soluble fraction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from direct assay /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from sequence or structural similarity /// 0003939 // L-iditol 2-dehydrogenase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005529 // sugar binding // non-traceable author statement /// 0008270 // zinc ion binding // inferred from direct assay /// 0008270 // zinc ion binding // inferred from sequence or structural similarity /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0051287 // NAD binding // inferred from direct assay 201564_s_at NM_003088 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003088.1 /DEF=Homo sapiens singed (Drosophila)-like (sea urchin fascin homolog like) (SNL), mRNA. /FEA=mRNA /GEN=SNL /PROD=singed (Drosophila)-like (sea urchin fascinhomolog like) /DB_XREF=gi:4507114 /UG=Hs.118400 singed (Drosophila)-like (sea urchin fascin homolog like) /FL=gb:BC000521.1 gb:NM_003088.1 gb:U03057.1 gb:U09873.1 NM_003088 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) FSCN1 6624 NM_003088 0008283 // cell proliferation // traceable author statement /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0051017 // actin filament bundle formation // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0015629 // actin cytoskeleton // traceable author statement /// 0030175 // filopodium // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030674 // protein binding, bridging // inferred from electronic annotation /// 0051015 // actin filament binding // inferred from electronic annotation 201565_s_at NM_002166 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002166.1 /DEF=Homo sapiens inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2), mRNA. /FEA=mRNA /GEN=ID2 /PROD=inhibitor of DNA binding 2, dominant negativehelix-loop-helix protein /DB_XREF=gi:4504570 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1 NM_002166 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein ID2 3398 NM_002166 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043433 // negative regulation of transcription factor activity // inferred from direct assay /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from direct assay /// 0030528 // transcription regulator activity // inferred from electronic annotation 201566_x_at D13891 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D13891.1 /DEF=Human mRNA for Id-2H, complete cds. /FEA=mRNA /GEN=Id-2H /PROD=Id-2H /DB_XREF=gi:464183 /UG=Hs.180919 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /FL=gb:M97796.1 gb:NM_002166.1 gb:D13891.1 D13891 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein ID2 3398 NM_002166 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from direct assay /// 0043353 // enucleate erythrocyte differentiation // inferred from electronic annotation /// 0043433 // negative regulation of transcription factor activity // inferred from direct assay /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045651 // positive regulation of macrophage differentiation // inferred from electronic annotation 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016564 // transcription repressor activity // inferred from direct assay /// 0030528 // transcription regulator activity // inferred from electronic annotation 201567_s_at NM_002078 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002078.2 /DEF=Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA. /FEA=mRNA /GEN=GOLGA4 /PROD=golgi autoantigen, golgin subfamily a, 4 /DB_XREF=gi:6715599 /UG=Hs.183773 golgi autoantigen, golgin subfamily a, 4 /FL=gb:U41740.1 gb:NM_002078.2 NM_002078 golgi autoantigen, golgin subfamily a, 4 GOLGA4 2803 NM_002078 0016192 // vesicle-mediated transport // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005802 // trans-Golgi network // traceable author statement /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation 201568_at NM_014402 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014402.1 /DEF=Homo sapiens low molecular mass ubiquinone-binding protein (9.5kD) (QP-C), mRNA. /FEA=mRNA /GEN=QP-C /PROD=low molecular mass ubiquinone-binding protein /DB_XREF=gi:7657485 /UG=Hs.3709 low molecular mass ubiquinone-binding protein (9.5kD) /FL=gb:BC001390.1 gb:D50369.1 gb:NM_014402.1 NM_014402 ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa UQCRQ 27089 NM_014402 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0008121 // ubiquinol-cytochrome-c reductase activity // inferred from electronic annotation 201569_s_at NM_015380 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1 NM_015380 hypothetical protein LOC100131861 /// sorting and assembly machinery component 50 homolog (S. cerevisiae) LOC100131861 /// SAMM50 100131861 /// 25813 NM_015380 /// XM_001716418 /// XM_001724537 /// XM_001725780 0070096 // mitochondrial outer membrane translocase complex assembly // inferred from direct assay 0000299 // integral to membrane of membrane fraction // inferred from direct assay /// 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019867 // outer membrane // inferred from electronic annotation 201570_at NM_015380 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015380.1 /DEF=Homo sapiens CGI-51 protein (CGI-51), mRNA. /FEA=mRNA /GEN=CGI-51 /PROD=CGI-51 protein /DB_XREF=gi:7661541 /UG=Hs.4877 CGI-51 protein /FL=gb:AF151809.1 gb:NM_015380.1 NM_015380 sorting and assembly machinery component 50 homolog (S. cerevisiae) SAMM50 25813 NM_015380 0070096 // mitochondrial outer membrane translocase complex assembly // inferred from direct assay 0000299 // integral to membrane of membrane fraction // inferred from direct assay /// 0001401 // mitochondrial sorting and assembly machinery complex // inferred from mutant phenotype /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0019867 // outer membrane // inferred from electronic annotation 201571_s_at AI656493 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI656493 /FEA=EST /DB_XREF=gi:4740472 /DB_XREF=est:tt51d09.x1 /CLONE=IMAGE:2244305 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1 AI656493 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation 0005829 // cytosol // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0004132 // dCMP deaminase activity // traceable author statement /// 0004132 // dCMP deaminase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201572_x_at NM_001921 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001921.1 /DEF=Homo sapiens dCMP deaminase (DCTD), mRNA. /FEA=mRNA /GEN=DCTD /PROD=dCMP deaminase /DB_XREF=gi:4503276 /UG=Hs.76894 dCMP deaminase /FL=gb:L12136.1 gb:NM_001921.1 NM_001921 dCMP deaminase DCTD 1635 NM_001012732 /// NM_001921 0006220 // pyrimidine nucleotide metabolic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // inferred from electronic annotation 0005829 // cytosol // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004132 // dCMP deaminase activity // not recorded /// 0004132 // dCMP deaminase activity // traceable author statement /// 0004132 // dCMP deaminase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201573_s_at M75715 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M75715.1 /DEF=Human TB3-1 mRNA, complete cds. /FEA=mRNA /PROD=TB3-1 /DB_XREF=gi:338686 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1 M75715 eukaryotic translation termination factor 1 ETF1 2107 NM_004730 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation /// 0006449 // regulation of translational termination // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement 201574_at NM_004730 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004730.1 /DEF=Homo sapiens eukaryotic translation termination factor 1 (ETF1), mRNA. /FEA=mRNA /GEN=ETF1 /PROD=eukaryotic translation termination factor 1 /DB_XREF=gi:4759033 /UG=Hs.77324 eukaryotic translation termination factor 1 /FL=gb:U90176.1 gb:M75715.1 gb:NM_004730.1 NM_004730 eukaryotic translation termination factor 1 ETF1 2107 NM_004730 0006412 // translation // inferred from electronic annotation /// 0006415 // translational termination // inferred from electronic annotation /// 0006449 // regulation of translational termination // traceable author statement 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0003747 // translation release factor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008079 // translation termination factor activity // traceable author statement /// 0016149 // translation release factor activity, codon specific // inferred from electronic annotation /// 0043022 // ribosome binding // traceable author statement 201575_at NM_012245 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012245.1 /DEF=Homo sapiens SKI-INTERACTING PROTEIN (SNW1), mRNA. /FEA=mRNA /GEN=SNW1 /PROD=SKI-INTERACTING PROTEIN /DB_XREF=gi:6912675 /UG=Hs.79008 SKI-INTERACTING PROTEIN /FL=gb:U51432.1 gb:AF045184.1 gb:NM_012245.1 NM_012245 SNW domain containing 1 SNW1 22938 NM_012245 0000398 // nuclear mRNA splicing, via spliceosome // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006614 // SRP-dependent cotranslational protein targeting to membrane // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0016481 // negative regulation of transcription // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0048500 // signal recognition particle // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005112 // Notch binding // inferred from physical interaction /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005525 // GTP binding // inferred from electronic annotation /// 0008312 // 7S RNA binding // inferred from electronic annotation 201576_s_at NM_000404 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000404.1 /DEF=Homo sapiens galactosidase, beta 1 (GLB1), mRNA. /FEA=mRNA /GEN=GLB1 /PROD=galactosidase, beta 1 /DB_XREF=gi:10834965 /UG=Hs.79222 galactosidase, beta 1 /FL=gb:NM_000404.1 gb:M27507.1 gb:M22590.1 gb:M34423.1 NM_000404 galactosidase, beta 1 GLB1 2720 NM_000404 /// NM_001079811 /// NM_001135602 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005764 // lysosome // inferred from electronic annotation /// 0009341 // beta-galactosidase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004565 // beta-galactosidase activity // traceable author statement /// 0004565 // beta-galactosidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0043169 // cation binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201577_at NM_000269 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000269.1 /DEF=Homo sapiens non-metastatic cells 1, protein (NM23A) expressed in (NME1), mRNA. /FEA=mRNA /GEN=NME1 /PROD=non-metastatic cells 1 protein /DB_XREF=gi:4557796 /UG=Hs.118638 non-metastatic cells 1, protein (NM23A) expressed in /FL=gb:BC000293.1 gb:NM_000269.1 NM_000269 non-metastatic cells 1, protein (NM23A) expressed in /// non-metastatic cells 2, protein (NM23B) expressed in NME1 /// NME2 4830 /// 4831 NM_000269 /// NM_001018137 /// NM_001018138 /// NM_001018139 /// NM_002512 /// NM_198175 0006183 // GTP biosynthetic process // inferred from electronic annotation /// 0006228 // UTP biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007155 // cell adhesion // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009117 // nucleotide metabolic process // inferred from electronic annotation /// 0009142 // nucleoside triphosphate biosynthetic process // non-traceable author statement /// 0042981 // regulation of apoptosis // traceable author statement /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0043388 // positive regulation of DNA binding // inferred from direct assay /// 0045618 // positive regulation of keratinocyte differentiation // inferred from mutant phenotype /// 0045682 // regulation of epidermis development // inferred from mutant phenotype /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0050679 // positive regulation of epithelial cell proliferation // inferred from mutant phenotype 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred by curator /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0004536 // deoxyribonuclease activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from direct assay /// 0004550 // nucleoside diphosphate kinase activity // inferred from electronic annotation /// 0004550 // nucleoside diphosphate kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // non-traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201578_at NM_005397 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005397.1 /DEF=Homo sapiens podocalyxin-like (PODXL), mRNA. /FEA=mRNA /GEN=PODXL /PROD=podocalyxin-like /DB_XREF=gi:4885556 /UG=Hs.16426 podocalyxin-like /FL=gb:U97519.1 gb:NM_005397.1 NM_005397 podocalyxin-like PODXL 5420 NM_001018111 /// NM_005397 0007162 // negative regulation of cell adhesion // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation 201579_at NM_005245 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005245.1 /DEF=Homo sapiens FAT tumor suppressor (Drosophila) homolog (FAT), mRNA. /FEA=mRNA /GEN=FAT /PROD=FAT tumor suppressor precursor /DB_XREF=gi:4885228 /UG=Hs.166994 FAT tumor suppressor (Drosophila) homolog /FL=gb:NM_005245.1 NM_005245 FAT tumor suppressor homolog 1 (Drosophila) FAT1 2195 NM_005245 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation 201580_s_at AL544094 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL544094 /FEA=EST /DB_XREF=gi:12876573 /DB_XREF=est:AL544094 /CLONE=CS0DI004YG20 (3 prime) /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 AL544094 thioredoxin domain containing 13 TXNDC13 56255 NM_021156 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201581_at BF572868 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF572868 /FEA=EST /DB_XREF=gi:11646580 /DB_XREF=est:602079440F2 /CLONE=IMAGE:4254176 /UG=Hs.169358 hypothetical protein /FL=gb:NM_021156.1 BF572868 thioredoxin domain containing 13 TXNDC13 56255 NM_021156 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201582_at AL121900 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL121900 /DEF=Human DNA sequence from clone RP11-379J5 on chromosome 20 Contains the last exon of the SEC23B gene for Sec23 (S. cerevisiae) homolog B, a putative novel gene, the 5 end of the gene for a novel protein similar to bacterial histidyl-tRNA synthetas... /FEA=mRNA /DB_XREF=gi:11121203 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1 AL121900 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 201583_s_at NM_006363 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006363.1 /DEF=Homo sapiens Sec23 (S. cerevisiae) homolog B (SEC23B), mRNA. /FEA=mRNA /GEN=SEC23B /PROD=Sec23 (S. cerevisiae) homolog B /DB_XREF=gi:5454043 /UG=Hs.173497 Sec23 (S. cerevisiae) homolog B /FL=gb:BC005404.1 gb:NM_006363.1 NM_006363 Sec23 homolog B (S. cerevisiae) SEC23B 10483 NM_006363 /// NM_032985 /// NM_032986 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030127 // COPII vesicle coat // inferred from electronic annotation /// 0033116 // ER-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 201584_s_at NM_005804 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005804.1 /DEF=Homo sapiens nuclear RNA helicase, DECD variant of DEAD box family (DDXL), mRNA. /FEA=mRNA /GEN=DDXL /PROD=nuclear RNA helicase, DECD variant of DEAD boxfamily /DB_XREF=gi:5031658 /UG=Hs.179606 nuclear RNA helicase, DECD variant of DEAD box family /FL=gb:BC001009.1 gb:U90426.1 gb:NM_005804.1 NM_005804 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 DDX39 10212 NM_005804 0000398 // nuclear mRNA splicing, via spliceosome // inferred from genetic interaction /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from genetic interaction /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201585_s_at BG035151 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG035151 /FEA=EST /DB_XREF=gi:12428997 /DB_XREF=est:602324851F1 /CLONE=IMAGE:4412917 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1 BG035151 splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) SFPQ 6421 NM_005066 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201586_s_at NM_005066 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005066.1 /DEF=Homo sapiens splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) (SFPQ), mRNA. /FEA=mRNA /GEN=SFPQ /PROD=splicing factor prolineglutamine rich(polypyrimidine tract-binding protein-associated) /DB_XREF=gi:4826997 /UG=Hs.180610 splicing factor prolineglutamine rich (polypyrimidine tract-binding protein-associated) /FL=gb:NM_005066.1 NM_005066 splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) SFPQ 6421 NM_005066 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201587_s_at NM_001569 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001569.2 /DEF=Homo sapiens interleukin-1 receptor-associated kinase 1 (IRAK1), mRNA. /FEA=mRNA /GEN=IRAK1 /PROD=interleukin-1 receptor-associated kinase 1 /DB_XREF=gi:4755143 /UG=Hs.182018 interleukin-1 receptor-associated kinase 1 /FL=gb:L76191.1 gb:NM_001569.2 NM_001569 interleukin-1 receptor-associated kinase 1 IRAK1 3654 NM_001025242 /// NM_001025243 /// NM_001569 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007178 // transmembrane receptor protein serine/threonine kinase signaling pathway // non-traceable author statement /// 0007250 // activation of NF-kappaB-inducing kinase activity // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation /// 0031663 // lipopolysaccharide-mediated signaling pathway // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0045941 // positive regulation of transcription // non-traceable author statement /// 0046777 // protein amino acid autophosphorylation // non-traceable author statement /// 0051259 // protein oligomerization // inferred from mutant phenotype 0005829 // cytosol // not recorded /// 0045323 // interleukin-1 receptor complex // non-traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // non-traceable author statement /// 0004704 // NF-kappaB-inducing kinase activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005149 // interleukin-1 receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016563 // transcription activator activity // non-traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from sequence or structural similarity /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // non-traceable author statement 201588_at NM_004786 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004786.1 /DEF=Homo sapiens thioredoxin-like, 32kD (TXNL), mRNA. /FEA=mRNA /GEN=TXNL /PROD=thioredoxin-like, 32kD /DB_XREF=gi:4759273 /UG=Hs.18792 thioredoxin-like, 32kD /FL=gb:BC001156.1 gb:AF003938.1 gb:AF051896.1 gb:AF052659.1 gb:NM_004786.1 NM_004786 thioredoxin-like 1 TXNL1 9352 NM_004786 /// NR_024546 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0045454 // cell redox homeostasis // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0015036 // disulfide oxidoreductase activity // inferred from direct assay 201589_at D80000 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:D80000.1 /DEF=Human mRNA for KIAA0178 gene, partial cds. /FEA=mRNA /GEN=KIAA0178 /DB_XREF=gi:1136415 /UG=Hs.211602 SMC1 (structural maintenance of chromosomes 1, yeast)-like 1 /FL=gb:NM_006306.1 D80000 structural maintenance of chromosomes 1A SMC1A 8243 NM_006306 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0000075 // cell cycle checkpoint // inferred from direct assay /// 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006281 // DNA repair // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007052 // mitotic spindle organization // traceable author statement /// 0007064 // mitotic sister chromatid cohesion // traceable author statement /// 0007067 // mitosis // inferred from electronic annotation /// 0007126 // meiosis // inferred from sequence or structural similarity /// 0007126 // meiosis // inferred from electronic annotation /// 0009314 // response to radiation // inferred from expression pattern /// 0042770 // DNA damage response, signal transduction // inferred from direct assay /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0008280 // cohesin core heterodimer // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from direct assay /// 0003777 // microtubule motor activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201590_x_at NM_004039 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004039.1 /DEF=Homo sapiens annexin A2 (ANXA2), mRNA. /FEA=mRNA /GEN=ANXA2 /PROD=annexin A2 /DB_XREF=gi:4757755 /UG=Hs.217493 annexin A2 /FL=gb:BC001748.1 gb:D00017.1 gb:NM_004039.1 NM_004039 annexin A2 ANXA2 302 NM_001002857 /// NM_001002858 /// NM_001136015 /// NM_004039 0001501 // skeletal system development // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0005625 // soluble fraction // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0004859 // phospholipase inhibitor activity // inferred from electronic annotation /// 0004859 // phospholipase inhibitor activity // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005544 // calcium-dependent phospholipid binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201591_s_at NM_007184 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007184.1 /DEF=Homo sapiens imidazoline receptor candidate (I-1), mRNA. /FEA=mRNA /GEN=I-1 /PROD=imidazoline receptor candidate /DB_XREF=gi:6005787 /UG=Hs.26285 imidazoline receptor candidate /FL=gb:AF082516.1 gb:NM_007184.1 NM_007184 nischarin NISCH 11188 NM_007184 0006006 // glucose metabolic process // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007154 // cell communication // inferred from electronic annotation /// 0008217 // regulation of blood pressure // inferred from electronic annotation /// 0016601 // Rac protein signal transduction // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // inferred from electronic annotation /// 0030336 // negative regulation of cell migration // inferred from electronic annotation /// 0032228 // regulation of synaptic transmission, GABAergic // inferred from electronic annotation /// 0048243 // norepinephrine secretion // inferred from electronic annotation 0005624 // membrane fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0055037 // recycling endosome // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008227 // amine receptor activity // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation 201592_at NM_003756 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003756.1 /DEF=Homo sapiens eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) (EIF3S3), mRNA. /FEA=mRNA /GEN=EIF3S3 /PROD=eukaryotic translation initiation factor 3,subunit 3 (gamma, 40kD) /DB_XREF=gi:4503514 /UG=Hs.58189 eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) /FL=gb:BC000386.1 gb:U54559.1 gb:NM_003756.1 NM_003756 eukaryotic translation initiation factor 3, subunit H EIF3H 8667 NM_003756 0006412 // translation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // traceable author statement 0005829 // cytosol // not recorded /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008135 // translation factor activity, nucleic acid binding // traceable author statement 201593_s_at AV716798 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV716798 /FEA=EST /DB_XREF=gi:10813950 /DB_XREF=est:AV716798 /CLONE=DCBAKB02 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1 AV716798 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201594_s_at NM_005134 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005134.1 /DEF=Homo sapiens protein phosphatase 4, regulatory subunit 1 (PPP4R1), mRNA. /FEA=mRNA /GEN=PPP4R1 /PROD=protein phosphatase 4, regulatory subunit 1 /DB_XREF=gi:4826933 /UG=Hs.3382 protein phosphatase 4, regulatory subunit 1 /FL=gb:AF111106.1 gb:NM_005134.1 gb:AF100744.1 NM_005134 protein phosphatase 4, regulatory subunit 1 PPP4R1 9989 NM_001042388 /// NM_005134 0007165 // signal transduction // non-traceable author statement 0005625 // soluble fraction // non-traceable author statement 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0030362 // protein phosphatase type 4 regulator activity // non-traceable author statement 201595_s_at NM_018471 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018471.1 /DEF=Homo sapiens uncharacterized hypothalamus protein HT010 (HT010), mRNA. /FEA=mRNA /GEN=HT010 /PROD=uncharacterized hypothalamus protein HT010 /DB_XREF=gi:8923807 /UG=Hs.6375 uncharacterized hypothalamus protein HT010 /FL=gb:AF220184.1 gb:NM_018471.1 NM_018471 zinc finger CCCH-type containing 15 ZC3H15 55854 NM_018471 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201596_x_at NM_000224 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000224.1 /DEF=Homo sapiens keratin 18 (KRT18), mRNA. /FEA=mRNA /GEN=KRT18 /PROD=keratin 18 /DB_XREF=gi:4557887 /UG=Hs.65114 keratin 18 /FL=gb:BC000698.1 gb:BC000180.2 gb:BC004253.1 gb:M26326.1 gb:NM_000224.1 NM_000224 keratin 18 KRT18 3875 NM_000224 /// NM_199187 0006915 // apoptosis // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from electronic annotation /// 0043000 // Golgi to plasma membrane CFTR protein transport // inferred from direct assay /// 0043066 // negative regulation of apoptosis // inferred from direct assay /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from direct assay /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0034451 // centriolar satellite // inferred from direct assay /// 0045095 // keratin filament // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201597_at NM_001865 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001865.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (COX7A2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX7A2 /PROD=cytochrome c oxidase subunit VIIa polypeptide 2(liver) /DB_XREF=gi:4502988 /UG=Hs.70312 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) /FL=gb:NM_001865.1 NM_001865 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) COX7A2 1347 NM_001865 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation /// 0009055 // electron carrier activity // inferred from electronic annotation 201598_s_at NM_001567 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001567.2 /DEF=Homo sapiens inositol polyphosphate phosphatase-like 1 (INPPL1), mRNA. /FEA=mRNA /GEN=INPPL1 /PROD=inositol polyphosphate phosphatase-like 1 /DB_XREF=gi:4755141 /UG=Hs.75339 inositol polyphosphate phosphatase-like 1 /FL=gb:NM_001567.2 gb:L24444.1 NM_001567 inositol polyphosphate phosphatase-like 1 INPPL1 3636 NM_001567 0006796 // phosphate metabolic process // traceable author statement /// 0006955 // immune response // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0032957 // inositol trisphosphate metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0004437 // inositol or phosphatidylinositol phosphatase activity // non-traceable author statement /// 0004437 // inositol or phosphatidylinositol phosphatase activity // inferred from electronic annotation /// 0004445 // inositol-polyphosphate 5-phosphatase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005547 // phosphatidylinositol-3,4,5-triphosphate binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0017124 // SH3 domain binding // inferred from electronic annotation 201599_at NM_000274 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000274.1 /DEF=Homo sapiens ornithine aminotransferase (gyrate atrophy) (OAT), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=OAT /PROD=ornithine aminotransferase precursor /DB_XREF=gi:4557808 /UG=Hs.75485 ornithine aminotransferase (gyrate atrophy) /FL=gb:BC000964.1 gb:M12267.1 gb:M23204.1 gb:M14963.1 gb:NM_000274.1 NM_000274 ornithine aminotransferase (gyrate atrophy) OAT 4942 NM_000274 0007601 // visual perception // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005759 // mitochondrial matrix // non-traceable author statement /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004587 // ornithine-oxo-acid transaminase activity // traceable author statement /// 0004587 // ornithine-oxo-acid transaminase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008483 // transaminase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0030170 // pyridoxal phosphate binding // inferred from electronic annotation 201600_at NM_007273 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007273.1 /DEF=Homo sapiens B-cell associated protein (REA), mRNA. /FEA=mRNA /GEN=REA /PROD=B-cell associated protein /DB_XREF=gi:6005853 /UG=Hs.7771 B-cell associated protein /FL=gb:AF150962.1 gb:NM_007273.1 gb:AF126021.1 gb:AF178980.1 NM_007273 prohibitin 2 PHB2 11331 NM_007273 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016481 // negative regulation of transcription // non-traceable author statement 0005634 // nucleus // inferred from sequence or structural similarity /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0016566 // specific transcriptional repressor activity // inferred from direct assay /// 0030331 // estrogen receptor binding // non-traceable author statement 201601_x_at NM_003641 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003641.1 /DEF=Homo sapiens interferon induced transmembrane protein 1 (9-27) (IFITM1), mRNA. /FEA=mRNA /GEN=IFITM1 /PROD=interferon induced transmembrane protein 1(9-27) /DB_XREF=gi:4504580 /UG=Hs.146360 interferon induced transmembrane protein 1 (9-27) /FL=gb:BC000897.1 gb:J04164.1 gb:NM_003641.1 NM_003641 interferon induced transmembrane protein 1 (9-27) IFITM1 8519 NM_003641 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0009607 // response to biotic stimulus // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201602_s_at BE737620 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE737620 /FEA=EST /DB_XREF=gi:10151612 /DB_XREF=est:601572895F1 /CLONE=IMAGE:3839831 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 BE737620 protein phosphatase 1, regulatory (inhibitor) subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_002480 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201603_at AI817061 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI817061 /FEA=EST /DB_XREF=gi:5436140 /DB_XREF=est:wj76e05.x1 /CLONE=IMAGE:2408768 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 AI817061 protein phosphatase 1, regulatory (inhibitor) subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_002480 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201604_s_at NM_002480 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002480.1 /DEF=Homo sapiens myosin phosphatase, target subunit 1 (MYPT1), mRNA. /FEA=mRNA /GEN=MYPT1 /PROD=myosin phosphatase target subunit 1 /DB_XREF=gi:4505316 /UG=Hs.16533 myosin phosphatase, target subunit 1 /FL=gb:NM_002480.1 NM_002480 protein phosphatase 1, regulatory (inhibitor) subunit 12A PPP1R12A 4659 NM_001143885 /// NM_001143886 /// NM_002480 0005737 // cytoplasm // inferred from electronic annotation 0004871 // signal transducer activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201605_x_at NM_004368 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004368.1 /DEF=Homo sapiens calponin 2 (CNN2), mRNA. /FEA=mRNA /GEN=CNN2 /PROD=calponin 2 /DB_XREF=gi:4758017 /UG=Hs.169718 calponin 2 /FL=gb:D83735.1 gb:NM_004368.1 NM_004368 calponin 2 CNN2 1265 NM_004368 /// NM_201277 0007010 // cytoskeleton organization // traceable author statement /// 0031032 // actomyosin structure organization // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005911 // cell-cell junction // traceable author statement 0003779 // actin binding // traceable author statement /// 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // inferred from electronic annotation 201606_s_at BE796924 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE796924 /FEA=EST /DB_XREF=gi:10218031 /DB_XREF=est:601587284F1 /CLONE=IMAGE:3941445 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 BE796924 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006350 // transcription // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 201607_at AI694451 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI694451 /FEA=EST /DB_XREF=gi:4971791 /DB_XREF=est:wd83h06.x1 /CLONE=IMAGE:2338235 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 AI694451 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006350 // transcription // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 201608_s_at NM_007062 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007062.1 /DEF=Homo sapiens nuclear phosphoprotein similar to S. cerevisiae PWP1 (PWP1), mRNA. /FEA=mRNA /GEN=PWP1 /PROD=nuclear phosphoprotein similar to S. cerevisiaePWP1 /DB_XREF=gi:5902033 /UG=Hs.172589 nuclear phosphoprotein similar to S. cerevisiae PWP1 /FL=gb:BC001652.1 gb:L07758.1 gb:NM_007062.1 NM_007062 PWP1 homolog (S. cerevisiae) PWP1 11137 NM_007062 0006350 // transcription // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 201609_x_at AL578502 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL578502 /FEA=EST /DB_XREF=gi:12942638 /DB_XREF=est:AL578502 /CLONE=CS0DK011YK08 (3 prime) /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 AL578502 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // protein modification process // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003880 // C-terminal protein carboxyl methyltransferase activity // traceable author statement /// 0004671 // protein-S-isoprenylcysteine O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201610_at AF064084 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF064084.1 /DEF=Homo sapiens prenylcysteine carboxyl methyltransferase (PCCMT) mRNA, complete cds. /FEA=mRNA /GEN=PCCMT /PROD=prenylcysteine carboxyl methyltransferase /DB_XREF=gi:3135668 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 AF064084 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // protein modification process // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003880 // C-terminal protein carboxyl methyltransferase activity // traceable author statement /// 0004671 // protein-S-isoprenylcysteine O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201611_s_at NM_012405 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012405.1 /DEF=Homo sapiens isoprenylcysteine carboxyl methyltransferase (ICMT), mRNA. /FEA=mRNA /GEN=ICMT /PROD=isoprenylcysteine carboxyl methyltransferase /DB_XREF=gi:6912429 /UG=Hs.183212 isoprenylcysteine carboxyl methyltransferase /FL=gb:AF064084.1 gb:NM_012405.1 gb:AF173157.1 NM_012405 isoprenylcysteine carboxyl methyltransferase ICMT 23463 NM_012405 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0006464 // protein modification process // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // traceable author statement /// 0006481 // C-terminal protein amino acid methylation // inferred from electronic annotation /// 0006612 // protein targeting to membrane // traceable author statement /// 0008104 // protein localization // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0046578 // regulation of Ras protein signal transduction // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003880 // C-terminal protein carboxyl methyltransferase activity // traceable author statement /// 0004671 // protein-S-isoprenylcysteine O-methyltransferase activity // inferred from electronic annotation /// 0008140 // cAMP response element binding protein binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201612_at NM_000696 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000696.1 /DEF=Homo sapiens aldehyde dehydrogenase 9 (gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) (ALDH9), mRNA. /FEA=mRNA /GEN=ALDH9 /PROD=aldehyde dehydrogenase 9(gamma-aminobutyraldehyde dehydrogenase, E3 isozyme) /DB_XREF=gi:4502046 /UG=Hs.2533 aldehyde dehydrogenase 9 family, member A1 /FL=gb:U34252.1 gb:NM_000696.1 gb:AF172093.1 NM_000696 aldehyde dehydrogenase 9 family, member A1 ALDH9A1 223 NM_000696 0006081 // cellular aldehyde metabolic process // inferred from direct assay /// 0008152 // metabolic process // inferred from electronic annotation /// 0009437 // carnitine metabolic process // inferred from electronic annotation /// 0042136 // neurotransmitter biosynthetic process // inferred from direct assay /// 0042445 // hormone metabolic process // traceable author statement /// 0055114 // oxidation reduction // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from direct assay /// 0004029 // aldehyde dehydrogenase (NAD) activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016620 // oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor // inferred from electronic annotation /// 0019145 // aminobutyraldehyde dehydrogenase activity // inferred from direct assay /// 0019145 // aminobutyraldehyde dehydrogenase activity // inferred from electronic annotation /// 0047105 // 4-trimethylammoniobutyraldehyde dehydrogenase activity // inferred from electronic annotation 201613_s_at BC000519 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000519.1 /DEF=Homo sapiens, RuvB (E coli homolog)-like 1, clone MGC:8557, mRNA, complete cds. /FEA=mRNA /PROD=RuvB (E coli homolog)-like 1 /DB_XREF=gi:12653494 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1 BC000519 adaptor-related protein complex 1, gamma 2 subunit AP1G2 8906 NM_003917 /// NM_080545 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // non-traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // traceable author statement /// 0005798 // Golgi-associated vesicle // inferred from direct assay /// 0005798 // Golgi-associated vesicle // inferred from sequence or structural similarity /// 0005886 // plasma membrane // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0030117 // membrane coat // inferred from electronic annotation /// 0030121 // AP-1 adaptor complex // traceable author statement /// 0030131 // clathrin adaptor complex // inferred from electronic annotation /// 0030133 // transport vesicle // inferred from direct assay /// 0030133 // transport vesicle // inferred from sequence or structural similarity /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0044431 // Golgi apparatus part // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 201614_s_at NM_003707 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003707.1 /DEF=Homo sapiens RuvB (E coli homolog)-like 1 (RUVBL1), mRNA. /FEA=mRNA /GEN=RUVBL1 /PROD=TATA binding protein interacting protein 49 kDa /DB_XREF=gi:4506752 /UG=Hs.272822 RuvB (E coli homolog)-like 1 /FL=gb:BC000519.1 gb:BC002993.1 gb:AB012122.1 gb:AF070735.1 gb:AF099084.1 gb:NM_003707.1 NM_003707 RuvB-like 1 (E. coli) RUVBL1 8607 NM_003707 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007283 // spermatogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from electronic annotation /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0003678 // DNA helicase activity // inferred from direct assay /// 0003678 // DNA helicase activity // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from direct assay /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation 201615_x_at AI685060 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI685060 /FEA=EST /DB_XREF=gi:4896365 /DB_XREF=est:wc67a07.x1 /CLONE=IMAGE:2323668 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AI685060 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 0006928 // cell motion // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201616_s_at AL577531 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL577531 /FEA=EST /DB_XREF=gi:12940753 /DB_XREF=est:AL577531 /CLONE=CS0DI087YP20 (3 prime) /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 AL577531 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 0006928 // cell motion // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201617_x_at NM_004342 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004342.2 /DEF=Homo sapiens caldesmon 1 (CALD1), mRNA. /FEA=mRNA /GEN=CALD1 /PROD=caldesmon 1 /DB_XREF=gi:11091984 /UG=Hs.325474 caldesmon 1 /FL=gb:NM_004342.2 gb:M64110.1 NM_004342 caldesmon 1 CALD1 800 NM_004342 /// NM_033138 /// NM_033139 /// NM_033140 /// NM_033157 0006928 // cell motion // traceable author statement /// 0006936 // muscle contraction // inferred from electronic annotation 0005856 // cytoskeleton // traceable author statement /// 0005856 // cytoskeleton // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0003779 // actin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005523 // tropomyosin binding // traceable author statement /// 0017022 // myosin binding // inferred from electronic annotation 201618_x_at NM_003801 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003801.2 /DEF=Homo sapiens anchor attachment protein 1 (Gaa1p, yeast) homolog (GPAA1), mRNA. /FEA=mRNA /GEN=GPAA1 /PROD=anchor attachment protein 1 /DB_XREF=gi:6031166 /UG=Hs.4742 anchor attachment protein 1 (Gaa1p, yeast) homolog /FL=gb:BC003171.1 gb:BC004129.1 gb:AB006969.1 gb:AB002135.1 gb:NM_003801.2 NM_003801 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) GPAA1 8733 NM_003801 0006461 // protein complex assembly // non-traceable author statement /// 0006506 // GPI anchor biosynthetic process // inferred from electronic annotation /// 0006621 // protein retention in ER lumen // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // not recorded /// 0016255 // attachment of GPI anchor to protein // non-traceable author statement /// 0016255 // attachment of GPI anchor to protein // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0042765 // GPI-anchor transamidase complex // traceable author statement /// 0042765 // GPI-anchor transamidase complex // inferred from electronic annotation 0003923 // GPI-anchor transamidase activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0015631 // tubulin binding // non-traceable author statement /// 0034235 // GPI anchor binding // inferred from mutant phenotype 201619_at NM_006793 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006793.1 /DEF=Homo sapiens peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=PRDX3 /PROD=peroxiredoxin 3 /DB_XREF=gi:5802973 /UG=Hs.75454 peroxiredoxin 3 /FL=gb:BC002685.1 gb:NM_006793.1 gb:D49396.1 NM_006793 peroxiredoxin 3 PRDX3 10935 NM_006793 /// NM_014098 0006979 // response to oxidative stress // inferred from electronic annotation /// 0006979 // response to oxidative stress // inferred from mutant phenotype /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0030099 // myeloid cell differentiation // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0033673 // negative regulation of kinase activity // inferred from direct assay /// 0034614 // cellular response to reactive oxygen species // inferred from mutant phenotype /// 0042542 // response to hydrogen peroxide // inferred from direct assay /// 0042744 // hydrogen peroxide catabolic process // inferred from mutant phenotype /// 0042744 // hydrogen peroxide catabolic process // inferred from genetic interaction /// 0043066 // negative regulation of apoptosis // inferred from mutant phenotype /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051881 // regulation of mitochondrial membrane potential // inferred from mutant phenotype /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0008385 // IkappaB kinase complex // inferred from physical interaction 0004601 // peroxidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008022 // protein C-terminus binding // inferred from physical interaction /// 0008785 // alkyl hydroperoxide reductase activity // non-traceable author statement /// 0016209 // antioxidant activity // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0019900 // kinase binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from electronic annotation /// 0043027 // caspase inhibitor activity // inferred from mutant phenotype /// 0051920 // peroxiredoxin activity // inferred from electronic annotation 201620_at NM_003791 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003791.1 /DEF=Homo sapiens membrane-bound transcription factor protease, site 1 (MBTPS1), mRNA. /FEA=mRNA /GEN=MBTPS1 /PROD=site-1 protease preproprotein /DB_XREF=gi:4506774 /UG=Hs.75890 membrane-bound transcription factor protease, site 1 /FL=gb:NM_003791.1 gb:D42053.1 NM_003791 membrane-bound transcription factor peptidase, site 1 MBTPS1 8720 NM_003791 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0042990 // regulation of transcription factor import into nucleus // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005788 // endoplasmic reticulum lumen // traceable author statement /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // traceable author statement /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201621_at NM_005380 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005380.1 /DEF=Homo sapiens neuroblastoma, suppression of tumorigenicity 1 (NBL1), mRNA. /FEA=mRNA /GEN=NBL1 /PROD=neuroblastoma, suppression of tumorigenicity 1 /DB_XREF=gi:4885508 /UG=Hs.76307 neuroblastoma, suppression of tumorigenicity 1 /FL=gb:NM_005380.1 gb:D28124.1 NM_005380 neuroblastoma, suppression of tumorigenicity 1 NBL1 4681 NM_005380 /// NM_182744 0007049 // cell cycle // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 201622_at NM_014390 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014390.1 /DEF=Homo sapiens EBNA-2 co-activator (100kD) (p100), mRNA. /FEA=mRNA /GEN=p100 /PROD=EBNA-2 co-activator (100kD) /DB_XREF=gi:7657430 /UG=Hs.79093 EBNA-2 co-activator (100kD) /FL=gb:NM_014390.1 gb:U22055.1 NM_014390 staphylococcal nuclease and tudor domain containing 1 SND1 27044 NM_014390 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016246 // RNA interference // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016442 // RNA-induced silencing complex // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003712 // transcription cofactor activity // traceable author statement /// 0004518 // nuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016788 // hydrolase activity, acting on ester bonds // inferred from electronic annotation 201623_s_at BC000629 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000629.1 /DEF=Homo sapiens, Similar to aspartyl-tRNA synthetase, clone MGC:1562, mRNA, complete cds. /FEA=mRNA /PROD=Similar to aspartyl-tRNA synthetase /DB_XREF=gi:12653688 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1 BC000629 aspartyl-tRNA synthetase DARS 1615 NM_001349 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006422 // aspartyl-tRNA aminoacylation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // traceable author statement /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201624_at NM_001349 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001349.1 /DEF=Homo sapiens aspartyl-tRNA synthetase (DARS), mRNA. /FEA=mRNA /GEN=DARS /PROD=aspartyl-tRNA synthetase /DB_XREF=gi:4557512 /UG=Hs.80758 aspartyl-tRNA synthetase /FL=gb:BC000629.1 gb:J05032.1 gb:NM_001349.1 NM_001349 aspartyl-tRNA synthetase DARS 1615 NM_001349 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006422 // aspartyl-tRNA aminoacylation // traceable author statement /// 0006422 // aspartyl-tRNA aminoacylation // inferred from electronic annotation /// 0006461 // protein complex assembly // traceable author statement 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004046 // aminoacylase activity // traceable author statement /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004815 // aspartate-tRNA ligase activity // traceable author statement /// 0004815 // aspartate-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation 201625_s_at BE300521 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE300521 /FEA=EST /DB_XREF=gi:9184269 /DB_XREF=est:ba69f11.x1 /CLONE=IMAGE:2905677 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BE300521 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201626_at BG292233 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG292233 /FEA=EST /DB_XREF=gi:13050848 /DB_XREF=est:602386668F1 /CLONE=IMAGE:4515521 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 BG292233 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201627_s_at NM_005542 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005542.1 /DEF=Homo sapiens insulin induced gene 1 (INSIG1), mRNA. /FEA=mRNA /GEN=INSIG1 /PROD=insulin induced gene 1 /DB_XREF=gi:5031800 /UG=Hs.56205 insulin induced gene 1 /FL=gb:NM_005542.1 NM_005542 insulin induced gene 1 INSIG1 3638 NM_005542 /// NM_198336 /// NM_198337 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201628_s_at NM_006570 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006570.1 /DEF=Homo sapiens Ras-related GTP-binding protein (RAGA), mRNA. /FEA=mRNA /GEN=RAGA /PROD=Ras-related GTP-binding protein /DB_XREF=gi:5729998 /UG=Hs.57304 Ras-related GTP-binding protein /FL=gb:U41654.1 gb:NM_006570.1 NM_006570 Ras-related GTP binding A RRAGA 10670 NM_006570 0006915 // apoptosis // inferred from electronic annotation /// 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0008219 // cell death // inferred from direct assay /// 0008219 // cell death // traceable author statement /// 0019048 // virus-host interaction // inferred from direct assay /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045919 // positive regulation of cytolysis // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005794 // Golgi apparatus // inferred from direct assay /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement /// 0005525 // GTP binding // inferred from direct assay /// 0005525 // GTP binding // inferred from electronic annotation /// 0005525 // GTP binding // traceable author statement /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0051219 // phosphoprotein binding // inferred from direct assay 201629_s_at BE872974 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE872974 /FEA=EST /DB_XREF=gi:10321660 /DB_XREF=est:601450667F1 /CLONE=IMAGE:3854584 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1 BE872974 acid phosphatase 1, soluble ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NR_024080 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003993 // acid phosphatase activity // traceable author statement /// 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201630_s_at NM_004300 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004300.1 /DEF=Homo sapiens acid phosphatase 1, soluble (ACP1), transcript variant a, mRNA. /FEA=mRNA /GEN=ACP1 /PROD=acid phosphatase 1 isoform a /DB_XREF=gi:4757713 /UG=Hs.75393 acid phosphatase 1, soluble /FL=gb:M83653.1 gb:NM_004300.1 NM_004300 acid phosphatase 1, soluble ACP1 52 NM_001040649 /// NM_004300 /// NM_007099 /// NR_024080 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003993 // acid phosphatase activity // traceable author statement /// 0003993 // acid phosphatase activity // inferred from electronic annotation /// 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004726 // non-membrane spanning protein tyrosine phosphatase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016791 // phosphatase activity // inferred from electronic annotation /// 0042802 // identical protein binding // inferred from physical interaction 201631_s_at NM_003897 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003897.1 /DEF=Homo sapiens immediate early response 3 (IER3), mRNA. /FEA=mRNA /GEN=IER3 /PROD=immediate early response 3 /DB_XREF=gi:4503328 /UG=Hs.76095 immediate early response 3 /FL=gb:BC000844.1 gb:BC005080.1 gb:AF083421.1 gb:NM_003897.1 NM_003897 immediate early response 3 IER3 8870 NM_003897 0006915 // apoptosis // traceable author statement /// 0006916 // anti-apoptosis // non-traceable author statement /// 0006916 // anti-apoptosis // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201632_at NM_001414 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001414.1 /DEF=Homo sapiens eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) (EIF2B1), mRNA. /FEA=mRNA /GEN=EIF2B1 /PROD=eukaryotic translation initiation factor 2B,subunit 1 (alpha, 26kD) /DB_XREF=gi:4503502 /UG=Hs.78592 eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) /FL=gb:NM_001414.1 NM_001414 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa EIF2B1 1967 NM_001414 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from direct assay /// 0009408 // response to heat // inferred from sequence or structural similarity /// 0009408 // response to heat // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation /// 0009749 // response to glucose stimulus // inferred from sequence or structural similarity /// 0009749 // response to glucose stimulus // inferred from electronic annotation /// 0014003 // oligodendrocyte development // inferred from mutant phenotype /// 0043434 // response to peptide hormone stimulus // inferred from sequence or structural similarity /// 0043434 // response to peptide hormone stimulus // inferred from electronic annotation /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0051716 // cellular response to stimulus // inferred from direct assay 0005624 // membrane fraction // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005851 // eukaryotic translation initiation factor 2B complex // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay 0003743 // translation initiation factor activity // inferred from direct assay /// 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201633_s_at AW235051 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW235051 /FEA=EST /DB_XREF=gi:6567440 /DB_XREF=est:xn18a09.x1 /CLONE=IMAGE:2694040 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1 AW235051 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201634_s_at NM_030579 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_030579.1 /DEF=Homo sapiens cytochrome b5 outer mitochondrial membrane precursor (CYB5-M), mRNA. /FEA=mRNA /GEN=CYB5-M /PROD=cytochrome b5 outer mitochondrial membraneprecursor /DB_XREF=gi:13385593 /UG=Hs.79103 cytochrome b5 outer mitochondrial membrane precursor /FL=gb:BC004373.1 gb:NM_030579.1 NM_030579 cytochrome b5 type B (outer mitochondrial membrane) CYB5B 80777 NM_030579 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201635_s_at AI990766 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI990766 /FEA=EST /DB_XREF=gi:5837647 /DB_XREF=est:ws23e06.x1 /CLONE=IMAGE:2498050 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 AI990766 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 0006915 // apoptosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201636_at BG025078 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG025078 /FEA=EST /DB_XREF=gi:12411309 /DB_XREF=est:602276425F1 /CLONE=IMAGE:4364070 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 BG025078 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 0006915 // apoptosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201637_s_at NM_005087 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005087.1 /DEF=Homo sapiens fragile X mental retardation, autosomal homolog 1 (FXR1), mRNA. /FEA=mRNA /GEN=FXR1 /PROD=fragile X mental retardation-related protein 1 /DB_XREF=gi:4826735 /UG=Hs.82712 fragile X mental retardation, autosomal homolog 1 /FL=gb:NM_005087.1 gb:U25165.1 NM_005087 fragile X mental retardation, autosomal homolog 1 FXR1 8087 NM_001013438 /// NM_001013439 /// NM_005087 0006915 // apoptosis // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007519 // skeletal muscle development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005730 // nucleolus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005844 // polysome // traceable author statement 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation 201638_s_at BE676642 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE676642 /FEA=EST /DB_XREF=gi:10037183 /DB_XREF=est:7f33f02.x1 /CLONE=IMAGE:3296475 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1 BE676642 cleavage and polyadenylation specific factor 1, 160kDa CPSF1 29894 NM_013291 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201639_s_at NM_013291 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013291.1 /DEF=Homo sapiens cleavage and polyadenylation specific factor 1, 160kD subunit (CPSF1), mRNA. /FEA=mRNA /GEN=CPSF1 /PROD=cleavage and polyadenylation specific factor 1,160kD subunit /DB_XREF=gi:9558724 /UG=Hs.83727 cleavage and polyadenylation specific factor 1, 160kD subunit /FL=gb:U37012.1 gb:AB046744.1 gb:NM_013291.1 NM_013291 cleavage and polyadenylation specific factor 1, 160kDa CPSF1 29894 NM_013291 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006378 // mRNA polyadenylation // inferred from direct assay /// 0006379 // mRNA cleavage // inferred from direct assay /// 0006397 // mRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005847 // mRNA cleavage and polyadenylation specificity factor complex // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003730 // mRNA 3'-UTR binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction 201640_x_at NM_001294 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001294.1 /DEF=Homo sapiens cleft lip and palate associated transmembrane protein 1 (CLPTM1), mRNA. /FEA=mRNA /GEN=CLPTM1 /PROD=cleft lip and palate associated transmembraneprotein 1 /DB_XREF=gi:4502896 /UG=Hs.106671 cleft lip and palate associated transmembrane protein 1 /FL=gb:AF037339.1 gb:NM_001294.1 NM_001294 cleft lip and palate associated transmembrane protein 1 CLPTM1 1209 NM_001294 0007275 // multicellular organismal development // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0033081 // regulation of T cell differentiation in the thymus // inferred from sequence or structural similarity 0005887 // integral to plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201641_at NM_004335 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004335.2 /DEF=Homo sapiens bone marrow stromal cell antigen 2 (BST2), mRNA. /FEA=mRNA /GEN=BST2 /PROD=bone marrow stromal cell antigen 2 /DB_XREF=gi:7262372 /UG=Hs.118110 bone marrow stromal cell antigen 2 /FL=gb:D28137.1 gb:NM_004335.2 NM_004335 bone marrow stromal cell antigen 2 BST2 684 NM_004335 0006959 // humoral immune response // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement /// 0007275 // multicellular organismal development // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0042113 // B cell activation // inferred from electronic annotation /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0031225 // anchored to membrane // inferred from electronic annotation 0004871 // signal transducer activity // inferred from mutant phenotype 201642_at NM_005534 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005534.1 /DEF=Homo sapiens interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2), mRNA. /FEA=mRNA /GEN=IFNGR2 /PROD=interferon gamma receptor 2 (interferon gammatransducer 1) /DB_XREF=gi:5031782 /UG=Hs.177559 interferon gamma receptor 2 (interferon gamma transducer 1) /FL=gb:BC003624.1 gb:U05875.1 gb:U05877.1 gb:NM_005534.1 NM_005534 interferon gamma receptor 2 (interferon gamma transducer 1) IFNGR2 3460 NM_005534 0007166 // cell surface receptor linked signal transduction // traceable author statement /// 0009615 // response to virus // traceable author statement 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004906 // interferon-gamma receptor activity // traceable author statement 201643_x_at NM_016604 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016604.1 /DEF=Homo sapiens putative zinc finger protein (LOC51780), mRNA. /FEA=mRNA /GEN=LOC51780 /PROD=putative zinc finger protein /DB_XREF=gi:7706598 /UG=Hs.24125 putative zinc finger protein /FL=gb:AF251039.1 gb:NM_016604.1 NM_016604 jumonji domain containing 1B JMJD1B 51780 NM_016604 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0005506 // iron ion binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016702 // oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201644_at NM_003313 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003313.2 /DEF=Homo sapiens tissue specific transplantation antigen P35B (TSTA3), mRNA. /FEA=mRNA /GEN=TSTA3 /PROD=tissue specific transplantation antigen P35B /DB_XREF=gi:6598326 /UG=Hs.264428 tissue specific transplantation antigen P35B /FL=gb:BC001941.1 gb:U58766.1 gb:NM_003313.2 NM_003313 tissue specific transplantation antigen P35B TSTA3 7264 NM_003313 0007159 // leukocyte adhesion // non-traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009225 // nucleotide-sugar metabolic process // traceable author statement /// 0019835 // cytolysis // inferred from electronic annotation /// 0042351 // 'de novo' GDP-L-fucose biosynthetic process // traceable author statement /// 0044237 // cellular metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005737 // cytoplasm // inferred by curator 0003824 // catalytic activity // inferred from electronic annotation /// 0003824 // catalytic activity // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0009055 // electron carrier activity // traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016853 // isomerase activity // inferred from electronic annotation /// 0042356 // GDP-4-dehydro-D-rhamnose reductase activity // traceable author statement /// 0050577 // GDP-L-fucose synthase activity // inferred from electronic annotation /// 0050662 // coenzyme binding // inferred from electronic annotation 201645_at NM_002160 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002160.1 /DEF=Homo sapiens hexabrachion (tenascin C, cytotactin) (HXB), mRNA. /FEA=mRNA /GEN=HXB /PROD=hexabrachion (tenascin C, cytotactin) /DB_XREF=gi:4504548 /UG=Hs.289114 hexabrachion (tenascin C, cytotactin) /FL=gb:M55618.1 gb:NM_002160.1 NM_002160 tenascin C TNC 3371 NM_002160 0007155 // cell adhesion // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0009611 // response to wounding // inferred from expression pattern 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay 0005102 // receptor binding // inferred from electronic annotation /// 0005488 // binding // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation 201646_at AA885297 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA885297 /FEA=EST /DB_XREF=gi:2994374 /DB_XREF=est:al58h03.s1 /CLONE=IMAGE:1461557 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1 AA885297 scavenger receptor class B, member 2 SCARB2 950 NM_005506 0007155 // cell adhesion // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201647_s_at NM_005506 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005506.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) (CD36L2), mRNA. /FEA=mRNA /GEN=CD36L2 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 2 (lysosomal integralmembrane protein II) /DB_XREF=gi:5031630 /UG=Hs.323567 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) /FL=gb:D12676.1 gb:NM_005506.1 NM_005506 scavenger receptor class B, member 2 SCARB2 950 NM_005506 0007155 // cell adhesion // inferred from electronic annotation 0005624 // membrane fraction // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201648_at AL039831 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL039831 /FEA=EST /DB_XREF=gi:5935215 /DB_XREF=est:DKFZp434D1112_s1 /CLONE=DKFZp434D1112 /UG=Hs.50651 Janus kinase 1 (a protein tyrosine kinase) /FL=gb:M64174.1 gb:NM_002227.1 AL039831 Janus kinase 1 (a protein tyrosine kinase) JAK1 3716 NM_002227 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0007167 // enzyme linked receptor protein signaling pathway // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // traceable author statement /// 0007243 // protein kinase cascade // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // traceable author statement /// 0004715 // non-membrane spanning protein tyrosine kinase activity // inferred from electronic annotation /// 0004718 // Janus kinase activity // inferred from electronic annotation /// 0005131 // growth hormone receptor binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201649_at NM_004223 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004223.1 /DEF=Homo sapiens ubiquitin-conjugating enzyme E2L 6 (UBE2L6), mRNA. /FEA=mRNA /GEN=UBE2L6 /PROD=ubiquitin-conjugating enzyme E2L 6 /DB_XREF=gi:4759281 /UG=Hs.169895 ubiquitin-conjugating enzyme E2L 6 /FL=gb:AF031141.1 gb:AF061736.1 gb:NM_004223.1 NM_004223 ubiquitin-conjugating enzyme E2L 6 UBE2L6 9246 NM_004223 /// NM_198183 0006464 // protein modification process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0019941 // modification-dependent protein catabolic process // inferred from electronic annotation /// 0032020 // ISG15-protein conjugation // inferred from electronic annotation /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay 0004842 // ubiquitin-protein ligase activity // traceable author statement /// 0004842 // ubiquitin-protein ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0042296 // ISG15 ligase activity // inferred from electronic annotation 201650_at NM_002276 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002276.1 /DEF=Homo sapiens keratin 19 (KRT19), mRNA. /FEA=mRNA /GEN=KRT19 /PROD=keratin 19 /DB_XREF=gi:4504916 /UG=Hs.182265 keratin 19 /FL=gb:BC002539.1 gb:NM_002276.1 NM_002276 junction plakoglobin /// keratin 19 JUP /// KRT19 3728 /// 3880 NM_002230 /// NM_002276 /// NM_021991 0007155 // cell adhesion // inferred from electronic annotation /// 0007155 // cell adhesion // non-traceable author statement /// 0016337 // cell-cell adhesion // inferred from electronic annotation /// 0043627 // response to estrogen stimulus // inferred from expression pattern /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045214 // sarcomere organization // inferred from direct assay 0005624 // membrane fraction // traceable author statement /// 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0005882 // intermediate filament // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0009898 // internal side of plasma membrane // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030057 // desmosome // inferred from electronic annotation /// 0042383 // sarcolemma // inferred from electronic annotation /// 0043034 // costamere // inferred from direct assay 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // traceable author statement /// 0008307 // structural constituent of muscle // inferred from direct assay 201651_s_at NM_007229 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007229.1 /DEF=Homo sapiens protein kinase C and casein kinase substrate in neurons 2 (PACSIN2), mRNA. /FEA=mRNA /GEN=PACSIN2 /PROD=protein kinase C and casein kinase substrate inneurons 2 /DB_XREF=gi:6005825 /UG=Hs.18842 protein kinase C and casein kinase substrate in neurons 2 /FL=gb:AF128536.1 gb:NM_007229.1 NM_007229 protein kinase C and casein kinase substrate in neurons 2 PACSIN2 11252 NM_007229 0006897 // endocytosis // inferred from electronic annotation /// 0030036 // actin cytoskeleton organization // traceable author statement /// 0045806 // negative regulation of endocytosis // inferred from electronic annotation 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 201652_at NM_006837 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006837.1 /DEF=Homo sapiens COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 (COPS5), mRNA. /FEA=mRNA /GEN=COPS5 /PROD=COP9 (constitutive photomorphogenic,Arabidopsis, homolog) subunit 5 /DB_XREF=gi:5803045 /UG=Hs.198767 COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5 /FL=gb:BC001187.1 gb:BC001859.1 gb:U65928.1 gb:U70734.1 gb:NM_006837.1 NM_006837 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) COPS5 10987 NM_006837 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006412 // translation // traceable author statement /// 0051726 // regulation of cell cycle // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005852 // eukaryotic translation initiation factor 3 complex // traceable author statement /// 0008180 // signalosome // inferred from electronic annotation 0003713 // transcription coactivator activity // traceable author statement /// 0003743 // translation initiation factor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201653_at NM_005776 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005776.1 /DEF=Homo sapiens cornichon-like (CNIL), mRNA. /FEA=mRNA /GEN=CNIL /PROD=cornichon-like /DB_XREF=gi:5031638 /UG=Hs.201673 cornichon-like /FL=gb:AF104398.1 gb:AF070654.1 gb:AF031379.1 gb:NM_005776.1 NM_005776 cornichon homolog (Drosophila) CNIH 10175 NM_005776 0006810 // transport // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201654_s_at AI991033 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI991033 /FEA=EST /DB_XREF=gi:5837930 /DB_XREF=est:wu36a08.x1 /CLONE=IMAGE:2522102 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2 AI991033 heparan sulfate proteoglycan 2 HSPG2 3339 NM_005529 0007155 // cell adhesion // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201655_s_at M85289 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M85289.1 /DEF=Human heparan sulfate proteoglycan (HSPG2) mRNA, complete cds. /FEA=mRNA /GEN=HSPG2 /PROD=heparan sulfate proteoglycan /DB_XREF=gi:184426 /UG=Hs.211573 heparan sulfate proteoglycan 2 (perlecan) /FL=gb:M85289.1 gb:NM_005529.2 M85289 heparan sulfate proteoglycan 2 HSPG2 3339 NM_005529 0007155 // cell adhesion // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201656_at NM_000210 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000210.1 /DEF=Homo sapiens integrin, alpha 6 (ITGA6), mRNA. /FEA=mRNA /GEN=ITGA6 /PROD=integrin alpha chain, alpha 6 /DB_XREF=gi:4557674 /UG=Hs.227730 integrin, alpha 6 /FL=gb:NM_000210.1 NM_000210 integrin, alpha 6 ITGA6 3655 NM_000210 /// NM_001079818 0007044 // cell-substrate junction assembly // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0016337 // cell-cell adhesion // inferred from electronic annotation /// 0022409 // positive regulation of cell-cell adhesion // inferred from electronic annotation /// 0033627 // cell adhesion mediated by integrin // inferred from electronic annotation /// 0042475 // odontogenesis of dentine-containing tooth // inferred from electronic annotation /// 0046847 // filopodium formation // inferred from electronic annotation /// 0050900 // leukocyte migration // inferred from electronic annotation 0005886 // plasma membrane // inferred from electronic annotation /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0008305 // integrin complex // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016323 // basolateral plasma membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0005178 // integrin binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0043236 // laminin binding // inferred from electronic annotation 201657_at BE890745 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE890745 /FEA=EST /DB_XREF=gi:10349375 /DB_XREF=est:601431177F1 /CLONE=IMAGE:3916507 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 BE890745 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201658_at AU151560 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU151560 /FEA=EST /DB_XREF=gi:11013081 /DB_XREF=est:AU151560 /CLONE=NT2RP2005555 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 AU151560 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201659_s_at NM_001177 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001177.2 /DEF=Homo sapiens ADP-ribosylation factor-like 1 (ARL1), mRNA. /FEA=mRNA /GEN=ARL1 /PROD=ADP-ribosylation factor-like 1 /DB_XREF=gi:4755126 /UG=Hs.242894 ADP-ribosylation factor-like 1 /FL=gb:NM_001177.2 gb:L28997.1 NM_001177 ADP-ribosylation factor-like 1 ARL1 400 NM_001177 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005525 // GTP binding // inferred from electronic annotation /// 0008047 // enzyme activator activity // traceable author statement /// 0046872 // metal ion binding // inferred from electronic annotation 201660_at AL525798 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL525798 /FEA=EST /DB_XREF=gi:12789291 /DB_XREF=est:AL525798 /CLONE=CS0DC013YB08 (5 prime) /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 AL525798 Acyl-CoA synthetase long-chain family member 3, mRNA (cDNA clone MGC:48741 IMAGE:5226905) ACSL3 2181 NM_004457 /// NM_203372 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004321 // fatty-acyl-CoA synthase activity // traceable author statement /// 0004467 // long-chain-fatty-acid-CoA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 201661_s_at NM_004457 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004457.2 /DEF=Homo sapiens fatty-acid-Coenzyme A ligase, long-chain 3 (FACL3), mRNA. /FEA=mRNA /GEN=FACL3 /PROD=long-chain fatty-acid-Coenzyme A ligase 3 /DB_XREF=gi:12669907 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 NM_004457 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004321 // fatty-acyl-CoA synthase activity // traceable author statement /// 0004467 // long-chain-fatty-acid-CoA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 201662_s_at D89053 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D89053.1 /DEF=Homo sapiens mRNA for Acyl-CoA synthetase 3, complete cds. /FEA=mRNA /PROD=Acyl-CoA synthetase 3 /DB_XREF=gi:4165017 /UG=Hs.268012 fatty-acid-Coenzyme A ligase, long-chain 3 /FL=gb:NM_004457.2 gb:D89053.1 gb:AF116690.1 D89053 acyl-CoA synthetase long-chain family member 3 ACSL3 2181 NM_004457 /// NM_203372 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005792 // microsome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004321 // fatty-acyl-CoA synthase activity // traceable author statement /// 0004467 // long-chain-fatty-acid-CoA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation 201663_s_at NM_005496 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005496.1 /DEF=Homo sapiens chromosome-associated polypeptide C (CAP-C), mRNA. /FEA=mRNA /GEN=CAP-C /PROD=chromosome-associated polypeptide C /DB_XREF=gi:4885112 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1 NM_005496 structural maintenance of chromosomes 4 SMC4 10051 NM_001002800 /// NM_005496 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201664_at AL136877 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AL136877.1 /DEF=Homo sapiens mRNA; cDNA DKFZp434F205 (from clone DKFZp434F205); complete cds. /FEA=mRNA /GEN=DKFZp434F205 /PROD=hypothetical protein /DB_XREF=gi:6807670 /UG=Hs.50758 SMC4 (structural maintenance of chromosomes 4, yeast)-like 1 /FL=gb:AB019987.1 gb:NM_005496.1 gb:AL136877.1 AL136877 structural maintenance of chromosomes 4 SMC4 10051 NM_001002800 /// NM_005496 0000070 // mitotic sister chromatid segregation // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000796 // condensin complex // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0005524 // ATP binding // traceable author statement /// 0046982 // protein heterodimerization activity // inferred from physical interaction 201665_x_at NM_001021 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001021.1 /DEF=Homo sapiens ribosomal protein S17 (RPS17), mRNA. /FEA=mRNA /GEN=RPS17 /PROD=ribosomal protein S17 /DB_XREF=gi:4506692 /UG=Hs.5174 ribosomal protein S17 /FL=gb:M13932.1 gb:NM_001021.1 NM_001021 ribosomal protein S17 RPS17 6218 NM_001021 0006364 // rRNA processing // inferred from mutant phenotype /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006413 // translational initiation // non-traceable author statement /// 0006414 // translational elongation // not recorded /// 0034101 // erythrocyte homeostasis // inferred from mutant phenotype /// 0042274 // ribosomal small subunit biogenesis // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // non-traceable author statement /// 0005840 // ribosome // inferred from electronic annotation /// 0022627 // cytosolic small ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // non-traceable author statement /// 0003735 // structural constituent of ribosome // inferred from electronic annotation 201666_at NM_003254 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003254.1 /DEF=Homo sapiens tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) (TIMP1), mRNA. /FEA=mRNA /GEN=TIMP1 /PROD=tissue inhibitor of metalloproteinase 1precursor /DB_XREF=gi:4507508 /UG=Hs.5831 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) /FL=gb:BC000866.1 gb:M12670.1 gb:M59906.1 gb:NM_003254.1 NM_003254 TIMP metallopeptidase inhibitor 1 TIMP1 7076 NM_003254 0001775 // cell activation // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0051045 // negative regulation of membrane protein ectodomain proteolysis // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005576 // extracellular region // non-traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005604 // basement membrane // inferred from electronic annotation 0004857 // enzyme inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008191 // metalloendopeptidase inhibitor activity // inferred from direct assay /// 0008191 // metalloendopeptidase inhibitor activity // inferred from electronic annotation 201667_at NM_000165 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000165.2 /DEF=Homo sapiens gap junction protein, alpha 1, 43kD (connexin 43) (GJA1), mRNA. /FEA=mRNA /GEN=GJA1 /PROD=connexin 43 /DB_XREF=gi:4755136 /UG=Hs.74471 gap junction protein, alpha 1, 43kD (connexin 43) /FL=gb:M65188.1 gb:NM_000165.2 NM_000165 gap junction protein, alpha 1, 43kDa GJA1 2697 NM_000165 0006810 // transport // traceable author statement /// 0006936 // muscle contraction // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0007267 // cell-cell signaling // inferred from electronic annotation /// 0007507 // heart development // traceable author statement /// 0007507 // heart development // inferred from electronic annotation /// 0016264 // gap junction assembly // traceable author statement /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from mutant phenotype 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0005921 // gap junction // inferred from electronic annotation /// 0005922 // connexon complex // traceable author statement /// 0005922 // connexon complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0030660 // Golgi-associated vesicle membrane // not recorded 0004871 // signal transducer activity // inferred from mutant phenotype /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0015075 // ion transmembrane transporter activity // traceable author statement /// 0022857 // transmembrane transporter activity // inferred from electronic annotation 201668_x_at AW163148 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW163148 /FEA=EST /DB_XREF=gi:6302181 /DB_XREF=est:au92d06.y1 /CLONE=IMAGE:2783723 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 AW163148 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201669_s_at NM_002356 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002356.4 /DEF=Homo sapiens myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) (MACS), mRNA. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich protein kinase Csubstrate /DB_XREF=gi:11125771 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 NM_002356 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201670_s_at M68956 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:M68956.1 /DEF=Human myristoylated alanine-rich C-kinase substrate mRNA, complete cds. /FEA=mRNA /GEN=MACS /PROD=myristoylated alanine-rich C-kinase substrate /DB_XREF=gi:187386 /UG=Hs.75607 myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) /FL=gb:NM_002356.4 gb:M68956.1 gb:D10522.1 M68956 myristoylated alanine-rich protein kinase C substrate MARCKS 4082 NM_002356 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005938 // cell cortex // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042585 // germinal vesicle // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation /// 0005516 // calmodulin binding // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0051015 // actin filament binding // traceable author statement 201671_x_at BC003556 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003556.1 /DEF=Homo sapiens, ubiquitin specific protease 14 (tRNA-guanine transglycosylase), clone MGC:1453, mRNA, complete cds. /FEA=mRNA /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:13097695 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1 BC003556 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0019717 // synaptosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201672_s_at NM_005151 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005151.1 /DEF=Homo sapiens ubiquitin specific protease 14 (tRNA-guanine transglycosylase) (USP14), mRNA. /FEA=mRNA /GEN=USP14 /PROD=ubiquitin specific protease 14 (tRNA-guaninetransglycosylase) /DB_XREF=gi:4827049 /UG=Hs.75981 ubiquitin specific protease 14 (tRNA-guanine transglycosylase) /FL=gb:BC003556.1 gb:NM_005151.1 gb:U30888.1 NM_005151 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) USP14 9097 NM_001037334 /// NM_005151 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007268 // synaptic transmission // inferred from electronic annotation 0005625 // soluble fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0019717 // synaptosome // inferred from electronic annotation 0004197 // cysteine-type endopeptidase activity // traceable author statement /// 0004221 // ubiquitin thiolesterase activity // inferred from electronic annotation /// 0004843 // ubiquitin-specific protease activity // traceable author statement /// 0008193 // tRNA guanylyltransferase activity // traceable author statement /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008234 // cysteine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201673_s_at NM_002103 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002103.1 /DEF=Homo sapiens glycogen synthase 1 (muscle) (GYS1), mRNA. /FEA=mRNA /GEN=GYS1 /PROD=glycogen synthase 1 (muscle) /DB_XREF=gi:4504232 /UG=Hs.772 glycogen synthase 1 (muscle) /FL=gb:U32573.1 gb:BC002617.1 gb:J04501.1 gb:NM_002103.1 NM_002103 glycogen synthase 1 (muscle) GYS1 2997 NM_002103 0005978 // glycogen biosynthetic process // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded /// 0016234 // inclusion body // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004373 // glycogen (starch) synthase activity // not recorded /// 0004373 // glycogen (starch) synthase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation 201674_s_at BC000729 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000729.1 /DEF=Homo sapiens, A kinase (PRKA) anchor protein 1, clone MGC:1807, mRNA, complete cds. /FEA=mRNA /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:12653874 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1 BC000729 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_003488 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 201675_at NM_003488 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003488.1 /DEF=Homo sapiens A kinase (PRKA) anchor protein 1 (AKAP1), mRNA. /FEA=mRNA /GEN=AKAP1 /PROD=A kinase (PRKA) anchor protein 1 /DB_XREF=gi:4502014 /UG=Hs.78921 A kinase (PRKA) anchor protein 1 /FL=gb:BC000729.1 gb:NM_003488.1 NM_003488 A kinase (PRKA) anchor protein 1 AKAP1 8165 NM_003488 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 201676_x_at NM_002786 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002786.1 /DEF=Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), mRNA. /FEA=mRNA /GEN=PSMA1 /PROD=proteasome (prosome, macropain) subunit, alphatype, 1 /DB_XREF=gi:4506178 /UG=Hs.82159 proteasome (prosome, macropain) subunit, alpha type, 1 /FL=gb:BC002577.1 gb:NM_002786.1 NM_002786 proteasome (prosome, macropain) subunit, alpha type, 1 PSMA1 5682 NM_002786 /// NM_148976 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005839 // proteasome core complex // inferred from electronic annotation /// 0005844 // polysome // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0003723 // RNA binding // traceable author statement /// 0004175 // endopeptidase activity // inferred from electronic annotation /// 0004298 // threonine-type endopeptidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201677_at AI937543 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI937543 /FEA=EST /DB_XREF=gi:5676413 /DB_XREF=est:wp78f01.x1 /CLONE=IMAGE:2467897 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1 AI937543 Clone 23837 mRNA sequence C3orf37 56941 NM_001006109 /// NM_020187 201678_s_at NM_020187 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_020187.1 /DEF=Homo sapiens DC12 protein (DC12), mRNA. /FEA=mRNA /GEN=DC12 /PROD=DC12 protein /DB_XREF=gi:9910181 /UG=Hs.110480 DC12 protein /FL=gb:AF201934.1 gb:NM_020187.1 NM_020187 chromosome 3 open reading frame 37 C3orf37 56941 NM_001006109 /// NM_020187 201679_at BE646076 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE646076 /FEA=EST /DB_XREF=gi:9970376 /DB_XREF=est:7e92g12.x1 /CLONE=IMAGE:3292678 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 BE646076 arsenate resistance protein 2 ARS2 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 0046685 // response to arsenic // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 201680_x_at NM_015908 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015908.1 /DEF=Homo sapiens arsenate resistance protein ARS2 (ARS2), mRNA. /FEA=mRNA /GEN=ARS2 /PROD=arsenate resistance protein ARS2 /DB_XREF=gi:7706237 /UG=Hs.111801 arsenate resistance protein ARS2 /FL=gb:BC000082.1 gb:AF082871.1 gb:NM_015908.1 NM_015908 arsenate resistance protein 2 ARS2 51593 NM_001128852 /// NM_001128853 /// NM_001128854 /// NM_015908 /// NM_182800 0046685 // response to arsenic // non-traceable author statement 0005515 // protein binding // inferred from physical interaction 201681_s_at AB011155 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AB011155.1 /DEF=Homo sapiens mRNA for KIAA0583 protein, partial cds. /FEA=mRNA /GEN=KIAA0583 /PROD=KIAA0583 protein /DB_XREF=gi:3043689 /UG=Hs.170290 discs, large (Drosophila) homolog 5 /FL=gb:U61843.1 gb:NM_004747.1 AB011155 discs, large homolog 5 (Drosophila) DLG5 9231 NM_004747 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // non-traceable author statement /// 0008285 // negative regulation of cell proliferation // traceable author statement /// 0016337 // cell-cell adhesion // non-traceable author statement /// 0042981 // regulation of apoptosis // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005886 // plasma membrane // non-traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005913 // cell-cell adherens junction // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation 0005515 // protein binding // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0030159 // receptor signaling complex scaffold activity // non-traceable author statement 201682_at NM_004279 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004279.1 /DEF=Homo sapiens peptidase (mitochondrial processing) beta (PMPCB), mRNA. /FEA=mRNA /GEN=PMPCB /PROD=peptidase (mitochondrial processing) beta /DB_XREF=gi:4758733 /UG=Hs.184211 peptidase (mitochondrial processing) beta /FL=gb:AF054182.1 gb:NM_004279.1 NM_004279 peptidase (mitochondrial processing) beta PMPCB 9512 NM_004279 0006508 // proteolysis // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005759 // mitochondrial matrix // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201683_x_at BE783632 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE783632 /FEA=EST /DB_XREF=gi:10204830 /DB_XREF=est:601471206F1 /CLONE=IMAGE:3874321 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BE783632 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 201684_s_at BF001668 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF001668 /FEA=EST /DB_XREF=gi:10701943 /DB_XREF=est:7g91e03.x1 /CLONE=IMAGE:3313852 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 BF001668 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 201685_s_at NM_014828 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014828.1 /DEF=Homo sapiens KIAA0737 gene product (KIAA0737), mRNA. /FEA=mRNA /GEN=KIAA0737 /PROD=KIAA0737 gene product /DB_XREF=gi:7662273 /UG=Hs.194035 KIAA0737 gene product /FL=gb:AB018280.1 gb:NM_014828.1 NM_014828 TOX high mobility group box family member 4 TOX4 9878 NM_014828 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation 201686_x_at AF229254 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF229254.1 /DEF=Homo sapiens clone FIF 504 fibroblast growth factor 2-interacting factor (API5) mRNA, complete cds. /FEA=mRNA /GEN=API5 /PROD=fibroblast growth factor 2-interacting factor /DB_XREF=gi:12656084 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1 AF229254 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_006595 /// NR_024625 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006916 // anti-apoptosis // inferred from sequence or structural similarity /// 0006916 // anti-apoptosis // non-traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from sequence or structural similarity /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 201687_s_at NM_006595 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006595.1 /DEF=Homo sapiens API5-like 1 (API5L1), mRNA. /FEA=mRNA /GEN=API5L1 /PROD=API5-like 1 /DB_XREF=gi:5729729 /UG=Hs.227913 API5-like 1 /FL=gb:AF229254.1 gb:NM_006595.1 NM_006595 apoptosis inhibitor 5 API5 8539 NM_001142930 /// NM_001142931 /// NM_006595 /// NR_024625 0006915 // apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from mutant phenotype /// 0006916 // anti-apoptosis // inferred from sequence or structural similarity /// 0006916 // anti-apoptosis // non-traceable author statement /// 0006916 // anti-apoptosis // inferred from electronic annotation /// 0006916 // anti-apoptosis // traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from sequence or structural similarity /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0017134 // fibroblast growth factor binding // inferred from physical interaction 201688_s_at BG389015 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BG389015 /FEA=EST /DB_XREF=gi:13282461 /DB_XREF=est:602414790F1 /CLONE=IMAGE:4523087 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BG389015 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_005079 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201689_s_at BE974098 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE974098 /FEA=EST /DB_XREF=gi:10587434 /DB_XREF=est:601680437F1 /CLONE=IMAGE:3950697 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 BE974098 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_005079 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201690_s_at AA524023 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA524023 /FEA=EST /DB_XREF=gi:2264951 /DB_XREF=est:ng32e06.s1 /CLONE=IMAGE:936514 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 AA524023 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_005079 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201691_s_at NM_005079 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005079.1 /DEF=Homo sapiens tumor protein D52 (TPD52), mRNA. /FEA=mRNA /GEN=TPD52 /PROD=tumor protein D52 /DB_XREF=gi:4827037 /UG=Hs.2384 tumor protein D52 /FL=gb:NM_005079.1 gb:U18914.1 NM_005079 tumor protein D52 TPD52 7163 NM_001025252 /// NM_001025253 /// NM_005079 0009653 // anatomical structure morphogenesis // traceable author statement /// 0030183 // B cell differentiation // inferred from expression pattern /// 0046903 // secretion // traceable author statement 0005737 // cytoplasm // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0005509 // calcium ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201692_at NM_005866 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005866.1 /DEF=Homo sapiens sigma receptor (SR31747 binding protein 1) (SR-BP1), mRNA. /FEA=mRNA /GEN=SR-BP1 /PROD=sigma receptor (SR31747 binding protein 1) /DB_XREF=gi:5032116 /UG=Hs.24447 sigma receptor (SR31747 binding protein 1) /FL=gb:BC004899.1 gb:U75283.1 gb:U79528.1 gb:NM_005866.1 NM_005866 sigma non-opioid intracellular receptor 1 SIGMAR1 10280 NM_005866 /// NM_147157 0006696 // ergosterol biosynthetic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005640 // nuclear outer membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005811 // lipid particle // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0012511 // monolayer-surrounded lipid storage body // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0030054 // cell junction // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation 0000247 // C-8 sterol isomerase activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0008144 // drug binding // traceable author statement 201693_s_at AV733950 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV733950 /FEA=EST /DB_XREF=gi:10851495 /DB_XREF=est:AV733950 /CLONE=cdAADG12 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1 AV733950 early growth response 1 EGR1 1958 NM_001964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201694_s_at NM_001964 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001964.1 /DEF=Homo sapiens early growth response 1 (EGR1), mRNA. /FEA=mRNA /GEN=EGR1 /PROD=early growth response 1 /DB_XREF=gi:4503492 /UG=Hs.326035 early growth response 1 /FL=gb:M62829.1 gb:NM_001964.1 NM_001964 early growth response 1 EGR1 1958 NM_001964 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0007611 // learning or memory // inferred from electronic annotation /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0045941 // positive regulation of transcription // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016563 // transcription activator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201695_s_at NM_000270 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000270.1 /DEF=Homo sapiens nucleoside phosphorylase (NP), mRNA. /FEA=mRNA /GEN=NP /PROD=purine nucleoside phosphorylase /DB_XREF=gi:4557800 /UG=Hs.75514 nucleoside phosphorylase /FL=gb:NM_000270.1 NM_000270 nucleoside phosphorylase NP 4860 NM_000270 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // inferred from electronic annotation /// 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0006148 // inosine catabolic process // inferred from direct assay /// 0006304 // DNA modification // traceable author statement /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0034418 // urate biosynthetic process // inferred from direct assay /// 0042102 // positive regulation of T cell proliferation // inferred from direct assay /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from direct assay 0005829 // cytosol // not recorded 0003824 // catalytic activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // not recorded /// 0004731 // purine-nucleoside phosphorylase activity // inferred from direct assay /// 0004731 // purine-nucleoside phosphorylase activity // inferred from electronic annotation /// 0004731 // purine-nucleoside phosphorylase activity // traceable author statement /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0016763 // transferase activity, transferring pentosyl groups // inferred from electronic annotation 201696_at NM_005626 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005626.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 4 (SFRS4), mRNA. /FEA=mRNA /GEN=SFRS4 /PROD=splicing factor, arginineserine-rich 4 /DB_XREF=gi:5032088 /UG=Hs.76122 splicing factor, arginineserine-rich 4 /FL=gb:BC002781.1 gb:L14076.1 gb:NM_005626.1 NM_005626 splicing factor, arginine/serine-rich 4 SFRS4 6429 NM_005626 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0031202 // RNA splicing factor activity, transesterification mechanism // traceable author statement 201697_s_at NM_001379 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001379.1 /DEF=Homo sapiens DNA (cytosine-5-)-methyltransferase 1 (DNMT1), mRNA. /FEA=mRNA /GEN=DNMT1 /PROD=DNA (cytosine-5-)-methyltransferase 1 /DB_XREF=gi:4503350 /UG=Hs.77462 DNA (cytosine-5-)-methyltransferase 1 /FL=gb:NM_001379.1 NM_001379 DNA (cytosine-5-)-methyltransferase 1 DNMT1 1786 NM_001130823 /// NM_001379 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006306 // DNA methylation // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // traceable author statement /// 0003886 // DNA (cytosine-5-)-methyltransferase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from electronic annotation /// 0008168 // methyltransferase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201698_s_at NM_003769 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003769.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 9 (SFRS9), mRNA. /FEA=mRNA /GEN=SFRS9 /PROD=splicing factor, arginineserine-rich 9 /DB_XREF=gi:4506902 /UG=Hs.77608 splicing factor, arginineserine-rich 9 /FL=gb:U30825.1 gb:NM_003769.1 NM_003769 splicing factor, arginine/serine-rich 9 SFRS9 8683 NM_003769 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation 201699_at NM_002806 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002806.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 6 (PSMC6), mRNA. /FEA=mRNA /GEN=PSMC6 /PROD=proteasome (prosome, macropain) 26S subunit,ATPase, 6 /DB_XREF=gi:4506214 /UG=Hs.79357 proteasome (prosome, macropain) 26S subunit, ATPase, 6 /FL=gb:BC005390.1 gb:D78275.1 gb:AF006305.1 gb:NM_002806.1 NM_002806 proteasome (prosome, macropain) 26S subunit, ATPase, 6 PSMC6 5706 NM_002806 0006511 // ubiquitin-dependent protein catabolic process // inferred by curator /// 0030163 // protein catabolic process // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016887 // ATPase activity // traceable author statement /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0030674 // protein binding, bridging // non-traceable author statement 201700_at NM_001760 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001760.1 /DEF=Homo sapiens cyclin D3 (CCND3), mRNA. /FEA=mRNA /GEN=CCND3 /PROD=cyclin D3 /DB_XREF=gi:4502618 /UG=Hs.83173 cyclin D3 /FL=gb:M90814.1 gb:M92287.1 gb:NM_001760.1 NM_001760 cyclin D3 CCND3 896 NM_001136017 /// NM_001136125 /// NM_001136126 /// NM_001760 0001934 // positive regulation of protein amino acid phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0045737 // positive regulation of cyclin-dependent protein kinase activity // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation 0000307 // cyclin-dependent protein kinase holoenzyme complex // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction 201701_s_at NM_006320 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006320.1 /DEF=Homo sapiens progesterone membrane binding protein (PMBP), mRNA. /FEA=mRNA /GEN=PMBP /PROD=progesterone membrane binding protein /DB_XREF=gi:5453915 /UG=Hs.9071 progesterone membrane binding protein /FL=gb:NM_006320.1 NM_006320 progesterone receptor membrane component 2 PGRMC2 10424 NM_006320 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0003707 // steroid hormone receptor activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // traceable author statement /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0020037 // heme binding // inferred from electronic annotation /// 0046914 // transition metal ion binding // inferred from electronic annotation 201702_s_at AI492873 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI492873 /FEA=EST /DB_XREF=gi:4393876 /DB_XREF=est:th78b05.x1 /CLONE=IMAGE:2124753 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1 AI492873 protein phosphatase 1, regulatory (inhibitor) subunit 10 PPP1R10 5514 NM_002714 0006350 // transcription // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201703_s_at NM_002714 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002714.1 /DEF=Homo sapiens protein phosphatase 1, regulatory subunit 10 (PPP1R10), mRNA. /FEA=mRNA /GEN=PPP1R10 /PROD=protein phosphatase 1, regulatory subunit 10 /DB_XREF=gi:4506008 /UG=Hs.106019 protein phosphatase 1, regulatory subunit 10 /FL=gb:NM_002714.1 NM_002714 protein phosphatase 1, regulatory (inhibitor) subunit 10 PPP1R10 5514 NM_002714 0006350 // transcription // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004864 // protein phosphatase inhibitor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0030528 // transcription regulator activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201704_at NM_001247 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001247.1 /DEF=Homo sapiens ectonucleoside triphosphate diphosphohydrolase 6 (putative function) (ENTPD6), mRNA. /FEA=mRNA /GEN=ENTPD6 /PROD=ectonucleoside triphosphate diphosphohydrolase 6(putative function) /DB_XREF=gi:4557422 /UG=Hs.12330 ectonucleoside triphosphate diphosphohydrolase 6 (putative function) /FL=gb:AF039916.1 gb:NM_001247.1 NM_001247 ectonucleoside triphosphate diphosphohydrolase 6 (putative function) ENTPD6 955 NM_001114089 /// NM_001247 0000139 // Golgi membrane // inferred from electronic annotation /// 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0000287 // magnesium ion binding // inferred from electronic annotation /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017110 // nucleoside-diphosphatase activity // inferred from electronic annotation 201705_at NM_002811 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002811.1 /DEF=Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) (PSMD7), mRNA. /FEA=mRNA /GEN=PSMD7 /PROD=proteasome (prosome, macropain) 26S subunit,non-ATPase, 7 (Mov34 homolog) /DB_XREF=gi:4506230 /UG=Hs.155543 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog) /FL=gb:NM_002811.1 gb:D50063.1 NM_002811 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 PSMD7 5713 NM_002811 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0005838 // proteasome regulatory particle // traceable author statement /// 0043234 // protein complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201706_s_at BC000496 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000496.1 /DEF=Homo sapiens, peroxisomal farnesylated protein, clone MGC:8403, mRNA, complete cds. /FEA=mRNA /PROD=peroxisomal farnesylated protein /DB_XREF=gi:12653448 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1 BC000496 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_002857 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0007031 // peroxisome organization // non-traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201707_at NM_002857 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002857.1 /DEF=Homo sapiens peroxisomal farnesylated protein (PXF), mRNA. /FEA=mRNA /GEN=PXF /PROD=peroxisomal farnesylated protein /DB_XREF=gi:4506338 /UG=Hs.168670 peroxisomal farnesylated protein /FL=gb:BC000496.1 gb:NM_002857.1 gb:AB018541.1 NM_002857 peroxisomal biogenesis factor 19 PEX19 5824 NM_001131039 /// NM_002857 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0007031 // peroxisome organization // inferred from electronic annotation /// 0007031 // peroxisome organization // non-traceable author statement 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005777 // peroxisome // inferred from electronic annotation /// 0005777 // peroxisome // inferred from sequence or structural similarity /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201708_s_at AW083371 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW083371 /FEA=EST /DB_XREF=gi:6038609 /DB_XREF=est:xc09g02.x1 /CLONE=IMAGE:2583794 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1 AW083371 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_003634 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation 201709_s_at NM_003634 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003634.1 /DEF=Homo sapiens NIPSNAP, C. elegans, homolog 1 (NIPSNAP1), mRNA. /FEA=mRNA /GEN=NIPSNAP1 /PROD=NIPSNAP, C. elegans, homolog 1 /DB_XREF=gi:4505398 /UG=Hs.173878 NIPSNAP, C. elegans, homolog 1 /FL=gb:BC002371.1 gb:NM_003634.1 NM_003634 nipsnap homolog 1 (C. elegans) NIPSNAP1 8508 NM_003634 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation 201710_at NM_002466 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002466.1 /DEF=Homo sapiens v-myb avian myeloblastosis viral oncogene homolog-like 2 (MYBL2), mRNA. /FEA=mRNA /GEN=MYBL2 /PROD=v-myb avian myeloblastosis viral oncogenehomolog-like 2 /DB_XREF=gi:4505292 /UG=Hs.179718 v-myb avian myeloblastosis viral oncogene homolog-like 2 /FL=gb:NM_002466.1 NM_002466 v-myb myeloblastosis viral oncogene homolog (avian)-like 2 MYBL2 4605 NM_002466 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement 201711_x_at AI681120 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI681120 /FEA=EST /DB_XREF=gi:4891302 /DB_XREF=est:tx44b06.x1 /CLONE=IMAGE:2272403 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 AI681120 RAN binding protein 2 RANBP2 5903 NM_006267 0006457 // protein folding // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201712_s_at NM_006267 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006267.2 /DEF=Homo sapiens RAN binding protein 2 (RANBP2), mRNA. /FEA=mRNA /GEN=RANBP2 /PROD=RAN binding protein 2 /DB_XREF=gi:6382078 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 NM_006267 RAN binding protein 2 RANBP2 5903 NM_006267 0006457 // protein folding // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201713_s_at D42063 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:D42063.1 /DEF=Human mRNA for RanBP2 (Ran-binding protein 2), complete cds. /FEA=mRNA /PROD=RanBP2 (Ran-binding protein 2) /DB_XREF=gi:924266 /UG=Hs.199179 RAN binding protein 2 /FL=gb:NM_006267.2 gb:D42063.1 D42063 RAN binding protein 2 RANBP2 5903 NM_006267 0006457 // protein folding // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003755 // peptidyl-prolyl cis-trans isomerase activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008536 // Ran GTPase binding // traceable author statement /// 0016853 // isomerase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201714_at NM_001070 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001070.1 /DEF=Homo sapiens tubulin, gamma 1 (TUBG1), mRNA. /FEA=mRNA /GEN=TUBG1 /PROD=tubulin, gamma 1 /DB_XREF=gi:4507730 /UG=Hs.21635 tubulin, gamma 1 /FL=gb:BC000619.1 gb:M61764.1 gb:NM_001070.1 NM_001070 tubulin, gamma 1 TUBG1 7283 NM_001070 0000212 // meiotic spindle organization // inferred from sequence or structural similarity /// 0000212 // meiotic spindle organization // inferred from electronic annotation /// 0000226 // microtubule cytoskeleton organization // traceable author statement /// 0007017 // microtubule-based process // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation 0000242 // pericentriolar material // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0000930 // gamma-tubulin complex // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005813 // centrosome // inferred from direct assay /// 0005813 // centrosome // inferred from electronic annotation /// 0005813 // centrosome // traceable author statement /// 0005816 // spindle pole body // traceable author statement /// 0005827 // polar microtubule // inferred from direct assay /// 0005827 // polar microtubule // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0005874 // microtubule // traceable author statement /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0005881 // cytoplasmic microtubule // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003924 // GTPase activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005525 // GTP binding // inferred from electronic annotation 201715_s_at NM_014977 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014977.1 /DEF=Homo sapiens KIAA0670 proteinacinus (KIAA0670), mRNA. /FEA=mRNA /GEN=KIAA0670 /PROD=KIAA0670 proteinacinus /DB_XREF=gi:7662237 /UG=Hs.227133 KIAA0670 proteinacinus /FL=gb:AF124726.1 gb:NM_014977.1 NM_014977 apoptotic chromatin condensation inducer 1 ACIN1 22985 NM_014977 0006915 // apoptosis // inferred from electronic annotation /// 0030218 // erythrocyte differentiation // inferred from expression pattern /// 0030263 // apoptotic chromosome condensation // inferred from direct assay /// 0045657 // positive regulation of monocyte differentiation // inferred from expression pattern 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // non-traceable author statement /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0016887 // ATPase activity // non-traceable author statement /// 0019899 // enzyme binding // non-traceable author statement 201716_at NM_003099 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003099.1 /DEF=Homo sapiens sorting nexin 1 (SNX1), mRNA. /FEA=mRNA /GEN=SNX1 /PROD=sorting nexin 1 /DB_XREF=gi:4507138 /UG=Hs.75283 sorting nexin 1 /FL=gb:BC000357.1 gb:U53225.1 gb:AF065483.1 gb:NM_003099.1 NM_003099 sorting nexin 1 SNX1 6642 NM_003099 /// NM_148955 /// NM_152826 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006897 // endocytosis // traceable author statement /// 0007154 // cell communication // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation /// 0035091 // phosphoinositide binding // inferred from electronic annotation 201717_at NM_004927 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004927.1 /DEF=Homo sapiens chromosome 11 open reading frame 4 (C11ORF4), mRNA. /FEA=mRNA /GEN=C11ORF4 /PROD=chromosome 11 open reading frame 4 /DB_XREF=gi:4826648 /UG=Hs.75859 chromosome 11 open reading frame 4 /FL=gb:U39400.1 gb:BC004378.1 gb:NM_004927.1 NM_004927 mitochondrial ribosomal protein L49 MRPL49 740 NM_004927 0006412 // translation // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from electronic annotation 201718_s_at BF511685 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF511685 /FEA=EST /DB_XREF=gi:11594983 /DB_XREF=est:UI-H-BI4-aom-c-09-0-UI.s1 /CLONE=IMAGE:3085432 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1 BF511685 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001431 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008091 // spectrin // traceable author statement /// 0019898 // extrinsic to membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201719_s_at NM_001431 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001431.1 /DEF=Homo sapiens erythrocyte membrane protein band 4.1-like 2 (EPB41L2), mRNA. /FEA=mRNA /GEN=EPB41L2 /PROD=erythrocyte membrane protein band 4.1-like 2 /DB_XREF=gi:4503578 /UG=Hs.7857 erythrocyte membrane protein band 4.1-like 2 /FL=gb:AF027299.1 gb:NM_001431.1 NM_001431 erythrocyte membrane protein band 4.1-like 2 EPB41L2 2037 NM_001135554 /// NM_001135555 /// NM_001431 0030866 // cortical actin cytoskeleton organization // inferred from electronic annotation 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0008091 // spectrin // traceable author statement /// 0019898 // extrinsic to membrane // inferred from electronic annotation /// 0031012 // extracellular matrix // inferred from direct assay 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008092 // cytoskeletal protein binding // inferred from electronic annotation 201720_s_at AI589086 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI589086 /FEA=EST /DB_XREF=gi:4598134 /DB_XREF=est:tf80g10.x1 /CLONE=IMAGE:2105634 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1 AI589086 lysosomal multispanning membrane protein 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201721_s_at NM_006762 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006762.1 /DEF=Homo sapiens Lysosomal-associated multispanning membrane protein-5 (LAPTM5), mRNA. /FEA=mRNA /GEN=LAPTM5 /PROD=Lysosomal-associated multispanning membraneprotein-5 /DB_XREF=gi:5803055 /UG=Hs.79356 Lysosomal-associated multispanning membrane protein-5 /FL=gb:U51240.1 gb:NM_006762.1 gb:U30498.1 NM_006762 lysosomal multispanning membrane protein 5 LAPTM5 7805 NM_006762 0006810 // transport // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0005764 // lysosome // traceable author statement /// 0005765 // lysosomal membrane // inferred from electronic annotation /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201722_s_at AV692127 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AV692127 /FEA=EST /DB_XREF=gi:10293990 /DB_XREF=est:AV692127 /CLONE=GKCAOB04 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 AV692127 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) GALNT1 2589 NM_020474 0006493 // protein amino acid O-linked glycosylation // inferred from electronic annotation /// 0006493 // protein amino acid O-linked glycosylation // traceable author statement /// 0018242 // protein amino acid O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein amino acid O-linked glycosylation via threonine // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // traceable author statement /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005529 // sugar binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay 201723_s_at U41514 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U41514.1 /DEF=Human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase mRNA, complete cds. /FEA=mRNA /PROD=UDP-GalNAc:polypeptideN-acetylgalactosaminyltransferase /DB_XREF=gi:1136284 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 U41514 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) GALNT1 2589 NM_020474 0006493 // protein amino acid O-linked glycosylation // inferred from electronic annotation /// 0006493 // protein amino acid O-linked glycosylation // traceable author statement /// 0018242 // protein amino acid O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein amino acid O-linked glycosylation via threonine // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // traceable author statement /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005529 // sugar binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay 201724_s_at NM_020474 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_020474.2 /DEF=Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1), mRNA. /FEA=mRNA /GEN=GALNT1 /PROD=polypeptide N-acetylgalactosaminyltransferase 1 /DB_XREF=gi:13124890 /UG=Hs.80120 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) /FL=gb:U41514.1 gb:NM_020474.2 NM_020474 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) GALNT1 2589 NM_020474 0006493 // protein amino acid O-linked glycosylation // inferred from electronic annotation /// 0006493 // protein amino acid O-linked glycosylation // traceable author statement /// 0018242 // protein amino acid O-linked glycosylation via serine // inferred from direct assay /// 0018243 // protein amino acid O-linked glycosylation via threonine // inferred from direct assay 0005576 // extracellular region // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // traceable author statement /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from electronic annotation /// 0004653 // polypeptide N-acetylgalactosaminyltransferase activity // inferred from direct assay /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005529 // sugar binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016757 // transferase activity, transferring glycosyl groups // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from electronic annotation /// 0030145 // manganese ion binding // inferred from direct assay 201725_at NM_006023 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006023.1 /DEF=Homo sapiens D123 gene product (D123), mRNA. /FEA=mRNA /GEN=D123 /PROD=D123 gene product /DB_XREF=gi:5174422 /UG=Hs.82043 D123 gene product /FL=gb:BC001600.1 gb:D14878.1 gb:U27112.1 gb:NM_006023.1 NM_006023 cell division cycle 123 homolog (S. cerevisiae) CDC123 8872 NM_006023 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0051301 // cell division // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 201726_at BC003376 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC003376.1 /DEF=Homo sapiens, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), clone MGC:5084, mRNA, complete cds. /FEA=mRNA /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:13097227 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1 BC003376 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) ELAVL1 1994 NM_001419 0007275 // multicellular organismal development // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 201727_s_at NM_001419 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001419.1 /DEF=Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mRNA. /FEA=mRNA /GEN=ELAVL1 /PROD=ELAV (embryonic lethal, abnormal vision,Drosophila)-like 1 (Hu antigen R) /DB_XREF=gi:4503550 /UG=Hs.12379 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) /FL=gb:U38175.1 gb:BC003376.1 gb:NM_001419.1 NM_001419 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) ELAVL1 1994 NM_001419 0007275 // multicellular organismal development // traceable author statement /// 0048255 // mRNA stabilization // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003729 // mRNA binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction 201728_s_at AA904674 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA904674 /FEA=EST /DB_XREF=gi:3039797 /DB_XREF=est:oj73f02.s1 /CLONE=IMAGE:1503963 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1 AA904674 KIAA0100 KIAA0100 9703 NM_014680 0006099 // tricarboxylic acid cycle // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0008924 // malate dehydrogenase (acceptor) activity // inferred from electronic annotation 201729_s_at NM_014680 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014680.1 /DEF=Homo sapiens KIAA0100 gene product (KIAA0100), mRNA. /FEA=mRNA /GEN=KIAA0100 /PROD=KIAA0100 gene product /DB_XREF=gi:7661903 /UG=Hs.151761 KIAA0100 gene product /FL=gb:D43947.1 gb:NM_014680.1 NM_014680 KIAA0100 KIAA0100 9703 NM_014680 0006099 // tricarboxylic acid cycle // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation 0008924 // malate dehydrogenase (acceptor) activity // inferred from electronic annotation 201730_s_at BF110993 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF110993 /FEA=EST /DB_XREF=gi:10940683 /DB_XREF=est:7n42e09.x1 /CLONE=IMAGE:3567448 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1 BF110993 translocated promoter region (to activated MET oncogene) TPR 7175 NM_003292 0006412 // translation // inferred from electronic annotation /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 201731_s_at NM_003292 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003292.1 /DEF=Homo sapiens translocated promoter region (to activated MET oncogene) (TPR), mRNA. /FEA=mRNA /GEN=TPR /PROD=translocated promoter region (to activated METoncogene) /DB_XREF=gi:4507658 /UG=Hs.169750 translocated promoter region (to activated MET oncogene) /FL=gb:NM_003292.1 NM_003292 translocated promoter region (to activated MET oncogene) TPR 7175 NM_003292 0006412 // translation // inferred from electronic annotation /// 0006434 // seryl-tRNA aminoacylation // inferred from electronic annotation /// 0006606 // protein import into nucleus // traceable author statement /// 0006606 // protein import into nucleus // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0051028 // mRNA transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // inferred from electronic annotation /// 0005643 // nuclear pore // traceable author statement /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004828 // serine-tRNA ligase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation 201732_s_at AF029346 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF029346.1 /DEF=Homo sapiens chloride channel protein 3 (CLCN3) mRNA, complete cds. /FEA=CDS /GEN=CLCN3 /PROD=chloride channel protein 3 /DB_XREF=gi:2599547 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AF029346 chloride channel 3 CLCN3 1182 NM_001829 /// NM_173872 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201733_at AA902971 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA902971 /FEA=EST /DB_XREF=gi:3038094 /DB_XREF=est:ok44c09.s1 /CLONE=IMAGE:1516816 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AA902971 chloride channel 3 CLCN3 1182 NM_001829 /// NM_173872 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201734_at AI760629 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI760629 /FEA=EST /DB_XREF=gi:5176296 /DB_XREF=est:wi66e06.x1 /CLONE=IMAGE:2398306 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 AI760629 Chloride channel protein 3 (CLCN3) CLCN3 1182 NM_001829 /// NM_173872 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201735_s_at NM_001829 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001829.1 /DEF=Homo sapiens chloride channel 3 (CLCN3), mRNA. /FEA=mRNA /GEN=CLCN3 /PROD=chloride channel 3 /DB_XREF=gi:4502868 /UG=Hs.174139 chloride channel 3 /FL=gb:AF029346.1 gb:NM_001829.1 gb:AF172729.1 NM_001829 chloride channel 3 CLCN3 1182 NM_001829 /// NM_173872 0006810 // transport // inferred from electronic annotation /// 0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006821 // chloride transport // inferred from electronic annotation /// 0006885 // regulation of pH // traceable author statement /// 0048388 // endosomal lumen acidification // traceable author statement 0000139 // Golgi membrane // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0005769 // early endosome // inferred from sequence or structural similarity /// 0005770 // late endosome // inferred from direct assay /// 0005770 // late endosome // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // non-traceable author statement /// 0012506 // vesicle membrane // inferred from direct assay /// 0012506 // vesicle membrane // inferred from sequence or structural similarity /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation 0005216 // ion channel activity // inferred from electronic annotation /// 0005244 // voltage-gated ion channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // inferred from electronic annotation /// 0005247 // voltage-gated chloride channel activity // traceable author statement /// 0005254 // chloride channel activity // inferred from electronic annotation /// 0005254 // chloride channel activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0030165 // PDZ domain binding // inferred from direct assay /// 0030165 // PDZ domain binding // inferred from sequence or structural similarity /// 0031404 // chloride ion binding // inferred from electronic annotation /// 0042803 // protein homodimerization activity // non-traceable author statement /// 0046982 // protein heterodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from sequence or structural similarity 201736_s_at BF000409 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF000409 /FEA=EST /DB_XREF=gi:10700684 /DB_XREF=est:7h27h07.x1 /CLONE=IMAGE:3317245 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1 BF000409 membrane-associated ring finger (C3HC4) 6 MARCH6 10299 NM_005885 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201737_s_at NM_005885 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005885.1 /DEF=Homo sapiens similar to S. cerevisiae SSM4 (TEB4), mRNA. /FEA=mRNA /GEN=TEB4 /PROD=similar to S. cerevisiae SSM4 /DB_XREF=gi:5032166 /UG=Hs.20141 similar to S. cerevisiae SSM4 /FL=gb:AF009301.1 gb:NM_005885.1 NM_005885 membrane-associated ring finger (C3HC4) 6 MARCH6 10299 NM_005885 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201738_at NM_005875 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005875.1 /DEF=Homo sapiens translation factor sui1 homolog (GC20), mRNA. /FEA=mRNA /GEN=GC20 /PROD=translation factor sui1 homolog /DB_XREF=gi:5031710 /UG=Hs.21756 translation factor sui1 homolog /FL=gb:AF064607.1 gb:AF077052.1 gb:NM_005875.1 gb:AF263452.1 NM_005875 eukaryotic translation initiation factor 1B EIF1B 10289 NM_005875 0006412 // translation // inferred from electronic annotation /// 0006413 // translational initiation // inferred from electronic annotation /// 0006446 // regulation of translational initiation // non-traceable author statement 0003743 // translation initiation factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201739_at NM_005627 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005627.1 /DEF=Homo sapiens serumglucocorticoid regulated kinase (SGK), mRNA. /FEA=mRNA /GEN=SGK /PROD=serumglucocorticoid regulated kinase /DB_XREF=gi:5032090 /UG=Hs.296323 serumglucocorticoid regulated kinase /FL=gb:BC001263.1 gb:NM_005627.1 gb:AF153609.1 NM_005627 serum/glucocorticoid regulated kinase 1 SGK1 6446 NM_001143676 /// NM_001143677 /// NM_001143678 /// NM_005627 0006468 // protein amino acid phosphorylation // inferred from electronic annotation /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006814 // sodium ion transport // traceable author statement /// 0006883 // cellular sodium ion homeostasis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0006950 // response to stress // traceable author statement /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004672 // protein kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // inferred from electronic annotation /// 0004674 // protein serine/threonine kinase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation 201740_at NM_004551 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004551.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) (NDUFS3), mRNA. /FEA=mRNA /GEN=NDUFS3 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 3(30kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758787 /UG=Hs.5273 NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) /FL=gb:BC000617.1 gb:AF067139.1 gb:NM_004551.1 gb:AF100743.1 NM_004551 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) NDUFS3 4722 NM_004551 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006800 // oxygen and reactive oxygen species metabolic process // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006917 // induction of apoptosis // inferred from mutant phenotype /// 0022900 // electron transport chain // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // non-traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // inferred from direct assay /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from direct assay 0003954 // NADH dehydrogenase activity // inferred from mutant phenotype /// 0003954 // NADH dehydrogenase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement /// 0008137 // NADH dehydrogenase (ubiquinone) activity // inferred from electronic annotation /// 0009055 // electron carrier activity // non-traceable author statement /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016651 // oxidoreductase activity, acting on NADH or NADPH // inferred from electronic annotation 201741_x_at M69040 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:M69040.1 /DEF=Human SF2p33 mRNA, complete cds. /FEA=mRNA /PROD=SF2p33 /DB_XREF=gi:338046 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1 M69040 splicing factor, arginine/serine-rich 1 SFRS1 6426 NM_001078166 /// NM_006924 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201742_x_at NM_006924 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006924.1 /DEF=Homo sapiens splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) (SFRS1), mRNA. /FEA=mRNA /GEN=SFRS1 /PROD=splicing factor, arginineserine-rich 1(splicing factor 2, alternate splicing factor) /DB_XREF=gi:5902075 /UG=Hs.73737 splicing factor, arginineserine-rich 1 (splicing factor 2, alternate splicing factor) /FL=gb:M69040.1 gb:NM_006924.1 NM_006924 splicing factor, arginine/serine-rich 1 SFRS1 6426 NM_001078166 /// NM_006924 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006376 // mRNA splice site selection // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0060048 // cardiac muscle contraction // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201743_at NM_000591 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000591.1 /DEF=Homo sapiens CD14 antigen (CD14), mRNA. /FEA=mRNA /GEN=CD14 /PROD=CD14 antigen precursor /DB_XREF=gi:4557416 /UG=Hs.75627 CD14 antigen /FL=gb:M86511.1 gb:AF097942.1 gb:NM_000591.1 NM_000591 CD14 molecule CD14 929 NM_000591 /// NM_001040021 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0006909 // phagocytosis // traceable author statement /// 0006915 // apoptosis // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // inferred from electronic annotation /// 0007166 // cell surface receptor linked signal transduction // traceable author statement 0005576 // extracellular region // not recorded /// 0005886 // plasma membrane // not recorded /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored to membrane // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046696 // lipopolysaccharide receptor complex // inferred from electronic annotation 0001847 // opsonin receptor activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0016019 // peptidoglycan receptor activity // traceable author statement 201744_s_at NM_002345 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002345.1 /DEF=Homo sapiens lumican (LUM), mRNA. /FEA=mRNA /GEN=LUM /PROD=lumican /DB_XREF=gi:4505046 /UG=Hs.79914 lumican /FL=gb:NM_002345.1 gb:U18728.1 gb:U21128.1 NM_002345 lumican LUM 4060 NM_002345 0007601 // visual perception // traceable author statement /// 0030199 // collagen fibril organization // non-traceable author statement 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005583 // fibrillar collagen // inferred from direct assay 0005201 // extracellular matrix structural constituent // non-traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005518 // collagen binding // inferred from direct assay 201745_at NM_002822 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002822.1 /DEF=Homo sapiens protein tyrosine kinase 9 (PTK9), mRNA. /FEA=mRNA /GEN=PTK9 /PROD=protein tyrosine kinase 9 /DB_XREF=gi:4506274 /UG=Hs.82643 protein tyrosine kinase 9 /FL=gb:NM_002822.1 gb:U02680.1 NM_002822 twinfilin, actin-binding protein, homolog 1 (Drosophila) TWF1 5756 NM_002822 0006468 // protein amino acid phosphorylation // inferred from direct assay 0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity 0003779 // actin binding // inferred from electronic annotation /// 0004713 // protein tyrosine kinase activity // inferred from direct assay 201746_at NM_000546 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000546.2 /DEF=Homo sapiens tumor protein p53 (Li-Fraumeni syndrome) (TP53), mRNA. /FEA=mRNA /GEN=TP53 /PROD=tumor protein p53 /DB_XREF=gi:8400737 /UG=Hs.1846 tumor protein p53 (Li-Fraumeni syndrome) /FL=gb:AF307851.1 gb:BC003596.1 gb:M14694.1 gb:M14695.1 gb:NM_000546.2 NM_000546 tumor protein p53 TP53 7157 NM_000546 /// NM_001126112 /// NM_001126113 /// NM_001126114 /// NM_001126115 /// NM_001126116 /// NM_001126117 0000060 // protein import into nucleus, translocation // inferred from electronic annotation /// 0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001836 // release of cytochrome c from mitochondria // inferred from electronic annotation /// 0002326 // B cell lineage commitment // inferred from electronic annotation /// 0002347 // response to tumor cell // inferred from electronic annotation /// 0002360 // T cell lineage commitment // inferred from electronic annotation /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from direct assay /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006461 // protein complex assembly // inferred from direct assay /// 0006915 // apoptosis // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0006917 // induction of apoptosis // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from electronic annotation /// 0006974 // response to DNA damage stimulus // inferred from expression pattern /// 0006974 // response to DNA damage stimulus // inferred from direct assay /// 0006983 // ER overload response // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0007050 // cell cycle arrest // traceable author statement /// 0007275 // multicellular organismal development // inferred from mutant phenotype /// 0007406 // negative regulation of neuroblast proliferation // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0007569 // cell aging // inferred from mutant phenotype /// 0008104 // protein localization // inferred from direct assay /// 0008156 // negative regulation of DNA replication // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008629 // induction of apoptosis by intracellular signals // traceable author statement /// 0008635 // caspase activation via cytochrome c // inferred from direct assay /// 0009411 // response to UV // inferred from electronic annotation /// 0009792 // embryonic development ending in birth or egg hatching // inferred from electronic annotation /// 0010165 // response to X-ray // inferred from electronic annotation /// 0010332 // response to gamma radiation // inferred from electronic annotation /// 0010552 // positive regulation of specific transcription from RNA polymerase II promoter // inferred from direct assay /// 0018144 // RNA-protein covalent cross-linking // inferred from electronic annotation /// 0030154 // cell differentiation // traceable author statement /// 0030308 // negative regulation of cell growth // inferred from mutant phenotype /// 0030308 // negative regulation of cell growth // inferred from electronic annotation /// 0030330 // DNA damage response, signal transduction by p53 class mediator // traceable author statement /// 0031571 // G1 DNA damage checkpoint // inferred from electronic annotation /// 0042149 // cellular response to glucose starvation // inferred from direct assay /// 0042493 // response to drug // inferred from electronic annotation /// 0042771 // DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis // inferred from direct assay /// 0042771 // DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis // inferred from electronic annotation /// 0042981 // regulation of apoptosis // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from electronic annotation /// 0043066 // negative regulation of apoptosis // inferred from electronic annotation /// 0043525 // positive regulation of neuron apoptosis // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0045786 // negative regulation of cell cycle // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // traceable author statement /// 0048147 // negative regulation of fibroblast proliferation // inferred from electronic annotation /// 0051097 // negative regulation of helicase activity // traceable author statement /// 0051262 // protein tetramerization // traceable author statement /// 0051453 // regulation of intracellular pH // inferred from electronic annotation 0005626 // insoluble fraction // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from direct assay /// 0005657 // replication fork // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016363 // nuclear matrix // inferred from direct assay /// 0016605 // PML body // inferred from direct assay 0000739 // DNA strand annealing activity // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from mutant phenotype /// 0003677 // DNA binding // traceable author statement /// 0003682 // chromatin binding // inferred from direct assay /// 0003700 // transcription factor activity // inferred from direct assay /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0004518 // nuclease activity // traceable author statement /// 0005507 // copper ion binding // inferred from direct assay /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from direct assay /// 0008270 // zinc ion binding // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051087 // chaperone binding // inferred from physical interaction 201747_s_at AI769566 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI769566 /FEA=EST /DB_XREF=gi:5236075 /DB_XREF=est:wj24e11.x1 /CLONE=IMAGE:2403788 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1 AI769566 scaffold attachment factor B SAFB 6294 NM_002967 0006325 // establishment or maintenance of chromatin architecture // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201748_s_at NM_002967 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002967.1 /DEF=Homo sapiens scaffold attachment factor B (SAFB), mRNA. /FEA=mRNA /GEN=SAFB /PROD=scaffold attachment factor B /DB_XREF=gi:4506778 /UG=Hs.23978 scaffold attachment factor B /FL=gb:U72355.1 gb:NM_002967.1 NM_002967 scaffold attachment factor B SAFB 6294 NM_002967 0006325 // establishment or maintenance of chromatin architecture // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003690 // double-stranded DNA binding // traceable author statement /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201749_at BF969352 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF969352 /FEA=EST /DB_XREF=gi:12336567 /DB_XREF=est:602271616F1 /CLONE=IMAGE:4359794 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1 BF969352 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 0001666 // response to hypoxia // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0051605 // protein maturation via proteolysis // inferred from direct assay /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005624 // membrane fraction // inferred from direct assay /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0031302 // intrinsic to endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201750_s_at NM_001397 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001397.1 /DEF=Homo sapiens endothelin converting enzyme 1 (ECE1), mRNA. /FEA=mRNA /GEN=ECE1 /PROD=endothelin converting enzyme 1 /DB_XREF=gi:4503442 /UG=Hs.288203 endothelin converting enzyme 1 /FL=gb:NM_001397.1 gb:AB031742.1 gb:D49471.1 NM_001397 endothelin converting enzyme 1 ECE1 1889 NM_001113347 /// NM_001113348 /// NM_001113349 /// NM_001397 0001666 // response to hypoxia // inferred from electronic annotation /// 0001921 // positive regulation of receptor recycling // inferred from mutant phenotype /// 0003100 // regulation of systemic arterial blood pressure by endothelin // inferred by curator /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007507 // heart development // inferred from mutant phenotype /// 0016485 // protein processing // inferred from electronic annotation /// 0016486 // peptide hormone processing // inferred from direct assay /// 0019229 // regulation of vasoconstriction // inferred by curator /// 0034959 // endothelin maturation // inferred from direct assay /// 0042447 // hormone catabolic process // inferred from direct assay /// 0042733 // embryonic digit morphogenesis // inferred from mutant phenotype /// 0043583 // ear development // inferred from mutant phenotype /// 0045745 // positive regulation of G-protein coupled receptor protein signaling pathway // inferred from electronic annotation /// 0051605 // protein maturation via proteolysis // inferred from direct assay /// 0060037 // pharyngeal system development // inferred from electronic annotation 0005624 // membrane fraction // inferred from direct assay /// 0005624 // membrane fraction // inferred from electronic annotation /// 0005768 // endosome // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0031302 // intrinsic to endosome membrane // traceable author statement /// 0031982 // vesicle // inferred from sequence or structural similarity /// 0033093 // Weibel-Palade body // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay 0004175 // endopeptidase activity // inferred from direct assay /// 0004222 // metalloendopeptidase activity // inferred from electronic annotation /// 0004222 // metalloendopeptidase activity // inferred from sequence or structural similarity /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008237 // metallopeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0017046 // peptide hormone binding // inferred by curator /// 0042803 // protein homodimerization activity // inferred from physical interaction /// 0046872 // metal ion binding // inferred from electronic annotation 201751_at NM_014876 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014876.1 /DEF=Homo sapiens KIAA0063 gene product (KIAA0063), mRNA. /FEA=mRNA /GEN=KIAA0063 /PROD=KIAA0063 gene product /DB_XREF=gi:7661887 /UG=Hs.3094 KIAA0063 gene product /FL=gb:D31884.1 gb:NM_014876.1 NM_014876 Josephin domain containing 1 JOSD1 9929 NM_014876 0005634 // nucleus // inferred from direct assay 201752_s_at AI763123 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI763123 /FEA=EST /DB_XREF=gi:5178790 /DB_XREF=est:wi06f09.x1 /CLONE=IMAGE:2389481 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1 AI763123 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201753_s_at NM_019903 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_019903.1 /DEF=Homo sapiens adducin 3 (gamma) (ADD3), transcript variant 2, mRNA. /FEA=mRNA /GEN=ADD3 /PROD=adducin 3, isoform b /DB_XREF=gi:9951926 /UG=Hs.324470 adducin 3 (gamma) /FL=gb:D67031.1 gb:NM_019903.1 NM_019903 adducin 3 (gamma) ADD3 120 NM_001121 /// NM_016824 /// NM_019903 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016020 // membrane // traceable author statement 0003779 // actin binding // inferred from electronic annotation /// 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005516 // calmodulin binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201754_at NM_004374 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004374.1 /DEF=Homo sapiens cytochrome c oxidase subunit VIc (COX6C), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=COX6C /PROD=cytochrome c oxidase subunit VIc /DB_XREF=gi:4758039 /UG=Hs.74649 cytochrome c oxidase subunit VIc /FL=gb:BC000187.1 gb:NM_004374.1 NM_004374 cytochrome c oxidase subunit VIc COX6C 1345 NM_004374 0006091 // generation of precursor metabolites and energy // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004129 // cytochrome-c oxidase activity // inferred from electronic annotation 201755_at NM_006739 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006739.1 /DEF=Homo sapiens minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) (MCM5), mRNA. /FEA=mRNA /GEN=MCM5 /PROD=minichromosome maintenance deficient (S.cerevisiae) 5 (cell division cycle 46) /DB_XREF=gi:6981191 /UG=Hs.77171 minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46) /FL=gb:D83986.1 gb:BC000142.1 gb:BC003656.1 gb:NM_006739.1 NM_006739 minichromosome maintenance complex component 5 MCM5 4174 NM_006739 0006260 // DNA replication // not recorded /// 0006260 // DNA replication // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // not recorded 0000166 // nucleotide binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation 201756_at NM_002946 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002946.1 /DEF=Homo sapiens replication protein A2 (32kD) (RPA2), mRNA. /FEA=mRNA /GEN=RPA2 /PROD=replication protein A2 (32kD) /DB_XREF=gi:4506584 /UG=Hs.79411 replication protein A2 (32kD) /FL=gb:BC001630.1 gb:J05249.1 gb:NM_002946.1 NM_002946 replication protein A2, 32kDa RPA2 6118 NM_002946 0000718 // nucleotide-excision repair, DNA damage removal // not recorded /// 0006260 // DNA replication // inferred from electronic annotation /// 0006261 // DNA-dependent DNA replication // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005662 // DNA replication factor A complex // inferred from physical interaction /// 0005662 // DNA replication factor A complex // traceable author statement 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003697 // single-stranded DNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201757_at NM_004552 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004552.1 /DEF=Homo sapiens NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) (NDUFS5), mRNA. /FEA=mRNA /GEN=NDUFS5 /PROD=NADH dehydrogenase (ubiquinone) Fe-S protein 5(15kD) (NADH-coenzyme Q reductase) /DB_XREF=gi:4758789 /UG=Hs.80595 NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD) (NADH-coenzyme Q reductase) /FL=gb:BC001884.1 gb:AF020352.1 gb:AF047434.1 gb:NM_004552.1 NM_004552 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) /// ribosomal protein L10 NDUFS5 /// RPL10 4725 /// 6134 NM_004552 /// NM_006013 0006120 // mitochondrial electron transport, NADH to ubiquinone // non-traceable author statement /// 0006412 // translation // inferred from electronic annotation /// 0006412 // translation // inferred by curator /// 0006414 // translational elongation // not recorded /// 0006810 // transport // inferred from electronic annotation /// 0022900 // electron transport chain // inferred from electronic annotation /// 0032981 // mitochondrial respiratory chain complex I assembly // inferred from mutant phenotype 0005622 // intracellular // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005746 // mitochondrial respiratory chain // inferred from electronic annotation /// 0005747 // mitochondrial respiratory chain complex I // non-traceable author statement /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005829 // cytosol // not recorded /// 0005840 // ribosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0022625 // cytosolic large ribosomal subunit // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0003735 // structural constituent of ribosome // inferred from direct assay /// 0003735 // structural constituent of ribosome // inferred from electronic annotation /// 0008137 // NADH dehydrogenase (ubiquinone) activity // non-traceable author statement 201758_at NM_006292 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006292.1 /DEF=Homo sapiens tumor susceptibility gene 101 (TSG101), mRNA. /FEA=mRNA /GEN=TSG101 /PROD=tumor susceptibility gene 101 /DB_XREF=gi:5454139 /UG=Hs.118910 tumor susceptibility gene 101 /FL=gb:BC002487.1 gb:U82130.1 gb:NM_006292.1 NM_006292 tumor susceptibility gene 101 TSG101 7251 NM_006292 0001558 // regulation of cell growth // inferred from electronic annotation /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043162 // ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway // inferred from direct assay /// 0043687 // post-translational protein modification // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0046755 // non-lytic virus budding // inferred from mutant phenotype /// 0051246 // regulation of protein metabolic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005770 // late endosome // inferred from mutant phenotype /// 0005771 // multivesicular body // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation 0003677 // DNA binding // traceable author statement /// 0003714 // transcription corepressor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0019787 // small conjugating protein ligase activity // inferred from electronic annotation /// 0043130 // ubiquitin binding // traceable author statement 201759_at AW247323 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW247323 /FEA=EST /DB_XREF=gi:6590316 /DB_XREF=est:2819524.3prime /CLONE=IMAGE:2819524 /UG=Hs.12570 tubulin-specific chaperone d /FL=gb:BC003094.1 gb:AB023205.1 gb:NM_005993.2 AW247323 tubulin folding cofactor D TBCD 6904 NM_005993 0006457 // protein folding // traceable author statement /// 0007025 // beta-tubulin folding // traceable author statement 0005874 // microtubule // traceable author statement 0005488 // binding // inferred from electronic annotation /// 0051087 // chaperone binding // traceable author statement 201760_s_at NM_018639 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018639.1 /DEF=Homo sapiens CS box-containing WD protein (LOC55884), mRNA. /FEA=mRNA /GEN=LOC55884 /PROD=CS box-containing WD protein /DB_XREF=gi:8923880 /UG=Hs.136644 CS box-containing WD protein /FL=gb:AF229181.1 gb:AF163324.1 gb:NM_018639.1 NM_018639 WD repeat and SOCS box-containing 2 WSB2 55884 NM_018639 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007242 // intracellular signaling cascade // inferred from electronic annotation 201761_at NM_006636 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006636.2 /DEF=Homo sapiens methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (MTHFD2), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=MTHFD2 /PROD=methylene tetrahydrofolate dehydrogenase (NAD+dependent), methenyltetrahydrofolate cyclohydrolase,precursor /DB_XREF=gi:13699869 /UG=Hs.154672 methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase /FL=gb:NM_006636.2 NM_006636 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase MTHFD2 10797 NM_001040409 /// NM_006636 0006730 // one-carbon compound metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009396 // folic acid and derivative biosynthetic process // inferred from electronic annotation /// 0046653 // tetrahydrofolate metabolic process // inferred from direct assay /// 0055114 // oxidation reduction // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from sequence or structural similarity 0000287 // magnesium ion binding // inferred from direct assay /// 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003824 // catalytic activity // inferred from electronic annotation /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // inferred from sequence or structural similarity /// 0004477 // methenyltetrahydrofolate cyclohydrolase activity // inferred from electronic annotation /// 0004487 // methylenetetrahydrofolate dehydrogenase (NAD+) activity // inferred from direct assay /// 0004487 // methylenetetrahydrofolate dehydrogenase (NAD+) activity // inferred from electronic annotation /// 0004488 // methylenetetrahydrofolate dehydrogenase (NADP+) activity // inferred from direct assay /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0042301 // phosphate binding // inferred from direct assay 201762_s_at NM_002818 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002818.1 /DEF=Homo sapiens proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (PSME2), mRNA. /FEA=mRNA /GEN=PSME2 /PROD=proteasome (prosome, macropain) activatorsubunit 2 (PA28 beta) /DB_XREF=gi:4506236 /UG=Hs.179774 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) /FL=gb:D45248.1 gb:BC004368.1 gb:NM_002818.1 NM_002818 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) PSME2 5721 NM_002818 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // not recorded /// 0051436 // negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded /// 0051437 // positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle // not recorded 0000502 // proteasome complex // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0008537 // proteasome activator complex // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0008538 // proteasome activator activity // inferred from electronic annotation 201763_s_at NM_001350 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001350.1 /DEF=Homo sapiens death-associated protein 6 (DAXX), mRNA. /FEA=mRNA /GEN=DAXX /PROD=death-associated protein 6 /DB_XREF=gi:4503256 /UG=Hs.180224 death-associated protein 6 /FL=gb:AF015956.2 gb:AF039136.1 gb:AF050179.1 gb:AF097742.1 gb:AB015051.1 gb:NM_001350.1 NM_001350 death-domain associated protein DAXX 1616 NM_001141969 /// NM_001141970 /// NM_001350 /// NR_024517 0000281 // cytokinesis after mitosis // inferred from electronic annotation /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006915 // apoptosis // traceable author statement /// 0006915 // apoptosis // inferred from electronic annotation /// 0007257 // activation of JNK activity // traceable author statement /// 0008625 // induction of apoptosis via death domain receptors // traceable author statement /// 0030521 // androgen receptor signaling pathway // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-dependent // inferred from direct assay 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from electronic annotation /// 0016605 // PML body // traceable author statement 0005057 // receptor signaling protein activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // inferred from electronic annotation /// 0031072 // heat shock protein binding // traceable author statement /// 0042802 // identical protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0050681 // androgen receptor binding // inferred from physical interaction 201764_at NM_024056 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024056.1 /DEF=Homo sapiens hypothetical protein MGC5576 (MGC5576), mRNA. /FEA=mRNA /GEN=MGC5576 /PROD=hypothetical protein MGC5576 /DB_XREF=gi:13129025 /UG=Hs.103834 hypothetical protein MGC5576 /FL=gb:BC000854.1 gb:NM_024056.1 NM_024056 transmembrane protein 106C TMEM106C 79022 NM_001143841 /// NM_001143842 /// NM_001143843 /// NM_001143844 /// NM_001143845 /// NM_024056 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201765_s_at AL523158 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL523158 /FEA=EST /DB_XREF=gi:12786651 /DB_XREF=est:AL523158 /CLONE=CS0DC001YM06 (3 prime) /UG=Hs.119403 hexosaminidase A (alpha polypeptide) /FL=gb:NM_000520.2 AL523158 hexosaminidase A (alpha polypeptide) HEXA 3073 NM_000520 0001501 // skeletal system development // inferred from electronic annotation /// 0005975 // carbohydrate metabolic process // inferred from electronic annotation /// 0006689 // ganglioside catabolic process // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from electronic annotation /// 0007605 // sensory perception of sound // inferred from electronic annotation /// 0007626 // locomotory behavior // inferred from electronic annotation /// 0007628 // adult walking behavior // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0019915 // sequestering of lipid // inferred from electronic annotation /// 0019953 // sexual reproduction // inferred from electronic annotation /// 0030203 // glycosaminoglycan metabolic process // inferred from electronic annotation /// 0042552 // myelination // inferred from electronic annotation /// 0050884 // neuromuscular process controlling posture // inferred from electronic annotation /// 0050885 // neuromuscular process controlling balance // inferred from electronic annotation 0005764 // lysosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004563 // beta-N-acetylhexosaminidase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0016798 // hydrolase activity, acting on glycosyl bonds // inferred from electronic annotation /// 0043169 // cation binding // inferred from electronic annotation /// 0046982 // protein heterodimerization activity // inferred from direct assay 201766_at AF304370 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AF304370.1 /DEF=Homo sapiens putative prostate cancer susceptibility protein HPC2ELAC2 mRNA, complete cds. /FEA=mRNA /PROD=putative prostate cancer susceptibility proteinHPC2ELAC2 /DB_XREF=gi:10880932 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1 AF304370 elaC homolog 2 (E. coli) ELAC2 60528 NM_018127 0008033 // tRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201767_s_at NM_018127 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_018127.2 /DEF=Homo sapiens putative prostate cancer susceptibility protein (HPC2), mRNA. /FEA=mRNA /GEN=HPC2 /PROD=putative prostate cancer susceptibility protein /DB_XREF=gi:11875212 /UG=Hs.12124 putative prostate cancer susceptibility protein /FL=gb:AF304370.1 gb:NM_018127.2 gb:BC001939.1 gb:BC004158.1 NM_018127 elaC homolog 2 (E. coli) ELAC2 60528 NM_018127 0008033 // tRNA processing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201768_s_at BC004467 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC004467.1 /DEF=Homo sapiens, KIAA0171 gene product, clone MGC:10257, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0171 gene product /DB_XREF=gi:13325306 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1 BC004467 clathrin interactor 1 CLINT1 9685 NM_014666 /// XM_001715730 /// XM_001723151 /// XM_001725023 0006897 // endocytosis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 201769_at NM_014666 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014666.1 /DEF=Homo sapiens KIAA0171 gene product (KIAA0171), mRNA. /FEA=mRNA /GEN=KIAA0171 /PROD=KIAA0171 gene product /DB_XREF=gi:7661967 /UG=Hs.155623 KIAA0171 gene product /FL=gb:D79993.1 gb:BC004467.1 gb:NM_014666.1 NM_014666 clathrin interactor 1 CLINT1 9685 NM_014666 /// XM_001715730 /// XM_001723151 /// XM_001725023 0006897 // endocytosis // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 201770_at NM_004596 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004596.1 /DEF=Homo sapiens small nuclear ribonucleoprotein polypeptide A (SNRPA), mRNA. /FEA=mRNA /GEN=SNRPA /PROD=small nuclear ribonucleoprotein polypeptide A /DB_XREF=gi:4759155 /UG=Hs.173255 small nuclear ribonucleoprotein polypeptide A /FL=gb:BC000405.1 gb:NM_004596.1 NM_004596 small nuclear ribonucleoprotein polypeptide A SNRPA 6626 NM_004596 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0000398 // nuclear mRNA splicing, via spliceosome // inferred by curator /// 0006397 // mRNA processing // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005681 // spliceosome // inferred from direct assay /// 0005681 // spliceosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201771_at NM_005698 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005698.1 /DEF=Homo sapiens secretory carrier membrane protein 3 (SCAMP3), mRNA. /FEA=mRNA /GEN=SCAMP3 /PROD=secretory carrier membrane protein 3 /DB_XREF=gi:5032076 /UG=Hs.200600 secretory carrier membrane protein 3 /FL=gb:BC000161.2 gb:BC005135.1 gb:AF005039.1 gb:NM_005698.1 NM_005698 secretory carrier membrane protein 3 SCAMP3 10067 NM_005698 /// NM_052837 0006810 // transport // inferred from electronic annotation /// 0006892 // post-Golgi vesicle-mediated transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201772_at NM_015878 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015878.1 /DEF=Homo sapiens antizyme inhibitor (LOC51582), mRNA. /FEA=mRNA /GEN=LOC51582 /PROD=antizyme inhibitor /DB_XREF=gi:7706219 /UG=Hs.223014 antizyme inhibitor /FL=gb:D88674.1 gb:NM_015878.1 NM_015878 antizyme inhibitor 1 AZIN1 51582 NM_015878 /// NM_148174 0006596 // polyamine biosynthetic process // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004857 // enzyme inhibitor activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008073 // ornithine decarboxylase inhibitor activity // inferred from electronic annotation 201773_at NM_015339 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015339.1 /DEF=Homo sapiens activity-dependent neuroprotective protein (ADNP), mRNA. /FEA=mRNA /GEN=ADNP /PROD=activity-dependent neuroprotective protein /DB_XREF=gi:12229216 /UG=Hs.3657 activity-dependent neuroprotective protein /FL=gb:AF250860.1 gb:NM_015339.1 NM_015339 activity-dependent neuroprotector homeobox ADNP 23394 NM_015339 /// NM_181442 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0043524 // negative regulation of neuron apoptosis // inferred from electronic annotation 0005615 // extracellular space // inferred from electronic annotation /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay 0003677 // DNA binding // inferred from electronic annotation /// 0003682 // chromatin binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201774_s_at AK022511 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK022511.1 /DEF=Homo sapiens cDNA FLJ12449 fis, clone NT2RM1000314, highly similar to Human mRNA for KIAA0159 gene. /FEA=mRNA /DB_XREF=gi:10433940 /UG=Hs.5719 chromosome condensation-related SMC-associated protein 1 /FL=gb:NM_014865.1 gb:D63880.1 AK022511 non-SMC condensin I complex, subunit D2 NCAPD2 9918 NM_014865 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0007076 // mitotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0000793 // condensed chromosome // inferred from direct assay /// 0000797 // condensin core heterodimer // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // non-traceable author statement /// 0005737 // cytoplasm // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0042393 // histone binding // non-traceable author statement 201775_s_at AA676790 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AA676790 /FEA=EST /DB_XREF=gi:2657312 /DB_XREF=est:zj64h12.s1 /CLONE=IMAGE:455111 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 AA676790 KIAA0494 KIAA0494 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation 201776_s_at AK001487 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AK001487.1 /DEF=Homo sapiens cDNA FLJ10625 fis, clone NT2RP2005540, highly similar to Homo sapiens mRNA for KIAA0494 protein. /FEA=mRNA /DB_XREF=gi:7022773 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 AK001487 KIAA0494 KIAA0494 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation 201777_s_at BC002525 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC002525.1 /DEF=Homo sapiens, KIAA0494 gene product, clone MGC:1949, mRNA, complete cds. /FEA=mRNA /PROD=KIAA0494 gene product /DB_XREF=gi:12803404 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 BC002525 KIAA0494 KIAA0494 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation 201778_s_at NM_014774 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014774.1 /DEF=Homo sapiens KIAA0494 gene product (KIAA0494), mRNA. /FEA=mRNA /GEN=KIAA0494 /PROD=KIAA0494 gene product /DB_XREF=gi:7662159 /UG=Hs.62515 KIAA0494 gene product /FL=gb:BC002525.1 gb:AB007963.1 gb:NM_014774.1 NM_014774 KIAA0494 KIAA0494 9813 NM_014774 0005509 // calcium ion binding // inferred from electronic annotation 201779_s_at AF070558 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF070558.1 /DEF=Homo sapiens clone 24450 RING zinc finger protein RZF mRNA, complete cds. /FEA=mRNA /PROD=RING zinc finger protein RZF /DB_XREF=gi:3387924 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1 AF070558 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183383 /// NM_183384 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201780_s_at NM_007282 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007282.1 /DEF=Homo sapiens ring finger protein 13 (RNF13), mRNA. /FEA=mRNA /GEN=RNF13 /PROD=ring finger protein 13 /DB_XREF=gi:6005863 /UG=Hs.6900 ring finger protein 13 /FL=gb:AF037204.1 gb:AF070558.1 gb:NM_007282.1 NM_007282 ring finger protein 13 RNF13 11342 NM_007282 /// NM_183381 /// NM_183383 /// NM_183384 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201781_s_at AL558532 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL558532 /FEA=EST /DB_XREF=gi:12903142 /DB_XREF=est:AL558532 /CLONE=CS0DJ006YJ15 (5 prime) /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1 AL558532 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0006457 // protein folding // inferred from electronic annotation /// 0022417 // protein maturation via protein folding // inferred from direct assay /// 0043681 // protein import into mitochondrion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from direct assay 201782_s_at NM_003977 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003977.1 /DEF=Homo sapiens aryl hydrocarbon receptor-interacting protein (AIP), mRNA. /FEA=mRNA /GEN=AIP /PROD=aryl hydrocarbon receptor-interacting protein /DB_XREF=gi:4502008 /UG=Hs.75305 aryl hydrocarbon receptor-interacting protein /FL=gb:U31913.1 gb:U78521.1 gb:NM_003977.1 NM_003977 aryl hydrocarbon receptor interacting protein AIP 9049 NM_003977 0006457 // protein folding // inferred from electronic annotation /// 0022417 // protein maturation via protein folding // inferred from direct assay /// 0043681 // protein import into mitochondrion // inferred from direct assay 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement 0003713 // transcription coactivator activity // traceable author statement /// 0004871 // signal transducer activity // traceable author statement /// 0004872 // receptor activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0051082 // unfolded protein binding // inferred from direct assay 201783_s_at NM_021975 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021975.1 /DEF=Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) (RELA), mRNA. /FEA=mRNA /GEN=RELA /PROD=v-rel avian reticuloendotheliosis viral oncogenehomolog A (nuclear factor of kappa light polypeptide geneenhancer in B-cells 3 (p65)) /DB_XREF=gi:11496238 /UG=Hs.75569 v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)) /FL=gb:NM_021975.1 gb:L19067.1 NM_021975 v-rel reticuloendotheliosis viral oncogene homolog A (avian) RELA 5970 NM_021975 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006916 // anti-apoptosis // inferred from direct assay /// 0006954 // inflammatory response // inferred from direct assay /// 0006968 // cellular defense response // non-traceable author statement /// 0010033 // response to organic substance // inferred from direct assay /// 0010224 // response to UV-B // inferred from direct assay /// 0019221 // cytokine-mediated signaling pathway // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB cascade // inferred from expression pattern /// 0045449 // regulation of transcription // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051607 // defense response to virus // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005667 // transcription factor complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0003677 // DNA binding // inferred from direct assay /// 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003700 // transcription factor activity // inferred from direct assay /// 0003705 // RNA polymerase II transcription factor activity, enhancer binding // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // inferred from physical interaction /// 0019901 // protein kinase binding // inferred from physical interaction /// 0042301 // phosphate binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from direct assay /// 0042802 // identical protein binding // inferred from physical interaction /// 0047485 // protein N-terminus binding // inferred from physical interaction /// 0051059 // NF-kappaB binding // inferred from physical interaction 201784_s_at NM_014267 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014267.1 /DEF=Homo sapiens small acidic protein (IMAGE145052), mRNA. /FEA=mRNA /GEN=IMAGE145052 /PROD=small acidic protein /DB_XREF=gi:7657233 /UG=Hs.78050 small acidic protein /FL=gb:U51678.1 gb:NM_014267.1 NM_014267 chromosome 11 open reading frame 58 C11orf58 10944 NM_001142705 /// NM_014267 201785_at NM_002933 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002933.1 /DEF=Homo sapiens ribonuclease, RNase A family, 1 (pancreatic) (RNASE1), mRNA. /FEA=mRNA /GEN=RNASE1 /PROD=ribonuclease, RNase A family, 1 (pancreatic) /DB_XREF=gi:4506546 /UG=Hs.78224 ribonuclease, RNase A family, 1 (pancreatic) /FL=gb:BC005324.1 gb:NM_002933.1 gb:D26129.1 NM_002933 ribonuclease, RNase A family, 1 (pancreatic) RNASE1 6035 NM_002933 /// NM_198232 /// NM_198234 /// NM_198235 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0003676 // nucleic acid binding // inferred from electronic annotation /// 0004518 // nuclease activity // inferred from electronic annotation /// 0004519 // endonuclease activity // inferred from electronic annotation /// 0004522 // pancreatic ribonuclease activity // traceable author statement /// 0004522 // pancreatic ribonuclease activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201786_s_at NM_001111 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001111.2 /DEF=Homo sapiens adenosine deaminase, RNA-specific (ADAR), transcript variant ADAR-a, mRNA. /FEA=mRNA /GEN=ADAR /PROD=adenosine deaminase, RNA-specific, isoformADAR-a /DB_XREF=gi:7669471 /UG=Hs.7957 adenosine deaminase, RNA-specific /FL=gb:U10439.1 gb:NM_001111.2 gb:U18121.1 NM_001111 adenosine deaminase, RNA-specific ADAR 103 NM_001025107 /// NM_001111 /// NM_015840 /// NM_015841 0006396 // RNA processing // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0016553 // base conversion or substitution editing // inferred from direct assay /// 0031047 // gene silencing by RNA // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // inferred from electronic annotation /// 0003726 // double-stranded RNA adenosine deaminase activity // non-traceable author statement /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from electronic annotation /// 0003726 // double-stranded RNA adenosine deaminase activity // inferred from direct assay /// 0003726 // double-stranded RNA adenosine deaminase activity // traceable author statement /// 0004000 // adenosine deaminase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201787_at NM_001996 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001996.1 /DEF=Homo sapiens fibulin 1 (FBLN1), transcript variant C, mRNA. /FEA=mRNA /GEN=FBLN1 /PROD=fibulin 1 isoform C precursor /DB_XREF=gi:4503662 /UG=Hs.79732 fibulin 1 /FL=gb:NM_001996.1 NM_001996 fibulin 1 /// similar to Fibulin 1 FBLN1 /// LOC100133843 100133843 /// 2192 NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 /// XM_001718348 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005576 // extracellular region // non-traceable author statement /// 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // traceable author statement /// 0005625 // soluble fraction // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay 0005201 // extracellular matrix structural constituent // traceable author statement /// 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201788_at NM_007372 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007372.1 /DEF=Homo sapiens RNA helicase-related protein (RNAHP), mRNA. /FEA=mRNA /GEN=RNAHP /PROD=RNA helicase-related protein /DB_XREF=gi:11321631 /UG=Hs.8765 RNA helicase-related protein /FL=gb:NM_007372.1 gb:AF083255.1 NM_007372 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 DDX42 11325 NM_007372 /// NM_203499 0005634 // nucleus // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0004386 // helicase activity // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008026 // ATP-dependent helicase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201789_at BC000637 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BC000637.1 /DEF=Homo sapiens, CGI-86 protein, clone MGC:681, mRNA, complete cds. /FEA=mRNA /PROD=CGI-86 protein /DB_XREF=gi:12653704 /UG=Hs.109201 CGI-86 protein /FL=gb:BC000637.1 gb:AF151844.1 gb:NM_016029.1 BC000637 dehydrogenase/reductase (SDR family) member 7 DHRS7 51635 NM_016029 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation 201790_s_at AW150953 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW150953 /FEA=EST /DB_XREF=gi:6198851 /DB_XREF=est:xg42f09.x1 /CLONE=IMAGE:2630249 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1 AW150953 7-dehydrocholesterol reductase DHCR7 1717 NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // not recorded /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from electronic annotation 201791_s_at NM_001360 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001360.1 /DEF=Homo sapiens 7-dehydrocholesterol reductase (DHCR7), mRNA. /FEA=mRNA /GEN=DHCR7 /PROD=7-dehydrocholesterol reductase /DB_XREF=gi:4503320 /UG=Hs.11806 7-dehydrocholesterol reductase /FL=gb:BC000054.1 gb:AF034544.1 gb:AF067127.1 gb:AF096305.1 gb:NM_001360.1 NM_001360 7-dehydrocholesterol reductase DHCR7 1717 NM_001360 0001568 // blood vessel development // inferred from electronic annotation /// 0006694 // steroid biosynthetic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from mutant phenotype /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0009791 // post-embryonic development // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0005640 // nuclear outer membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // not recorded /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047598 // 7-dehydrocholesterol reductase activity // not recorded /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from direct assay /// 0047598 // 7-dehydrocholesterol reductase activity // inferred from electronic annotation 201792_at NM_001129 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001129.2 /DEF=Homo sapiens AE-binding protein 1 (AEBP1), mRNA. /FEA=mRNA /GEN=AEBP1 /PROD=adipocyte enhancer binding protein 1 precursor /DB_XREF=gi:4755145 /UG=Hs.118397 AE-binding protein 1 /FL=gb:D86479.1 gb:AF053944.1 gb:NM_001129.2 NM_001129 AE binding protein 1 AEBP1 165 NM_001129 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0004180 // carboxypeptidase activity // inferred from electronic annotation /// 0004181 // metallocarboxypeptidase activity // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation 201793_x_at BF509099 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF509099 /FEA=EST /DB_XREF=gi:11592397 /DB_XREF=est:UI-H-BI4-aou-e-05-0-UI.s1 /CLONE=IMAGE:3086288 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1 BF509099 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) SMG7 9887 NM_173156 /// NM_201568 /// NM_201569 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201794_s_at NM_014837 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014837.1 /DEF=Homo sapiens KIAA0250 gene product (KIAA0250), mRNA. /FEA=mRNA /GEN=KIAA0250 /PROD=KIAA0250 gene product /DB_XREF=gi:7662023 /UG=Hs.15087 KIAA0250 gene product /FL=gb:D87437.1 gb:NM_014837.1 NM_014837 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) SMG7 9887 NM_173156 /// NM_201568 /// NM_201569 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // traceable author statement /// 0000184 // nuclear-transcribed mRNA catabolic process, nonsense-mediated decay // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0035303 // regulation of dephosphorylation // traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0051721 // protein phosphatase 2A binding // inferred from direct assay 201795_at NM_002296 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002296.1 /DEF=Homo sapiens lamin B receptor (LBR), mRNA. /FEA=mRNA /GEN=LBR /PROD=lamin B receptor /DB_XREF=gi:4504960 /UG=Hs.152931 lamin B receptor /FL=gb:L25931.1 gb:NM_002296.1 NM_002296 lamin B receptor LBR 3930 NM_002296 /// NM_194442 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // not recorded /// 0005637 // nuclear inner membrane // inferred from electronic annotation /// 0005639 // integral to nuclear inner membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay /// 0016021 // integral to membrane // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005521 // lamin binding // traceable author statement /// 0050613 // delta14-sterol reductase activity // not recorded 201796_s_at BE790854 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE790854 /FEA=EST /DB_XREF=gi:10212052 /DB_XREF=est:601582271F1 /CLONE=IMAGE:3936952 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1 BE790854 valyl-tRNA synthetase VARS 7407 NM_006295 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0004832 // valine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 201797_s_at NM_006295 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006295.1 /DEF=Homo sapiens valyl-tRNA synthetase 2 (VARS2), mRNA. /FEA=mRNA /GEN=VARS2 /PROD=valyl-tRNA synthetase 2 /DB_XREF=gi:5454157 /UG=Hs.159637 valyl-tRNA synthetase 2 /FL=gb:NM_006295.1 NM_006295 valyl-tRNA synthetase VARS 7407 NM_006295 0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // non-traceable author statement /// 0006418 // tRNA aminoacylation for protein translation // inferred from electronic annotation /// 0006438 // valyl-tRNA aminoacylation // inferred from electronic annotation /// 0006952 // defense response // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0007584 // response to nutrient // inferred from electronic annotation 0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0004812 // aminoacyl-tRNA ligase activity // inferred from electronic annotation /// 0004832 // valine-tRNA ligase activity // inferred from direct assay /// 0004832 // valine-tRNA ligase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0005524 // ATP binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0051059 // NF-kappaB binding // inferred from electronic annotation 201798_s_at NM_013451 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_013451.1 /DEF=Homo sapiens fer-1 (C.elegans)-like 3 (myoferlin) (FER1L3), mRNA. /FEA=mRNA /GEN=FER1L3 /PROD=fer-1 (C.elegans)-like 3 (myoferlin) /DB_XREF=gi:7305052 /UG=Hs.234680 fer-1 (C.elegans)-like 3 (myoferlin) /FL=gb:AF182316.1 gb:NM_013451.1 NM_013451 myoferlin MYOF 26509 NM_013451 /// NM_133337 0006936 // muscle contraction // traceable author statement /// 0008015 // blood circulation // traceable author statement 0005634 // nucleus // inferred from electronic annotation /// 0005635 // nuclear envelope // traceable author statement /// 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030659 // cytoplasmic vesicle membrane // inferred from electronic annotation /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201799_s_at AI927993 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI927993 /FEA=EST /DB_XREF=gi:5663957 /DB_XREF=est:wo92c11.x1 /CLONE=IMAGE:2462804 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1 AI927993 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0008142 // oxysterol binding // traceable author statement 201800_s_at AF185696 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF185696.1 /DEF=Homo sapiens oxysterol-binding protein 1 (OSBP1) mRNA, complete cds. /FEA=mRNA /GEN=OSBP1 /PROD=oxysterol-binding protein 1 /DB_XREF=gi:10441379 /UG=Hs.24734 oxysterol binding protein /FL=gb:AF185696.1 gb:M86917.1 gb:NM_002556.1 AF185696 oxysterol binding protein OSBP 5007 NM_002556 0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0008142 // oxysterol binding // traceable author statement 201801_s_at AF079117 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF079117.1 /DEF=Homo sapiens equilibrative NBMPR-sensitive nucleoside transporter (ENT1) mRNA, complete cds. /FEA=mRNA /GEN=ENT1 /PROD=equilibrative NBMPR-sensitive nucleosidetransporter /DB_XREF=gi:3694939 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1 AF079117 solute carrier family 29 (nucleoside transporters), member 1 SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015858 // nucleoside transport // traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005337 // nucleoside transmembrane transporter activity // traceable author statement /// 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201802_at NM_004955 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004955.1 /DEF=Homo sapiens solute carrier family 29 (nucleoside transporters), member 1 (SLC29A1), mRNA. /FEA=mRNA /GEN=SLC29A1 /PROD=solute carrier family 29 (nucleosidetransporters), member 1 /DB_XREF=gi:4826715 /UG=Hs.25450 solute carrier family 29 (nucleoside transporters), member 1 /FL=gb:BC001382.1 gb:U81375.1 gb:AF079117.1 gb:NM_004955.1 NM_004955 solute carrier family 29 (nucleoside transporters), member 1 SLC29A1 2030 NM_001078174 /// NM_001078175 /// NM_001078176 /// NM_001078177 /// NM_004955 0006139 // nucleobase, nucleoside, nucleotide and nucleic acid metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0015858 // nucleoside transport // traceable author statement 0005624 // membrane fraction // traceable author statement /// 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005337 // nucleoside transmembrane transporter activity // traceable author statement /// 0005337 // nucleoside transmembrane transporter activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201803_at NM_000938 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000938.1 /DEF=Homo sapiens polymerase (RNA) II (DNA directed) polypeptide B (140kD) (POLR2B), mRNA. /FEA=mRNA /GEN=POLR2B /PROD=polymerase (RNA) II (DNA directed) polypeptide B(140kD) /DB_XREF=gi:4505940 /UG=Hs.296014 polymerase (RNA) II (DNA directed) polypeptide B (140kD) /FL=gb:NM_000938.1 NM_000938 polymerase (RNA) II (DNA directed) polypeptide B, 140kDa POLR2B 5431 NM_000938 0000398 // nuclear mRNA splicing, via spliceosome // not recorded /// 0006350 // transcription // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // not recorded /// 0006368 // RNA elongation from RNA polymerase II promoter // not recorded 0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // not recorded /// 0005665 // DNA-directed RNA polymerase II, core complex // traceable author statement 0000287 // magnesium ion binding // inferred from electronic annotation /// 0003677 // DNA binding // traceable author statement /// 0003677 // DNA binding // inferred from electronic annotation /// 0003899 // DNA-directed RNA polymerase activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0016779 // nucleotidyltransferase activity // inferred from electronic annotation /// 0032549 // ribonucleoside binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201804_x_at NM_001281 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001281.1 /DEF=Homo sapiens cytoskeleton-associated protein 1 (CKAP1), mRNA. /FEA=mRNA /GEN=CKAP1 /PROD=CKAP1 /DB_XREF=gi:4502848 /UG=Hs.31053 cytoskeleton-associated protein 1 /FL=gb:AF013488.1 gb:NM_001281.1 gb:D49738.1 NM_001281 tubulin folding cofactor B TBCB 1155 NM_001281 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // traceable author statement 0005515 // protein binding // inferred from physical interaction 201805_at NM_002733 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002733.1 /DEF=Homo sapiens protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), mRNA. /FEA=mRNA /GEN=PRKAG1 /PROD=protein kinase, AMP-activated, gamma 1non-catalytic subunit /DB_XREF=gi:4506060 /UG=Hs.3136 protein kinase, AMP-activated, gamma 1 non-catalytic subunit /FL=gb:BC000358.1 gb:U42412.1 gb:NM_002733.1 NM_002733 protein kinase, AMP-activated, gamma 1 non-catalytic subunit PRKAG1 5571 NM_002733 /// NM_212461 0006110 // regulation of glycolysis // traceable author statement /// 0006468 // protein amino acid phosphorylation // traceable author statement /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007283 // spermatogenesis // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // traceable author statement 0005634 // nucleus // inferred from electronic annotation 0004691 // cAMP-dependent protein kinase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0008603 // cAMP-dependent protein kinase regulator activity // traceable author statement /// 0016301 // kinase activity // inferred from electronic annotation /// 0019901 // protein kinase binding // inferred from direct assay 201806_s_at NM_007245 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_007245.1 /DEF=Homo sapiens ataxin 2 related protein (A2LP), transcript variant 1, mRNA. /FEA=mRNA /GEN=A2LP /PROD=ataxin 2 related protein, isoform 1 /DB_XREF=gi:6005698 /UG=Hs.43509 ataxin 2 related protein /FL=gb:AF034373.1 gb:NM_007245.1 NM_007245 ataxin 2-like ATXN2L 11273 NM_007245 /// NM_145714 /// NM_148414 /// NM_148415 /// NM_148416 0016020 // membrane // inferred from electronic annotation 201807_at NM_004896 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004896.1 /DEF=Homo sapiens vacuolar protein sorting 26 (yeast homolog) (VPS26), mRNA. /FEA=mRNA /GEN=VPS26 /PROD=vacuolar protein sorting 26 (yeast homolog) /DB_XREF=gi:4758509 /UG=Hs.67052 vacuolar protein sorting 26 (yeast homolog) /FL=gb:AF054179.1 gb:NM_004896.1 gb:AF175266.1 NM_004896 vacuolar protein sorting 26 homolog A (S. pombe) VPS26A 9559 NM_001035260 /// NM_004896 0006810 // transport // inferred from electronic annotation /// 0007034 // vacuolar transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0042147 // retrograde transport, endosome to Golgi // non-traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0010008 // endosome membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0030904 // retromer complex // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // non-traceable author statement 201808_s_at BE732652 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE732652 /FEA=EST /DB_XREF=gi:10146644 /DB_XREF=est:601571266F1 /CLONE=IMAGE:3925601 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1 BE732652 endoglin ENG 2022 NM_000118 /// NM_001114753 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0045449 // regulation of transcription // inferred from mutant phenotype /// 0048745 // smooth muscle development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity 0005615 // extracellular space // traceable author statement /// 0005624 // membrane fraction // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor complex // inferred by curator 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042301 // phosphate binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 201809_s_at NM_000118 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000118.1 /DEF=Homo sapiens endoglin (Osler-Rendu-Weber syndrome 1) (ENG), mRNA. /FEA=mRNA /GEN=ENG /PROD=endoglin precursor /DB_XREF=gi:4557554 /UG=Hs.76753 endoglin (Osler-Rendu-Weber syndrome 1) /FL=gb:NM_000118.1 NM_000118 endoglin ENG 2022 NM_000118 /// NM_001114753 0001525 // angiogenesis // inferred from electronic annotation /// 0001569 // patterning of blood vessels // inferred from sequence or structural similarity /// 0001570 // vasculogenesis // inferred from mutant phenotype /// 0001947 // heart looping // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0022009 // central nervous system vasculogenesis // inferred from mutant phenotype /// 0030509 // BMP signaling pathway // traceable author statement /// 0030513 // positive regulation of BMP signaling pathway // inferred from direct assay /// 0045449 // regulation of transcription // inferred from mutant phenotype /// 0048745 // smooth muscle development // inferred from sequence or structural similarity /// 0048844 // artery morphogenesis // inferred from sequence or structural similarity /// 0048845 // venous blood vessel morphogenesis // inferred from sequence or structural similarity 0005615 // extracellular space // traceable author statement /// 0005624 // membrane fraction // inferred from direct assay /// 0009897 // external side of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0070022 // transforming growth factor beta receptor complex // inferred by curator 0005114 // type II transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0005534 // galactose binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from direct assay /// 0005539 // glycosaminoglycan binding // inferred from sequence or structural similarity /// 0034713 // type I transforming growth factor beta receptor binding // inferred from sequence or structural similarity /// 0042301 // phosphate binding // inferred from sequence or structural similarity /// 0042803 // protein homodimerization activity // inferred from sequence or structural similarity /// 0048185 // activin binding // traceable author statement /// 0050431 // transforming growth factor beta binding // inferred from physical interaction 201810_s_at AL562152 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL562152 /FEA=EST /DB_XREF=gi:12910291 /DB_XREF=est:AL562152 /CLONE=CS0DC001YK23 (3 prime) /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1 AL562152 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201811_x_at NM_004844 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004844.1 /DEF=Homo sapiens SH3-domain binding protein 5 (BTK-associated) (SH3BP5), mRNA. /FEA=mRNA /GEN=SH3BP5 /PROD=SH3-domain binding protein 5 (BTK-associated) /DB_XREF=gi:4759057 /UG=Hs.109150 SH3-domain binding protein 5 (BTK-associated) /FL=gb:AB005047.1 gb:NM_004844.1 NM_004844 SH3-domain binding protein 5 (BTK-associated) SH3BP5 9467 NM_001018009 /// NM_004844 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from direct assay 0005737 // cytoplasm // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation 0004860 // protein kinase inhibitor activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0017124 // SH3 domain binding // inferred from electronic annotation 201812_s_at NM_019059 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_019059.1 /DEF=Homo sapiens 6.2 kd protein (LOC54543), mRNA. /FEA=mRNA /GEN=LOC54543 /PROD=6.2 kd protein /DB_XREF=gi:9506858 /UG=Hs.112318 6.2 kd protein /FL=gb:BC001732.1 gb:AF150733.1 gb:NM_019059.1 NM_019059 chromosome 4 open reading frame 46 /// translocase of outer mitochondrial membrane 7 homolog (yeast) C4orf46 /// TOMM7 201725 /// 54543 NM_001008393 /// NM_019059 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043681 // protein import into mitochondrion // traceable author statement 0005739 // mitochondrion // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005742 // mitochondrial outer membrane translocase complex // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0008320 // protein transmembrane transporter activity // traceable author statement /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201813_s_at AI654161 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI654161 /FEA=EST /DB_XREF=gi:4738140 /DB_XREF=est:ty62e04.x1 /CLONE=IMAGE:2283678 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI654161 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_001716616 /// XM_001718151 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201814_at AI300084 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI300084 /FEA=EST /DB_XREF=gi:3959430 /DB_XREF=est:qn59f02.x1 /CLONE=IMAGE:1902555 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 AI300084 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_001716616 /// XM_001718151 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201815_s_at NM_014744 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014744.1 /DEF=Homo sapiens KIAA0210 gene product (KIAA0210), mRNA. /FEA=mRNA /GEN=KIAA0210 /PROD=KIAA0210 gene product /DB_XREF=gi:7661997 /UG=Hs.115740 KIAA0210 gene product /FL=gb:D86965.1 gb:NM_014744.1 NM_014744 TBC1 domain family, member 5 TBC1D5 9779 NM_001134380 /// NM_001134381 /// NM_014744 /// XM_001716616 /// XM_001718151 0032313 // regulation of Rab GTPase activity // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005097 // Rab GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201816_s_at NM_001483 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001483.1 /DEF=Homo sapiens glioblastoma amplified sequence (GBAS), mRNA. /FEA=mRNA /GEN=GBAS /PROD=glioblastoma amplified sequence /DB_XREF=gi:4503936 /UG=Hs.152707 glioblastoma amplified sequence /FL=gb:BC000732.1 gb:BC001837.1 gb:AF029786.1 gb:NM_001483.1 NM_001483 glioblastoma amplified sequence GBAS 2631 NM_001483 0005624 // membrane fraction // traceable author statement /// 0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005887 // integral to plasma membrane // traceable author statement 201817_at NM_014671 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014671.1 /DEF=Homo sapiens KIAA0010 gene product (KIAA0010), mRNA. /FEA=mRNA /GEN=KIAA0010 /PROD=KIAA0010 gene product /DB_XREF=gi:7661855 /UG=Hs.155287 KIAA0010 gene product /FL=gb:D13635.1 gb:NM_014671.1 NM_014671 ubiquitin protein ligase E3C UBE3C 9690 NM_014671 0000209 // protein polyubiquitination // inferred from direct assay /// 0006464 // protein modification process // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation 0005622 // intracellular // inferred by curator /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation 0004842 // ubiquitin-protein ligase activity // inferred from direct assay /// 0005515 // protein binding // inferred from physical interaction /// 0016874 // ligase activity // inferred from electronic annotation /// 0016881 // acid-amino acid ligase activity // inferred from electronic annotation 201818_at NM_024830 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024830.1 /DEF=Homo sapiens hypothetical protein FLJ12443 (FLJ12443), mRNA. /FEA=mRNA /GEN=FLJ12443 /PROD=hypothetical protein FLJ12443 /DB_XREF=gi:13376233 /UG=Hs.179882 hypothetical protein FLJ12443 /FL=gb:NM_024830.1 NM_024830 lysophosphatidylcholine acyltransferase 1 LPCAT1 79888 NM_024830 /// XM_001717124 /// XM_001720496 0008152 // metabolic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from sequence or structural similarity /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation 0000139 // Golgi membrane // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from sequence or structural similarity /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005509 // calcium ion binding // inferred from electronic annotation /// 0008415 // acyltransferase activity // inferred from electronic annotation /// 0016740 // transferase activity // inferred from electronic annotation /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from sequence or structural similarity /// 0047184 // 1-acylglycerophosphocholine O-acyltransferase activity // inferred from electronic annotation 201819_at NM_005505 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005505.1 /DEF=Homo sapiens CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 (CD36L1), mRNA. /FEA=mRNA /GEN=CD36L1 /PROD=CD36 antigen (collagen type I receptor,thrombospondin receptor)-like 1 /DB_XREF=gi:5031628 /UG=Hs.180616 CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1 /FL=gb:NM_005505.1 NM_005505 scavenger receptor class B, member 1 SCARB1 949 NM_001082959 /// NM_005505 0006810 // transport // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005886 // plasma membrane // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0004872 // receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // traceable author statement /// 0005215 // transporter activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201820_at NM_000424 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000424.1 /DEF=Homo sapiens keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) (KRT5), mRNA. /FEA=mRNA /GEN=KRT5 /PROD=keratin 5 (epidermolysis bullosa simplex,Dowling-MearaKobnerWeber-Cockayne types) /DB_XREF=gi:4557889 /UG=Hs.195850 keratin 5 (epidermolysis bullosa simplex, Dowling-MearaKobnerWeber-Cockayne types) /FL=gb:M21389.1 gb:NM_000424.1 NM_000424 keratin 5 KRT5 3852 NM_000424 0008544 // epidermis development // traceable author statement /// 0030855 // epithelial cell differentiation // inferred from electronic annotation /// 0050680 // negative regulation of epithelial cell proliferation // inferred from electronic annotation 0005882 // intermediate filament // inferred from electronic annotation /// 0005882 // intermediate filament // traceable author statement /// 0045095 // keratin filament // inferred from direct assay /// 0045095 // keratin filament // inferred from electronic annotation 0005198 // structural molecule activity // inferred from electronic annotation /// 0005200 // structural constituent of cytoskeleton // traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201821_s_at BC004439 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC004439.1 /DEF=Homo sapiens, translocase of inner mitochondrial membrane 17 (yeast) homolog A, clone MGC:4031, mRNA, complete cds. /FEA=mRNA /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:13325239 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1 BC004439 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201822_at NM_006335 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006335.1 /DEF=Homo sapiens translocase of inner mitochondrial membrane 17 (yeast) homolog A (TIM17), mRNA. /FEA=mRNA /GEN=TIM17 /PROD=translocase of inner mitochondrial membrane 17(yeast) homolog A /DB_XREF=gi:5454119 /UG=Hs.20716 translocase of inner mitochondrial membrane 17 (yeast) homolog A /FL=gb:BC004439.1 gb:AF106622.1 gb:NM_006335.1 NM_006335 translocase of inner mitochondrial membrane 17 homolog A (yeast) TIMM17A 10440 NM_006335 0006626 // protein targeting to mitochondrion // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0065002 // intracellular protein transmembrane transport // inferred from electronic annotation 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005744 // mitochondrial inner membrane presequence translocase complex // traceable author statement /// 0005744 // mitochondrial inner membrane presequence translocase complex // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement /// 0016021 // integral to membrane // inferred from electronic annotation 0008565 // protein transporter activity // inferred from electronic annotation /// 0015450 // P-P-bond-hydrolysis-driven protein transmembrane transporter activity // inferred from electronic annotation 201823_s_at NM_004290 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004290.1 /DEF=Homo sapiens ring finger protein 14 (RNF14), mRNA. /FEA=mRNA /GEN=RNF14 /PROD=ring finger protein 14 /DB_XREF=gi:4757761 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1 NM_004290 ring finger protein 14 RNF14 9604 NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol stimulus // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-dependent // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 201824_at AB022663 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB022663.1 /DEF=Homo sapiens HFB30 mRNA, complete cds. /FEA=mRNA /GEN=HFB30 /DB_XREF=gi:5019617 /UG=Hs.215857 ring finger protein 14 /FL=gb:AF060544.1 gb:NM_004290.1 gb:AB022663.1 AB022663 ring finger protein 14 RNF14 9604 NM_004290 /// NM_183398 /// NM_183399 /// NM_183400 /// NM_183401 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016567 // protein ubiquitination // inferred from expression pattern /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0032355 // response to estradiol stimulus // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-dependent // non-traceable author statement 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0003713 // transcription coactivator activity // non-traceable author statement /// 0003713 // transcription coactivator activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0016874 // ligase activity // inferred from electronic annotation /// 0019787 // small conjugating protein ligase activity // inferred from direct assay /// 0046872 // metal ion binding // inferred from electronic annotation /// 0050681 // androgen receptor binding // non-traceable author statement 201825_s_at AL572542 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AL572542 /FEA=EST /DB_XREF=gi:12930912 /DB_XREF=est:AL572542 /CLONE=CS0DI008YC09 (3 prime) /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1 AL572542 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // inferred from electronic annotation 201826_s_at NM_016002 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016002.1 /DEF=Homo sapiens CGI-49 protein (LOC51097), mRNA. /FEA=mRNA /GEN=LOC51097 /PROD=CGI-49 protein /DB_XREF=gi:7705766 /UG=Hs.238126 CGI-49 protein /FL=gb:AF151807.1 gb:NM_016002.1 NM_016002 saccharopine dehydrogenase (putative) SCCPDH 51097 NM_016002 0008152 // metabolic process // inferred from electronic annotation /// 0055114 // oxidation reduction // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0005488 // binding // inferred from electronic annotation /// 0016491 // oxidoreductase activity // inferred from electronic annotation /// 0047131 // saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity // inferred from electronic annotation 201827_at AF113019 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF113019.1 /DEF=Homo sapiens PRO2451 mRNA, complete cds. /FEA=mRNA /PROD=PRO2451 /DB_XREF=gi:6642761 /UG=Hs.250581 SWISNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 /FL=gb:U66618.1 gb:NM_003077.1 gb:AF113019.1 AF113019 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 SMARCD2 6603 NM_001098426 /// NM_003077 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0016514 // SWI/SNF complex // inferred from direct assay 0003713 // transcription coactivator activity // non-traceable author statement /// 0005515 // protein binding // inferred from physical interaction 201828_x_at NM_003928 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003928.1 /DEF=Homo sapiens CAAX box 1 (CXX1), mRNA. /FEA=mRNA /GEN=CXX1 /PROD=CAAX box 1 /DB_XREF=gi:4503180 /UG=Hs.250708 CAAX box 1 /FL=gb:BC002385.1 gb:BC002410.1 gb:AF038168.1 gb:AF052096.1 gb:NM_003928.1 NM_003928 family with sequence similarity 127, member A FAM127A 8933 NM_001078171 0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201829_at AW263232 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW263232 /FEA=EST /DB_XREF=gi:6640048 /DB_XREF=est:xn79e03.x1 /CLONE=IMAGE:2700700 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1 AW263232 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 201830_s_at NM_005863 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_005863.1 /DEF=Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA. /FEA=mRNA /GEN=NET1 /PROD=neuroepithelial cell transforming gene 1 /DB_XREF=gi:5031938 /UG=Hs.25155 neuroepithelial cell transforming gene 1 /FL=gb:NM_005863.1 gb:U02081.1 NM_005863 neuroepithelial cell transforming 1 NET1 10276 NM_001047160 /// NM_005863 0001558 // regulation of cell growth // non-traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007242 // intracellular signaling cascade // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0005085 // guanyl-nucleotide exchange factor activity // traceable author statement /// 0005085 // guanyl-nucleotide exchange factor activity // inferred from electronic annotation /// 0005089 // Rho guanyl-nucleotide exchange factor activity // inferred from electronic annotation 201831_s_at BE875592 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BE875592 /FEA=EST /DB_XREF=gi:10324368 /DB_XREF=est:601487031F1 /CLONE=IMAGE:3889710 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1 BE875592 USO1 homolog, vesicle docking protein (yeast) USO1 8615 NM_003715 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 201832_s_at NM_003715 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003715.1 /DEF=Homo sapiens vesicle docking protein p115 (P115), mRNA. /FEA=mRNA /GEN=P115 /PROD=vesicle docking protein p115 /DB_XREF=gi:4505540 /UG=Hs.325948 vesicle docking protein p115 /FL=gb:D86326.1 gb:NM_003715.1 NM_003715 USO1 homolog, vesicle docking protein (yeast) USO1 8615 NM_003715 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0048280 // vesicle fusion with Golgi apparatus // inferred from electronic annotation 0000139 // Golgi membrane // traceable author statement /// 0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008565 // protein transporter activity // inferred from electronic annotation 201833_at NM_001527 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001527.1 /DEF=Homo sapiens histone deacetylase 2 (HDAC2), mRNA. /FEA=mRNA /GEN=HDAC2 /PROD=histone deacetylase 2 /DB_XREF=gi:4557640 /UG=Hs.3352 histone deacetylase 2 /FL=gb:U31814.1 gb:NM_001527.1 NM_001527 histone deacetylase 2 HDAC2 3066 NM_001527 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0016568 // chromatin modification // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0016575 // histone deacetylation // inferred from electronic annotation 0000118 // histone deacetylase complex // traceable author statement /// 0000792 // heterochromatin // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // inferred from electronic annotation /// 0004407 // histone deacetylase activity // traceable author statement /// 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008134 // transcription factor binding // traceable author statement /// 0016787 // hydrolase activity // inferred from electronic annotation /// 0019899 // enzyme binding // inferred from physical interaction 201834_at BC001007 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC001007.1 /DEF=Homo sapiens, protein kinase, AMP-activated, beta 1 non-catalytic subunit, clone MGC:8608, mRNA, complete cds. /FEA=mRNA /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:12654368 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1 BC001007 protein kinase, AMP-activated, beta 1 non-catalytic subunit PRKAB1 5564 NM_006253 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 201835_s_at NM_006253 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006253.1 /DEF=Homo sapiens protein kinase, AMP-activated, beta 1 non-catalytic subunit (PRKAB1), mRNA. /FEA=mRNA /GEN=PRKAB1 /PROD=protein kinase, AMP-activated, beta 1non-catalytic subunit /DB_XREF=gi:5453967 /UG=Hs.6061 protein kinase, AMP-activated, beta 1 non-catalytic subunit /FL=gb:BC001007.1 gb:BC001056.1 gb:BC001823.1 gb:AF022116.1 gb:U83994.1 gb:NM_006253.1 NM_006253 protein kinase, AMP-activated, beta 1 non-catalytic subunit PRKAB1 5564 NM_006253 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0008610 // lipid biosynthetic process // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation /// 0016301 // kinase activity // inferred from electronic annotation 201836_s_at AU154740 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AU154740 /FEA=EST /DB_XREF=gi:11016261 /DB_XREF=est:AU154740 /CLONE=NT2RP4001989 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 AU154740 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_014860 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201837_s_at AF197954 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AF197954.1 /DEF=Homo sapiens adenocarcinoma antigen ART1 mRNA, complete cds. /FEA=mRNA /PROD=adenocarcinoma antigen ART1 /DB_XREF=gi:11066257 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 AF197954 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_014860 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201838_s_at NM_014860 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014860.1 /DEF=Homo sapiens KIAA0764 gene product (KIAA0764), mRNA. /FEA=mRNA /GEN=KIAA0764 /PROD=KIAA0764 gene product /DB_XREF=gi:7662291 /UG=Hs.6232 KIAA0764 gene product /FL=gb:AF197954.1 gb:AB018307.1 gb:NM_014860.1 NM_014860 suppressor of Ty 7 (S. cerevisiae)-like SUPT7L 9913 NM_014860 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0051457 // maintenance of protein location in nucleus // inferred from direct assay 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction 201839_s_at NM_002354 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002354.1 /DEF=Homo sapiens tumor-associated calcium signal transducer 1 (TACSTD1), mRNA. /FEA=mRNA /GEN=TACSTD1 /PROD=tumor-associated calcium signal transducer 1precursor /DB_XREF=gi:4505058 /UG=Hs.692 tumor-associated calcium signal transducer 1 /FL=gb:M32306.1 gb:M33011.1 gb:NM_002354.1 NM_002354 epithelial cell adhesion molecule EPCAM 4072 NM_002354 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 201840_at NM_006156 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006156.1 /DEF=Homo sapiens neural precursor cell expressed, developmentally down-regulated 8 (NEDD8), mRNA. /FEA=mRNA /GEN=NEDD8 /PROD=neural precursor cell expressed, developmentallydown-regulated 8 /DB_XREF=gi:5453759 /UG=Hs.75512 neural precursor cell expressed, developmentally down-regulated 8 /FL=gb:D23662.1 gb:NM_006156.1 NM_006156 neural precursor cell expressed, developmentally down-regulated 8 NEDD8 4738 NM_006156 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006464 // protein modification process // traceable author statement /// 0006464 // protein modification process // inferred from electronic annotation /// 0006508 // proteolysis // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0008104 // protein localization // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0045116 // protein neddylation // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from electronic annotation 201841_s_at NM_001540 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001540.2 /DEF=Homo sapiens heat shock 27kD protein 1 (HSPB1), mRNA. /FEA=mRNA /GEN=HSPB1 /PROD=heat shock 27kD protein 1 /DB_XREF=gi:4996892 /UG=Hs.76067 heat shock 27kD protein 1 /FL=gb:AB020027.1 gb:BC000510.1 gb:U90906.1 gb:NM_001540.2 NM_001540 heat shock 27kDa protein 1 HSPB1 3315 NM_001540 0006446 // regulation of translational initiation // traceable author statement /// 0006916 // anti-apoptosis // traceable author statement /// 0006928 // cell motion // traceable author statement /// 0006950 // response to stress // inferred from electronic annotation /// 0006986 // response to unfolded protein // traceable author statement /// 0009408 // response to heat // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement /// 0009986 // cell surface // inferred from direct assay 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction 201842_s_at AI826799 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI826799 /FEA=EST /DB_XREF=gi:5447470 /DB_XREF=est:wk56d07.x1 /CLONE=IMAGE:2419405 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2 AI826799 EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 0007601 // visual perception // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201843_s_at NM_004105 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004105.2 /DEF=Homo sapiens EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 1, mRNA. /FEA=mRNA /GEN=EFEMP1 /PROD=EGF-containing fibulin-like extracellular matrixprotein 1 precursor, isoform a precursor /DB_XREF=gi:9665261 /UG=Hs.76224 EGF-containing fibulin-like extracellular matrix protein 1 /FL=gb:U03877.1 gb:NM_004105.2 NM_004105 EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 2202 NM_001039348 /// NM_001039349 /// NM_004105 0007601 // visual perception // traceable author statement 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // traceable author statement 0005509 // calcium ion binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201844_s_at W84482 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:W84482 /FEA=EST /DB_XREF=gi:1395613 /DB_XREF=est:zd89h07.s1 /CLONE=IMAGE:356701 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 W84482 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201845_s_at AB029551 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:AB029551.1 /DEF=Homo sapiens YEAF1 mRNA for YY1 and E4TF1 associated factor 1, complete cds. /FEA=mRNA /GEN=YEAF1 /PROD=YY1 and E4TF1 associated factor 1 /DB_XREF=gi:6714542 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 AB029551 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201846_s_at NM_012234 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_012234.1 /DEF=Homo sapiens RING1 and YY1 binding protein (RYBP), mRNA. /FEA=mRNA /GEN=RYBP /PROD=RING1 and YY1 binding protein /DB_XREF=gi:6912639 /UG=Hs.7910 RING1 and YY1 binding protein /FL=gb:AF179286.1 gb:AB029551.1 gb:NM_012234.1 NM_012234 RING1 and YY1 binding protein RYBP 23429 NM_012234 0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006915 // apoptosis // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003677 // DNA binding // inferred from electronic annotation /// 0003714 // transcription corepressor activity // traceable author statement /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201847_at NM_000235 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000235.1 /DEF=Homo sapiens lipase A, lysosomal acid, cholesterol esterase (Wolman disease) (LIPA), mRNA. /FEA=mRNA /GEN=LIPA /PROD=lipase A precursor /DB_XREF=gi:4557720 /UG=Hs.85226 lipase A, lysosomal acid, cholesterol esterase (Wolman disease) /FL=gb:M74775.1 gb:NM_000235.1 gb:U08464.1 NM_000235 lipase A, lysosomal acid, cholesterol esterase LIPA 3988 NM_000235 /// NM_001127605 0006487 // protein amino acid N-linked glycosylation // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0016042 // lipid catabolic process // inferred from electronic annotation 0005764 // lysosome // traceable author statement /// 0005764 // lysosome // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004437 // inositol or phosphatidylinositol phosphatase activity // inferred from electronic annotation /// 0004771 // sterol esterase activity // inferred from electronic annotation /// 0016298 // lipase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201848_s_at U15174 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:U15174.1 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3) mRNA, complete cds. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:558845 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2 U15174 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // DNA fragmentation during apoptosis // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006800 // oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from physical interaction /// 0006916 // anti-apoptosis // traceable author statement /// 0006917 // induction of apoptosis // inferred from direct assay /// 0008219 // cell death // inferred from direct assay /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008634 // negative regulation of survival gene product expression // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0051402 // neuron apoptosis // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral to mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201849_at NM_004052 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004052.2 /DEF=Homo sapiens BCL2adenovirus E1B 19kD-interacting protein 3 (BNIP3), nuclear gene encoding mitochondrial protein, mRNA. /FEA=mRNA /GEN=BNIP3 /PROD=BCL2adenovirus E1B 19kD-interacting protein 3 /DB_XREF=gi:7669480 /UG=Hs.79428 BCL2adenovirus E1B 19kD-interacting protein 3 /FL=gb:AF002697.1 gb:U15174.1 gb:NM_004052.2 NM_004052 BCL2/adenovirus E1B 19kDa interacting protein 3 BNIP3 664 NM_004052 0001666 // response to hypoxia // inferred from sequence or structural similarity /// 0006309 // DNA fragmentation during apoptosis // inferred from direct assay /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006800 // oxygen and reactive oxygen species metabolic process // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0006915 // apoptosis // inferred from physical interaction /// 0006916 // anti-apoptosis // traceable author statement /// 0006917 // induction of apoptosis // inferred from direct assay /// 0008219 // cell death // inferred from direct assay /// 0008219 // cell death // inferred from sequence or structural similarity /// 0008634 // negative regulation of survival gene product expression // inferred from direct assay /// 0043065 // positive regulation of apoptosis // inferred from electronic annotation /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation /// 0045837 // negative regulation of membrane potential // inferred from direct assay /// 0046902 // regulation of mitochondrial membrane permeability // inferred from direct assay /// 0051402 // neuron apoptosis // inferred from sequence or structural similarity /// 0051607 // defense response to virus // inferred from direct assay 0005634 // nucleus // inferred from sequence or structural similarity /// 0005635 // nuclear envelope // inferred from direct assay /// 0005654 // nucleoplasm // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // traceable author statement /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005740 // mitochondrial envelope // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation /// 0030425 // dendrite // inferred from sequence or structural similarity /// 0031307 // integral to mitochondrial outer membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from direct assay /// 0031966 // mitochondrial membrane // inferred from mutant phenotype /// 0031966 // mitochondrial membrane // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0042802 // identical protein binding // inferred from physical interaction /// 0042803 // protein homodimerization activity // inferred from direct assay /// 0046982 // protein heterodimerization activity // inferred from direct assay 201850_at NM_001747 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001747.1 /DEF=Homo sapiens capping protein (actin filament), gelsolin-like (CAPG), mRNA. /FEA=mRNA /GEN=CAPG /PROD=capping protein (actin filament), gelsolin-like /DB_XREF=gi:4502560 /UG=Hs.82422 capping protein (actin filament), gelsolin-like /FL=gb:BC000728.1 gb:M94345.1 gb:NM_001747.1 NM_001747 capping protein (actin filament), gelsolin-like CAPG 822 NM_001747 0006461 // protein complex assembly // non-traceable author statement /// 0030031 // cell projection assembly // inferred from electronic annotation /// 0051016 // barbed-end actin filament capping // traceable author statement /// 0051016 // barbed-end actin filament capping // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0008290 // F-actin capping protein complex // traceable author statement /// 0042470 // melanosome // inferred from electronic annotation 0003779 // actin binding // inferred from electronic annotation 201851_at NM_003025 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_003025.1 /DEF=Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA. /FEA=mRNA /GEN=SH3GL1 /PROD=SH3-domain GRB2-like 1 /DB_XREF=gi:4506928 /UG=Hs.97616 SH3-domain GRB2-like 1 /FL=gb:BC001270.1 gb:U65999.1 gb:NM_003025.1 NM_003025 SH3-domain GRB2-like 1 SH3GL1 6455 NM_003025 0006897 // endocytosis // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007417 // central nervous system development // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0031901 // early endosome membrane // inferred from electronic annotation 0005515 // protein binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008289 // lipid binding // inferred from electronic annotation 201852_x_at AI813758 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI813758 /FEA=EST /DB_XREF=gi:5424973 /DB_XREF=est:wk79b04.x1 /CLONE=IMAGE:2421583 /UG=Hs.119571 collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) /FL=gb:NM_000090.1 AI813758 collagen, type III, alpha 1 COL3A1 1281 NM_000090 0007160 // cell-matrix adhesion // inferred from direct assay /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007229 // integrin-mediated signaling pathway // inferred from mutant phenotype /// 0007507 // heart development // inferred from mutant phenotype /// 0009314 // response to radiation // inferred from direct assay /// 0018149 // peptide cross-linking // inferred from direct assay /// 0030168 // platelet activation // non-traceable author statement /// 0030199 // collagen fibril organization // inferred from mutant phenotype /// 0030199 // collagen fibril organization // non-traceable author statement /// 0032964 // collagen biosynthetic process // inferred from mutant phenotype /// 0032964 // collagen biosynthetic process // traceable author statement /// 0034097 // response to cytokine stimulus // inferred from direct assay /// 0042060 // wound healing // inferred from direct assay /// 0042060 // wound healing // non-traceable author statement /// 0043206 // fibril organization // inferred from mutant phenotype /// 0043588 // skin development // inferred from mutant phenotype /// 0050777 // negative regulation of immune response // inferred from mutant phenotype 0005576 // extracellular region // inferred from electronic annotation /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005581 // collagen // inferred from electronic annotation /// 0005586 // collagen type III // inferred from mutant phenotype /// 0005586 // collagen type III // non-traceable author statement /// 0005586 // collagen type III // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005615 // extracellular space // non-traceable author statement /// 0031012 // extracellular matrix // inferred from mutant phenotype 0005178 // integrin binding // inferred from mutant phenotype /// 0005178 // integrin binding // non-traceable author statement /// 0005201 // extracellular matrix structural constituent // inferred from mutant phenotype /// 0005201 // extracellular matrix structural constituent // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0048407 // platelet-derived growth factor binding // inferred from direct assay 201853_s_at NM_021873 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_021873.1 /DEF=Homo sapiens cell division cycle 25B (CDC25B), transcript variant 3, mRNA. /FEA=mRNA /GEN=CDC25B /PROD=cell division cycle 25B, isoform 3 /DB_XREF=gi:11641412 /UG=Hs.153752 cell division cycle 25B /FL=gb:NM_021873.1 NM_021873 cell division cycle 25 homolog B (S. pombe) CDC25B 994 NM_004358 /// NM_021872 /// NM_021873 0000087 // M phase of mitotic cell cycle // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0001556 // oocyte maturation // inferred from electronic annotation /// 0006470 // protein amino acid dephosphorylation // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitosis // traceable author statement /// 0007067 // mitosis // inferred from electronic annotation /// 0007144 // female meiosis I // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005622 // intracellular // non-traceable author statement /// 0005654 // nucleoplasm // not recorded /// 0005813 // centrosome // inferred from electronic annotation /// 0005829 // cytosol // not recorded 0004721 // phosphoprotein phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // inferred from electronic annotation /// 0004725 // protein tyrosine phosphatase activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016787 // hydrolase activity // inferred from electronic annotation 201854_s_at AI744148 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI744148 /FEA=EST /DB_XREF=gi:5112436 /DB_XREF=est:wc36h01.x1 /CLONE=IMAGE:2317297 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1 AI744148 ATM interactor ATMIN 23300 NM_015251 0006974 // response to DNA damage stimulus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201855_s_at NM_015251 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015251.1 /DEF=Homo sapiens KIAA0431 protein (KIAA0431), mRNA. /FEA=mRNA /GEN=KIAA0431 /PROD=KIAA0431 protein /DB_XREF=gi:7662115 /UG=Hs.16349 KIAA0431 protein /FL=gb:NM_015251.1 NM_015251 ATM interactor ATMIN 23300 NM_015251 0006974 // response to DNA damage stimulus // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201856_s_at BC000376 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:BC000376.1 /DEF=Homo sapiens, clone MGC:8379, mRNA, complete cds. /FEA=mRNA /PROD=Unknown (protein for MGC:8379) /DB_XREF=gi:12653216 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1 BC000376 zinc finger RNA binding protein ZFR 51663 NM_016107 0007275 // multicellular organismal development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201857_at NM_016107 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_016107.1 /DEF=Homo sapiens M-phase phosphoprotein homolog (LOC51663), mRNA. /FEA=mRNA /GEN=LOC51663 /PROD=M-phase phosphoprotein homolog /DB_XREF=gi:7706372 /UG=Hs.173518 M-phase phosphoprotein homolog /FL=gb:BC000376.1 gb:BC000746.1 gb:AF100742.1 gb:NM_016107.1 NM_016107 zinc finger RNA binding protein ZFR 51663 NM_016107 0007275 // multicellular organismal development // inferred from electronic annotation 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201858_s_at J03223 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:J03223.1 /DEF=Human secretory granule proteoglycan peptide core mRNA, complete cds. /FEA=mRNA /GEN=PRG1 /DB_XREF=gi:190419 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1 J03223 serglycin SRGN 5552 NM_002727 0001503 // ossification // inferred from electronic annotation /// 0006915 // apoptosis // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033364 // mast cell secretory granule organization // inferred from electronic annotation /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from electronic annotation /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from electronic annotation /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0051605 // protein maturation via proteolysis // inferred from sequence or structural similarity /// 0051605 // protein maturation via proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity /// 0042629 // mast cell granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 201859_at NM_002727 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002727.1 /DEF=Homo sapiens proteoglycan 1, secretory granule (PRG1), mRNA. /FEA=mRNA /GEN=PRG1 /PROD=proteoglycan 1, secretory granule /DB_XREF=gi:4506044 /UG=Hs.1908 proteoglycan 1, secretory granule /FL=gb:J03223.1 gb:NM_002727.1 NM_002727 serglycin SRGN 5552 NM_002727 0001503 // ossification // inferred from electronic annotation /// 0006915 // apoptosis // inferred from direct assay /// 0006915 // apoptosis // inferred from electronic annotation /// 0030502 // negative regulation of bone mineralization // inferred from direct assay /// 0033364 // mast cell secretory granule organization // inferred from sequence or structural similarity /// 0033364 // mast cell secretory granule organization // inferred from electronic annotation /// 0033371 // T cell secretory granule organization // inferred from sequence or structural similarity /// 0033371 // T cell secretory granule organization // inferred from electronic annotation /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from sequence or structural similarity /// 0033373 // maintenance of protease location in mast cell secretory granule // inferred from electronic annotation /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from sequence or structural similarity /// 0033382 // maintenance of granzyme B location in T cell secretory granule // inferred from electronic annotation /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from electronic annotation /// 0051605 // protein maturation via proteolysis // inferred from sequence or structural similarity /// 0051605 // protein maturation via proteolysis // inferred from electronic annotation 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0042629 // mast cell granule // inferred from sequence or structural similarity /// 0042629 // mast cell granule // inferred from electronic annotation 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // inferred from sequence or structural similarity /// 0005515 // protein binding // inferred from electronic annotation 201860_s_at NM_000930 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000930.1 /DEF=Homo sapiens plasminogen activator, tissue (PLAT), mRNA. /FEA=mRNA /GEN=PLAT /PROD=plasminogen activator, tissue /DB_XREF=gi:4505860 /UG=Hs.274404 plasminogen activator, tissue /FL=gb:NM_000931.1 gb:M15518.1 gb:M18182.1 gb:NM_000930.1 NM_000930 plasminogen activator, tissue PLAT 5327 NM_000930 /// NM_033011 0001666 // response to hypoxia // inferred from electronic annotation /// 0006464 // protein modification process // traceable author statement /// 0006508 // proteolysis // traceable author statement /// 0006508 // proteolysis // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0014909 // smooth muscle cell migration // inferred from electronic annotation /// 0048008 // platelet-derived growth factor receptor signaling pathway // inferred from electronic annotation 0005576 // extracellular region // not recorded /// 0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from direct assay /// 0030141 // secretory granule // inferred from electronic annotation /// 0045177 // apical part of cell // inferred from electronic annotation 0003824 // catalytic activity // inferred from electronic annotation /// 0004252 // serine-type endopeptidase activity // inferred from electronic annotation /// 0008233 // peptidase activity // inferred from electronic annotation /// 0008236 // serine-type peptidase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201861_s_at BF965566 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF965566 /FEA=EST /DB_XREF=gi:12332781 /DB_XREF=est:602277032F1 /CLONE=IMAGE:4364790 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1 BF965566 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016481 // negative regulation of transcription // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // non-traceable author statement 201862_s_at NM_004735 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_004735.1 /DEF=Homo sapiens leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), mRNA. /FEA=mRNA /GEN=LRRFIP1 /PROD=leucine rich repeat (in FLII) interactingprotein 1 /DB_XREF=gi:4758689 /UG=Hs.326159 leucine rich repeat (in FLII) interacting protein 1 /FL=gb:NM_004735.1 NM_004735 leucine rich repeat (in FLII) interacting protein 1 LRRFIP1 9208 NM_001137550 /// NM_001137551 /// NM_001137552 /// NM_001137553 /// NM_004735 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0016481 // negative regulation of transcription // non-traceable author statement 0005634 // nucleus // non-traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // traceable author statement 0000166 // nucleotide binding // inferred from electronic annotation /// 0003676 // nucleic acid binding // inferred from electronic annotation /// 0003677 // DNA binding // inferred from electronic annotation /// 0003723 // RNA binding // inferred from electronic annotation /// 0003725 // double-stranded RNA binding // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0016564 // transcription repressor activity // non-traceable author statement 201863_at NM_014077 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_014077.1 /DEF=Homo sapiens DKFZP586O0120 protein (DKFZP586O0120), mRNA. /FEA=mRNA /GEN=DKFZP586O0120 /PROD=DKFZP586O0120 protein /DB_XREF=gi:7661695 /UG=Hs.4766 DKFZP586O0120 protein /FL=gb:BC000639.1 gb:AL050157.1 gb:AF151902.1 gb:NM_014077.1 NM_014077 family with sequence similarity 32, member A FAM32A 26017 NM_014077 0005730 // nucleolus // inferred from direct assay 201864_at NM_001493 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_001493.1 /DEF=Homo sapiens GDP dissociation inhibitor 1 (GDI1), mRNA. /FEA=mRNA /GEN=GDI1 /PROD=GDP dissociation inhibitor 1 /DB_XREF=gi:4503970 /UG=Hs.74576 GDP dissociation inhibitor 1 /FL=gb:BC000317.1 gb:NM_001493.1 gb:D45021.1 NM_001493 GDP dissociation inhibitor 1 GDI1 2664 NM_001493 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from electronic annotation 0005624 // membrane fraction // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay 0005092 // GDP-dissociation inhibitor activity // traceable author statement /// 0005093 // Rab GDP-dissociation inhibitor activity // inferred from electronic annotation /// 0005096 // GTPase activator activity // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201865_x_at AI432196 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI432196 /FEA=EST /DB_XREF=gi:4308490 /DB_XREF=est:tg77g05.x1 /CLONE=IMAGE:2114840 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1 AI432196 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 0006350 // transcription // inferred from electronic annotation /// 0006351 // transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007530 // sex determination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0051789 // response to protein stimulus // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // traceable author statement /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201866_s_at NM_000176 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000176.1 /DEF=Homo sapiens nuclear receptor subfamily 3, group C, member 1 (NR3C1), mRNA. /FEA=mRNA /GEN=NR3C1 /PROD=nuclear receptor subfamily 3, group C, member 1 /DB_XREF=gi:4504132 /UG=Hs.75772 nuclear receptor subfamily 3, group C, member 1 /FL=gb:M10901.1 gb:NM_000176.1 NM_000176 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) NR3C1 2908 NM_000176 /// NM_001018074 /// NM_001018075 /// NM_001018076 /// NM_001018077 /// NM_001020825 /// NM_001024094 0006350 // transcription // inferred from electronic annotation /// 0006351 // transcription, DNA-dependent // traceable author statement /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007530 // sex determination // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0051789 // response to protein stimulus // inferred from direct assay 0005634 // nucleus // traceable author statement /// 0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005759 // mitochondrial matrix // traceable author statement 0003677 // DNA binding // inferred from electronic annotation /// 0003700 // transcription factor activity // traceable author statement /// 0003700 // transcription factor activity // inferred from electronic annotation /// 0003707 // steroid hormone receptor activity // inferred from electronic annotation /// 0004872 // receptor activity // inferred from electronic annotation /// 0004879 // ligand-dependent nuclear receptor activity // inferred from electronic annotation /// 0004883 // glucocorticoid receptor activity // traceable author statement /// 0004883 // glucocorticoid receptor activity // inferred from electronic annotation /// 0005496 // steroid binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008270 // zinc ion binding // inferred from electronic annotation /// 0008289 // lipid binding // inferred from electronic annotation /// 0043565 // sequence-specific DNA binding // inferred from electronic annotation /// 0046872 // metal ion binding // inferred from electronic annotation 201867_s_at AW968555 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AW968555 /FEA=EST /DB_XREF=gi:8158396 /DB_XREF=est:EST380631 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AW968555 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 201868_s_at AI082187 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI082187 /FEA=EST /DB_XREF=gi:3418979 /DB_XREF=est:ox75f01.x1 /CLONE=IMAGE:1662169 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 AI082187 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 201869_s_at BF593932 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF593932 /FEA=EST /DB_XREF=gi:11686256 /DB_XREF=est:nab48e09.x1 /CLONE=IMAGE:3269104 /UG=Hs.76536 transducin (beta)-like 1 /FL=gb:NM_005647.1 BF593932 transducin (beta)-like 1X-linked TBL1X 6907 NM_001139466 /// NM_001139467 /// NM_001139468 /// NM_005647 0006350 // transcription // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-dependent // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007601 // visual perception // traceable author statement /// 0007605 // sensory perception of sound // traceable author statement /// 0007605 // sensory perception of sound // inferred from electronic annotation 0005634 // nucleus // inferred from electronic annotation 201870_at NM_006809 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_006809.1 /DEF=Homo sapiens translocase of outer mitochondrial membrane 34 (TOM34), mRNA. /FEA=mRNA /GEN=TOM34 /PROD=translocase of outer mitochondrial membrane 34 /DB_XREF=gi:5803204 /UG=Hs.76927 translocase of outer mitochondrial membrane 34 /FL=gb:BC001763.1 gb:U58970.1 gb:NM_006809.1 NM_006809 translocase of outer mitochondrial membrane 34 TOMM34 10953 NM_006809 0006626 // protein targeting to mitochondrion // traceable author statement 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // traceable author statement /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // traceable author statement 0004872 // receptor activity // inferred from electronic annotation /// 0005048 // signal sequence binding // traceable author statement /// 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction 201871_s_at NM_015853 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_015853.1 /DEF=Homo sapiens ORF (LOC51035), mRNA. /FEA=mRNA /GEN=LOC51035 /PROD=unknown protein LOC51035 /DB_XREF=gi:7705653 /UG=Hs.77868 ORF /FL=gb:BC000902.1 gb:M68864.1 gb:NM_015853.1 NM_015853 UBX domain protein 1 UBXN1 51035 NM_015853 0043161 // proteasomal ubiquitin-dependent protein catabolic process // non-traceable author statement 0000502 // proteasome complex // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation 0031593 // polyubiquitin binding // inferred from direct assay /// 0051117 // ATPase binding // inferred from physical interaction 201872_s_at AI002002 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:AI002002 /FEA=EST /DB_XREF=gi:3202473 /DB_XREF=est:ot42e10.s1 /CLONE=IMAGE:1619466 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1 AI002002 ATP-binding cassette, sub-family E (OABP), member 1 ABCE1 6059 NM_001040876 /// NM_002940 0006401 // RNA catabolic process // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201873_s_at NM_002940 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002940.1 /DEF=Homo sapiens ATP-binding cassette, sub-family E (OABP), member 1 (ABCE1), mRNA. /FEA=mRNA /GEN=ABCE1 /PROD=ATP-binding cassette, sub-family E, member 1 /DB_XREF=gi:4506558 /UG=Hs.12013 ATP-binding cassette, sub-family E (OABP), member 1 /FL=gb:NM_002940.1 NM_002940 ATP-binding cassette, sub-family E (OABP), member 1 ABCE1 6059 NM_001040876 /// NM_002940 0006401 // RNA catabolic process // traceable author statement /// 0009615 // response to virus // traceable author statement /// 0044419 // interspecies interaction between organisms // inferred from electronic annotation 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation 0000166 // nucleotide binding // inferred from electronic annotation /// 0005524 // ATP binding // inferred from electronic annotation /// 0008428 // ribonuclease inhibitor activity // traceable author statement /// 0009055 // electron carrier activity // inferred from electronic annotation /// 0016887 // ATPase activity // inferred from electronic annotation /// 0017111 // nucleoside-triphosphatase activity // inferred from electronic annotation /// 0051536 // iron-sulfur cluster binding // inferred from electronic annotation 201874_at BF978611 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:BF978611 /FEA=EST /DB_XREF=gi:12345826 /DB_XREF=est:602149061F1 /CLONE=IMAGE:4307822 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1 BF978611 myelin protein zero-like 1 MPZL1 9019 NM_003953 /// NM_024569 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement 201875_s_at NM_024569 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_024569.1 /DEF=Homo sapiens hypothetical protein FLJ21047 (FLJ21047), mRNA. /FEA=mRNA /GEN=FLJ21047 /PROD=hypothetical protein FLJ21047 /DB_XREF=gi:13375739 /UG=Hs.14891 hypothetical protein FLJ21047 /FL=gb:NM_024569.1 NM_024569 myelin protein zero-like 1 MPZL1 9019 NM_003953 /// NM_024569 0007169 // transmembrane receptor protein tyrosine kinase signaling pathway // traceable author statement /// 0007267 // cell-cell signaling // traceable author statement 0005887 // integral to plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from electronic annotation 0005198 // structural molecule activity // traceable author statement /// 0005515 // protein binding // inferred from physical interaction /// 0005515 // protein binding // traceable author statement 201876_at NM_000305 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_000305.1 /DEF=Homo sapiens paraoxonase 2 (PON2), mRNA. /FEA=mRNA /GEN=PON2 /PROD=paraoxonase 2 /DB_XREF=gi:4505952 /UG=Hs.169857 paraoxonase 2 /FL=gb:L48513.1 gb:AF001601.1 gb:NM_000305.1 NM_000305 paraoxonase 2 PON2 5445 NM_000305 /// NM_001018161 0005576 // extracellular region // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation 0004063 // aryldialkylphosphatase activity // inferred from electronic annotation /// 0004064 // arylesterase activity // traceable author statement /// 0004064 // arylesterase activity // inferred from electronic annotation /// 0016787 // hydrolase activity // inferred from electronic annotation 201877_s_at NM_002719 Homo sapiens Mar 11, 2009 Exemplar sequence GenBank gb:NM_002719.1 /DEF=Homo sapiens protein phosphatase 2, regulatory subunit B (B56), gamma isoform (PPP2R5C), mRNA. /FEA=mRNA /GEN=PPP2R5C /PROD=protein phosphatase 2, regulatory subunit B(B56), gamma isoform /DB_XREF=gi:4506022 /UG=Hs.171734 protein phosphatase 2, regulatory subunit B (B56), gamma isoform /FL=gb:U37352.1 gb:NM_002719.1 NM_002719 protein phosphatase 2, regulatory subunit B', gamma isoform PPP2R5C 5527 NM_002719 /// NM_178586 /// NM_178587 /// NM_178588 0007165 // signal transduction // inferred from electronic annotation /// 0007165 // signal transduction // non-traceable author statement /// 0016485 // protein processing // inferred from direct assay 0000159 // protein phosphatase type 2A complex // inferred from electronic annotation /// 0000159 // protein phosphatase type 2A complex // non-traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0016021 // integral to membrane // inferred from direct assay 0005488 // binding // inferred from electronic annotation /// 0005515 // protein binding // inferred from physical interaction /// 0008233 // peptidase activity // inferred from direct assay /// 0008601 // protein phosphatase type 2A regulator activity // inferred from electronic annotation /// 0008601 // protein phosphatase type 2A regulator activity // non-traceable author statement 201878_at N25546 Homo sapiens Mar 11, 2009 Consensus sequence GenBank Consensus includes gb:N25546 /FEA=EST /DB_XREF=gi:1139894 /DB_XREF=est:yx76e05.s1 /CLONE=IMAGE:267680 /UG=Hs.181461 ariadne (Drosophila) homolog, ubiquitin-conjugating enzyme E2-binding protein, 1 /FL=gb:AF072832.1 gb:NM_005744.2 N25546 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) ARIH1 25820 NM_005744 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation ///